메뉴 건너뛰기




Volumn 3, Issue 1, 2007, Pages 23-28

Synthetic RNA circuits

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; COCARBOXYLASE; COMPLEMENTARY RNA; DEOXYRIBOZYME; MESSENGER RNA; MICRORNA; NUCLEIC ACID; NUCLEOTIDE; RIBOZYME; RNA; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; SMALL NUCLEOLAR RNA; VIRUS PROTEIN;

EID: 33845735891     PISSN: 15524450     EISSN: 15524469     Source Type: Journal    
DOI: 10.1038/nchembio846     Document Type: Review
Times cited : (47)

References (82)
  • 1
    • 33745899048 scopus 로고    scopus 로고
    • Alternative splicing: New insights from global analyses
    • Blencowe, B.J. Alternative splicing: new insights from global analyses. Cell 126, 37-47 (2006).
    • (2006) Cell , vol.126 , pp. 37-47
    • Blencowe, B.J.1
  • 2
    • 0035984639 scopus 로고    scopus 로고
    • Regulation by transcription attenuation in bacteria: How RNA provides instructions for transcription termination/antitermination decisions
    • Henkin, T.M. & Yanofsky, C. Regulation by transcription attenuation in bacteria: how RNA provides instructions for transcription termination/antitermination decisions. Bioessays 24, 700-707 (2002).
    • (2002) Bioessays , vol.24 , pp. 700-707
    • Henkin, T.M.1    Yanofsky, C.2
  • 3
    • 0035912793 scopus 로고    scopus 로고
    • Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome
    • Keene, J.D. Ribonucleoprotein infrastructure regulating the flow of genetic information between the genome and the proteome. Proc. Natl. Acad. Sci. USA 98, 7018-7024 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 7018-7024
    • Keene, J.D.1
  • 4
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis, B.P., Burge, C.B. & Bartel, D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120, 15-20 (2005).
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 5
    • 36849148382 scopus 로고
    • Origin of life: The RNA world
    • Gilbert, W. Origin of life: the RNA world. Nature 319, 618 (1986).
    • (1986) Nature , vol.319 , pp. 618
    • Gilbert, W.1
  • 6
    • 33745577150 scopus 로고    scopus 로고
    • A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep
    • Clop, A. et al. A mutation creating a potential illegitimate microRNA target site in the myostatin gene affects muscularity in sheep. Nat. Genet. 38, 813-818 (2006).
    • (2006) Nat. Genet. , vol.38 , pp. 813-818
    • Clop, A.1
  • 7
    • 1942435249 scopus 로고    scopus 로고
    • Micromanagers of gene expression: The potentially widespread influence of metazoan microRNAs
    • Bartel, D.P. & Chen, C.Z. Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat. Rev. Genet. 5, 396-400 (2004).
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 396-400
    • Bartel, D.P.1    Chen, C.Z.2
  • 8
    • 84984765621 scopus 로고    scopus 로고
    • Canalization of development by microRNAs
    • Hornstein, E. & Shomron, N. Canalization of development by microRNAs. Nat. Genet. 38 (suppl.), 20-24 (2006).
    • (2006) Nat. Genet. , vol.38 , Issue.SUPPL. , pp. 20-24
    • Hornstein, E.1    Shomron, N.2
  • 9
    • 0024211331 scopus 로고
    • Antisense RNA: Its functions and applications in gene regulation-a review
    • Inouye, M. Antisense RNA: its functions and applications in gene regulation-a review. Gene 72, 25-34 (1988).
    • (1988) Gene , vol.72 , pp. 25-34
    • Inouye, M.1
  • 10
    • 33750991861 scopus 로고    scopus 로고
    • The potential of oligonucleotides for therapeutic applications
    • Fichou, Y. & Ferec, C. The potential of oligonucleotides for therapeutic applications. Trends Biotechnol. 24, 563-570 (2006).
    • (2006) Trends Biotechnol. , vol.24 , pp. 563-570
    • Fichou, Y.1    Ferec, C.2
  • 11
    • 33645148088 scopus 로고    scopus 로고
    • The silent treatment: siRNAs as small molecule drugs
    • Dykxhoorn, D.M., Palliser, D. & Lieberman, J. The silent treatment: siRNAs as small molecule drugs. Gene Ther. 13, 541-552 (2006).
