Enhanced immune responses using plasmid DNA replicon vaccine encoding the Hc domain of Clostridium botulinum neurotoxin serotype A

Vaccine

Volumn 25, Issue 52, 2007, Pages 8843-8850

  Yu, Yun Zhou ^a   Zhang, Shu Ming ^b   Sun, Zhi Wei ^a   Wang, Shuang ^a   Yu, Wei Yuan ^a  

^a BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^b NATIONAL INSTITUTE FOR THE CONTROL OF PHARMACEUTICAL AND BIOLOGICAL PRODUCTS   (China)

Author keywords

Botulinum neurotoxin; DNA vaccine; Hc domain; Immunogenicity

Indexed keywords

AHC PROTEIN; ANTIBODY; BACTERIAL PROTEIN; BOTULINUM TOXIN A; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; PLASMID DNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BOTULISM; CONTROLLED STUDY; FEMALE; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOGENICITY; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REPLICON; SEMLIKI FOREST ALPHAVIRUS; SERODIAGNOSIS; TH2 CELL;

ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; BOTULINUM TOXIN TYPE A; BOTULISM; CELL PROLIFERATION; CLOSTRIDIUM BOTULINUM; FEMALE; IMMUNOGLOBULIN G; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; PLASMIDS; PROTEIN STRUCTURE, TERTIARY; SEMLIKI FOREST VIRUS; SURVIVAL ANALYSIS; T-LYMPHOCYTES; TH1 CELLS; TH2 CELLS; VACCINES, DNA;

EID: 36549052581     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2007.10.016     Document Type: Article

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