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Volumn 31, Issue 1, 2008, Pages 12-20

Macrolides beyond the conventional antimicrobials: a class of potent immunomodulators

Author keywords

Bronchial asthma; Cystic fibrosis; Diffuse panbronchiolitis; Inflammation; Macrolides; Sepsis

Indexed keywords

AMIKACIN; AMOXICILLIN; AZITHROMYCIN; CLARITHROMYCIN; CYTOKINE; ERYTHROMYCIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTONE; LEVOFLOXACIN; MACROLIDE; MIDECAMYCIN; PLACEBO; SODIUM CHLORIDE; TELITHROMYCIN;

EID: 36849073243     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2007.08.001     Document Type: Short Survey
Times cited : (169)

References (75)
  • 1
    • 1042288092 scopus 로고    scopus 로고
    • Immunomodulatory activity and effectiveness of macrolides in chronic airway disease
    • Rubin B.K., and Henke M.O. Immunomodulatory activity and effectiveness of macrolides in chronic airway disease. Chest 125 Suppl. 2 (2004) 70-78
    • (2004) Chest , vol.125 , Issue.SUPPL. 2 , pp. 70-78
    • Rubin, B.K.1    Henke, M.O.2
  • 2
    • 11144243103 scopus 로고    scopus 로고
    • Non-antimicrobial effects of antibacterial agents
    • Pasquale T.R., and Tan J.S. Non-antimicrobial effects of antibacterial agents. Clin Infect Dis 40 (2005) 127-135
    • (2005) Clin Infect Dis , vol.40 , pp. 127-135
    • Pasquale, T.R.1    Tan, J.S.2
  • 3
    • 0037442372 scopus 로고    scopus 로고
    • Addition of a macrolide to a β-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia
    • Martίnez J.A., Horcajada J.P., Almela M., et al. Addition of a macrolide to a β-lactam-based empirical antibiotic regimen is associated with lower in-hospital mortality for patients with bacteremic pneumococcal pneumonia. Clin Infect Dis 36 (2003) 389-395
    • (2003) Clin Infect Dis , vol.36 , pp. 389-395
    • Martnez, J.A.1    Horcajada, J.P.2    Almela, M.3
  • 4
    • 17744376776 scopus 로고    scopus 로고
    • Lower mortality among patients with community-acquired pneumonia treated with a macrolide plus a beta-lactam agent versus a beta-lactam agent alone
    • Vázquez E.G., Mensa J., Martίnez J.A., et al. Lower mortality among patients with community-acquired pneumonia treated with a macrolide plus a beta-lactam agent versus a beta-lactam agent alone. Eur J Clin Microbiol Infect Dis 24 (2005) 190-195
    • (2005) Eur J Clin Microbiol Infect Dis , vol.24 , pp. 190-195
    • Vázquez, E.G.1    Mensa, J.2    Martnez, J.A.3
  • 5
    • 0033591467 scopus 로고    scopus 로고
    • Bacterial biofilms: a common cause of persistent infections
    • Costerton J.W., Stewart P.S., and Greenberg E.P. Bacterial biofilms: a common cause of persistent infections. Science 284 (1999) 1318-1322
    • (1999) Science , vol.284 , pp. 1318-1322
    • Costerton, J.W.1    Stewart, P.S.2    Greenberg, E.P.3
  • 7
    • 0037532479 scopus 로고    scopus 로고
    • Quorum sensing and its relevance to infectious diseases
    • Donabedian H. Quorum sensing and its relevance to infectious diseases. J Infect 46 (2003) 207-214
    • (2003) J Infect , vol.46 , pp. 207-214
    • Donabedian, H.1
  • 8
    • 0348230962 scopus 로고    scopus 로고
    • Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections
    • Hentzer M., and Givskov M. Pharmacological inhibition of quorum sensing for the treatment of chronic bacterial infections. J Clin Invest 112 (2003) 1300-1307
    • (2003) J Clin Invest , vol.112 , pp. 1300-1307
    • Hentzer, M.1    Givskov, M.2
  • 9
    • 1042265016 scopus 로고    scopus 로고
    • Effects of subinhibitory concentrations of macrolide antibiotics on Pseudomonas aeruginosa
    • Wozniak D.J., and Keyser R. Effects of subinhibitory concentrations of macrolide antibiotics on Pseudomonas aeruginosa. Chest 125 Suppl. 2 (2004) 62-69
    • (2004) Chest , vol.125 , Issue.SUPPL. 2 , pp. 62-69
    • Wozniak, D.J.1    Keyser, R.2
  • 10
    • 10844296436 scopus 로고    scopus 로고
    • Azithromycin retards Pseudomonas aeruginosa biofilm formation
