Modeling dynamic cerebral blood volume changes during brain activation on the basis of the blood-nulled functional MRI signal

NMR in Biomedicine

Volumn 20, Issue 7, 2007, Pages 643-651

  Wu, Changwei W ^a   Liu, Ho Ling ^b   Chen, Jyh Horng ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

Author keywords

Ascular space occupancy; Cerebral blood flow; Cerebral blood volume; Functional magnetic resonance imaging

Indexed keywords

BLOOD; BRAIN; CAPILLARY FLOW; COMPUTER SIMULATION; PHYSIOLOGY;

BLOCH EQUATIONS; CEREBRAL BLOOD VOLUME; FUNCTIONAL MAGNETIC RESONANCE IMAGING; NON-SELECTIVE INVERSION RECOVERY;

MAGNETIC RESONANCE IMAGING;

ARTICLE; BLOOD VOLUME; BRAIN BLOOD FLOW; BRAIN BLOOD VOLUME; BRAIN MAPPING; CAPILLARY; CEREBROSPINAL FLUID FLOW; COMPUTER SIMULATION; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HEMODYNAMICS; HUMAN; INTERMETHOD COMPARISON; INTRAVASCULAR SPACE; MATHEMATICAL ANALYSIS; NERVE CONDUCTION; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STEADY STATE; WATER PERMEABILITY;

ANIMALS; BLOOD VOLUME; CEREBROVASCULAR CIRCULATION; CEREBRUM; COMPUTER SIMULATION; HUMANS; MAGNETIC RESONANCE IMAGING; MODELS, CARDIOVASCULAR;

EID: 36249015436     PISSN: 09523480     EISSN: 10991492     Source Type: Journal    
DOI: 10.1002/nbm.1116     Document Type: Article

References (31)

