Interleukin (IL)-18 polymorphism 133C/G is associated with severe respiratory syncytial virus infection

Pediatric Infectious Disease Journal

Volumn 26, Issue 12, 2007, Pages 1094-1098

  Puthothu, Beena ^a   Krueger, Marcus ^a   Forster, Johannes ^a,b   Heinze, Jessica ^a   Weckmann, Markus ^a   Heinzmann, Andrea ^a,c  

^a UNIVERSITY OF FREIBURG   (Germany)

^b St Josef's Hospital   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

Author keywords

Association; Genetics; IL 18; Polymorphism; RSV

Indexed keywords

INTERLEUKIN 18;

ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EXON; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HUMAN; INTRON; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; STATISTICAL ANALYSIS; VIRUS INFECTION;

EID: 36549036304     PISSN: 08913668     EISSN: None     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181453579     Document Type: Article

References (43)

1. Darville T, Yamauchi T. Respiratory syncytial virus. Pediatr Rev. 1998;19:55-61.
2. Schauer U, Hoffjan S, Bittscheidt J, et al. RSV bronchiolitis and risk of wheeze and allergic sensitisation in the first year of life. Eur Respir J. 2002;20:1277-1283.
3. Sigurs N, Gustafsson PM, Bjarnason R, et al. Severe respiratory syncytial virus bronchiolitis in infancy and asthma and allergy at age 13. Am J Respir Crit Care Med. 2005;171:137-141.
4. Glezen WP, Taber LH, Frank AL, Kasel JA. Risk of primary infection and reinfection with respiratory syncytial virus. Am J Dis Child. 1986;140:543-546.
5. Berner R, Schwoerer F, Schumacher RF, Meder M, Forster J. Community and nosocomially acquired respiratory syncytial virus infection in a German paediatric hospital from 1988 to 1999. Eur J Pediatr. 2001;160:541-547.
6. Lemanske RF. Viral infections and asthma inception. Allergy Clin Immunol. 2004;114:1023-1026.
7. Roman M, Calhoun WJ, Hinton KL, et al. Respiratory syncytial virus infection in infants is associated with predominant Th-2-like response. Am J Respir Crit Care Med. 1997;156:190-195.
8. Dinarello CA. IL-18: A TH1-inducing, proinflammatory cytokine and nemember of the IL-1 family. J Allergy Clin Immunol. 1999;103(1 Pt 1):11-24.
9. Yoshimoto T, Okamura H, Tagawa YI, Iwakura Y, Nakanishi K. Interleukin 18 together with interleukin 12 inhibits IgE production by induction of interferon-gamma production from activated B cells. Proc Natl Acad Sci U S A. 1997;94:3948-3953.
10. Hoshino T, Wiltrout RH, Young HA. IL-18 is a potent coinducer of IL-13 in NK and T cells: a new potential role for IL-18 in modulating the immune response. J Immunol. 1999;162:5070-5077.
11. Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H. Interleukin-18 is a unique cytokine that stimulates both Th1 and Th2 responses depending on its cytokine milieu. Cytokine Growth Factor Rev. 2001;12:53-72.
12. Wild JS, Sigounas A, Sur N, et al. IFN-gamma-inducing factor (IL-18) increases allergic sensitization, serum IgE, Th2 cytokines, and airway eosinophilia in a mouse model of allergic asthma. J Immunol. 2000;164:2701-2710.
13. Higa S, Hirano T, Mayumi M, et al. Association between interleukin-18 gene polymorphism 105A/C and asthma. Clin Exp Allergy. 2003;33:1097-1102.
14. Kruse S, Kuehr J, Moseler M, et al. Polymorphisms in the IL 18 gene are associated with specific sensitization to common allergens and allergic rhinitis. J Allergy Clin Immunol. 2003;111:117-122.
15. Heinzmann A, Gerhold K, Ganter K, et al. Association study of polymorphisms within interleukin-18 in juvenile idiopathic arthritis and bronchial asthma. Allergy. 2004;59:845-849.
16. Liang XH, Cheung W, Heng CK, Wang DY. Reduced transcriptional activity in individuals with IL-18 gene variants detected from functional but not association study. Biochem Biophys Res Commun. 2005;338:736-741.
17. Szeszko JS, Howson JM, Cooper JD, et al. Analysis of polymorphisms of the interleukin-18 gene in type 1 diabetes and Hardy-Weinberg equilibrium testing. Diabetes. 2006;55:559-562.
18. Forster J, Ihorst G, Rieger CH, et al. Prospective population-based study of viral lower respiratory tract infections in children under 3 years of age (the PRI. DE study). Eur J Pediatr. 2004;163:709-716.
19. Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain-terminating inhibitors. Biotechnology. 1992;24:104-108.
