메뉴 건너뛰기




Volumn 49, Issue 1, 2008, Pages 73-84

Development of an inducible gene expression system for primary murine keratinocytes

Author keywords

Differentiation; Keratinocytes; Stable transfection; Tet inducibility

Indexed keywords

TETRACYCLINE; TRANSCRIPTION FACTOR AP 2; TRANSCRIPTION FACTOR AP 2ALPHA; UNCLASSIFIED DRUG;

EID: 36849082034     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2007.09.003     Document Type: Article
Times cited : (6)

References (42)
  • 1
    • 0035545301 scopus 로고    scopus 로고
    • An improved method for culture of epidermal keratinocytes from newborn mouse skin
    • Hakkinen L., Koivisto L., and Larjava H. An improved method for culture of epidermal keratinocytes from newborn mouse skin. Methods Cell Sci 23 (2001) 189-196
    • (2001) Methods Cell Sci , vol.23 , pp. 189-196
    • Hakkinen, L.1    Koivisto, L.2    Larjava, H.3
  • 2
    • 16644389765 scopus 로고    scopus 로고
    • Experimental models to analyze differentiation functions of cultured keratinocytes in vitro and in vivo
    • Turksen K. (Ed), Humana Press Totowa, New Jersey
    • Maas-Szabowski N., Fusenig N.E., and Stark H.J. Experimental models to analyze differentiation functions of cultured keratinocytes in vitro and in vivo. In: Turksen K. (Ed). Epidermal cells: methods and protocols (2005), Humana Press Totowa, New Jersey 47-60
    • (2005) Epidermal cells: methods and protocols , pp. 47-60
    • Maas-Szabowski, N.1    Fusenig, N.E.2    Stark, H.J.3
  • 3
    • 3242701181 scopus 로고    scopus 로고
    • Long-term murine keratinocyte cultures become tetraploid, yet maintain the ability to stratify
    • Bruegel Sanchez V.L., Zhou J., LaCivita D., and Milstone L.M. Long-term murine keratinocyte cultures become tetraploid, yet maintain the ability to stratify. J Invest Dermatol 123 (2004) 403-404
    • (2004) J Invest Dermatol , vol.123 , pp. 403-404
    • Bruegel Sanchez, V.L.1    Zhou, J.2    LaCivita, D.3    Milstone, L.M.4
  • 4
    • 0030935565 scopus 로고    scopus 로고
    • The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation
    • Eckert R.L., Crish J.F., and Robinson N.A. The epidermal keratinocyte as a model for the study of gene regulation and cell differentiation. Physiol Rev 77 (1997) 397-424
    • (1997) Physiol Rev , vol.77 , pp. 397-424
    • Eckert, R.L.1    Crish, J.F.2    Robinson, N.A.3
  • 5
    • 13544259736 scopus 로고    scopus 로고
    • Cellular and molecular facets of keratinocyte reepithelization during wound healing
    • Santoro M.M., and Gaudino G. Cellular and molecular facets of keratinocyte reepithelization during wound healing. Exp Cell Res 304 (2005) 274-286
    • (2005) Exp Cell Res , vol.304 , pp. 274-286
    • Santoro, M.M.1    Gaudino, G.2
  • 6
    • 16644380416 scopus 로고    scopus 로고
    • Primary mouse keratinocyte culture
    • Turksen K. (Ed), Humana Press Totowa, New Jersey
    • Pirrone A., Hager B., and Fleckman P. Primary mouse keratinocyte culture. In: Turksen K. (Ed). Epidermal cells: methods and protocols (2005), Humana Press Totowa, New Jersey 3-14
    • (2005) Epidermal cells: methods and protocols , pp. 3-14
    • Pirrone, A.1    Hager, B.2    Fleckman, P.3
  • 7
    • 0018865014 scopus 로고
    • Calcium regulation of growth and differentiation of mouse epidermal cells in culture
    • Hennings H., Michael D., Cheng C., Steinert P., Holbrook K., and Yuspa S.H. Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell 19 (1980) 245-254
    • (1980) Cell , vol.19 , pp. 245-254
    • Hennings, H.1    Michael, D.2    Cheng, C.3    Steinert, P.4    Holbrook, K.5    Yuspa, S.H.6
  • 8