1. Ogawa S, Menon RS, Tank DW, Kim SG, Merkle H, Ellermann JM, Ugurbil K. Functional brain mapping by blood oxygenation level-dependent contrast magnetic resonance imaging: a comparison of signal characteristics with a biophysical model. Biophys. J. 1993; 64: 803-812.
2. Kim SG, Tsekos NV. Perfusion imaging by a flow-sensitive alternating inversion recovery (FAIR) technique: application to functional brain imaging. Magn. Reson. Med. 1997; 37: 425-435.
3. Mandeville JB, Marota JJA, Kosofsky BE, Keltner JR, Weissleder R, Rosen BR, Welsskoff RM. Dynamic functional imaging of relative cerebral blood volume during rat paw stimulation. Magn. Reson. Med. 1998; 39: 615-624.
4. Hoge RD, Atkinson J, Gill B, Crelier GR, Marrett S, Pike GB. Investigation of BOLD signal dependence on cerebral blood flow and oxygen consumption: the deoxyhemoglobin dilution model. Magn. Reson. Med. 1999; 42: 849-863.
5. Lu H, Golay X, Pekar JJ, van Zijl PC. Functional magnetic resonance imaging based on changes in vascular space occupancy. Magn. Reson. Med. 2003; 50: 263-274.
6. Francis ST, Pears JA, Butterworth S, Bowtell RW, Gowland PA. Measuring the change in CBV upon cortical activation with high temporal resolution using Look-Locker EPI and Gd-DTPA. Magn. Reson. Med. 2003; 50: 483-492.
7. Quirk JD, Bretthorst GL, Duong TQ, Snyder AZ, Springer CS, Ackerman JJH, Neil JJ. Equilibrium water exchange between the intra- and extracellular spaces of mammalian brain. Magn. Reson. Med. 2003; 50: 493-499.
8. Donahue KM, Burstein D, Manning WJ, Gray ML. Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn. Reson. Med. 1994; 32: 66-76.
9. 1H exchange: and estimate of the error introduced in MRI by assuming the fast exchange limit in bolus tracking. Magn. Reson. Med. 2004; 51: 816-827.
10. Kwong KK, Chesler DA, Weisskoff RM, Donahue KM, Davis TL, Østergaard L, Campbell TA, Rosen BR. MR perfusion studies with T1-weighted echo planar imaging. Magn. Reson. Med. 1995; 34: 878-887.
11. Buxton RB, Wong EC, Frank LR. Dynamics of blood flow and oxygenation changes during brain activation: the balloon model. Magn. Reson. Med. 1998; 39: 855-864.
12. Buxton RB. Introduction to Functional Magnetic Resonance Imaging: Principles and Techniques. Cambridge University Press: Cambridge, UK, 2002: 24.
13. 1 weighting. Neuroimage 2002; 17: 943-955.
14. Brooks RA, Di Chiro G. Magnetic resonance imaging of stationary blood: a review. Med. Phys. 1987; 14: 903-913.
15. Detre JA, Leigh JS, Williams DS, Koretsky AP. Perfusion imaging. Magn. Reson. Med. 1992; 23: 37-45.
16. Williams DS, Detre JA, Leigh JS, Koretsky AP. Magnetic resonance imaging of perfusion using spin inversion of arterial water. Proc. Natl. Acad. Sci. USA. 1992; 89: 212-216.
17. Kim SG. Quantification of relative cerebral blood flow change by flow-sensitive alternating inversion recovery (FAIR) technique: application to functional mapping. Magn. Reson. Med. 1995; 34: 293-301.
18. Leenders K, Perani D, Lammertsma A, Heather J, Buckingham P, Healy M, Gibbs J, Wise R, Hatazawa J, Herold S, Beaney R, Brooks D, Spinks T, Rhodes C, Frackowiak R, Jones T. Cerebral blood flow, blood volume and oxygen utilization: normal values and effect of age. Brain 1990; 113: 27-47.
19. aCO2 on cerebral blood volume, blood flow, and vascular mean transit time. Stroke 1974; 5: 630-639.
20. Hazlewood C, Chang D, Nichols B, Woessner DE. Nuclear magnetic resonance transverse relaxation times of water in skeletal muscle. Biophys. J. 1974; 14: 583-605.
21. Lawrence K, Ye F. Effects of water exchange and venous outflow on VASO contrast: a theoretical study. Proc. 13th Annual Meeting ISMRM, Miami, FL, 2005: 1418.
22. Seitz DJ, Roland PE. Vibratory stimulation increases and decreases the regional cerebral blood flow and oxidative metabolism: a positron emission tomography (PET) study. Acta. Neurol. Scand. 1992; 86: 60-67.
23. Grafton ST. PET: activation of cerebral blood flow and glucose metabolism. Adv. Neurol. 2000; 83: 87-103.
24. 2 change estimated by fMRI. Proc. 11th Annual Meeting ISMRM, Toronto, Canada, 2003: 1805.
25. Mandeville JB, Marota JA, Ayata C, Zaharchuk G, Moskowitz MA, Rosen BR, Weisskoff RM. Evidence of a cerebrovascular postarteriole Windkessel with delayed compliance. J. Cereb. Blood Flow Metab. 1999; 19: 679-689.
26. Wu G, Luo F, Li Z, Zhao X, Li SJ. Transient relationships among BOLD, CBV, and CBF changes in rat brain as detected by functional MRI. Magn. Reson. Med. 2002; 48: 987-993.
27. Kida I, Hyder F. The relationship between changes in CBF and CBV is dynamically varying throughout stimulus duration but complex following stimulus offset. Proc. 12th Annual Meeting ISMRM, Kyoto, Japan, 2004: 1008.
28. Lu H, Golay X, Pekar JJ, Van Zijl PC. Sustained poststimulus elevation in cerebral oxygen utilization after vascular recovery. J. Cereb. Blood Flow Metab. 2004; 19: 764-770.
29. Donahue MJ, Lu H, Jones CK, Pekar JJ, Van Zijl PC. An investigation of the VASO contrast mechanism reveals a novel method for quantifying cerebral blood flow. Proc. 14th Annual Meeting ISMRM, Seatle, WA, 2006: 2769.
30. Belliveau JW, Kennedy DN Jr, McKinstry RC, Buchbinder BR, Weisskoff RM, Cohen MS, Vevea JM, Brady TJ, Rosen BR. Functional mapping of the human visual cortex by magnetic resonance imaging. Science 1991; 254(5032): 716-719.
31. Duck FA. Nuclear Magnetism of Tissue, Academic Press: London, 1990; 279-317.