    • (2006) Gene Ther. , vol.13 , pp. 541-552
    • Dykxhoorn, D.M.1    Palliser, D.2    Lieberman, J.3
  • 12
    • 10944254152 scopus 로고    scopus 로고
    • Transcription and processing of human microRNA precursors
    • Cullen, B.R. Transcription and processing of human microRNA precursors. Mol. Cell 16, 861-865 (2004).
    • (2004) Mol. Cell , vol.16 , pp. 861-865
    • Cullen, B.R.1
  • 13
    • 0034625237 scopus 로고    scopus 로고
    • 6S RNA regulates E. coli RNA polymerase activity
    • Wassarman, K.M. & Storz, G. 6S RNA regulates E. coli RNA polymerase activity. Cell 101, 613-623 (2000).
    • (2000) Cell , vol.101 , pp. 613-623
    • Wassarman, K.M.1    Storz, G.2
  • 14
    • 4344579113 scopus 로고    scopus 로고
    • The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock
    • Allen, T.A., Von Kaenel, S., Goodrich, J.A. & Kugel, J.F. The SINE-encoded mouse B2 RNA represses mRNA transcription in response to heat shock. Nat. Struct. Mol. Biol. 11, 816-821 (2004).
    • (2004) Nat. Struct. Mol. Biol. , vol.11 , pp. 816-821
    • Allen, T.A.1    Von Kaenel, S.2    Goodrich, J.A.3    Kugel, J.F.4
  • 16
    • 1842298127 scopus 로고    scopus 로고
    • Selective targeting and inhibition of yeast RNA polymerase II by RNA aptamers
    • Thomas, M. et al. Selective targeting and inhibition of yeast RNA polymerase II by RNA aptamers. J. Biol. Chem. 272, 27980-27986 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 27980-27986
    • Thomas, M.1
  • 17
    • 30044449636 scopus 로고    scopus 로고
    • Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs
    • Kettenberger, H. et al. Structure of an RNA polymerase II-RNA inhibitor complex elucidates transcription regulation by noncoding RNAs. Nat. Struct. Mol. Biol. 13, 44-48 (2006).
    • (2006) Nat. Struct. Mol. Biol. , vol.13 , pp. 44-48
    • Kettenberger, H.1
  • 19
  • 20
    • 0346882677 scopus 로고    scopus 로고
    • Anti-HIV inhibitors based on nucleic acids: Emergence of aptamers as potent antivirals
    • Joshi, P.J., Fisher, T.S. & Prasad, V.R. Anti-HIV inhibitors based on nucleic acids: emergence of aptamers as potent antivirals. Curr. Drug Targets Infect. Disord. 3, 383-400 (2003).
    • (2003) Curr. Drug Targets Infect. Disord. , vol.3 , pp. 383-400
    • Joshi, P.J.1    Fisher, T.S.2    Prasad, V.R.3
  • 23
    • 0037206833 scopus 로고    scopus 로고
    • Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression
    • Winkler, W., Nahvi, A. & Breaker, R.R. Thiamine derivatives bind messenger RNAs directly to regulate bacterial gene expression. Nature 419, 952-956 (2002).
    • (2002) Nature , vol.419 , pp. 952-956
    • Winkler, W.1    Nahvi, A.2    Breaker, R.R.3
  • 24
    • 18744396047 scopus 로고    scopus 로고
    • Sensing small molecules by nascent RNA: A mechanism to control transcription in bacteria
    • Mironov, A.S. et al. Sensing small molecules by nascent RNA: a mechanism to control transcription in bacteria. Cell 111, 747-756 (2002).
    • (2002) Cell , vol.111 , pp. 747-756
    • Mironov, A.S.1
  • 25
    • 33744469562 scopus 로고    scopus 로고
    • Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand
    • Thore, S., Leibundgut, M. & Ban, N. Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand. Science 312, 1208-1211 (2006).
    • (2006) Science , vol.312 , pp. 1208-1211
    • Thore, S.1    Leibundgut, M.2    Ban, N.3
  • 26
    • 33745635350 scopus 로고    scopus 로고
    • Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch
    • Serganov, A., Polonskaia, A., Phan, A.T., Breaker, R.R. & Patel, D.J. Structural basis for gene regulation by a thiamine pyrophosphate-sensing riboswitch. Nature 441, 1167-1171 (2006).