    • 0024454035 scopus 로고
    • Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro
    • Yuspa S.H., Kilkenny A.E., Steinert P.M., and Roop D.R. Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol 109 (1989) 1207-1217
    • (1989) J Cell Biol , vol.109 , pp. 1207-1217
    • Yuspa, S.H.1    Kilkenny, A.E.2    Steinert, P.M.3    Roop, D.R.4
  • 9
    • 0021683955 scopus 로고
    • Mouse epidermal keratinocytes. Clonal proliferation and response to hormones and growth factors in serum-free medium
    • Bertolero F., Kaighn M.E., Gonda M.A., and Saffiotti U. Mouse epidermal keratinocytes. Clonal proliferation and response to hormones and growth factors in serum-free medium. Exp Cell Res 155 (1984) 64-80
    • (1984) Exp Cell Res , vol.155 , pp. 64-80
    • Bertolero, F.1    Kaighn, M.E.2    Gonda, M.A.3    Saffiotti, U.4
  • 10
    • 0032473931 scopus 로고    scopus 로고
    • Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation
    • Greenberg R.A., Allsopp R.C., Chin L., Morin G.B., and DePinho R.A. Expression of mouse telomerase reverse transcriptase during development, differentiation and proliferation. Oncogene 16 (1998) 1723-1730
    • (1998) Oncogene , vol.16 , pp. 1723-1730
    • Greenberg, R.A.1    Allsopp, R.C.2    Chin, L.3    Morin, G.B.4    DePinho, R.A.5
  • 11
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M., and Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc Natl Acad Sci USA 89 (1992) 5547-5551
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 12
    • 0027501690 scopus 로고
    • Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements
    • Gossen M., Bonin A.L., and Bujard H. Control of gene activity in higher eukaryotic cells by prokaryotic regulatory elements. Trends Biochem Sci 18 (1993) 471-475
    • (1993) Trends Biochem Sci , vol.18 , pp. 471-475
    • Gossen, M.1    Bonin, A.L.2    Bujard, H.3
  • 13
    • 0025275853 scopus 로고
    • c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy
    • Boukamp P., Stanbridge E.J., Foo D.Y., Cerutti P.A., and Fusenig N.E. c-Ha-ras oncogene expression in immortalized human keratinocytes (HaCaT) alters growth potential in vivo but lacks correlation with malignancy. Cancer Res 50 (1990) 2840-2847
    • (1990) Cancer Res , vol.50 , pp. 2840-2847
    • Boukamp, P.1    Stanbridge, E.J.2    Foo, D.Y.3    Cerutti, P.A.4    Fusenig, N.E.5
  • 14
    • 33644649121 scopus 로고    scopus 로고
    • The suppressor of cytokine signaling-3 is upregulated in impaired skin repair: implications for keratinocyte proliferation
    • Goren I., Linke A., Muller E., Pfeilschifter J., and Frank S. The suppressor of cytokine signaling-3 is upregulated in impaired skin repair: implications for keratinocyte proliferation. J Invest Dermatol 126 (2006) 477-485
    • (2006) J Invest Dermatol , vol.126 , pp. 477-485
    • Goren, I.1    Linke, A.2    Muller, E.3    Pfeilschifter, J.4    Frank, S.5
  • 15
    • 0042268512 scopus 로고    scopus 로고
    • Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes
    • Berens C., and Hillen W. Gene regulation by tetracyclines. Constraints of resistance regulation in bacteria shape TetR for application in eukaryotes. Eur J Biochem 270 (2003) 3109-3121
    • (2003) Eur J Biochem , vol.270 , pp. 3109-3121
    • Berens, C.1    Hillen, W.2
  • 16
    • 0036956875 scopus 로고    scopus 로고
    • Studying gene function in eukaryotes by conditional gene inactivation
    • Gossen M., and Bujard H. Studying gene function in eukaryotes by conditional gene inactivation. Annu Rev Genet 36 (2002) 153-173
    • (2002) Annu Rev Genet , vol.36 , pp. 153-173
    • Gossen, M.1    Bujard, H.2
  • 18