    • Gillis R.J., and Iglewski B.H. Azithromycin retards Pseudomonas aeruginosa biofilm formation. J Clin Microbiol 42 (2004) 5842-5845
    • (2004) J Clin Microbiol , vol.42 , pp. 5842-5845
    • Gillis, R.J.1    Iglewski, B.H.2
  • 11
    • 33646452555 scopus 로고    scopus 로고
    • Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa PA01: a global approach
    • Nalca Y., Jänsch L., Bredenbruch F., Geffers R., Buer J., and Häussler S. Quorum-sensing antagonistic activities of azithromycin in Pseudomonas aeruginosa PA01: a global approach. Antimicrob Agents Chemother 50 (2006) 1680-1688
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1680-1688
    • Nalca, Y.1    Jänsch, L.2    Bredenbruch, F.3    Geffers, R.4    Buer, J.5    Häussler, S.6
  • 13
    • 0036001192 scopus 로고    scopus 로고
    • Effect of clarithromycin on chronic respiratory infection caused by Pseudomonas aeruginosa with biofilm formation in an experimental murine model
    • Yanagihara K., Tomono K., Imamura Y., et al. Effect of clarithromycin on chronic respiratory infection caused by Pseudomonas aeruginosa with biofilm formation in an experimental murine model. J Antimicrob Chemother 49 (2002) 867-870
    • (2002) J Antimicrob Chemother , vol.49 , pp. 867-870
    • Yanagihara, K.1    Tomono, K.2    Imamura, Y.3
  • 14
    • 0033939627 scopus 로고    scopus 로고
    • Combination therapy for chronic Pseudomonas aeruginosa respiratory infection associated with biofilm formation
    • Yanagihara K., Tomono K., Sawai T., et al. Combination therapy for chronic Pseudomonas aeruginosa respiratory infection associated with biofilm formation. J Antimicrob Chemother 46 (2000) 69-72
    • (2000) J Antimicrob Chemother , vol.46 , pp. 69-72
    • Yanagihara, K.1    Tomono, K.2    Sawai, T.3
  • 15
    • 0042810728 scopus 로고    scopus 로고
    • Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis
    • Liaudet L., Szabo C., Evgenov O.V., et al. Flagellin from gram-negative bacteria is a potent mediator of acute pulmonary inflammation in sepsis. Shock 19 (2003) 131-137
    • (2003) Shock , vol.19 , pp. 131-137
    • Liaudet, L.1    Szabo, C.2    Evgenov, O.V.3
  • 16
    • 34447565004 scopus 로고    scopus 로고
    • Clarithromycin has an immunomodulatory effect on ERK-mediated inflammation induced by Pseudomonas aeruginosa flagellin
    • Shinkai M., López-Boado Y.S., and Rubin B.K. Clarithromycin has an immunomodulatory effect on ERK-mediated inflammation induced by Pseudomonas aeruginosa flagellin. J Antimicrob Chemother 59 (2007) 1096-1101
    • (2007) J Antimicrob Chemother , vol.59 , pp. 1096-1101
    • Shinkai, M.1    López-Boado, Y.S.2    Rubin, B.K.3
  • 17
    • 33644791106 scopus 로고    scopus 로고
    • Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells
    • Shinkai M., Foster G.H., and Rubin B.K. Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 290 (2006) L75-L85
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.290
    • Shinkai, M.1    Foster, G.H.2    Rubin, B.K.3
  • 18
    • 33646444723 scopus 로고    scopus 로고
    • Clarithromycin delays progression of bronchial epithelial cells from G1 phase to S phase and delays cell growth via extracellular signal-regulated protein kinase suppression
    • Shinkai M., Tamaoki J., Kobayashi H., et al. Clarithromycin delays progression of bronchial epithelial cells from G1 phase to S phase and delays cell growth via extracellular signal-regulated protein kinase suppression. Antimicrob Agents Chemother 50 (2006) 1738-1744
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 1738-1744
    • Shinkai, M.1    Tamaoki, J.2    Kobayashi, H.3
  • 20
    • 1942454728 scopus 로고    scopus 로고
    • Effect of multiple doses of clarithromycin and amoxicillin on IL-6, IFNγ and IL-10 plasma levels in patients with community acquired pneumonia
    • Demarini G., Esposti D., Marthyn P., Lapidari A., Fraschini F., and Scaglione F. Effect of multiple doses of clarithromycin and amoxicillin on IL-6, IFNγ and IL-10 plasma levels in patients with community acquired pneumonia. J Chemother 16 (2004) 82-85
