Calcium phosphate ceramics for bone tissue engineering

Tissue Engineering

Volumn , Issue , 2007, Pages 131-148

  Ruhé, P Quinten ^a   Wolke, Joop G C ^a   Spauwen, Paul H M ^a   Jansen, John A ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 36448957795     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (96)

1. LeGeros, R.Z., Properties of osteoconductive biomaterials: calcium phosphates. Clin. Orthop. 81-98, 2002.
2. Dorozhkin, S.V. and Epple, M., Biological and medical significance of calcium phosphates. Angew. Chem. Int. Ed. Engl., 41: 3130-3146, 2002.
3. Eanes, E.D., Amorphous calcium phosphate. Monogr. Oral Sci., 18: 130-147, 2001.
4. LeGeros, R.Z., Calcium phosphates in oral biology and medicine.Monogr. Oral Sci., 15: 1-201, 1991.
5. Vaccaro, A.R., The role of the osteoconductive scaffold in synthetic bone graft. Orthopedics 25:s571-s578, 2002.
6. Ravaglioli, A. and Krajewski, A., Bioceramics. London: Chapman & Hall, 1992.
7. Le Huec, J.C., Schaeverbeke, T., Clement, D., Faber, J., and Le Rebeller, A., Influence of porosity on the mechanical resistance of hydroxyapatite ceramics under compressive stress. Biomaterials 16:113-118, 1995.
8. Yuan, H., Kurashina, K., de Bruijn, J.D., Li, Y., de Groot, K., and Zhang, X., A preliminary study on osteoinduction of two kinds of calcium phosphate ceramics. Biomaterials, 20: 1799-1806, 1999.
9. Tsuruga, E., Takita, H., Itoh, H., Wakisaka, Y., and Kuboki, Y., Pore size of porous hydroxyapatite as the cell-substratum controls BMP-induced osteogenesis. J. Biochem. (Tokyo), 121: 317-324, 1997.
10. Kuboki, Y., Jin, Q., and Takita, H., Geometry of carriers controlling phenotypic expression in BMP-induced osteogenesis and chondrogenesis. J. Bone Joint Surg. Am. 83-A (Suppl 1): 105-115, 2001.
11. Ripamonti, U., Crooks, J., and Kirkbride, A.N., Sintered porous hydroxyapatites with intrinsic osteoinductive activity: geometric induction of bone formation. S. Afr. J. Sci., 95: 335-343, 1999.
12. Ripamonti, U., Smart biomaterials with intrinsic osteoinductivity: Geometric control of bone differentiation. In Bone Engineering, ed. Davies, J.E., Toronto: EM Squared Incorporated, 2000, pp. 215-222.
13. Jansen, J.A., Wolke, J.G., Swann, S., van der Waerden, J.P., and de Groot, K., Application of magnetron sputtering for producing ceramic coatings on implant materials. Clin. Oral. Implants Res.4: 28-34, 1993.
14. Roy, D.M. and Linnehan, S.K., Hydroxyapatite formed from coral skeletal carbonate by hydrothermal exchange. Nature, 247: 220-222, 1974.
15. Truumees, E. and Herkowitz, H.N., Alternatives to autologous bone harvest in spine surgery. Univ. Penn. Orthop. J., 12: 77-88, 1999.
16. Brown, W.E. and Chow, L.C., Dental restorative cement pastes. U.S. Patent (4, 518, 430), 1985.
17. Chow, L.C., Calcium phosphate cements. Monogr. Oral Sci., 18: 148-163, 2001.
18. Schmitz, J.P., Hollinger, J.O., and Milam, S.B., Reconstruction of bone using calcium phosphate bone cements: a critical review. J. Oral Maxillofac. Surg., 57: 1122-1126, 1999.
19. Ooms, E.M., Wolke, J.G., van de Heuvel, M.T., Jeschke, B., and Jansen, J.A., Histological evaluation of the bone response to calcium phosphate cement implanted in cortical bone. Biomaterials 24:989-1000, 2003.
20. Comuzzi, L., Ooms, E., and Jansen, J.A., Injectable calcium phosphate cement as a filler for bone defects around oral implants: an experimental study in goats. Clin. Oral Implants Res., 13: 304-311, 2002.
