Atrial tachycardia induces remodelling of muscarinic receptors and their coupled potassium currents in canine left atrial and pulmonary vein cardiomyocytes

British Journal of Pharmacology

Volumn 152, Issue 7, 2007, Pages 1021-1032

  Yeh, Y H ^a,b,c   Qi, X ^a,b   Shiroshita Takeshita, A ^a,b   Liu, J ^a,b   Maguy, A ^a,b   Chartier, D ^a,b   Hebert, T ^d   Wang, Z ^a,b   Nattel, S ^a,b,d  

^a MONTREAL HEART INSTITUTE   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c CHANG GUNG UNIVERSITY   (Taiwan)

^d MCGILL UNIVERSITY   (Canada)

Author keywords

Atrial fibrillation; Ion channels; Ionic remodelling; M 3 receptor; M 2 receptor; M 4 receptor; Muscarinic acetylcholine receptor (mAChR)

Indexed keywords

4 AMINOPYRIDINE; 4 DIPHENYLACETOXY 1 METHYLPIPERIDINE; ACETYLCHOLINE; CARBACHOL; CHOLINE; MEMBRANE PROTEIN; METHOCTRAMINE; MUSCARINIC M2 RECEPTOR; MUSCARINIC M3 RECEPTOR; MUSCARINIC M4 RECEPTOR; TROPICAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOG; DOWN REGULATION; ELECTROPHYSIOLOGY; HEART ATRIUM FIBRILLATION; HEART LEFT ATRIUM; HEART MUSCLE CELL; HEMODYNAMICS; NONHUMAN; PATCH CLAMP; PATHOPHYSIOLOGY; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PULMONARY VEIN; SUPRAVENTRICULAR TACHYCARDIA; WESTERN BLOTTING;

ANIMALS; ATRIAL FIBRILLATION; BLOTTING, WESTERN; CARDIAC PACING, ARTIFICIAL; CELLS, CULTURED; DISEASE MODELS, ANIMAL; DOGS; DOWN-REGULATION; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; EVOKED POTENTIALS; HEART ATRIA; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PULMONARY VEINS; RECEPTORS, MUSCARINIC; TACHYCARDIA, ECTOPIC ATRIAL; TIME FACTORS;

EID: 36448936117     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0707376     Document Type: Article

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