Fertility and spermatogenesis are altered in α1b-adrenergic receptor knockout male mice

Journal of Endocrinology

Volumn 195, Issue 2, 2007, Pages 281-292

  Mhaouty Kodja, Sakina ^a   Lozach, Anne ^a   Habert, René ^b   Tanneux, Magali ^a   Guigon, Céline ^a   Brailly Tabard, Sylvie ^c   Maltier, Jean Paul ^a   Legrand Maltier, Chantal ^a  

^a CNRS   (France)

^b INSTITUT DE RADIOPROTECTION ET DE SÛRETÉ NUCLÉAIRE   (France)

^c BICÊTRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1B ADRENERGIC RECEPTOR; GONADOTROPIN; INHIBIN A; INHIBIN B; LUTEINIZING HORMONE; MESSENGER RNA; NORADRENALIN; RNA; TESTOSTERONE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL COMMUNICATION; CELL DEATH; CELL FUNCTION; CELL VOLUME; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GENE LOCATION; GERM CELL; HOMEOSTASIS; HOMOZYGOSITY; IN SITU HYBRIDIZATION; IN VITRO STUDY; INCUBATION TIME; KNOCKOUT MOUSE; LEYDIG CELL; LUTEINIZING HORMONE BLOOD LEVEL; MALE; MALE FERTILITY; MALE INFERTILITY; MEIOSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN FUNCTION; SERTOLI CELL; SIGNAL TRANSDUCTION; SPERMATOCYTE; SPERMATOGENESIS; STEROIDOGENESIS; TESTIS FUNCTION; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE RELEASE; WILD TYPE;

ANIMALS; FERTILITY; FOLLICLE STIMULATING HORMONE; HOMOZYGOTE; INFERTILITY, MALE; INHIBINS; LEYDIG CELLS; LUTEINIZING HORMONE; MALE; MICE; MICE, KNOCKOUT; NOREPINEPHRINE; ORGAN SIZE; RECEPTORS, ADRENERGIC, ALPHA-1; RNA; SERTOLI CELLS; SPERMATOCYTES; SPERMATOGENESIS; STEROIDS; TESTIS; TESTOSTERONE; TISSUE DISTRIBUTION;

EID: 36348936123     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/JOE-07-0071     Document Type: Article

References (53)