    • (2004) J Chemother , vol.16 , pp. 82-85
    • Demarini, G.1    Esposti, D.2    Marthyn, P.3    Lapidari, A.4    Fraschini, F.5    Scaglione, F.6
  • 21
    • 0842307140 scopus 로고    scopus 로고
    • Immunomodulating effect of antimicrobial agents on cytokine production by human polymorphonuclear neutrophils
    • Reato G., Cuffini A.M., and Tullio V. Immunomodulating effect of antimicrobial agents on cytokine production by human polymorphonuclear neutrophils. Int J Antimicrob Agents 23 (2004) 150-154
    • (2004) Int J Antimicrob Agents , vol.23 , pp. 150-154
    • Reato, G.1    Cuffini, A.M.2    Tullio, V.3
  • 22
    • 0036001168 scopus 로고    scopus 로고
    • Clarithromycin suppresses lipopolysaccharide-induced interleukin-8 production by human monocytes through AP-1 and NF-κB transcription factors
    • Kikuchi T., Hagiwara K., Honda Y., et al. Clarithromycin suppresses lipopolysaccharide-induced interleukin-8 production by human monocytes through AP-1 and NF-κB transcription factors. J Antimicrob Chemother 49 (2002) 745-755
    • (2002) J Antimicrob Chemother , vol.49 , pp. 745-755
    • Kikuchi, T.1    Hagiwara, K.2    Honda, Y.3
  • 23
    • 33847648430 scopus 로고    scopus 로고
    • Macrolide antibiotics promote the LPS-induced upregulation of prostaglandin E receptor EP2 and thus attenuate macrolide suppression of IL-6 production
    • Sato Y., Kaneko K., and Inoue M. Macrolide antibiotics promote the LPS-induced upregulation of prostaglandin E receptor EP2 and thus attenuate macrolide suppression of IL-6 production. Prostaglandins Leukot Essent Fatty Acids 76 (2007) 181-188
    • (2007) Prostaglandins Leukot Essent Fatty Acids , vol.76 , pp. 181-188
    • Sato, Y.1    Kaneko, K.2    Inoue, M.3
  • 24
    • 26044450582 scopus 로고    scopus 로고
    • Effects of clarithromycin on inflammatory cell mediator release and survival
    • Borszcz P.D., Befus D., Moqbel R., et al. Effects of clarithromycin on inflammatory cell mediator release and survival. Chemotherapy 51 (2005) 206-210
    • (2005) Chemotherapy , vol.51 , pp. 206-210
    • Borszcz, P.D.1    Befus, D.2    Moqbel, R.3
  • 25
    • 0037224290 scopus 로고    scopus 로고
    • Fourteen-member macrolides promote the phosphatidylserine receptor-dependent phagocytosis of apoptotic neutrophils by alveolar macrophages
    • Yamaryo T., Oishi K., Yoshimine H., Tsuchihashi Y., Matsushima K., and Nagatake T. Fourteen-member macrolides promote the phosphatidylserine receptor-dependent phagocytosis of apoptotic neutrophils by alveolar macrophages. Antimicrob Agents Chemother 47 (2003) 48-53
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 48-53
    • Yamaryo, T.1    Oishi, K.2    Yoshimine, H.3    Tsuchihashi, Y.4    Matsushima, K.5    Nagatake, T.6
  • 26
    • 33751296731 scopus 로고    scopus 로고
    • Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages
    • Hodge S., Hodge G., Brozyna S., Jersmann H., Holmes M., and Reynolds P.N. Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages. Eur Respir J 28 (2006) 486-495
    • (2006) Eur Respir J , vol.28 , pp. 486-495
    • Hodge, S.1    Hodge, G.2    Brozyna, S.3    Jersmann, H.4    Holmes, M.5    Reynolds, P.N.6
  • 27
    • 33846837316 scopus 로고    scopus 로고
    • Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells
    • Sugiyama K., Shirai R., Mukae H., et al. Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells. Clin Exp Immunol 147 (2007) 540-546
    • (2007) Clin Exp Immunol , vol.147 , pp. 540-546
    • Sugiyama, K.1    Shirai, R.2    Mukae, H.3
  • 28
    • 24644439165 scopus 로고    scopus 로고
    • Differential effects of three antibiotics on T helper cell cytokine expression
    • Williams A.C., Galley H.F., Watt A.M., and Webster N.R. Differential effects of three antibiotics on T helper cell cytokine expression. J Antimicrob Chemother 56 (2005) 502-506
    • (2005) J Antimicrob Chemother , vol.56 , pp. 502-506