21. Ooms, E.M., Wolke, J.G., van der Waerden, J.P., and Jansen, J.A., Trabecular bone response to injectable calcium phosphate (Ca-P) cement. J. Biomed. Mater. Res., 61: 9-18, 2002.
22. Driessens, F.C., Boltong, M.G., Bermudez, O., and Planell, J.A., Formulation and setting times of some calcium orthophosphate cements: a pilot study. J. Mater. Sci. Mater. Med., 4: 503-508, 1993.
23. Ishikawa, K., Takagi, S., Chow, L.C., Ishikawa, Y., Eanes, E.D., and Asaoka, K., Behavior of a calcium phosphate cement in simulated blood plasma in vitro. Dent. Mater., 10: 26-32, 1994.
24. Takagi, S., Chow, L.C., Markovic, M., Friedman, C.D., and Costantino, P.D., Morphological and phase characterizations of retrieved calcium phosphate cement implants. J. Biomed. Mater. Res. 58:36-41, 2001.
25. Ducheyne, P. and Qiu, Q., Bioactive ceramics: the effect of surface reactivity on bone formation and bone cell function. Biomaterials, 20: 2287-2303, 1999.
26. Davies, J.E., Mechanisms of endosseous integration. Int. J. Prosthodont., 11: 391-401, 1998.
27. Rosengren, A., Pavlovic, E., Oscarsson, S., Krajewski, A., Ravaglioli, A., and Piancastelli, A., Plasma protein adsorption pattern on characterized ceramic biomaterials. Biomaterials, 23: 1237-1247, 2002.
28. Rosengren, A., Oscarsson, S., Mazzocchi, M., Krajewski, A., and Ravaglioli, A., Protein adsorption onto two bioactive glass-ceramics. Biomaterials, 24: 147-155, 2003.
29. Radin, S., Ducheyne, P., Berthold, P., and Decker, S., Effect of serum proteins and osteoblasts on the surface transformation of a calcium phosphate coating: a physicochemical and ultrastructural study. J. Biomed. Mater. Res., 39: 234-243, 1998.
30. Ong, J.L., Chittur, K.K., and Lucas, L.C., Dissolution/reprecipitation and protein adsorption studies of calcium phosphate coatings by FT-IR/ATR techniques. J. Biomed. Mater. Res., 28: 1337-1346, 1994.
31. Combes, C. and Rey, C., Adsorption of proteins and calcium phosphate materials bioactivity. Biomaterials, 23: 2817-2823, 2002.
32. Maniatopoulos, C., Sodek, J., and Melcher, A.H., Bone formation in vitro by stromal cells obtained from bone marrow of young adult rats. Cell Tissue Res., 254: 317-330, 1988.
33. Hanada, K., Dennis, J.E., and Caplan, A.I., Stimulatory effects of basic fibroblast growth factor and bone morphogenetic protein-2 on osteogenic differentiation of rat bone marrow-derived mesenchymal stem cells. J. Bone Miner. Res., 12: 1606-1614, 1997.
34. Okumura, M., Ohgushi, H., Dohi, Y., Katuda, T., Tamai, S., Koerten, H.K., and Tabata, S., Osteoblastic phenotype expression on the surface of hydroxyapatite ceramics. J. Biomed. Mater. Res. 37:122-129, 1997.
35. Boo, J.S., Yamada, Y., Okazaki, Y., Hibino, Y., Okada, K., Hata, K., Yoshikawa, T., Sugiura, Y., and Ueda, M., Tissue-engineered bone using mesenchymal stem cells and a biodegradable scaffold. J. Craniofac. Surg., 13: 231-239, 2002.
36. Dong, J., Uemura, T., Shirasaki, Y., and Tateishi, T., Promotion of bone formation using highly pure porous beta-TCP combined with bone marrow-derived osteoprogenitor cells. Biomaterials, 23: 4493-4502, 2002.
37. Uemura, T., Dong, J., Wang, Y., Kojima, H., Saito, T., Iejima, D., Kikuchi, M., Tanaka, J., and Tateishi, T., Transplantation of cultured bone cells using combinations of scaffolds and culture techniques. Biomaterials, 24: 2277-2286, 2003.