    • (2006) Nature , vol.441 , pp. 1167-1171
    • Serganov, A.1    Polonskaia, A.2    Phan, A.T.3    Breaker, R.R.4    Patel, D.J.5
  • 27
    • 33749986680 scopus 로고    scopus 로고
    • Tandem riboswitch architectures exhibit complex gene control functions
    • Sudarsan, N. et al. Tandem riboswitch architectures exhibit complex gene control functions. Science 314, 300-304 (2006).
    • (2006) Science , vol.314 , pp. 300-304
    • Sudarsan, N.1
  • 28
    • 5044234799 scopus 로고    scopus 로고
    • A glycine-dependent riboswitch that uses cooperative binding to control gene expression
    • Mandal, M. et al. A glycine-dependent riboswitch that uses cooperative binding to control gene expression. Science 306, 275-279 (2004).
    • (2004) Science , vol.306 , pp. 275-279
    • Mandal, M.1
  • 29
    • 27144527479 scopus 로고    scopus 로고
    • Regulation of bacterial gene expression by riboswitches
    • Winkler, W.C. & Breaker, R.R. Regulation of bacterial gene expression by riboswitches. Annu. Rev. Microbiol. 59, 487-517 (2005).
    • (2005) Annu. Rev. Microbiol. , vol.59 , pp. 487-517
    • Winkler, W.C.1    Breaker, R.R.2
  • 30
    • 0038136962 scopus 로고    scopus 로고
    • Metabolite-binding RNA domains are present in the genes of eukaryotes
    • Sudarsan, N., Barrick, J.E. & Breaker, R.R. Metabolite-binding RNA domains are present in the genes of eukaryotes. RNA 9, 644-647 (2003).
    • (2003) RNA , vol.9 , pp. 644-647
    • Sudarsan, N.1    Barrick, J.E.2    Breaker, R.R.3
  • 31
    • 0346366823 scopus 로고    scopus 로고
    • Thiamine-regulated gene expression of Aspergillus oryzae thiA requires splicing of the intron containing a riboswitch-like domain in the 5′-UTR
    • Kubodera, T. et al. Thiamine-regulated gene expression of Aspergillus oryzae thiA requires splicing of the intron containing a riboswitch-like domain in the 5′-UTR. FEBS Lett. 555, 516-520 (2003).
    • (2003) FEBS Lett. , vol.555 , pp. 516-520
    • Kubodera, T.1
  • 32
    • 20444441572 scopus 로고    scopus 로고
    • Ribozyme catalysis: Not different, just worse
    • Doudna, J.A. & Lorsch, J.R. Ribozyme catalysis: not different, just worse. Nat. Struct. Mol. Biol. 12, 395-402 (2005).
    • (2005) Nat. Struct. Mol. Biol. , vol.12 , pp. 395-402
    • Doudna, J.A.1    Lorsch, J.R.2
  • 33
    • 1642586299 scopus 로고    scopus 로고
    • Control of gene expression by a natural metabolite-responsive ribozyme
    • Winkler, W.C., Nahvi, A., Roth, A., Collins, J.A. & Breaker, R.R. Control of gene expression by a natural metabolite-responsive ribozyme. Nature 428, 281-286 (2004).
    • (2004) Nature , vol.428 , pp. 281-286
    • Winkler, W.C.1    Nahvi, A.2    Roth, A.3    Collins, J.A.4    Breaker, R.R.5
  • 34
    • 9644270488 scopus 로고    scopus 로고
    • Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination
    • Teixeira, A. et al. Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination. Nature 432, 526-530 (2004).
    • (2004) Nature , vol.432 , pp. 526-530
    • Teixeira, A.1
  • 35
    • 33749034196 scopus 로고    scopus 로고
    • A genomewide search for ribozymes reveals an HDV-like sequence in the human CPEB3 gene
    • Salehi-Ashtiani, K., Luptak, A., Litovchick, A. & Szostak, J.W. A genomewide search for ribozymes reveals an HDV-like sequence in the human CPEB3 gene. Science 313, 1788-1792 (2006).