    • Williams, A.C.1    Galley, H.F.2    Watt, A.M.3    Webster, N.R.4
  • 29
    • 0041854646 scopus 로고    scopus 로고
    • Clarithromycin extended-release tablet: a review of its use in the management of respiratory tract infections
    • Darkes M.J., and Perry C.M. Clarithromycin extended-release tablet: a review of its use in the management of respiratory tract infections. Am J Respir Med 2 (2003) 175-201
    • (2003) Am J Respir Med , vol.2 , pp. 175-201
    • Darkes, M.J.1    Perry, C.M.2
  • 30
    • 29444440569 scopus 로고    scopus 로고
    • Clarithromycin extended-release in community-acquired respiratory tract infections
    • Williams K.N., and Bishai W.R. Clarithromycin extended-release in community-acquired respiratory tract infections. Expert Opin Pharmacother 6 (2005) 2867-2876
    • (2005) Expert Opin Pharmacother , vol.6 , pp. 2867-2876
    • Williams, K.N.1    Bishai, W.R.2
  • 32
    • 0242432501 scopus 로고    scopus 로고
    • Comparative distribution of azithromycin in lung tissue of patients given oral daily doses of 500 and 1000 mg
    • Danesi R., Lupetti A., and Barbara C. Comparative distribution of azithromycin in lung tissue of patients given oral daily doses of 500 and 1000 mg. J Antimicrob Chemother 51 (2003) 939-945
    • (2003) J Antimicrob Chemother , vol.51 , pp. 939-945
    • Danesi, R.1    Lupetti, A.2    Barbara, C.3
  • 33
    • 4243126943 scopus 로고    scopus 로고
    • Low-dose, long-term macrolide therapy in asthma: an overview
    • Hatipoglu U., and Rubinstein I. Low-dose, long-term macrolide therapy in asthma: an overview. Clin Mol Allergy 2 (2004) 4
    • (2004) Clin Mol Allergy , vol.2 , pp. 4
    • Hatipoglu, U.1    Rubinstein, I.2
  • 35
    • 0034544739 scopus 로고    scopus 로고
    • Long-term clarithromycin decreases prednisone requirements in elderly patients with prednisone-dependent asthma
    • Garey K.W., Rubinstein I., Gotfried M.H., Khan I.J., Varma S., and Danziger L.H. Long-term clarithromycin decreases prednisone requirements in elderly patients with prednisone-dependent asthma. Chest 118 (2000) 1826-1827
    • (2000) Chest , vol.118 , pp. 1826-1827
    • Garey, K.W.1    Rubinstein, I.2    Gotfried, M.H.3    Khan, I.J.4    Varma, S.5    Danziger, L.H.6
  • 36
    • 1042299785 scopus 로고    scopus 로고
    • Macrolides for the treatment of chronic sinusitis, asthma, and COPD
    • Gotfried M.H. Macrolides for the treatment of chronic sinusitis, asthma, and COPD. Chest 125 Suppl. 2 (2004) 52-61
    • (2004) Chest , vol.125 , Issue.SUPPL. 2 , pp. 52-61
    • Gotfried, M.H.1
  • 37
    • 0036279989 scopus 로고    scopus 로고
    • Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin
    • Kraft M., Cassell G.H., Pak J., et al. Mycoplasma pneumoniae and Chlamydia pneumoniae in asthma: effect of clarithromycin. Chest 121 (2002) 1782-1788
    • (2002) Chest , vol.121 , pp. 1782-1788
    • Kraft, M.1    Cassell, G.H.2    Pak, J.3
  • 38
    • 2442453846 scopus 로고    scopus 로고
    • Clarithromycin reduces the severity of bronchial hyperresponsiveness in patients with asthma
    • Kostadima E., Tsiodras S., Alexopoulos E.I., et al. Clarithromycin reduces the severity of bronchial hyperresponsiveness in patients with asthma. Eur Respir J 23 (2004) 714-717
    • (2004) Eur Respir J , vol.23 , pp. 714-717
    • Kostadima, E.1    Tsiodras, S.2    Alexopoulos, E.I.3
  • 39
    • 34248399202 scopus 로고    scopus 로고
    • Azithromycin reduces bronchial hyperresponsiveness and neutrophilic airway inflammation in asthmatic children: a preliminary report
    • Piacentini G.L., Peroni D.G., Bodini A., et al. Azithromycin reduces bronchial hyperresponsiveness and neutrophilic airway inflammation in asthmatic children: a preliminary report. Allergy Asthma Proc 28 (2007) 194-198
    • (2007) Allergy Asthma Proc , vol.28 , pp. 194-198
    • Piacentini, G.L.1    Peroni, D.G.2    Bodini, A.3
  • 40
    • 33645791946 scopus 로고    scopus 로고
    • The effect of telithromycin in acute exacerbations of asthma
