-
1
-
-
0033001488
-
The NOD mouse model of type 1 diabetes: As good as it gets?
-
Atkinson MA, Leiter EH. The NOD mouse model of type 1 diabetes: as good as it gets? Nat Med 1999 5 : 601 4.
-
(1999)
Nat Med
, vol.5
, pp. 601-4
-
-
Atkinson, M.A.1
Leiter, E.H.2
-
2
-
-
23044436849
-
Vitamin D and type 1 diabetes mellitus: State of the art
-
Mathieu C, Badenhoop K. Vitamin D and type 1 diabetes mellitus: state of the art. Trends Endocrinol Metab 2005 16 : 261 6.
-
(2005)
Trends Endocrinol Metab
, vol.16
, pp. 261-6
-
-
Mathieu, C.1
Badenhoop, K.2
-
3
-
-
0031058466
-
Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative, but not positive selection of thymocytes in vivo
-
Brocker T, Riedinger M, Karjalainen K. Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative, but not positive selection of thymocytes in vivo. J Exp Med 1997 185 : 541 50.
-
(1997)
J Exp Med
, vol.185
, pp. 541-50
-
-
Brocker, T.1
Riedinger, M.2
Karjalainen, K.3
-
4
-
-
0030852624
-
Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells
-
Kurts C, Kosaka H, Carbone FR, Miller JF, Heath WR. Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cells. J Exp Med 1997 186 : 239 45.
-
(1997)
J Exp Med
, vol.186
, pp. 239-45
-
-
Kurts, C.1
Kosaka, H.2
Carbone, F.R.3
Miller, J.F.4
Heath, W.R.5
-
5
-
-
0035253699
-
Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo
-
Kurts C, Cannarile M, Klebba I, Brocker T. Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo. J Immunol 2001 166 : 1439 42.
-
(2001)
J Immunol
, vol.166
, pp. 1439-42
-
-
Kurts, C.1
Cannarile, M.2
Klebba, I.3
Brocker, T.4
-
6
-
-
0027217801
-
Autoimmune diabetes results from genetic defects manifest by antigen presenting cells
-
Serreze DV. Autoimmune diabetes results from genetic defects manifest by antigen presenting cells. FASEB 1993 7 : 1092 6.
-
(1993)
FASEB
, vol.7
, pp. 1092-6
-
-
Serreze, D.V.1
-
7
-
-
0033083396
-
Signs of immaturity of splenic dendritic cells from the autoimmune prone biobreeding rat: Consequences for the in vitro expansion of regulator and effector T cells
-
Delemarre FG, Simons PJ, de Heer HJ, Drexhage HA. Signs of immaturity of splenic dendritic cells from the autoimmune prone biobreeding rat: consequences for the in vitro expansion of regulator and effector T cells. J Immunol 1999 162 : 1795 801.
-
(1999)
J Immunol
, vol.162
, pp. 1795-801
-
-
Delemarre, F.G.1
Simons, P.J.2
De Heer, H.J.3
Drexhage, H.A.4
-
8
-
-
0028960483
-
Defective maturation and function of antigen-presenting cells in type 1 diabetes
-
Jansen A, van Hagen M, Drexhage HA. Defective maturation and function of antigen-presenting cells in type 1 diabetes. Lancet 1995 345 : 491 2.
-
(1995)
Lancet
, vol.345
, pp. 491-2
-
-
Jansen, A.1
Van Hagen, M.2
Drexhage, H.A.3
-
9
-
-
0027267769
-
Defective HLA class II expression in monocytes of type 1 diabetic patients
-
The Childhood Diabetes Finland Study Group.
-
Parkkonen P, Hyoty H, Huupponen T, Leinikki P, Tuomilehto-Wolf E, Knip M. Defective HLA class II expression in monocytes of type 1 diabetic patients. The Childhood Diabetes Finland Study Group. APMIS 1993 101 : 395 402.
-
(1993)
APMIS
, vol.101
, pp. 395-402
-
-
Parkkonen, P.1
Hyoty, H.2
Huupponen, T.3
Leinikki, P.4
Tuomilehto-Wolf, E.5
Knip, M.6
-
10
-
-
0034161714
-
1 alpha, 25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation
-
Penna G, Adorini M. 1 alpha, 25-dihydroxyvitamin D3 inhibits differentiation, maturation, activation, and survival of dendritic cells leading to impaired alloreactive T cell activation. J Immunol 2000 164 : 2405 11.