1. Allan CM, Haywood M, Swarij S, Spaliviero J, Koch A, Jimenez M, Poutanen M, Levallet J, Huhtaniemi I, Illingworth P & Handelsman DJ 2001 A novel transgenic model to characterize the specific effects of follicle-stimulating hormone an gonadal physiology in the absence of luteinizing hormone actions. Endocrinology 142 2213-2220.
2. Anakwe OO & Moger WH 1986 Catecholamine stimulation of androgen production by rat Leydig cells. Interactions with luteinizing hormone and luteinizing hormone-releasing hormone. Biology of Reproduction 35 806-814.
3. Ben-Sasson SA, Sherman Y & Gavrieli Y 1995 Identification of dying cells- in situ staining. In Methods in Cell Biology, 46, Cell Death, pp 29-38. Eds LM Schwartz & BA Osborne. New York: Academic Press.
4. Cavali A, Lattion AL, Hummler E, Nenniger M, Pedrazzini T, Aubert JF, Michel MC, Yang M, Lembo G, Vecchione C et al. 1997 Decreased blood pressure response in mice deficient of alpha 1b-adrenergic receptor. PNAS 94 11589-11594.
5. Chiocchio SR, Suburo AM, Vladucic E, Zhu BC, Charreau E, Decima EE & Tramezzani JH 1999 Diffierential effects of superior and inferior spermatic nerves on testosterone secretion and spermatic blood flow in cats. Endocrinology 140 1036-1043.
6. Chow SH, Giglio W, Anesetti R, Ottenweller JE, Pogach LM & Huang HF 2000 The effects of testicular denervation on spermatogenesis in the Sprague - Dawley rat. Neuroendocrinology 72 37-45.
7. Cooke BA, Golding M, Dix CJ & Hunter MG 1982 Catecholamine stimulation of testosterone production via cyclic AMP in mouse Leydig cells in monolayer culture. Molecular and Cellular Endocrinology 27 221-231.
8. van Dissel-Emiliani FMF, Grootenhuis AJ, de Jong FH & de Rooij DG 1989 Inhibin reduces spermatogonial numbers in testes of adult mice and chinese hamster. Endocrinology 125 1899-1903.
9. Eddy EM, Washburn TF, Bunch DO, Goulding EH, Gladen BC, Lubahn DB & Korach KS 1996 Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility. Endocrinology 137 4796-4805.
10. Eikvar L, Bjornerheim R, Attramadal H & Hansson V 1993 Beta-adrenoceptor mediated responses and subtypes of beta-adrenoceptors in cultured rat Sertoli cells. Journal of Steroid Biochemistry and Molecular Biology 44 85-91.
11. Etgen AM 2003 Ovarian steroid and growth factor regulation of female reproductive function involves modification of hypothalamic α1-adrenoceptor signalling. Annals of the New York Academy of Sciences 1007 153-161.
12. Froment P, Staub C, Hembert S, Pisselet C, Magistrini M, Delaleu B, Seurin D, Levine JE, Johnson L, Binoux M et al. 2004 Reproductive abnormalities in human insulin-like growth factor-binding protein-1 transgenic male mice. Endocrinology 145 2080-2091.
13. Frungieri MB, Urbanski HF, Hohne-Zell B & Mayerhofer A 2000 Neuronal elements in the testis of the rhesus monkey: ontogeny, characterization and relationship to testicular cells. Neuroendocrinology 71 43-50.
14. De Gendt K, Swinnen JV, Saunders PTK, Schoonjans L, Dewerchin M, Devos A, Tan K, Atanassova N, Claessens F, Lécureuil C et al. 2004 A sertoli cell - selective knockout of the androgen receptor causes spermatogenic arrest in meiosis. PNAS 101 1327-1332.
15. Guigon CJ, Mazaud S, Forest MG, Brailly-Tabard S, Coudouel N & Magre S 2003 Unaltered development of the initial follicular waves and normal pubertal onset in female rats after neonatal deletion ofthe follicular reserve. Endocrinology 144 3651-3661
16. Habert R & Picon R 1984 Testosterone, dihydrotestosterone and estradiol-17β levels in maternal and fetal plasma and in fetal testes in the rat. Journal of Steroid Biochemistry 21 193-198.
17. Hayes FJ, Pitteloud N, DeCruz S, Crowley WF, Jr & Boepple PA 2001 Importance of inhibin B in the regulation of FSH secretion in the human male. Journal of Clinical Endocrinology and Metabolism 86 5541-5546.