38. Hartman, E.H., Ruhe, P.Q., Spauwen, P.H., and Jansen, J.A., Ectopic bone formation in rats:comparison of biphasic ceramic implants seeded with cultured rat bone marrow cells in a pedicled and a revascularised muscle flap. Unpublished work, 2004.
39. Kruyt, M.C., de Bruijn, J.D., Wilson, C.E., Oner, F.C., van Blitterswijk, C.A., Verbout, A.J., and Dhert, W.J., Viable osteogenic cells are obligatory for tissue-engineered ectopic bone formation in goats. Tissue Eng., 9: 327-336, 2003.
40. Kadiyala, S., Young, R.G., Thiede, M.A., and Bruder, S.P., Culture expanded canine mesenchymal stem cells possess osteochondrogenic potential in vivo and in vitro. Cell Transplant, 6: 125-134, 1997.
41. Kruyt, M.C., Dhert, W.J., Yuan, H., Wilson, C.E., van Blitterswijk, C.A., Verbout, A.J., and de Bruijn, J.D., Bone tissue engineering in a critical size defect compared to ectopic implantations in the goat. J. Orthop. Res., 22: 544-551, 2004.
42. Schliephake, H., Knebel, J.W., Aufderheide, M., and Tauscher, M., Use of cultivated osteoprogenitor cells to increase bone formation in segmental mandibular defects: an experimental pilot study in sheep. Int. J. Oral Maxillofac. Surg., 30: 531-537, 2001.
43. Bruder, S.P., Kraus, K.H., Goldberg, V.M., and Kadiyala, S., The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine segmental bone defects. J. Bone Joint Surg. Am., 80: 985-996, 1998.
44. Kon, E., Muraglia, A., Corsi, A., Bianco, P., Marcacci, M., Martin, I., Boyde, A., Ruspantini, I., Chistolini, P., Rocca, M., Giardino, R., Cancedda, R., and Quarto, R., Autologous bone marrow stromal cells loaded onto porous hydroxyapatite ceramic accelerate bone repair in critical-size defects of sheep long bones. J. Biomed. Mater. Res., 49: 328-337, 2000.
45. Petite, H., Viateau, V., Bensaid, W., Meunier, A., De Pollak, C, Bourguignon, M., Oudina, K., Sedel, L., and Guillemin, G., Tissue-engineered bone regeneration. Nat. Biotechnol., 18: 959-963, 2000.
46. Shang, Q., Wang, Z., Liu, W., Shi, Y., Cui, L., and Cao, Y., Tissue-engineered bone repair of sheep cranial defects with autologous bone marrow stromal cells. J. Craniofac. Surg., 12: 586-593, 2001.
47. Nakashima, M. and Reddi, A.H., The application of bone morphogenetic proteins to dental tissue engineering. Nat. Biotechnol., 21: 1025-1032, 2003.
48. Reddi, A.H. and Cunningham, N.S., Initiation and promotion of bone differentiation by bone morphogenetic proteins. J. Bone Miner. Res., 8: 499-502, 1993.
49. Uludag, H., Gao, T., Porter, T.J., Friess, W., and Wozney, J.M., Delivery systems for BMPs: factors contributing to protein retention at an application site. J. Bone Joint Surg. Am. 83-A: 128-135, 2001.
50. Cunningham, N.S., Paralkar, V., and Reddi, A.H., Osteogenin and recombinant bone morphogenetic protein 2B are chemotactic for human monocytes and stimulate transforming growth factor beta 1 mRNA expression. Proc. Natl Acad. Sci. USA, 89: 11740-11744, 1992.
51. Li, R.H. and Wozney, J.M., Delivering on the promise of bone morphogenetic proteins. Trends Biotechnol., 19: 255-265, 2001.
52. Louis-Ugbo, J., Kim, H.S., Boden, S.D., Mayr, M.T., Li, R.C., Seeherman, H., D’Augusta, D., Blake, C., Jiao, A., and Peckham, S., Retention of 125I-labeled recombinant human bone morphogenetic protein-2 by biphasic calcium phosphate or a composite sponge in a rabbit posterolateral spine arthrodesis model. J. Orthop. Res., 20: 1050-1059, 2002.