-
(2000)
J Immunol
, vol.164
, pp. 2405-11
-
-
Penna, G.1
Adorini, M.2
-
11
-
-
0035811015
-
Dendritic cell modulation by 1alpha, 25 dihydroxyvitamin D3 and its analogs: A vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo
-
Griffin MD, Lutz W, Phan VA, Bachman LA, McKean DJ, Kumar R. Dendritic cell modulation by 1alpha, 25 dihydroxyvitamin D3 and its analogs: a vitamin D receptor-dependent pathway that promotes a persistent state of immaturity in vitro and in vivo. Proc Natl Acad Sci USA 2001 98 : 6800 5.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 6800-5
-
-
Griffin, M.D.1
Lutz, W.2
Phan, V.A.3
Bachman, L.A.4
McKean, D.J.5
Kumar, R.6
-
12
-
-
0031974910
-
Inhibition of IL-12 production by 1, 25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene
-
D'Ambosio D, Cippitelli M, Cocciolo MG et al. Inhibition of IL-12 production by 1, 25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene. J Clin Invest 1998 101 : 252 62.
-
(1998)
J Clin Invest
, vol.101
, pp. 252-62
-
-
D'Ambosio, D.1
Cippitelli, M.2
Cocciolo, M.G.3
-
13
-
-
0036306094
-
Redirection of human autoreactive T cells upon interaction with dendritic cells modulated by TX527, an analog of 1, 25 dihydroxyvitamin D3
-
van Halteren AG, van Etten E, de Jong EC, Bouillon R, Roep BO, Mathieu C. Redirection of human autoreactive T cells upon interaction with dendritic cells modulated by TX527, an analog of 1, 25 dihydroxyvitamin D3. Diabetes 2002 51 : 2119 25.
-
(2002)
Diabetes
, vol.51
, pp. 2119-25
-
-
Van Halteren, A.G.1
Van Etten, E.2
De Jong, E.C.3
Bouillon, R.4
Roep, B.O.5
Mathieu, C.6
-
14
-
-
0036020679
-
1a,25-dihydroxyvitamin D3 analog enhances regulatory T cells and arrests autoimmune diabetes in NOD mice
-
Gregori S, Giarratana N, Smiroldo S, Uskokovic M, Adorini L. 1a,25-dihydroxyvitamin D3 analog enhances regulatory T cells and arrests autoimmune diabetes in NOD mice. Diabetes 2002 51 : 1367 74.
-
(2002)
Diabetes
, vol.51
, pp. 1367-74
-
-
Gregori, S.1
Giarratana, N.2
Smiroldo, S.3
Uskokovic, M.4
Adorini, L.5
-
15
-
-
27544499686
-
Immunoregulation by 1,25-dihydroxyvitamin D3: Basic concepts
-
van Etten E, Mathieu C. Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol 2005 97 : 93 101.
-
(2005)
J Steroid Biochem Mol Biol
, vol.97
, pp. 93-101
-
-
Van Etten, E.1
Mathieu, C.2
-
16
-
-
0029018309
-
Immuno-suppressive actions of 1,25-dihydroxyvitamin D3; Preferential inhibition of Th1 functions
-
Lemire JM, Archer DC, Beck L, Spiegelberg HL. Immuno-suppressive actions of 1,25-dihydroxyvitamin D3; preferential inhibition of Th1 functions. J Nutr 1995 125 : 1704S.
-
(1995)
J Nutr
, vol.125
-
-
Lemire, J.M.1
Archer, D.C.2
Beck, L.3
Spiegelberg, H.L.4
-
17
-
-
0033624113
-
1a,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543)
-
Overbergh L, Decallonne B, Waer M et al. 1a,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543). Diabetes 2000 49 : 1301 7.
-
(2000)
Diabetes
, vol.49
, pp. 1301-7
-
-
Overbergh, L.1
Decallonne, B.2
Waer, M.3
-
18
-
-
0031883711
-
Nuclear factor of activated T cells (NFAT) as a molecular target for 1 alpha, 25-dihydroxyvitamin D3-mediated effects
-
Takeuchi A, Reddy GS, Kobayashi T, Okano T, Park J, Sharma S. Nuclear factor of activated T cells (NFAT) as a molecular target for 1 alpha, 25-dihydroxyvitamin D3-mediated effects. J Immunol 1998 160 : 209 18.