    • Johnston S.L., Blasi F., Black P.N., et al. The effect of telithromycin in acute exacerbations of asthma. N Engl J Med 354 (2006) 1589-1600
    • (2006) N Engl J Med , vol.354 , pp. 1589-1600
    • Johnston, S.L.1    Blasi, F.2    Black, P.N.3
  • 41
    • 0036168753 scopus 로고    scopus 로고
    • New antimicrobials in the management of cystic fibrosis
    • Hoiby N. New antimicrobials in the management of cystic fibrosis. J Antimicrob Chemother 49 (2002) 235-238
    • (2002) J Antimicrob Chemother , vol.49 , pp. 235-238
    • Hoiby, N.1
  • 42
    • 8644251326 scopus 로고    scopus 로고
    • Azithromycin in cystic fibrosis
    • Southern K.W., and Barker P.M. Azithromycin in cystic fibrosis. Eur Respir J 24 (2004) 834-838
    • (2004) Eur Respir J , vol.24 , pp. 834-838
    • Southern, K.W.1    Barker, P.M.2
  • 43
    • 0036185807 scopus 로고    scopus 로고
    • Effect of long term treatment with azithromycin on disease parameters in cystic fibrosis: a randomised trial
    • Wolter J., Seeney S., Bell S., Bowler S., Masel P., and McCormack J. Effect of long term treatment with azithromycin on disease parameters in cystic fibrosis: a randomised trial. Thorax 57 (2002) 212-216
    • (2002) Thorax , vol.57 , pp. 212-216
    • Wolter, J.1    Seeney, S.2    Bell, S.3    Bowler, S.4    Masel, P.5    McCormack, J.6
  • 44
    • 0037190575 scopus 로고    scopus 로고
    • Long term azithromycin in children with cystic fibrosis: a randomized, placebo-controlled crossover trial
    • Equi A., Balfour-Lynn I.M., Bush A., and Rosenthal M. Long term azithromycin in children with cystic fibrosis: a randomized, placebo-controlled crossover trial. Lancet 360 (2002) 978-984
    • (2002) Lancet , vol.360 , pp. 978-984
    • Equi, A.1    Balfour-Lynn, I.M.2    Bush, A.3    Rosenthal, M.4
  • 45
    • 0141816759 scopus 로고    scopus 로고
    • Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial
    • Saiman L., Marshall B.C., Mayer-Hamblett N., et al. Azithromycin in patients with cystic fibrosis chronically infected with Pseudomonas aeruginosa: a randomized controlled trial. JAMA 290 (2003) 1749-1756
    • (2003) JAMA , vol.290 , pp. 1749-1756
    • Saiman, L.1    Marshall, B.C.2    Mayer-Hamblett, N.3
  • 46
    • 33749984264 scopus 로고    scopus 로고
    • Long term effects of azithromycin in patients with cystic fibrosis: a double blind, placebo controlled trial
    • Clement A., Tamalet A., Leroux E., Ravilly S., Fauroux B., and Jais J.P. Long term effects of azithromycin in patients with cystic fibrosis: a double blind, placebo controlled trial. Thorax 61 (2006) 895-902
    • (2006) Thorax , vol.61 , pp. 895-902
    • Clement, A.1    Tamalet, A.2    Leroux, E.3    Ravilly, S.4    Fauroux, B.5    Jais, J.P.6
  • 47
    • 4544281523 scopus 로고    scopus 로고
    • Effect of subinhibitory concentrations of azithromycin on adherence of Pseudomonas aeruginosa to bronchial mucins collected from cystic fibrosis patients
    • Carfartan G., Gerardin P., Turck D., and Husson M.O. Effect of subinhibitory concentrations of azithromycin on adherence of Pseudomonas aeruginosa to bronchial mucins collected from cystic fibrosis patients. J Antimicrob Chemother 53 (2004) 686-688
    • (2004) J Antimicrob Chemother , vol.53 , pp. 686-688
    • Carfartan, G.1    Gerardin, P.2    Turck, D.3    Husson, M.O.4
  • 48
    • 34249864455 scopus 로고    scopus 로고
    • Clinical response to azithromycin in cystic fibrosis correlates with in vitro effects on Pseudomonas aeruginosa phenotypes
    • Nguyen D., Emond M.J., Mayer-Hamblett N., Saiman L., Marshall B.C., and Burns J.L. Clinical response to azithromycin in cystic fibrosis correlates with in vitro effects on Pseudomonas aeruginosa phenotypes. Pediatr Pulmonol 42 (2007) 533-541
    • (2007) Pediatr Pulmonol , vol.42 , pp. 533-541
    • Nguyen, D.1    Emond, M.J.2    Mayer-Hamblett, N.3    Saiman, L.4    Marshall, B.C.5    Burns, J.L.6
  • 49
    • 33344461148 scopus 로고    scopus 로고