20. Sasieni PD. From genotypes to genes: doubling the sample size. Biometrics. 1997;53(4):1253-1261.
21. Xu J, Turner A, Little J, Bleecker ER, Meyers DA. Positive results in association studies are associated with departure from Hardy-Weinberg equilibrium: hint for genotyping error? Hum Genet. 2002;111:573-574.
22. Zhao JH, Sham PC. Faster haplotype frequency estimation using unrelated subjects. Hum Hered. 2002;53:36-41.
23. Becker T, Knapp M. Maximum-likelihood estimation of haplotype frequencies in nuclear families. Genet Epidemiol. 2004;27:21-32.
24. Puthothu B, Krueger M, Forster J, Heinzmann A. Association between severe respiratory syncytial virus infection and IL13/IL4 haplotypes. J Infect Dis. 2006;193:438-441.
25. Hoebee B, Rietveld E, Bont L, et al. Association of severe respiratory syncytial virus bronchiolitis with interleukin-4 and interleukin-4 receptor alpha polymorphisms. J Infect Dis. 2003;187:2-11.
26. Choi EH, Lee HJ, Yoo T, Chanock SJ. A common haplotype of interleukin-4 gene IL4 is associated with severe respiratory syncytial virus disease in Korean children. J Infect Dis. 2002;186:1207-1211.
27. Lahti M, Lofgren J, Marttila R, et al. Surfactant protein D gene polymorphism associated with severe respiratory syncytial virus infection. Pediatr Res. 2002;51:696-699.
28. Hoebee B, Bont L, Rietveld E, et al. Influence of promoter variants of interleukin-10, interleukin-9, and tumor necrosis factor-alpha genes on respiratory syncytial virus bronchiolitis. J Infect Dis. 2004;189:239-247.
29. Hull J, Thomson A, Kwiatkowski D. Association of respiratory syncytial virus bronchiolitis with the interleukin 8 gene region in UK families. Thorax. 2000;55:1023-1027.
30. Tal G, Mandelberg A, Dalal I, et al. Association between common Toll-like receptor 4 mutations and severe respiratory syncytial virus disease. J Infect Dis. 2004;189:2057-2063.
31. Puthothu B, Forster J, Heinzmann A, Krueger M. TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease. Dis Markers. 2006;22:303-308.
32. Lofgren J, Ramet M, Renko M, et al. Association between surfactant protein A gene locus and severe respiratory syncytial virus infection in infants. J Infect Dis. 2002;185:283-289.
33. Puthothu B, Forster J, Heinze J, Heinzmann A, Krueger M. Surfactant protein B polymorphisms are associated with severe respiratory syncytial virus infection, but not with asthma. BMC Pulm Med. 2007;7:6.
34. Puthothu B, Krueger M, Heinze J, Forster J, Heinzmann A. Haplotypes of surfactant protein C are associated with common paediatric lung diseases. Pediatr Allergy Immunol. 2006;17:572-577.
35. Sivalingam SP, Yoon KH, Koh DR, Fong KY. Single-nucleotide polymorphisms of the interleukin-18 gene promoter region in rheumatoid arthritis patients: protective effect of AA genotype. Tissue Antigens. 2003;62:498-504.
36. Novak N, Kruse S, Potreck J, Maintz L, Jenneck C, Weidinger S, Fimmers R, Bieber T. Single nucleotide polymorphisms of the IL18 gene are associated with atopic eczema. J Allergy Clin Immunol. 2005;115:828-833.
37. Kretowski A, Mironczuk K, Karpinska A, et al. Interleukin-18 promoter polymorphisms in type 1 diabetes. Diabetes. 2002;51:3347-3349.
38. Pratesi C, Bortolin MT, Bidoli E, et al. Interleukin-10 and interleukin-18 promoter polymorphisms in an Italian cohort of patients with undifferentiated carcinoma of nasopharyngeal type. Cancer Immunol Immunother. 2006;55:23-30.
39. Kim YM, Kang HS, Paik SG, et al. Roles of IFN consensus sequence binding protein and PU. 1 in regulating IL-18 gene expression. J Immunol. 1999;163:2000-2007.
40. Tone M, Thompson SA, Tone Y, Fairchild PJ, Waldmann H. Regulation of IL-18 (IFN-gamma-inducing factor) gene expression. J Immunol. 1997;159:6156-6163.
41. Giedraitis V, He B, Huang WX, Hillert J. Cloning and mutation analysis of the human IL-18 promoter: a possible role of polymorphisms in expression regulation. J Neuroimmunol. 2001;112:146-152.
42. Arimitsu J, Hirano T, Higa S, et al. IL-18 gene polymorphisms affect IL-18 production capability by monocytes. Biochem Biophys Res Commun. 2006;342:1413-1416.
43. van Benten IJ, van Drunen CM, Koopman LP, et al. RSV-induced bronchiolitis but not upper respiratory tract infection is accompanied by an increased nasal IL-18 response. J Med Virol. 2003;71:290-297.