Effect of dexamethasone associated with serum therapy on treatment of Bothrops jararaca venom-induced paw edema in mice

Inflammation Research

Volumn 56, Issue 10, 2007, Pages 409-413

  Araújo, S Dias ^a   De Souza, A ^a   Nunes, F P B ^a   Goncalves L R C ^a  

^a INSTITUTO BUTANTAN   (Brazil)

Author keywords

Anti inflammatory drugs; Bothrops jararaca; Dexamethasone; Edema; Serum therapy

Indexed keywords

BATROXOBIN; DEXAMETHASONE; INDOMETACIN; ZILEUTON;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROL GROUP; CONTROLLED STUDY; DRUG EFFECT; DRUG INHIBITION; FOOT PAD; MALE; MOUSE; NONHUMAN; PAW EDEMA; PLETHYSMOGRAPH; PLETHYSMOGRAPHY;

ANIMALS; ANTIVENINS; BOTHROPS; CROTALID VENOMS; DEXAMETHASONE; EDEMA; MALE; MICE;

EID: 36348987188     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-007-7054-x     Document Type: Article

References (32)

1. Rosenfeld G. Symptomatology, pathology and treatment of snake bites in South America. In: Büchel W, Buckley E (eds.), Venomous animals and their venoms. Vol. 2. New York: Academic Press 1971: 345-84.
2. Cardoso JL, Fan HW, Franca FO, Jorge MT, Leite RP, Nishioka SA et al. Randomized comparative trial of three antivenoms in the treatment of envenoming by lance-headed vipers (Bothrops jararaca) in São Paulo, Brazil. Q J Med 1993; 86: 315-25.
3. França FOS, Málaque CMS. Acidente botrópico. In: Cardoso JLC, França FO, Fan HW, Málaque CMS, Haddad Jr V (eds.), Animais Peçonhentos no Brasil: Biologia, clínica e terapêutica dos acidentes. São Paulo: Sarvier, 2003: 72-86.
4. Warrell DA. The global problem of snake bite: its prevention and treatment. In: Gopalakrishnakone P, Tan CK (eds.), Recent advances in toxinology research. Vol. 1. Singapore: National University of Singapore, 1992: 121-53.
5. Gutiérrez JM, Chaves F, Bolaños R, Cerdas L, Rojas E, Arroyo O et al. Neutralización de los efectos locales del veneno de Bothrops asper por un antiveneno polivalente. Toxicon 1981; 19: 493-500.
6. Picolo G, Chacur M, Gutiérrez JM, Teixeira CF, Cury Y. Evaluation of antivenoms in the neutralization of hyperalgesia and edema induced by Bothrops jararaca and Bothrops asper snake venoms. Braz J Med Biol Res 2002; 35: 1221-8.
7. Trebien HA, Calixto JB. Pharmacological evaluation of rat paw oedema induced by Bothrops jararaca venom. Agents Actions 1989; 26: 292-300.
8. Perales J, Amorim CZ, Rocha SL, Domont GB, Moussatche H. Neutralization of the oedematogenic activity of Bothrops jararaca venom on the mouse paw by an antibothropic fraction isolated from opossum (Didelphis marsupialis) serum. Agents Actions 1992; 37: 250-9.
9. Gonçalves LRC, Mariano M. Local haemorrhage induced by Bothrops jararaca venom: relationship to neurogenic inflammation. Mediators Inflamm 2000; 9: 101-7.
10. Leon G, Rojas G, Lomonte B, Gutiérrez JM. Immunoglobulin G and F(ab')2 polyvalent antivenoms do not differ in their ability to neutralize hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom. Toxicon 1997; 35: 1627-37.
11. Leon G, Valverde JM, Rojas G, Lomonte B, Gutiérrez JM. Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom. Toxicon 2000; 38: 233-44.
12. Perez JC, Sanchez EE. Natural protease inhibitors to hemorrhagins in snake venoms and their potential use in medicine. Toxicon 1999; 37: 703-28.