18. Hellgren I, Sylven C & Magnusson Y 2000 Study of the beta 1 adrenergic receptor expression in human tissues: immunological approach. Biological and Pharmaceutical Bulletin 23 700-703.
19. Hellsten E, Bernard DJ, Owens JW, Eckhaus M, Suchy SF & Nussbaum RL 2002 Sertoli cell vacuolization and abnormal germ cell adhesion in mice deficient in an mositol polyphosphate 5-phosphatase. Biology of Reproduction 66 1522-1530.
20. Hild SA, Reel JR, Larner JM & Blye RP 2001 Disruption of spermatogenesis and Sertoli cell structure and function by the indenopyridine CDB-4022 in rats. Biology of Reproduction 65 1771-1779.
21. Honaramooz A, Behboodi E, Hausler CL, Blash S, Ayres S, Azuma C, Echelard Y & Dobrinski I 2005 Depletion of endogenous germ cells in male pigs and goats in preparation for germ cell transplantation. Journal of Andrology 26 698-705.
22. Keller G, Kennedy M, Papayannopoulou T & Wiles MV 1993 Hematopoietic commitment during embryonic stem cell differentiation in culture. Molecular and Cellular Biology 13 473-486.
23. Kim I, Ariyaratne S & Mendis-Handagama C 2002 Changes in the testis interstitium of Brown Norway rats with aging and effects of luteinizing and thyroid hormones on the aged testes in enhancing the steroidogenic potential. Biology of Reproduction 66 1359-1366.
24. Krishnamurthy H, Danilovicb N, Morales CR & Sairam MR 2000 Qualitative and quantitative decline in spermatogenesis of the follicle-stimulating hormone receptor knockout (FORKO) mouse. Biology of Reproduction 62 1146-1159.
25. Liere P, Akwa Y, Weill-Engerer S, Eychenne B, Pianos A, Robel P, Sjovall J, Schumacher M & Baulieu EE 2000 Validation of an analytical procedure to measure trace amounts of neurosteroids in brain tissue by gas chromatography mass-spectrometry. Journal of Chromatography. B, Biomedical Sciences and Applications 739 301-312.
26. Livera G, Rouiller-Fabre V, Durand P & Habert R 2000 Multiple effects of retinoids on the development of Sertoli, germ, and Leydig cells of fetal and neonatal rat testis in culture. Biology of Reproduction 62 1303-1314.
27. Mayerhofer A, Bartke A & Steger KW 1989 Catecholamine effects on testicular testosterone production in the gonadally active and the gonadally regressed adult golden banister. Biology of Reproduction 40 752-761.
28. Mayerhofer A, Amador AG, Steger RW & Bartke A 1990 Testicular function after local injection of 6-hydroxydopamine or norepinephrine in the golden hamster (Mesocricetus auratus). Journal of Andrology 11 301-311.
29. Mayerhofer A, Frungieri MB, Fritz S, Bulling A, Jessberger B & Vogt HJ 1999 Evidence for catecholaminergic, neuronlike cells in the adult human testis: changes associated with testicular pathologies. Journal of Andrology 20 341-347.
30. Meachem SJ, Nieschlag E & Simoni M 2001 Inbibin B in male reproduction: pathophysiology and clinical relevance. European Journal of Endocrinology 145 561-571.
31. Mhaouty-Kodja S, Houdeau E, Cohen-Tannoudji J & Legrand C 2001 Catecholamines are not linked to myometrial phospholipase C and uterine contraction in late pregnant and parturient mouse. Journal of Physiology 536 123-131.
32. Nagao Y 1989 Viability of meiotic prophase spermatocytes of rats is facilitated in primary culture of dispersed testicular cells on collagen gel by supplementing epinephrine or norepinephrine: evidence that meiotic prophase spermatocytes complete meiotic division in vitro. In Vitro Cellular and Developmental Biology 25 1088-1098.
33. Onoda M, Djakiew D & Papadopoulos V 1991 Pachytene spermatocytes regulate the secretion of Sertoli cell protein(s) which stimulate Leydig cell steroidogenesis. Molecular and Cellular Endocrinology 77 207-216.
34. Papay R, Gaivin R, McCune DF, Rorabaugh BR, Macklin WB, McGrath JC & Perez DM 2004 Mouse alpha 1B-adrenergic receptor is expressed in neurons and NG2 oligodendrocytes. Journal of Comparative Neurology 478 1-10.
