Characterization of the folding pathway of recombinant human macrophage- colony stimulating-factor β (rhM-CSF β) by bis-cysteinyl modification and mass spectrometry

Proteins: Structure, Function and Genetics

Volumn 33, Issue SUPPL. 2, 1998, Pages 50-62

  Peter Happersberger, H ^a   Stapleton, Janet ^b   Cowgill, Cynthia ^b   Glocker, Michael O ^a  

^a UNIVERSITY OF KONSTANZ   (Germany)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

c fms; Cytokine; ESI MS; Folding intermediates; M CSF; Melarsen oxide; Selective chemical modification; Tryptophan fluorescence

Indexed keywords

CYSTEINE; CYTOKINE; MELARSENOXIDE; RECOMBINANT COLONY STIMULATING FACTOR 1; TRYPTOPHAN;

ANALYTIC METHOD; ARTICLE; COMPUTER ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION REDUCTION REACTION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DENATURATION; PROTEIN FOLDING;

EID: 3643112490     PISSN: 08873585     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0134(1998)33:2+<50::AID-PROT7>3.0.CO;2-R     Document Type: Article

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