Function analysis of sequences in human APOBEC3G involved in Vif-mediated degradation

Virology

Volumn 370, Issue 1, 2008, Pages 113-121

  Zhang, Li ^a,c   Saadatmand, Jenan ^a,b   Li, Xiaoyu ^a,b   Guo, Fei ^a   Niu, Meijuan ^a   Jiang, Jiandong ^c   Kleiman, Lawrence ^a,b   Cen, Shan ^a,b,c  

^a MCGILL UNIVERSITY   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

APOBEC3G; HIV 1; Polyubiquitination; Proteasome dependent degradation; Vif

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; VIF PROTEIN;

ARTICLE; CELL LYSATE; CONTROLLED STUDY; DELETION MUTANT; FUNCTIONAL ASSESSMENT; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNOPRECIPITATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; VIRUS REPLICATION;

AMINO ACID MOTIFS; CELL LINE; CYTIDINE DEAMINASE; GENE DELETION; HIV-1; HUMANS; IMMUNOPRECIPITATION; POLYUBIQUITIN; PROTEASOME ENDOPEPTIDASE COMPLEX; VIF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 36549004535     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2007.08.027     Document Type: Article

References (35)

1. Bogerd H.P., Doehle B.P., Wiegand H.L., and Cullen B.R. A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor. Proc. Natl. Acad. Sci. U. S. A. 101 11 (2004) 3770-3774
2. Cen S., Guo F., Niu M., Saadatmand J., Deflassieux J., and Kleiman L. The interaction between HIV-1 Gag and APOBEC3G. J. Biol. Chem. 279 32 (2004) 33177-33184
3. Conticello S.G., Harris R.S., and Neuberger M.S. The Vif protein of HIV triggers degradation of the human antiretroviral DNA deaminase APOBEC3G. Curr. Biol. 13 22 (2003) 2009-2013
4. Dettenhofer M., Cen S., Carlson B.A., Kleiman L., and Yu X.F. Association of HIV-1 Vif with RNA and its role in reverse transcription. J. Virol. 74 (2000) 8938-8945
5. Fisher A.G., Ensoli B., Ivanoff L., Chamberlain M., Petteway S., Ratner L., Gallo R.C., and Wong-Staal F. The sor gene of HIV-1 is required for efficient virus transmission in vitro. Science 237 4817 (1987) 888-893
6. Gabuzda D.H., Lawrence K., Langhoff E., Terwilliger E., Dorfman T., Haseltine W.A., and Sodroski J. Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes. J. Virol. 66 11 (1992) 6489-6495
7. Gibbs J.S., Regier D.A., and Desrosiers R.C. Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes. AIDS Res. Hum. Retrovir. 10 5 (1994) 607-616
8. Lys annealing to viral RNA, and viral infectivity in HIV-1. J. Virol. 77 (2003) 9817-9822
9. Lys3-primed reverse transcription by human APOBEC3G during HIV-1 replication. J. Virol. 80 (2006) 11710-11722
10. Huthoff H., and Malim M.H. Identification of amino acid residues in APOBEC3G required for regulation by human immunodeficiency virus type 1 Vif and Virion encapsidation. J. Virol. 81 8 (2007) 3807-3815
11. Jarmuz A., Chester A., Bayliss J., Gisbourne J., Dunham I., Scott J., and Navaratnam N. An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Genomics 79 3 (2002) 285-296
12. Kan N.C., Franchini G., Wong-Staal F., DuBois G.C., Robey W.G., Lautenberger J.A., and Papas T.S. Identification of HTLV-III/LAV sor gene product and detection of antibodies in human sera. Science 231 4745 (1986) 1553-1555
13. Kao S., Khan M.A., Miyagi E., Plishka R., Buckler-White A., and Strebel K. The human immunodeficiency virus type 1 Vif protein reduces intracellular expression and inhibits packaging of APOBEC3G (CEM15), a cellular inhibitor of virus infectivity. J. Virol. 77 21 (2003) 11398-11407
14. Kao S., Miyagi E., Khan M.A., Takeuchi H., Opi S., Goila-Gaur R., and Strebel K. Production of infectious human immunodeficiency virus type 1 does not require depletion of APOBEC3G from virus-producing cells. Retrovirology 1 (2004) 27