    • (2006) Science , vol.313 , pp. 1788-1792
    • Salehi-Ashtiani, K.1    Luptak, A.2    Litovchick, A.3    Szostak, J.W.4
  • 36
    • 32644439149 scopus 로고    scopus 로고
    • Functional hammerhead ribozymes naturally encoded in the genome of Arabidopsis thaliana
    • Przybilski, R. et al. Functional hammerhead ribozymes naturally encoded in the genome of Arabidopsis thaliana. Plant Cell 17, 1877-1885 (2005).
    • (2005) Plant Cell , vol.17 , pp. 1877-1885
    • Przybilski, R.1
  • 38
    • 0033616774 scopus 로고    scopus 로고
    • Engineering precision RNA molecular switches
    • Soukup, G.A. & Breaker, R.R. Engineering precision RNA molecular switches. Proc. Natl. Acad. Sci. USA 96, 3584-3589 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 3584-3589
    • Soukup, G.A.1    Breaker, R.R.2
  • 39
    • 0032955410 scopus 로고    scopus 로고
    • In vitro selection of an allosteric ribozyme that transduces analytes to amplicons
    • Robertson, M.P. & Ellington, A.D. In vitro selection of an allosteric ribozyme that transduces analytes to amplicons. Nat. Biotechnol. 17, 62-66 (1999).
    • (1999) Nat. Biotechnol. , vol.17 , pp. 62-66
    • Robertson, M.P.1    Ellington, A.D.2
  • 40
    • 0034936573 scopus 로고    scopus 로고
    • In vitro selection of nucleoprotein enzymes
    • Robertson, M.P. & Ellington, A.D. In vitro selection of nucleoprotein enzymes. Nat. Biotechnol. 19, 650-655 (2001).
    • (2001) Nat. Biotechnol. , vol.19 , pp. 650-655
    • Robertson, M.P.1    Ellington, A.D.2
  • 41
    • 0036022522 scopus 로고    scopus 로고
    • Monitoring post-translational modification of proteins with allosteric ribozymes
    • Vaish, N.K. et al. Monitoring post-translational modification of proteins with allosteric ribozymes. Nat. Biotechnol. 20, 810-815 (2002).
    • (2002) Nat. Biotechnol. , vol.20 , pp. 810-815
    • Vaish, N.K.1
  • 42
    • 0035476680 scopus 로고    scopus 로고
    • Design and development of a catalytic ribonucleoprotein
    • Atsumi, S., Ikawa, Y., Shiraishi, H. & Inoue, T. Design and development of a catalytic ribonucleoprotein. EMBO J. 20, 5453-5460 (2001).
    • (2001) EMBO J. , vol.20 , pp. 5453-5460
    • Atsumi, S.1    Ikawa, Y.2    Shiraishi, H.3    Inoue, T.4
  • 43
    • 0035989643 scopus 로고    scopus 로고
    • Protein-dependent ribozymes report molecular interactions in real time
    • Hartig, J.S. et al. Protein-dependent ribozymes report molecular interactions in real time. Nat. Biotechnol. 20, 717-722 (2002).
    • (2002) Nat. Biotechnol. , vol.20 , pp. 717-722
    • Hartig, J.S.1
  • 44
    • 0346992203 scopus 로고    scopus 로고
    • In vitro selection of ribozymes dependent on peptides for activity
    • Robertson, M.P., Knudsen, S.M. & Ellington, A.D. In vitro selection of ribozymes dependent on peptides for activity. RNA 10, 114-127 (2004).
    • (2004) RNA , vol.10 , pp. 114-127
    • Robertson, M.P.1    Knudsen, S.M.2    Ellington, A.D.3
  • 45
    • 2942670347 scopus 로고    scopus 로고
    • Sensing complex regulatory networks by conformationally controlled hairpin ribozymes
    • Najafi-Shoushtari, S.H., Mayer, G. & Famulok, M. Sensing complex regulatory networks by conformationally controlled hairpin ribozymes. Nucleic Acids Res. 32, 3212-3219 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , pp. 3212-3219
    • Najafi-Shoushtari, S.H.1    Mayer, G.2    Famulok, M.3
  • 46
    • 0036469778 scopus 로고    scopus 로고
    • Engineered allosteric ribozymes as biosensor components
    • Breaker, R.R. Engineered allosteric ribozymes as biosensor components. Curr. Opin. Biotechnol. 13, 31-39 (2002).
