Distortion of flavin geometry is linked to ligand binding in cholesterol oxidase

Protein Science

Volumn 16, Issue 12, 2007, Pages 2647-2656

  Lyubimov, Artem Y ^a   Heard, Kathryn ^a   Tang, Hui ^b   Sampson, Nicole S ^b   Vrielink, Alice ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STONY BROOK UNIVERSITY   (United States)

^c UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Cholesterol oxidase; Flavin; Flavin activation; Michaelis complex; Redox potential

Indexed keywords

AROMATIC COMPOUND; BACTERIAL ENZYME; CHOLESTEROL OXIDASE; FLAVINE ADENINE NUCLEOTIDE; GLYCEROL; QUERCETIN;

ARTICLE; BINDING SITE; CATALYSIS; ENZYME STRUCTURE; GEOMETRY; LIGAND BINDING; MICHAELIS CONSTANT; MOLECULAR DYNAMICS; OXIDATION; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; UPREGULATION;

BINDING SITES; CHOLESTEROL OXIDASE; CRYSTALLOGRAPHY, X-RAY; FLAVIN-ADENINE DINUCLEOTIDE; GLYCEROL; LIGANDS; MUTANT PROTEINS; OXIDATION-REDUCTION; STREPTOMYCES;

BACTERIA (MICROORGANISMS);

EID: 36448940092     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.073168207     Document Type: Article

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