15. Khorchid A., Halwani R., Wainberg M.A., and Kleiman L. Role of RNA in facilitating Gag/Gag-Pol interaction. J. Virol. 76 (2002) 4131-4137
16. Kile B.T., Schulman B.A., Alexander W.S., Nicola N.A., Martin H.M., and Hilton D.J. The SOCS box: a tale of destruction and degradation. Trends Biochem. Sci. 27 5 (2002) 235-241
17. Lee T.H., Coligan J.E., Allan J.S., McLane M.F., Groopman J.E., and Essex M. A new HTLV-III/LAV protein encoded by a gene found in cytopathic retroviruses. Science 231 4745 (1986) 1546-1549
18. Li J., Potash M.J., and Volsky D.J. Functional domains of APOBEC3G required for antiviral activity. J. Cell. Biochem. 92 3 (2004) 560-572
19. Liu B., Yu X., Luo K., Yu Y., and Yu X.F. Influence of primate lentiviral Vif and proteasome inhibitors on human immunodeficiency virus type 1 virion packaging of APOBEC3G. J. Virol. 78 4 (2004) 2072-2081
20. Luo K., Xiao Z., Ehrlich E., Yu Y., Liu B., Zheng S., and Yu X.F. Primate lentiviral virion infectivity factors are substrate receptors that assemble with cullin 5-E3 ligase through a HCCH motif to suppress APOBEC3G. Proc. Natl. Acad. Sci. U. S. A. 102 32 (2005) 11444-11449
21. Madani N., and Kabat D. An endogenous inhibitor of human immunodeficiency virus in human lymphocytes is overcome by the viral Vif protein. J. Virol. 72 12 (1998) 10251-10255
22. Mangeat B., Turelli P., Liao S., and Trono D. A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action. J. Biol. Chem. 279 15 (2004) 14481-14483
23. Mariani R., Chen D., Schrofelbauer B., Navarro F., Konig R., Bollman B., Munk C., Nymark-McMahon H., and Landau N.R. Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Cell 114 1 (2003) 21-31
24. Marin M., Rose K.M., Kozak S.L., and Kabat D. HIV-1 Vif protein binds the editing enzyme APOBEC3G and induces its degradation. Nat. Med. 9 11 (2003) 1398-1403
25. Opi S., Kao S., Goila-Gaur R., Khan M.A., Miyagi E., Takeuchi H., and Strebel K. Human immunodeficiency virus type 1 Vif inhibits packaging and antiviral activity of a degradation-resistant APOBEC3G variant. J. Virol. (2007)
26. Pickart C.M. Ubiquitin enters the new millennium. Mol. Cell 8 3 (2001) 499-504
27. Schrofelbauer B., Chen D., and Landau N.R. A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif). Proc. Natl. Acad. Sci. U. S. A. 101 11 (2004) 3927-3932
28. Sheehy A.M., Gaddis N.C., Choi J.D., and Malim M.H. Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. Nature 418 6898 (2002) 646-650
29. Simon J.H., and Malim M.H. The human immunodeficiency virus type 1 Vif protein modulates the postpenetration stability of viral nucleoprotein complexes. J. Virol. 70 8 (1996) 5297-5305
30. Simon J.H., Gaddis N.C., Fouchier R.A., and Malim M.H. Evidence for a newly discovered cellular anti-HIV-1 phenotype. Nat. Med. 4 12 (1998) 1397-1400
31. Sodroski J., Goh W.C., Rosen C., Tartar A., Portetelle D., Burny A., and Haseltine W. Replicative and cytopathic potential of HTLV-III/LAV with sor gene deletions. Science 231 4745 (1986) 1549-1553
32. Stopak K., de Noronha C., Yonemoto W., and Greene W.C. HIV-1 Vif blocks the antiviral activity of APOBEC3G by impairing both its translation and intracellular stability. Mol. Cell 12 3 (2003) 591-601
33. Strebel K., Daugherty D., Clouse K., Cohen D., Folks T., and Martin M.A. The HIV 'A' (sor) gene product is essential for virus infectivity. Nature 328 6132 (1987) 728-730
34. von Schwedler U., Song J., Aiken C., and Trono D. Vif is crucial for human immunodeficiency virus type 1 proviral DNA synthesis in infected cells. J. Virol. 67 8 (1993) 4945-4955
35. Yu X., Yu Y., Liu B., Luo K., Kong W., Mao P., and Yu X.F. Induction of APOBEC3G ubiquitination and degradation by an HIV-1 Vif-Cul5-SCF complex. Science 302 5647 (2003) 1056-1060