    • (2002) Curr. Opin. Biotechnol. , vol.13 , pp. 31-39
    • Breaker, R.R.1
  • 47
    • 27144550160 scopus 로고    scopus 로고
    • Arming antibodies: Prospects and challenges for immunoconjugates
    • Wu, A.M. & Senter, P.D. Arming antibodies: prospects and challenges for immunoconjugates. Nat. Biotechnol. 23, 1137-1146 (2005).
    • (2005) Nat. Biotechnol. , vol.23 , pp. 1137-1146
    • Wu, A.M.1    Senter, P.D.2
  • 48
    • 0344690107 scopus 로고    scopus 로고
    • Combinatorial selection of high affinity RNA ligands to live African trypanosomes
    • Homann, M. & Goringer, H.U. Combinatorial selection of high affinity RNA ligands to live African trypanosomes. Nucleic Acids Res. 27, 2006-2014 (1999).
    • (1999) Nucleic Acids Res. , vol.27 , pp. 2006-2014
    • Homann, M.1    Goringer, H.U.2
  • 49
    • 33747053632 scopus 로고    scopus 로고
    • Aptamers evolved from live cells as effective molecular probes for cancer study
    • Shangguan, D. et al. Aptamers evolved from live cells as effective molecular probes for cancer study. Proc. Natl. Acad. Sci. USA 103, 11838-11843 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 11838-11843
    • Shangguan, D.1
  • 50
    • 0037099536 scopus 로고    scopus 로고
    • Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
    • Lupold, S.E., Hicke, B.J., Lin, Y. & Coffey, D.S. Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen. Cancer Res. 62, 4029-4033 (2002).
    • (2002) Cancer Res. , vol.62 , pp. 4029-4033
    • Lupold, S.E.1    Hicke, B.J.2    Lin, Y.3    Coffey, D.S.4
  • 51
    • 33745714275 scopus 로고    scopus 로고
    • Aptamer:toxin conjugates that specifically target prostate tumor cells
    • Chu, T.C. et al. Aptamer:toxin conjugates that specifically target prostate tumor cells. Cancer Res. 66, 5989-5992 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 5989-5992
    • Chu, T.C.1
  • 52
    • 7444223607 scopus 로고    scopus 로고
    • Nanoparticle-aptamer bioconjugates: A new approach for targeting prostate cancer cells
    • Farokhzad, O.C. et al. Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res. 64, 7668-7672 (2004).
    • (2004) Cancer Res. , vol.64 , pp. 7668-7672
    • Farokhzad, O.C.1
  • 53
    • 33646582037 scopus 로고    scopus 로고
    • Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo
    • Farokhzad, O.C. et al. Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc. Natl. Acad. Sci. USA 103, 6315-6320 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 6315-6320
    • Farokhzad, O.C.1
  • 55
    • 33747031960 scopus 로고    scopus 로고
    • Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras
    • McNamara, J.O., II et al. Cell type-specific delivery of siRNAs with aptamer-siRNA chimeras. Nat. Biotechnol. 24, 1005-1015 (2006).
    • (2006) Nat. Biotechnol. , vol.24 , pp. 1005-1015
    • McNamara II, J.O.1
  • 56
    • 0032500736 scopus 로고    scopus 로고
    • Controlling gene expression in living cells through small molecule-RNA interactions
    • Werstuck, G. & Green, M.R. Controlling gene expression in living cells through small molecule-RNA interactions. Science 282, 296-298 (1998).
    • (1998) Science , vol.282 , pp. 296-298
    • Werstuck, G.1    Green, M.R.2
  • 57
    • 0034845858 scopus 로고    scopus 로고
    • Inducible regulation of the S. cerevisiae cell cycle mediated by an RNA aptamer-ligand complex
    • Grate, D. & Wilson, C. Inducible regulation of the S. cerevisiae cell cycle mediated by an RNA aptamer-ligand complex. Bioorg. Med. Chem. 9, 2565-2570 (2001).
    • (2001) Bioorg. Med. Chem. , vol.9 , pp. 2565-2570
    • Grate, D.1    Wilson, C.2
  • 58
    • 0036235684 scopus 로고    scopus 로고
    • Inhibition of translation by RNA-small molecule interactions
    • Harvey, I., Garneau, P. & Pelletier, J. Inhibition of translation by RNA-small molecule interactions. RNA 8, 452-463 (2002).