-
(1998)
J Immunol
, vol.160
, pp. 209-18
-
-
Takeuchi, A.1
Reddy, G.S.2
Kobayashi, T.3
Okano, T.4
Park, J.5
Sharma, S.6
-
19
-
-
0035159578
-
Vitamin D analogs; Mechanism of action and therapeutic applications
-
Nagpal S, Jianfen 1 Boehm MF. Vitamin D analogs; mechanism of action and therapeutic applications. Curr Med Chem 2001 8 : 1661 79.
-
(2001)
Curr Med Chem
, vol.8
, pp. 1661-79
-
-
Nagpal, S.1
Jianfen, I.2
Boehm, M.F.3
-
20
-
-
0026649382
-
1,25-dihydroxyvitamin D3 prevents insulitis in NOD mice
-
Mathieu C, Laureys J, Sobis H, Vandeputte M, Waer M, Bouillon R. 1,25-dihydroxyvitamin D3 prevents insulitis in NOD mice. Diabetes 1992 41 : 1491 5.
-
(1992)
Diabetes
, vol.41
, pp. 1491-5
-
-
Mathieu, C.1
Laureys, J.2
Sobis, H.3
Vandeputte, M.4
Waer, M.5
Bouillon, R.6
-
22
-
-
0034061026
-
Impaired glucose tolerance in vitamin D deficiency can be corrected by calcium
-
Ismail A, Namala R. Impaired glucose tolerance in vitamin D deficiency can be corrected by calcium. J Nutr Biochem 2000 11 : 170 5.
-
(2000)
J Nutr Biochem
, vol.11
, pp. 170-5
-
-
Ismail, A.1
Namala, R.2
-
23
-
-
0027468996
-
Calcium is essential in normalizing intolerance to glucose that accompanies vitamin D depletion in vivo
-
Beaulieu C, Kestekian R, Havrankova J, Gascon-Barre M. Calcium is essential in normalizing intolerance to glucose that accompanies vitamin D depletion in vivo. Diabetes 1993 42 : 35 43.
-
(1993)
Diabetes
, vol.42
, pp. 35-43
-
-
Beaulieu, C.1
Kestekian, R.2
Havrankova, J.3
Gascon-Barre, M.4
-
24
-
-
0016589525
-
Synthesis of (6-3H)-1a-hydroxyvitamin D3 and its metabolism in vivo to (3H)-1a, 25-dihydroxyvitamin D
-
Holick MF, Holick SA, Tavela T, Gallagher B, Schnoes HK, DeLuca HF. Synthesis of (6-3H)-1a-hydroxyvitamin D3 and its metabolism in vivo to (3H)-1a, 25-dihydroxyvitamin D. Science 1975 190 : 576 8.
-
(1975)
Science
, vol.190
, pp. 576-8
-
-
Holick, M.F.1
Holick, S.A.2
Tavela, T.3
Gallagher, B.4
Schnoes, H.K.5
Deluca, H.F.6
-
25
-
-
0032112957
-
Activity of various hydroxylated viatmin D3 analogs for improving phosphorus utilization in chicks receiving diets adequate in vitamin D3
-
Biehl RR, Baker DH, DeLuca HF. Activity of various hydroxylated viatmin D3 analogs for improving phosphorus utilization in chicks receiving diets adequate in vitamin D3. Br Poult Sci 1998 39 : 408 12.
-
(1998)
Br Poult Sci
, vol.39
, pp. 408-12
-
-
Biehl, R.R.1
Baker, D.H.2
Deluca, H.F.3
-
26
-
-
0015657757
-
Biological activity of 1a-hydroxycholecalciferol, a synthetic analog of the hormonal form of vitamin D3
-
Haussler MR, Zerwekh JE, Hesse RH, Rizzardo E, Pechet MM. Biological activity of 1a-hydroxycholecalciferol, a synthetic analog of the hormonal form of vitamin D3. Proc Natl Acad Sci USA 1973 70 : 2248 52.
-
(1973)
Proc Natl Acad Sci USA
, vol.70
, pp. 2248-52
-
-
Haussler, M.R.1
Zerwekh, J.E.2
Hesse, R.H.3
Rizzardo, E.4
Pechet, M.M.5
-
27
-
-
0037423107
-
A wheat-based, diabetes-promoting diet induces a Th1-type cytokine bias in the gut of NOD mice
-
Flohe SB, Wasmuth HE, Kerad JB et al. A wheat-based, diabetes-promoting diet induces a Th1-type cytokine bias in the gut of NOD mice. Cytokine 2003 21 : 149 54.