    • Exploring the mechanisms of macrolides in cystic fibrosis
    • Equi A.C., Davies J.C., Painter H., et al. Exploring the mechanisms of macrolides in cystic fibrosis. Respir Med 100 (2006) 687-697
    • (2006) Respir Med , vol.100 , pp. 687-697
    • Equi, A.C.1    Davies, J.C.2    Painter, H.3
  • 50
    • 17644368856 scopus 로고    scopus 로고
    • Effect of macrolides on in vivo iron transport across cystic fibrosis nasal epithelium
    • Barker P.M., Gillie D.J., Schechter M.S., and Rubin B.K. Effect of macrolides on in vivo iron transport across cystic fibrosis nasal epithelium. Am J Respir Crit Care Med 171 (2005) 868-871
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 868-871
    • Barker, P.M.1    Gillie, D.J.2    Schechter, M.S.3    Rubin, B.K.4
  • 52
    • 33750078400 scopus 로고    scopus 로고
    • Anti-inflammatory effects of azithromycin in cystic fibrosis airway epithelial cells
    • Cigana C., Nicolis E., Pasetto M., Assael B.M., and Melotti P. Anti-inflammatory effects of azithromycin in cystic fibrosis airway epithelial cells. Biochem Biophys Res Commun 350 (2006) 977-982
    • (2006) Biochem Biophys Res Commun , vol.350 , pp. 977-982
    • Cigana, C.1    Nicolis, E.2    Pasetto, M.3    Assael, B.M.4    Melotti, P.5
  • 53
    • 33847688940 scopus 로고    scopus 로고
    • Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells
    • Cigana C., Assael B.M., and Melotti P. Azithromycin selectively reduces tumor necrosis factor alpha levels in cystic fibrosis airway epithelial cells. Antimicrob Agents Chemother 51 (2007) 975-981
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 975-981
    • Cigana, C.1    Assael, B.M.2    Melotti, P.3
  • 54
    • 13244291394 scopus 로고    scopus 로고
    • Anti-inflammatory effects of macrolides-an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions?
    • Amsden G.W. Anti-inflammatory effects of macrolides-an underappreciated benefit in the treatment of community-acquired respiratory tract infections and chronic inflammatory pulmonary conditions?. J Antimicrob Chemother 55 (2005) 10-21
    • (2005) J Antimicrob Chemother , vol.55 , pp. 10-21
    • Amsden, G.W.1
  • 55
    • 3543117815 scopus 로고    scopus 로고
    • Macrolide activities beyond their antimicrobial effects: macrolides in diffuse panbronchiolitis and cystic fibrosis
    • Schultz M.J. Macrolide activities beyond their antimicrobial effects: macrolides in diffuse panbronchiolitis and cystic fibrosis. J Antimicrob Chemother 54 (2005) 21-28
    • (2005) J Antimicrob Chemother , vol.54 , pp. 21-28
    • Schultz, M.J.1
  • 56
    • 0038143318 scopus 로고    scopus 로고
    • Long-term efficacy and safety of clarithromycin treatment in patients with diffuse panbronchiolitis
    • Kadota J., Mukae H., Ishii H., et al. Long-term efficacy and safety of clarithromycin treatment in patients with diffuse panbronchiolitis. Respir Med 97 (2003) 844-850
    • (2003) Respir Med , vol.97 , pp. 844-850
    • Kadota, J.1    Mukae, H.2    Ishii, H.3
  • 57
    • 0141791342 scopus 로고    scopus 로고
    • Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis
    • Kaneko Y., Yanagihara K., Seki M., et al. Clarithromycin inhibits overproduction of muc5ac core protein in murine model of diffuse panbronchiolitis. Am J Physiol Lung Cell Mol Physiol 285 (2003) L847-L853
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.285
    • Kaneko, Y.1    Yanagihara, K.2    Seki, M.3
  • 58
    • 33748307448 scopus 로고    scopus 로고
    • Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome
    • Verleden G.M., Vanaudenaerde B.M., Dupont L.J., and van Raemdonck D.E. Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome. Am J Respir Crit Care Med 174 (2006) 566-570
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 566-570
    • Verleden, G.M.1    Vanaudenaerde, B.M.2    Dupont, L.J.3    van Raemdonck, D.E.4
  • 59
    • 28144460259 scopus 로고    scopus 로고
    • Macrolides. A treatment alternative for bronchiolitis obliterans organizing pneumonia?