53. Uludag, H., D’Augusta, D., Golden, J., Li, J., Timony, G., Riedel, R., and Wozney, J.M., Implantation of recombinant human bone morphogenetic proteins with biomaterial carriers: a correlation between protein pharmacokinetics and osteoinduction in the rat ectopic model. J. Biomed. Mater. Res., 50: 227-238, 2000.
54. Uludag, H., D’Augusta, D., Palmer, R., Timony, G., and Wozney, J., Characterization of rhBMP-2 pharmacokinetics implanted with biomaterial carriers in the rat ectopic model. J. Biomed. Mater. Res., 46: 193-202, 1999.
55. Li, R.H., Bouxsein, M.L., Blake, C.A., D’Augusta, D., Kim, H., Li, X.J., Wozney, J.M., and Seeherman, H.J., rhBMP-2 injected in a calcium phosphate paste (alpha-BSM) accelerates healing in the rabbit ulnar osteotomy model. J. Orthop. Res., 21: 997-1004, 2003.
56. Herr, G., Hartwig, C.H., Boll, C., and Kusswetter, W., Ectopic bone formation by composites of BMP and metal implants in rats. Acta Orthop. Scand., 67: 606-610, 1996.
57. Kirsch, T., Sebald, W., and Dreyer, M.K., Crystal structure of theBMP-2-BRIA ectodomain complex. Nat. Struct. Biol., 7: 492-496, 2000.
58. Nickel, J., Dreyer, M.K., Kirsch, T., and Sebald, W., The crystal structure of the BMP-2: BMPR-IA complex and the generation of BMP-2 antagonists. J. Bone Joint Surg. Am. 83-A: 7-14, 2001.
59. Santos, E.M., Radin, S., Shenker, B.J., Shapiro, I.M., and Ducheyne, P., Si-Ca-P xerogels and bone morphogenetic protein act synergistically on rat stromal marrow cell differentiation in vitro. J. Biomed. Mater. Res., 41: 87-94, 1998.
60. Blom, E.J., Klein-Nulend, J., Yin, L., vanWaas, M.A., and Burger, E.H., Transforming growth factorbeta1 incorporated in calcium phosphate cement stimulates osteotransductivity in rat calvarial bone defects. Clin. Oral Implants Res., 12: 609-616, 2001.
61. Lee, D.D., Tofighi, A., Aiolova, M., Chakravarthy, P., Catalano, A., Majahad, A., and Knaack, D., Alpha-BSM: a biomimetic bone substitute and drug delivery vehicle. Clin. Orthop. 396-405, 1999.
62. Li, R.H., D’Augusta, D., Blake, C., Bouxsein, M., Wozney, J.M., Li, J., Stevens, M., Kim, H., and Seeherman, H., rhBMP-2 delivery and efficacy in an injectable calcium phosphate based matrix. The 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, 2001.
63. Isobe, M., Yamazaki, Y., Oida, S., Ishihara, K., Nakabayashi, N., and Amagasa, T., Bone morphogenetic protein encapsulated with a biodegradable and biocompatible polymer. J. Biomed. Mater. Res., 32: 433-438, 1996.
64. Lu, L., Yaszemski, M.J., and Mikos, A.G., TGF-beta1 release from biodegradable polymer microparticles:its effects on marrow stromal osteoblast function. J. Bone Joint Surg. Am. 83-A (Suppl 1):82-91, 2001.
65. Miyamoto, S., Takaoka, K., Okada, T., Yoshikawa, H., Hashimoto, J., Suzuki, S., and Ono, K., Polylactic acid-polyethylene glycol block copolymer. A new biodegradable synthetic carrier for bone morphogenetic protein. Clin. Orthop. 333-343, 1993.
66. Oldham, J.B., Lu, L., Zhu, X., Porter, B.D., Hefferan, T.E., Larson, D.R., Currier, B.L., Mikos, A.G., and Yaszemski, M.J., Biological activity of rhBMP-2 released from PLGA microspheres. J. Biomech. Eng., 122: 289-292, 2000.