-
(2003)
Cytokine
, vol.21
, pp. 149-54
-
-
Flohe, S.B.1
Wasmuth, H.E.2
Kerad, J.B.3
-
28
-
-
0036381993
-
A multi-centre, blinded international trial of the effect of A(1) and A(2) beta-casein variants on diabetes incidence in two rodent models of spontaneous type I diabetes
-
Beales PE, Elliott RB, Flohe S et al. A multi-centre, blinded international trial of the effect of A(1) and A(2) beta-casein variants on diabetes incidence in two rodent models of spontaneous type I diabetes. Diabetologia 2002 45 : 1240 6.
-
(2002)
Diabetologia
, vol.45
, pp. 1240-6
-
-
Beales, P.E.1
Elliott, R.B.2
Flohe, S.3
-
29
-
-
0026554156
-
The nonobese diabetic scid mouse: Model for spontaneous thymomagenesis associated with immunodeficiency
-
Prochazka M, Gaskins HR, Shultz LD, Leiter EH. The nonobese diabetic scid mouse: model for spontaneous thymomagenesis associated with immunodeficiency. Proc Natl Acad Sci USA 1992 89 : 3290 4.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 3290-4
-
-
Prochazka, M.1
Gaskins, H.R.2
Shultz, L.D.3
Leiter, E.H.4
-
30
-
-
0034176744
-
Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions
-
Graser RT, DiLorenzo TP, Wang F et al. Identification of a CD8 T cell that can independently mediate autoimmune diabetes development in the complete absence of CD4 T cell helper functions. J Immunol 2000 164 : 3913 18.
-
(2000)
J Immunol
, vol.164
, pp. 3913-18
-
-
Graser, R.T.1
Dilorenzo, T.P.2
Wang, F.3
-
31
-
-
0036917669
-
During the early prediabetic period in NOD mice, the pathogenic CD8+ T cell population comprises multiple antigenic specificities
-
DiLorenzo TP, Lieberman SM, Takaki T et al. During the early prediabetic period in NOD mice, the pathogenic CD8+ T cell population comprises multiple antigenic specificities. Clin Immunol 2002 105 : 332 41.
-
(2002)
Clin Immunol
, vol.105
, pp. 332-41
-
-
Dilorenzo, T.P.1
Lieberman, S.M.2
Takaki, T.3
-
33
-
-
33750818891
-
Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression
-
Serreze DV, Osborne MA, Chen YG et al. Partial versus full allogeneic hemopoietic chimerization is a preferential means to inhibit type 1 diabetes as the latter induces generalized immunosuppression. J Immunol 2006 177 : 6675 84.
-
(2006)
J Immunol
, vol.177
, pp. 6675-84
-
-
Serreze, D.V.1
Osborne, M.A.2
Chen, Y.G.3
-
34
-
-
0035459382
-
Autoreactive T cells in NOD mice can expand efficiently from a greatly reduced precursor pool
-
Serreze DV, Johnson EA, Chapman HD et al. Autoreactive T cells in NOD mice can expand efficiently from a greatly reduced precursor pool. Diabetes 2001 50 : 1992 2000.
-
(2001)
Diabetes
, vol.50
, pp. 1992-2000
-
-
Serreze, D.V.1
Johnson, E.A.2
Chapman, H.D.3
-
35
-
-
0026545730
-
Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice
-
Gerling IC, Serreze DV, Christianson SW, Leiter EH. Intrathymic islet cell transplantation reduces beta-cell autoimmunity and prevents diabetes in NOD/Lt mice. Diabetes 1992 41 : 1672 6.
-
(1992)
Diabetes
, vol.41
, pp. 1672-6
-
-
Gerling, I.C.1
Serreze, D.V.2
Christianson, S.W.3
Leiter, E.H.4
-
36
-
-
0037406493
-
Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice
-
Pierce MA, Chapman HD, Post CM et al. Adenovirus early region 3 antiapoptotic 10.4K, 14.5K, and 14.7K genes decrease the incidence of autoimmune diabetes in NOD mice. Diabetes 2003 52 : 1119 27.
-
(2003)
Diabetes
, vol.52
, pp. 1119-27
-
-
Pierce, M.A.1
Chapman, H.D.2
Post, C.M.3
-
37
-
-
0028357305
-
Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3
-
Mathieu C, Waer M, Laureys J, Rutgeerts O, Bouillon R. Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3. Diabetologia 1994 37 : 552 8.