    • 0034608802 scopus 로고    scopus 로고
    • Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity
    • Urlinger S., Baron U., Thellmann M., Hasan M.T., Bujard H., and Hillen W. Exploring the sequence space for tetracycline-dependent transcriptional activators: novel mutations yield expanded range and sensitivity. Proc Natl Acad Sci USA 97 (2000) 7963-7968
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 7963-7968
    • Urlinger, S.1    Baron, U.2    Thellmann, M.3    Hasan, M.T.4    Bujard, H.5    Hillen, W.6
  • 19
    • 0442307865 scopus 로고    scopus 로고
    • Homogeneity and long-term stability of tetracycline-regulated gene expression with low basal activity by using the rtTA2S-M2 transactivator and insulator-flanked reporter vectors
    • Qu Z., Thottassery J.V., Van Ginkel S., et al. Homogeneity and long-term stability of tetracycline-regulated gene expression with low basal activity by using the rtTA2S-M2 transactivator and insulator-flanked reporter vectors. Gene 327 (2004) 61-73
    • (2004) Gene , vol.327 , pp. 61-73
    • Qu, Z.1    Thottassery, J.V.2    Van Ginkel, S.3
  • 20
    • 0036426634 scopus 로고    scopus 로고
    • Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling
    • Zhu Z., Zheng T., Lee C.G., Homer R.J., and Elias J.A. Tetracycline-controlled transcriptional regulation systems: advances and application in transgenic animal modeling. Semin Cell Dev Biol 13 (2002) 121-128
    • (2002) Semin Cell Dev Biol , vol.13 , pp. 121-128
    • Zhu, Z.1    Zheng, T.2    Lee, C.G.3    Homer, R.J.4    Elias, J.A.5
  • 21
    • 0028795108 scopus 로고
    • Efficacy of tetracycline-controlled gene expression is influenced by cell type
    • Ackland-Berglund C.E., and Leib D.A. Efficacy of tetracycline-controlled gene expression is influenced by cell type. Biotechniques 18 (1995) 196-200
    • (1995) Biotechniques , vol.18 , pp. 196-200
    • Ackland-Berglund, C.E.1    Leib, D.A.2
  • 22
    • 31944449735 scopus 로고    scopus 로고
    • AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis
    • Wang X., Bolotin D., Chu D.H., Polak L., Williams T., and Fuchs E. AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis. J Cell Biol 172 (2006) 409-421
    • (2006) J Cell Biol , vol.172 , pp. 409-421
    • Wang, X.1    Bolotin, D.2    Chu, D.H.3    Polak, L.4    Williams, T.5    Fuchs, E.6
  • 23
    • 2442694178 scopus 로고    scopus 로고
    • Transcription factor AP-2alpha triggers apoptosis in cardiac myocytes
    • Muller F.U., Loser K., Kleideiter U., et al. Transcription factor AP-2alpha triggers apoptosis in cardiac myocytes. Cell Death Differ 11 (2004) 485-493
    • (2004) Cell Death Differ , vol.11 , pp. 485-493
    • Muller, F.U.1    Loser, K.2    Kleideiter, U.3
  • 24
    • 33646420465 scopus 로고    scopus 로고
    • Defining the regulatory elements in the proximal promoter of DeltaNp63 in keratinocytes: Potential roles for Sp1/Sp3, NF-Y, and p63
    • Romano R.A., Birkaya B., and Sinha S. Defining the regulatory elements in the proximal promoter of DeltaNp63 in keratinocytes: Potential roles for Sp1/Sp3, NF-Y, and p63. J Invest Dermatol 126 (2006) 1469-1479
    • (2006) J Invest Dermatol , vol.126 , pp. 1469-1479
    • Romano, R.A.1    Birkaya, B.2    Sinha, S.3
  • 25
    • 0022977978 scopus 로고
    • Powerful and versatile enhancer-promoter unit for mammalian expression vectors
    • Foecking M.K., and Hofstetter H. Powerful and versatile enhancer-promoter unit for mammalian expression vectors. Gene 45 (1986) 101-105
    • (1986) Gene , vol.45 , pp. 101-105
    • Foecking, M.K.1    Hofstetter, H.2
  • 26
    • 0033571986 scopus 로고    scopus 로고
    • Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: a study using the tetracycline-inducible system in human cancer cells
    • Gopalkrishnan R.V., Christiansen K.A., Goldstein N.I., DePinho R.A., and Fisher P.B. Use of the human EF-1alpha promoter for expression can significantly increase success in establishing stable cell lines with consistent expression: a study using the tetracycline-inducible system in human cancer cells. Nucleic Acids Res 27 (1999) 4775-4782
    • (1999) Nucleic Acids Res , vol.27 , pp. 4775-4782
    • Gopalkrishnan, R.V.1    Christiansen, K.A.2    Goldstein, N.I.3    DePinho, R.A.4    Fisher, P.B.5
  • 27
    • 0036871275 scopus 로고    scopus 로고
    • Comparison of the EF-1 alpha and the CMV promoter for engineering stable tumor cell lines using recombinant adeno-associated virus
    • Teschendorf C., Warrington Jr. K.H., Siemann D.W., and Muzyczka N. Comparison of the EF-1 alpha and the CMV promoter for engineering stable tumor cell lines using recombinant adeno-associated virus. Anticancer Res 22 (2002) 3325-3330
    • (2002) Anticancer Res , vol.22 , pp. 3325-3330
    • Teschendorf, C.1    Warrington Jr., K.H.2    Siemann, D.W.3    Muzyczka, N.4
  • 28
    • 24944522678 scopus 로고    scopus 로고
    • Construction and characterization of multiple human colon cancer cell lines for inducibly regulated gene expression
    • Welman A., Cawthorne C., Barraclough J., et al. Construction and characterization of multiple human colon cancer cell lines for inducibly regulated gene expression. J Cell Biochem 94 (2005) 1148-1162
    • (2005) J Cell Biochem , vol.94 , pp. 1148-1162
    • Welman, A.1    Cawthorne, C.2    Barraclough, J.3
  • 29
    • 0022885466 scopus 로고
    • Activating elements in the promoter region of the chicken beta-actin gene
    • Fregien N., and Davidson N. Activating elements in the promoter region of the chicken beta-actin gene. Gene 48 (1986) 1-11
    • (1986) Gene , vol.48 , pp. 1-11
    • Fregien, N.1    Davidson, N.2
  • 31
    • 13144275262 scopus 로고    scopus 로고
    • Conditional lineage ablation to model human diseases
    • Lee P., Morley G., Huang Q., et al. Conditional lineage ablation to model human diseases. Proc Natl Acad Sci USA 95 (1998) 11371-11376
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 11371-11376
    • Lee, P.1    Morley, G.2    Huang, Q.3
  • 32
    • 0034736585 scopus 로고    scopus 로고
    • Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control
    • Hilger-Eversheim K., Moser M., Schorle H., and Buettner R. Regulatory roles of AP-2 transcription factors in vertebrate development, apoptosis and cell-cycle control. Gene 260 (2000) 1-12
    • (2000) Gene , vol.260 , pp. 1-12
    • Hilger-Eversheim, K.1    Moser, M.2    Schorle, H.3    Buettner, R.4
  • 33
    • 0034103619 scopus 로고    scopus 로고
    • Defining the regulatory factors required for epidermal gene expression
    • Sinha S., Degenstein L., Copenhaver C., and Fuchs E. Defining the regulatory factors required for epidermal gene expression. Mol Cell Biol 20 (2000) 2543-2555
    • (2000) Mol Cell Biol , vol.20 , pp. 2543-2555
    • Sinha, S.1    Degenstein, L.2    Copenhaver, C.3    Fuchs, E.4
  • 34
    • 0346101795 scopus 로고    scopus 로고
    • Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition
    • Wajapeyee N., and Somasundaram K. Cell cycle arrest and apoptosis induction by activator protein 2alpha (AP-2alpha) and the role of p53 and p21WAF1/CIP1 in AP-2alpha-mediated growth inhibition. J Biol Chem 278 (2003) 52093-52101
    • (2003) J Biol Chem , vol.278 , pp. 52093-52101
