Regulation of NO synthesis in endothelial cells

Kidney and Blood Pressure Research

Volumn 21, Issue 2-4, 1998, Pages 264-266

  Busse, Rudi ^a   Fleming, Ingrid ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

Author keywords

Endothelial cells; Nitric oxide synthase; Shear stress

Indexed keywords

CALCIUM ION; MEMBRANE PROTEIN; MESSENGER RNA; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PHOSPHOTYROSINE; PROTEIN TYROSINE KINASE;

COMPLEX FORMATION; CONFERENCE PAPER; ENDOTHELIUM CELL; ENZYME ACTIVITY; MYRISTYLATION; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN STRUCTURE; RNA TRANSCRIPTION; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; ENDOTHELIUM; HUMANS; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE III; TRANSCRIPTION, GENETIC;

EID: 0031786411     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000025872     Document Type: Conference Paper

References (12)

1. Fleming I, Busse R: Vascular effects of NO: in Goligorsky M, Gross SS (eds): Nitric Oxide and the Kidney: Physiology and Pathophysiology. New York, Chapman & Hall, 1997, pp 161-175.
2. Michel T, Feron O: Nitric oxide synthases: Which, where, how and why? J Clin Invest 1997;100:2146-2152.
3. Fleming I, Bauersachs J, Busse R: Calcium-dependent and -independent activation of the endothelial NO synthase. J Vasc Res 1997,34:165-174.
4. Kuchan MJ, Frangos JA: Role of calcium and calmodulin in flow-induced nitric oxide production in endothelial cells Am J Physiol 1994;266:C628-C636.
5. Ayajiki K, Kindermann M, Hecker M, Fleming I, Busse R: Intracellular pH and tyrosine phosphorylation but not calcium determine shear stress-induced nitric oxide production in native endothelial cells. Circ Res 1996;78:750-758
6. Garcia-Cadena G, Fan R, Shah V, Sorrentino R, Cirino G, Papapetropoulos A, Sessa WC: Dynamic activation of endothelial nitric oxide synthase by Hsp90. Nature 1998;292:821-824.
7. Fleming Im Bauersachs J, Fisslthaler B, Busse R: Calcium-independent activation of the endothelial nitric oxide synthase in response to tyrosine phosphatase inhibitors and fluid shear stress. Circ Res 1998;81:686-695.
8. Fleming I, Fisslthaler B, Busse R: Shear stress-induced phosphorylation of the endothelial NO synthase (abstract). Nitric Oxide 1998;2:76.
9. Benzing T, Fleming I, Bouloumié A, Mülsch A, Busse R: Insulin enhances the expression of the constitutive nitric oxide synthase in native porcine aortic endothelial cells via activation or Erk1/2 and AP-1 (abstract). Pflügers Arch 1998;435:R83.
10. Bouloumié A, Schim-Kerth V, Busse R. Vascular endothelial growth factor upregulates nitric oxide synthase expression in cultured and native endothelial cells. Cardiovasc Res 1998; (in press).
11. Yoshizumi M, Perrella MA, Burnett JC Jr, Lee M-E: Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life. Circ Res 1993;73:205-209.
12. Rosenkranz-Weiss P, Sessa WC, Milstien S, Kaufman S, Watson CA, Pober JS: Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells. J Clin Invest 1994;93:2236-2243.