13. Gutiérrez JM, Léon G, Rojas G, Lomonte B, Rucavado A, Chaves F. Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom. Toxicon 1998; 36: 1529-38.
14. De Faria L, Antunes E, Bon C, De Araújo AL. Pharmacological characterization of the rat paw edema induced by Bothrops lanceolatus (Fer de lance) venom. Toxicon 2001; 39: 825-30.
15. Barbosa AM, Do Amaral RO, Teixeira CFP, Hyslop S, Cogo JC. Pharmacological characterization of mouse hind paw oedema induced by Bothrops insularis (jararaca ilhoa) snake venom. Toxicon 2003; 42: 515-23.
16. Chaves F, Barboza M, Gutierrez JM. Pharmacological Study of Edema Induced by Venom of the Snake Bothrops asper (Terciopelo) in Mice. Toxicon 1995; 33: 31-9.
17. Brazilian Ministry of Health, Manual de diagnóstico e tratamento de acidentes por animais peçonhentos. Fundação Nacional de Saúde, Brasília - DF, 1999.
18. 2. Toxicon 2003; 42: 947-62.
19. Bjarnason JB, Fox JW. Hemorrhagic metalloproteinases from snake venoms. Pharmacol. Ther. 1994; 14: 352-72.
20. Olivo, RA. Teixeira, CFP, Wallace, JL, Gutierrez, JM, Zamuner, SM. Role of cyclooxygenases in oedema-forming activity of bothropic venoms. Toxicon 2007; 49: 670-7.
21. Barnes JP, Adcock I. Anti-inflammatory action of steroids: molecular mechanisms. TIPS 1993; 14: 436-41.
22. Flores CA, Zappellini A, Prado-Franceschi J. Lipoxygenase-derived mediators may be involved in in vivo neutrophil migration induced by Bothrops erythromelas and Bothrops alternatus venom. Toxicon 1993; 31: 1551-9.
23. Chacur M, Picolo G, Gutiérrez JM, Teixeira CPF, Cury Y. Pharmacological modulation of hyperalgesia induced by Bothrops asper (terciopelo) snake venom. Toxicon 2001; 39: 1173-81.
24. Church MK, Miller P. Time courses of the anti-anaphylatic and anti-inflammatory effects of dexamethasone in the rat and mouse. British Journal Pharmacology 1978; 62, 481-6.
25. Tsurufuji S, Kazuo S, Takemasa F. The role of glucocorticoid receptor and gene expression in the anti-inflammatory action of dexamethasone. Nature 1979; 280, 408-10.
26. Coméra C, Russo-Marie F. Glucocortocoid-induced annexin 1 secretion by monocytes and peritoneal leukocytes. British Journal Pharmacology 1995; 115, 1043-7.
27. Zhang WW, Thorlacius H. Dexamethasone inhibits arteriolar leukocyte rolling and adhesion induced by tumor necrosis factor-α in vivo. Inflammation Res. 2000; 49: 95-7.
28. Tailor A, Tomlinson A, Salas A, Panes J, Granger DN, Flowere RJ et al. Dexamethasone inhibition of leukocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC. Gut 1999; 45: 705-12.
29. Petricevich VL, Teixeira CFP, Tambourgi DV, Gutierrez JM. Increments in serum cytokine and nitric oxide levels in mice injected with Bothrops asper and Bothrops jararaca snake venoms. Toxicon 2000; 38: 1253-66.
30. Zamuner SR, Teixeira CFP. Cell adhesion molecules involved in the leukocyte recruitment induced by venom of the snake venom Bothrops jararaca. Mediators of Inflammation 2002; 11: 351-7.
31. Cury Y, Teixeira CFP, Farsky SHP. Lack of effect of endogenous corticosteroids on the acute inflammatory reaction (edema) induced by Bothrops jararaca venom (BjV) in rats. Toxicon 1997; 35: 773-6.
32. Susaki TT, Fan HW, Málaque CMS, Medeiros CR, Cardoso JLC, Ferrari RA et al. Effect of dexamethasone therapy on local edema after Bothrops accidents. Mem. Instituto Butantan 2005; 61: 156.