The first example of direct cyclopropylation of arylamines at the 2-position with magnesium cyclopropylidenes

Tetrahedron Letters

Volumn 49, Issue 1, 2008, Pages 169-174

  Yamada, Yukie ^a   Miura, Mariko ^a   Satoh, Tsuyoshi ^a  

^a TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

2 Cyclopropylated arylamine; Cyclopropylation; Magnesium carbenoid; Magnesium cyclopropylidene; Sulfoxide magnesium exchange reaction

Indexed keywords

AROMATIC AMINE; CYCLOPROPANE DERIVATIVE; ISOPROPYLMAGNESIUM CHLORIDE; MAGNESIUM CHLORIDE; SULFOXIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL PROCEDURES; SYNTHESIS; TEMPERATURE;

EID: 36549060486     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2007.10.122     Document Type: Article

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19. 4. After removal of the solvent, the product was purified by silica gel column chromatography to give 5c (24.5 mg, 60%).