    • Wajapeyee, N.1    Somasundaram, K.2
  • 35
    • 33745203742 scopus 로고    scopus 로고
    • Apoptosis induction by activator protein 2alpha involves transcriptional repression of Bcl-2
    • Wajapeyee N., Britto R., Ravishankar H.M., and Somasundaram K. Apoptosis induction by activator protein 2alpha involves transcriptional repression of Bcl-2. J Biol Chem 281 (2006) 16207-16219
    • (2006) J Biol Chem , vol.281 , pp. 16207-16219
    • Wajapeyee, N.1    Britto, R.2    Ravishankar, H.M.3    Somasundaram, K.4
  • 36
    • 0028410565 scopus 로고
    • A chimeric transactivator allows tetracycline-responsive gene expression in whole plants
    • Weinmann P., Gossen M., Hillen W., Bujard H., and Gatz C. A chimeric transactivator allows tetracycline-responsive gene expression in whole plants. Plant J 5 (1994) 559-569
    • (1994) Plant J , vol.5 , pp. 559-569
    • Weinmann, P.1    Gossen, M.2    Hillen, W.3    Bujard, H.4    Gatz, C.5
  • 37
    • 0033731551 scopus 로고    scopus 로고
    • Conditional gene expression in the epidermis of transgenic mice using the tetracycline-regulated transactivators tTA and rTA linked to the keratin 5 promoter
    • Diamond I., Owolabi T., Marco M., Lam C., and Glick A. Conditional gene expression in the epidermis of transgenic mice using the tetracycline-regulated transactivators tTA and rTA linked to the keratin 5 promoter. J Invest Dermatol 115 (2000) 788-794
    • (2000) J Invest Dermatol , vol.115 , pp. 788-794
    • Diamond, I.1    Owolabi, T.2    Marco, M.3    Lam, C.4    Glick, A.5
  • 38
    • 0033578067 scopus 로고    scopus 로고
    • Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice
    • Xie W., Chow L.T., Paterson A.J., Chin E., and Kudlow J.E. Conditional expression of the ErbB2 oncogene elicits reversible hyperplasia in stratified epithelia and up-regulation of TGFalpha expression in transgenic mice. Oncogene 18 (1999) 3593-3607
    • (1999) Oncogene , vol.18 , pp. 3593-3607
    • Xie, W.1    Chow, L.T.2    Paterson, A.J.3    Chin, E.4    Kudlow, J.E.5
  • 39
    • 0025041030 scopus 로고
    • Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter
    • Bailleul B., Surani M.A., White S., et al. Skin hyperkeratosis and papilloma formation in transgenic mice expressing a ras oncogene from a suprabasal keratin promoter. Cell 62 (1990) 697-708
    • (1990) Cell , vol.62 , pp. 697-708
    • Bailleul, B.1    Surani, M.A.2    White, S.3
  • 40
    • 3242671305 scopus 로고    scopus 로고
    • Tetracycline-regulated transactivators driven by the involucrin promoter to achieve epidermal conditional gene expression
    • Jaubert J., Patel S., Cheng J., and Segre J.A. Tetracycline-regulated transactivators driven by the involucrin promoter to achieve epidermal conditional gene expression. J Invest Dermatol 123 (2004) 313-318
    • (2004) J Invest Dermatol , vol.123 , pp. 313-318
    • Jaubert, J.1    Patel, S.2    Cheng, J.3    Segre, J.A.4
  • 41
    • 20444424942 scopus 로고    scopus 로고
    • Genome-wide screening for gene function using RNAi in mammalian cells
    • Cullen L.M., and Arndt G.M. Genome-wide screening for gene function using RNAi in mammalian cells. Immunol Cell Biol 83 (2005) 217-223
    • (2005) Immunol Cell Biol , vol.83 , pp. 217-223
    • Cullen, L.M.1    Arndt, G.M.2
  • 42
    • 33847793202 scopus 로고    scopus 로고
    • Gene silencing by small regulatory RNAs in mammalian cells
    • Scherr M., and Eder M. Gene silencing by small regulatory RNAs in mammalian cells. Cell Cycle 6 (2007) 444-449
    • (2007) Cell Cycle , vol.6 , pp. 444-449
    • Scherr, M.1    Eder, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.