    • Stover D.E., and Mangino D. Macrolides. A treatment alternative for bronchiolitis obliterans organizing pneumonia?. Chest 128 (2004) 3611-3617
    • (2004) Chest , vol.128 , pp. 3611-3617
    • Stover, D.E.1    Mangino, D.2
  • 60
    • 14844308020 scopus 로고    scopus 로고
    • Clinical implications of the immunomodulatory effects of macrolides
    • Tamaoki J., Kadota J., and Takizawa H. Clinical implications of the immunomodulatory effects of macrolides. Am J Med 117 (2004) 5S-11S
    • (2004) Am J Med , vol.117
    • Tamaoki, J.1    Kadota, J.2    Takizawa, H.3
  • 61
    • 0041874952 scopus 로고    scopus 로고
    • In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells
    • Shimizu T., Shimizu S., Hattori R., Gabazza E.C., and Majima Y. In vivo and in vitro effects of macrolide antibiotics on mucus secretion in airway epithelial cells. Am J Respir Crit Care Med 168 (2003) 581-587
    • (2003) Am J Respir Crit Care Med , vol.168 , pp. 581-587
    • Shimizu, T.1    Shimizu, S.2    Hattori, R.3    Gabazza, E.C.4    Majima, Y.5
  • 62
    • 21444449868 scopus 로고    scopus 로고
    • Modulation of neutrophil and inflammation markers in chronic obstructive pulmonary disease by short-term azithromycin treatment
    • Parnham M.J., Ćulić O., Eracović V., et al. Modulation of neutrophil and inflammation markers in chronic obstructive pulmonary disease by short-term azithromycin treatment. Eur J Pharmacol 517 (2005) 132-143
    • (2005) Eur J Pharmacol , vol.517 , pp. 132-143
    • Parnham, M.J.1    Ćulić, O.2    Eracović, V.3
  • 63
    • 4143127614 scopus 로고    scopus 로고
    • The effect of clarithromycin on inflammatory markers in chronic obstructive pulmonary disease: preliminary data
    • Basyigit I., Yidiz F., Ozkara S.K., Yildirim E., Boyaci H., and Ilgazli A. The effect of clarithromycin on inflammatory markers in chronic obstructive pulmonary disease: preliminary data. Ann Pharmacother 38 (2004) 1400-1405
    • (2004) Ann Pharmacother , vol.38 , pp. 1400-1405
    • Basyigit, I.1    Yidiz, F.2    Ozkara, S.K.3    Yildirim, E.4    Boyaci, H.5    Ilgazli, A.6
  • 64
    • 33645114890 scopus 로고    scopus 로고
    • Effects of clarithromycin on inflammatory parameters and clinical conditions in children with bronchiectasis
    • Yalçin E., Kiper N., O{combining double acute accent}zçelik U., et al. Effects of clarithromycin on inflammatory parameters and clinical conditions in children with bronchiectasis. J Clin Pharm Ther 31 (2006) 49-55
    • (2006) J Clin Pharm Ther , vol.31 , pp. 49-55
    • Yalçin, E.1    Kiper, N.2    Ozçelik, U.3
  • 65
    • 0347361713 scopus 로고    scopus 로고
    • Immunomodulatory clarithromycin treatment of experimental sepsis and acute pyelonephritis caused by multidrug-resistant Pseudomonas aeruginosa
    • Giamarellos-Bourboulis E.J., Adamis T., Laoutaris G., et al. Immunomodulatory clarithromycin treatment of experimental sepsis and acute pyelonephritis caused by multidrug-resistant Pseudomonas aeruginosa. Antimicrob Agents Chemother 48 (2004) 93-99
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 93-99
    • Giamarellos-Bourboulis, E.J.1    Adamis, T.2    Laoutaris, G.3
  • 66
    • 33644929201 scopus 로고    scopus 로고
    • Clarithromycin is an effective immunomodulator when administered late in experimental pyelonephritis by multidrug-resistant Pseudomonas aeruginosa
    • Giamarellos-Bourboulis E.J., Antonopoulou A., Raftogiannis M., et al. Clarithromycin is an effective immunomodulator when administered late in experimental pyelonephritis by multidrug-resistant Pseudomonas aeruginosa. BMC Infect Dis 6 (2006) 31
    • (2006) BMC Infect Dis , vol.6 , pp. 31
    • Giamarellos-Bourboulis, E.J.1    Antonopoulou, A.2    Raftogiannis, M.3
  • 67
    • 12344261855 scopus 로고    scopus 로고
    • Clarithromycin co-administered with amikacin attenuates systemic inflammation in experimental sepsis by Escherichia coli
    • Giamarellos-Bourboulis E.J., Baziaka F., Antonopoulou A., et al. Clarithromycin co-administered with amikacin attenuates systemic inflammation in experimental sepsis by Escherichia coli. Int J Antimicrob Agents 25 (2005) 168-172
    • (2005) Int J Antimicrob Agents , vol.25 , pp. 168-172