35. Prince FP 1992 Ultrastructural evidence of indirect and direct autonomic innervation of human Leydig cells: comparison of neonatal, childhood and pubertal ages. Cell and Tissue Research 269 383-390.
36. Prince FP 1996 Ultrastructural evidence of adrenergic, as well as cholinergic, nerve varicosities in the relation to the lamina propria of the human seminiferous tubules during childhood. Tissue and Cell 28 507-513.
37. Ratnasoorija WD & Wadsworth RM 1990 Impairment of fertility of male rats with prazosin. Contraception 41 441-447.
38. Ratnasoorija WD & Wadsworth RM 1994 Tamsulosin, a selective α1-adrenoceptor antagonist, inhibits fertility of male rats. Andrologia 26 107-110.
39. Robertson KM, O'Donnell L, Jones MEE, Meachern SJ, Boon WC, Fisher CR, Graves KH, McLachlan RI & Simpson ER 1999 Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene. PNAS 96 7986-7991.
40. Rosa-e-Silva AA, Guimaraes MA, Lamano-Carvalho TL & Kempinas WG 1995 Chemical sympathectomy blocks androgen biosynthesis during prepuberty. Brazilian Journal of Medical and Biological Research 28 1109-1112.
41. Roscoe WA, Barr KJ, Mhawi AA, Pomerantz DK & Kidder GM 2001 Failure of spermatogenesis in mice lacking connexin 43. Biology of Reproduction 65 829-838.
42. Russel LD, Ettlin RA, Sinba-Hikim AP & Clegg ED 1990 Staging for specific laboratories species. In Histological and Histopathological Evaluation of the Testis, pp 63-118. Clearwater, Fl: Cache River Press.
43. Saez J & Lejeune H 1996 Regulation of Leydig cell function by hormones and growth factors other than LH and IGF-I. In The Leydig Cell, 1, pp 383-406. Eds A Payne, M Hardy & L Russell. Vienna: Cache River Press
44. Sharpe RM, Turner KJ, McKinnell C, Groome, NP, Atanassova N, Millar MR, Buchanan DL & Cooke PS 1999 Inhibin B levels in plasma of the male rat from birth to adulthood: effect of experimental manipulation of Sertoli cell number. Journal of Andrology 20 94-101.
45. Skinner MK 1991 Cell-cell interactions in the testis. Endocrine Reviews 12 45-77.
46. Tohda A, Matsumiya K, Tadokoro Y, Yomogida K, Miyagawa Y, Dohmae K, Okuyama A & Nishimune Y 2001 Testosterone suppresses spermatogenesis in juvenile spermatogonial depletion (jsd) mice. Biology of Reproduction 65 532-537.
47. Tolszczuk M, Follea N & Pelletier G 1989 Characterization and localization of beta-adrenergic receptors in control and cryptorchidized rat testis by in vitro autoradiography. Journal of Andrology 9 172-177.
48. Tone S, Katoh Y, Fujimoto H, Togashi S, Yanazawa M, Kato Y & Higashinakagawa T 1990 Expression of inhibin α-subunit gene during mouse gametogenesis. Differentiation 44 62-69.
49. Troispoux C, Reiter E, Combarnous Y & Guillou F 1998 β2 adrenergic receptors mediate cAMP, tissue-type plasminogen activator and transferin production in rat Sertoli cells. Molecular and Cellular Endocrinology 142 75-86.
50. Verhoeven G, Dierickx P & de Moor P 1979 Stimulation effect of neurotransmitters on the aromatization of testosterone by Sertoli cell-enriched cultures. Molecular and Cellular Endocrinology 13 241-253.
51. Wanderley MI, Favaretto AL, Valenca MM, Hattori M, Wakabayashi K & Antunes-Rodrigues J 1989 Modulatory effects of adrenergic agonists on testosterone secretion from rat dispersed testicular cells or Percoll-purified Leydig cells. Brazilian Journal of Medical and Biological Research 22 1421-1429.
52. Zhang FP, Pakarainen T, Poutanen M, Toppari J & Huhtaniemi I 2003 The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis. PNAS 100 13692-13697.
53. Zuscik MJ, Sands S, Ross SA, Waugh DJJ, Gaivin RJ, Morilak D & Perez DM 2000 Overexpression of the α1b-adrenergic receptor causes apoptotic neurodegeneraton: multiple system atrophy. Nature Medicine 6 1388-1394.