67. Pean, J.M., Venier-Julienne, M.C., Boury, F., Menei, P., Denizot, B., and Benoit, J.P., NGF release from poly(d, l-lactide-co-glycolide) microspheres. Effect of some formulation parameters on encapsulated NGF stability. J. Control. Release., 56: 175-187, 1998.
68. Peter, S.J., Lu, L., Kim, D.J., Stamatas, G.N., Miller, M.J., Yaszemski, M.J., and Mikos, A.G., Effects of transforming growth factor beta1 released from biodegradable polymer microparticles on marrow stromal osteoblasts cultured on poly(propylene fumarate) substrates. J. Biomed. Mater. Res. 50:452-462, 2000.
69. Murata, M., Inoue, M., Arisue, M., Kuboki, Y., and Nagai, N., Carrier-dependency of cellular differentiation induced by bone morphogenetic protein in ectopic sites. Int. J. Oral Maxillofac. Surg., 27: 391-396, 1998.
70. Ripamonti, U., Ma, S., and Reddi, A.H., The critical role of geometry of porous hydroxyapatite delivery system in induction of bone by osteogenin, a bone morphogenetic protein. Matrix 12:202-212, 1992.
71. Sumner, D.R., Turner, T.M., Urban, R.M., Turek, T., Seeherman, H., and Wozney, J.M., Locally delivered rhBMP-2 enhances bone ingrowth and gap healing in a canine model. J. Orthop. Res. 22:58-65, 2004.
72. Kuboki, Y., Saito, T., Murata, M., Takita, H., Mizuno, M., Inoue, M., Nagai, N., and Poole, A.R., Two distinctive BMP-carriers induce zonal chondrogenesis and membranous ossification, respectively; geometrical factors of matrices for cell-differentiation. Connect. Tissue. Res., 32: 219-226, 1995.
73. Kroese-Deutman, H.C., Ruhe, P.Q., Spauwen P.H., and Jansen J.A., Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants inserted at an ectopic site in rabbits. Biomaterials, 26: 1131-1138, 2005.
74. Kuboki, Y., Takita, H., Kobayashi, D., Tsuruga, E., Inoue, M., Murata, M., Nagai, N., Dohi, Y., and Ohgushi, H., BMP-induced osteogenesis on the surface of hydroxyapatite with geometrically feasible and nonfeasible structures: topology of osteogenesis. J. Biomed. Mater. Res., 39: 190-199, 1998.
75. Ohura, K., Hamanishi, C., Tanaka, S., and Matsuda, N., Healing of segmental bone defects in rats induced by a beta-TCP-MCPM cement combined with rhBMP-2. J. Biomed. Mater. Res. 44:168-175, 1999.
76. Glass, D.A., Mellonig, J.T., and Towle, H.J., Histologic evaluation of bone inductive proteins complexed with coralline hydroxylapatite in an extraskeletal site of the rat. J. Periodontol., 60: 121-126, 1989.
77. Herr, G., Wahl, D., and Kusswetter, W., Osteogenic activity of bone morphogenetic protein and hydroxyapatite composite implants. Ann. Chir. Gynaecol. Suppl., 207: 99-107, 1993.
78. Clarke, S.A., Brooks, R.A., Lee, P.T., and Rushton, N., Bone growth into a ceramic-filled defect around an implant. The response to transforming growth factor beta1. J. Bone Joint Surg. Br. 86:126-134, 2004.
79. Ono, I., Ohura, T., Murata, M., Yamaguchi, H., Ohnuma, Y., and Kuboki, Y., A study on bone induction in hydroxyapatite combined with bone morphogenetic protein. Plast. Reconstr. Surg. 90:870-879, 1992.
80. Ono, I., Inoue, M., and Kuboki, Y., Promotion of the osteogenetic activity of recombinant human bone morphogenetic protein by prostaglandin E1. Bone, 19: 581-588, 1996.
81. Ono, I., Gunji, H., Kaneko, F., Saito, T., and Kuboki, Y., Efficacy of hydroxyapatite ceramic as a carrier for recombinant human bone morphogenetic protein. J. Craniofac. Surg., 6: 238-244, 1995.