-
(1994)
Diabetologia
, vol.37
, pp. 552-8
-
-
Mathieu, C.1
Waer, M.2
Laureys, J.3
Rutgeerts, O.4
Bouillon, R.5
-
38
-
-
3042554098
-
Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system
-
Mathieu C, van Etten E, Decallonne B et al. Vitamin D and 1,25-dihydroxyvitamin D3 as modulators in the immune system. J Steroid Biochem Mol Biol 2004 89-90 : 449 52.
-
(2004)
J Steroid Biochem Mol Biol
, vol.8990
, pp. 449-52
-
-
Mathieu, C.1
Van Etten, E.2
Decallonne, B.3
-
39
-
-
0006549587
-
1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells
-
Honma Y, Hozumi M, Abe E et al. 1 alpha,25-Dihydroxyvitamin D3 and 1 alpha-hydroxyvitamin D3 prolong survival time of mice inoculated with myeloid leukemia cells. Proc Natl Acad Sci USA 1983 80 : 201 4.
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 201-4
-
-
Honma, Y.1
Hozumi, M.2
Abe, E.3
-
40
-
-
0018849643
-
Comparative therapeutic effects of vitamin D3 and its derivatives on experimental renal osteodystrophy
-
Fukushima M, Niki R, Ohkawa H et al. Comparative therapeutic effects of vitamin D3 and its derivatives on experimental renal osteodystrophy. Endocrinology 1980 107 : 328 33.
-
(1980)
Endocrinology
, vol.107
, pp. 328-33
-
-
Fukushima, M.1
Niki, R.2
Ohkawa, H.3
-
42
-
-
0032702846
-
Dietary calcium is a major factor in 1,25-dihydroxycholecalciferol suppression of experimental autoimmune encephalomyelitis in mice
-
Cantorna MT, Humpal-Winter J, DeLuca HF. Dietary calcium is a major factor in 1,25-dihydroxycholecalciferol suppression of experimental autoimmune encephalomyelitis in mice. J Nutr 1999 129 : 1966 71.
-
(1999)
J Nutr
, vol.129
, pp. 1966-71
-
-
Cantorna, M.T.1
Humpal-Winter, J.2
Deluca, H.F.3
-
43
-
-
0043063940
-
Oral administration of 1,25-dihydroxyvitamin D3 completely protects NOD mice from insulin-dependent diabetes mellitus
-
Zella JB, McCary LC, DeLuca HF. Oral administration of 1,25-dihydroxyvitamin D3 completely protects NOD mice from insulin-dependent diabetes mellitus. Arch Biochem Biophys 2003 417 : 77 80.
-
(2003)
Arch Biochem Biophys
, vol.417
, pp. 77-80
-
-
Zella, J.B.1
McCary, L.C.2
Deluca, H.F.3
-
44
-
-
0034178251
-
Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells
-
Piemonti L, Monti P, Sironi M et al. Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells. J Immunol 2000 164 : 4443 51.
-
(2000)
J Immunol
, vol.164
, pp. 4443-51
-
-
Piemonti, L.1
Monti, P.2
Sironi, M.3
-
45
-
-
0034696812
-
Potent inhibition of dendritic cell differentiation and maturation by vitamin D analogs
-
Griffin MD, Lutz WH, Phan VA, Bachman LA, McKean DJ, Kumar R. Potent inhibition of dendritic cell differentiation and maturation by vitamin D analogs. Biochem Biophys Res Commun 2000 270 : 701 8.
-
(2000)
Biochem Biophys Res Commun
, vol.270
, pp. 701-8
-
-
Griffin, M.D.1
Lutz, W.H.2
Phan, V.A.3
Bachman, L.A.4
McKean, D.J.5
Kumar, R.6
-
46
-
-
0343238444
-
1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro
-
Berer A, Stockl J, Majdic O et al. 1,25-Dihydroxyvitamin D(3) inhibits dendritic cell differentiation and maturation in vitro. Exp Hematol 2000 28 : 575 83.
-
(2000)
Exp Hematol
, vol.28
, pp. 575-83
-
-
Berer, A.1
Stockl, J.2
Majdic, O.3
-
47
-
-
33845949937
-
1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells
-
Penna G, Amuchastegui S, Giarratana N et al. 1,25-Dihydroxyvitamin D3 selectively modulates tolerogenic properties in myeloid but not plasmacytoid dendritic cells. J Immunol 2007 178 : 145 53.
-
(2007)
J Immunol
, vol.178
, pp. 145-53
-
-
Penna, G.1
Amuchastegui, S.2
Giarratana, N.3
|