    • Giamarellos-Bourboulis, E.J.1    Baziaka, F.2    Antonopoulou, A.3
  • 68
    • 13644266012 scopus 로고    scopus 로고
    • Clarithromycin: immunomodulatory therapy of experimental sepsis and acute pyelonephritis by Escherichia coli
    • Giamarellos-Bourboulis E.J., Adamis T., Sabracos L., et al. Clarithromycin: immunomodulatory therapy of experimental sepsis and acute pyelonephritis by Escherichia coli. Scand J Infect Dis 37 (2005) 48-54
    • (2005) Scand J Infect Dis , vol.37 , pp. 48-54
    • Giamarellos-Bourboulis, E.J.1    Adamis, T.2    Sabracos, L.3
  • 69
    • 33645804394 scopus 로고    scopus 로고
    • Clarithromycin is an effective immunomodulator in experimental pyelonephritis caused by pan-resistant Klebsiella pneumoniae
    • Giamarellos-Bourboulis E.J., Tziortzioti V., Koutoukas P., et al. Clarithromycin is an effective immunomodulator in experimental pyelonephritis caused by pan-resistant Klebsiella pneumoniae. J Antimicrob Chemother 57 (2006) 937-944
    • (2006) J Antimicrob Chemother , vol.57 , pp. 937-944
    • Giamarellos-Bourboulis, E.J.1    Tziortzioti, V.2    Koutoukas, P.3
  • 70
    • 34250190652 scopus 로고    scopus 로고
    • Early apoptosis of blood monocytes is a determinant of survival in experimental sepsis by multi-drug-resistant Pseudomonas aeruginosa
    • Antonopoulou A., Raftogiannis M., Giamarellos-Bourboulis E.J., et al. Early apoptosis of blood monocytes is a determinant of survival in experimental sepsis by multi-drug-resistant Pseudomonas aeruginosa. Clin Exp Immunol 149 (2007) 103-108
    • (2007) Clin Exp Immunol , vol.149 , pp. 103-108
    • Antonopoulou, A.1    Raftogiannis, M.2    Giamarellos-Bourboulis, E.J.3
  • 71
    • 33747057193 scopus 로고    scopus 로고
    • Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice
    • Tkalčević V.I., Bošnjak B., Hračić B., et al. Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice. Eur J Pharmacol 539 (2006) 131-138
    • (2006) Eur J Pharmacol , vol.539 , pp. 131-138
    • Tkalčević, V.I.1    Bošnjak, B.2    Hračić, B.3
  • 72
    • 33846245519 scopus 로고    scopus 로고
    • Clarithromycin in the treatment of RSV bronchiolitis: a double-blind, randomized, placebo-controlled trial
    • Tahan F., Ozcan A., and Koc N. Clarithromycin in the treatment of RSV bronchiolitis: a double-blind, randomized, placebo-controlled trial. Eur Respir J 29 (2007) 91-97
    • (2007) Eur Respir J , vol.29 , pp. 91-97
    • Tahan, F.1    Ozcan, A.2    Koc, N.3
  • 73
    • 33846817134 scopus 로고    scopus 로고
    • Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study
    • Malhotra-Kumar S., Lammens C., Coenen S., van Herck K., and Goossens H. Effect of azithromycin and clarithromycin therapy on pharyngeal carriage of macrolide-resistant streptococci in healthy volunteers: a randomised, double-blind, placebo-controlled study. Lancet 369 (2007) 482-490
    • (2007) Lancet , vol.369 , pp. 482-490
    • Malhotra-Kumar, S.1    Lammens, C.2    Coenen, S.3    van Herck, K.4    Goossens, H.5
  • 74
    • 33845975311 scopus 로고    scopus 로고
    • Maintenance azithromycin treatment in pediatric patients with cystic fibrosis: long-term outcomes related to macrolide resistance and pulmonary function
    • Tramper-Stranders G.A., Wolfs T.F., Fleer A., Kimpen J.L., and van der Ent C.K. Maintenance azithromycin treatment in pediatric patients with cystic fibrosis: long-term outcomes related to macrolide resistance and pulmonary function. Pediatr Infect Dis J 26 (2007) 8-12
    • (2007) Pediatr Infect Dis J , vol.26 , pp. 8-12
    • Tramper-Stranders, G.A.1    Wolfs, T.F.2    Fleer, A.3    Kimpen, J.L.4    van der Ent, C.K.5
  • 75
    • 33645112270 scopus 로고    scopus 로고
    • Macrolide resistance of Staphylococcus aureus and Haemophilus species associated with long-term azithromycin use in cystic fibrosis
    • Phaff S.J., Tiddens H.A.W.M., Verbrugh H.A., and Ott A. Macrolide resistance of Staphylococcus aureus and Haemophilus species associated with long-term azithromycin use in cystic fibrosis. J Antimicrob Chemother 57 (2006) 741-746
    • (2006) J Antimicrob Chemother , vol.57 , pp. 741-746
    • Phaff, S.J.1    Tiddens, H.A.W.M.2    Verbrugh, H.A.3    Ott, A.4


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