82. Ono, I., Gunji, H., Suda, K., Kaneko, F., Murata, M., Saito, T., and Kuboki, Y., Bone induction of hydroxyapatite combined with bone morphogenetic protein and covered with periosteum. Plast. Reconstr. Surg., 95: 1265-1272, 1995.
83. Ono, I., Tateshita, T., and Kuboki, Y., Prostaglandin E1 and recombinant bone morphogenetic protein effect on strength of hydroxyapatite implants. J. Biomed. Mater. Res., 45: 337-344, 1999.
84. Koempel, J.A., Patt, B.S., O’Grady, K., Wozney, J., and Toriumi, D.M., The effect of recombinant human bone morphogenetic protein-2 on the integration of porous hydroxyapatite implants with bone. J. Biomed. Mater. Res., 41: 359-363, 1998.
85. Ruhe, P.Q., Kroese-Deutman, H.C., Wolke, J.G., Spauwen, P.H., and Jansen, J.A., Bone inductive properties of rhBMP-2 loaded porous calcium phosphate cement implants in cranial defects in rabbits. Biomaterials, 25: 2123-2132, 2004.
86. Terheyden, H., Warnke, P., Dunsche, A., Jepsen, S., Brenner, W., Palmie, S., Toth, C., and Rueger, D.R., Mandibular reconstruction with prefabricated vascularized bone grafts using recombinant human osteogenic protein-1: an experimental study in miniature pigs. Part II:transplantation. Int. J. Oral Maxillofac. Surg., 30: 469-478, 2001.
87. Terheyden, H., Knak, C., Jepsen, S., Palmie, S., and Rueger, D.R., Mandibular reconstruction with a prefabricated vascularized bone graft using recombinant human osteogenic protein-1: an experimental study in miniature pigs. Part I: prefabrication. Int. J. Oral Maxillofac. Surg. 30:373-379, 2001.
88. Sumner, D.R., Turner, T.M., Purchio, A.F., Gombotz, W.R., Urban, R.M., and Galante, J.O., Enhancement of bone ingrowth by transforming growth factor-beta. J. Bone Joint Surg. Am. 77:1135-1147, 1995.
89. Meraw, S.J., Reeve, C.M., Lohse, C.M., and Sioussat, T.M., Treatment of peri-implant defects with combination growth factor cement. J. Periodontol., 71: 8-13, 2000.
90. Ripamonti, U., Ramoshebi, L.N., Matsaba, T., Tasker, J., Crooks, J., and Teare, J., Bone induction by BMPs/OPs and related family members in primates. J. Bone Joint Surg. Am. 83-A (Suppl 1):116-127, 2001.
91. Ripamonti, U., Crooks, J., and Rueger, D.C., Induction of bone formation by recombinant human osteogenic protein-1 and sintered porous hydroxyapatite in adult primates. Plast. Reconstr. Surg.107: 977-988, 2001.
92. Boden, S.D., Martin, G.J., Jr., Morone, M.A., Ugbo, J.L., and Moskovitz, P.A., Posterolateral lumbar intertransverse process spine arthrodesis with recombinant human bone morphogenetic protein 2/hydroxyapatite-tricalcium phosphate after laminectomy in the nonhuman primate. Spine, 24: 1179-1185, 1999.
93. Lane, J.M., Tomin, E., and Bostrom, M.P., Biosynthetic bone grafting. Clin. Orthop. 107-117, 1999.
94. Laffargue, P., Fialdes, P., Frayssinet, P., Rtaimate, M., Hildebrand, H.F., and Marchandise, X., Adsorption and release of insulin-like growth factor-I on porous tricalcium phosphate implant. J. Biomed. Mater. Res., 49: 415-421, 2000.
95. Damien, E., Hing, K., Saeed, S., and Revell, P.A., A preliminary study on the enhancement of the osteointegration of a novel synthetic hydroxyapatite scaffold in vivo. J. Biomed. Mater. Res. 66A:241-246, 2003.
96. Ono, I., Tateshita, T., Takita, H., and Kuboki, Y., Promotion of the osteogenetic activity of recombinant human bone morphogenetic protein by basic fibroblast growth factor. J. Craniofac. Surg. 7:418-425, 1996.