    • (2002) RNA , vol.8 , pp. 452-463
    • Harvey, I.1    Garneau, P.2    Pelletier, J.3
  • 59
    • 15444379109 scopus 로고    scopus 로고
    • Molecular analysis of a synthetic tetracycline-binding riboswitch
    • Hanson, S., Bauer, G., Fink, B. & Suess, B. Molecular analysis of a synthetic tetracycline-binding riboswitch. RNA 11, 503-511 (2005).
    • (2005) RNA , vol.11 , pp. 503-511
    • Hanson, S.1    Bauer, G.2    Fink, B.3    Suess, B.4
  • 60
    • 0037388001 scopus 로고    scopus 로고
    • Conditional gene expression by controlling translation with tetracycline-binding aptamers
    • Suess, B. et al. Conditional gene expression by controlling translation with tetracycline-binding aptamers. Nucleic Acids Res. 31, 1853-1858 (2003).
    • (2003) Nucleic Acids Res. , vol.31 , pp. 1853-1858
    • Suess, B.1
  • 61
    • 0141677751 scopus 로고    scopus 로고
    • Tetracycline-aptamer-mediated translational regulation in yeast
    • Hanson, S., Berthelot, K., Fink, B., McCarthy, J.E. & Suess, B. Tetracycline-aptamer-mediated translational regulation in yeast. Mol. Microbiol. 49, 1627-1637 (2003).
    • (2003) Mol. Microbiol. , vol.49 , pp. 1627-1637
    • Hanson, S.1    Berthelot, K.2    Fink, B.3    McCarthy, J.E.4    Suess, B.5
  • 62
    • 27144526390 scopus 로고    scopus 로고
    • An artificial riboswitch for controlling pre-mRNA splicing
    • Kim, D.S., Gusti, V., Pillai, S.G. & Gaur, R.K. An artificial riboswitch for controlling pre-mRNA splicing. RNA 11, 1667-1677 (2005).
    • (2005) RNA , vol.11 , pp. 1667-1677
    • Kim, D.S.1    Gusti, V.2    Pillai, S.G.3    Gaur, R.K.4
  • 63
    • 2542601538 scopus 로고    scopus 로고
    • A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo
    • Suess, B., Fink, B., Berens, C., Stentz, R. & Hillen, W. A theophylline responsive riboswitch based on helix slipping controls gene expression in vivo. Nucleic Acids Res. 32, 1610-1614 (2004).
    • (2004) Nucleic Acids Res. , vol.32 , pp. 1610-1614
    • Suess, B.1    Fink, B.2    Berens, C.3    Stentz, R.4    Hillen, W.5
  • 64
    • 6044261460 scopus 로고    scopus 로고
    • Genetic screens and selections for small molecules based on a synthetic riboswitch that activates protein translation
    • Desai, S.K. & Gallivan, J.P. Genetic screens and selections for small molecules based on a synthetic riboswitch that activates protein translation. J. Am. Chem. Soc. 126, 13247-13254 (2004).
    • (2004) J. Am. Chem. Soc. , vol.126 , pp. 13247-13254
    • Desai, S.K.1    Gallivan, J.P.2
  • 65
    • 0036849338 scopus 로고    scopus 로고
    • A versatile communication module for controlling RNA folding and catalysis
    • Kertsburg, A. & Soukup, G.A. A versatile communication module for controlling RNA folding and catalysis. Nucleic Acids Res. 30, 4599-4606 (2002).
    • (2002) Nucleic Acids Res. , vol.30 , pp. 4599-4606
    • Kertsburg, A.1    Soukup, G.A.2
  • 67
    • 4644275337 scopus 로고    scopus 로고
    • Exogenous control of mammalian gene expression through modulation of RNA self-cleavage
    • Yen, L. et al. Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature 431, 471-476 (2004).
    • (2004) Nature , vol.431 , pp. 471-476
    • Yen, L.1
  • 68
    • 33646192489 scopus 로고    scopus 로고
    • Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries
    • Yen, L., Magnier, M., Weissleder, R., Stockwell, B.R. & Mulligan, R.C. Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA 12, 797-806 (2006).
    • (2006) RNA , vol.12 , pp. 797-806
    • Yen, L.1    Magnier, M.2    Weissleder, R.3    Stockwell, B.R.4    Mulligan, R.C.5
  • 69
    • 3042741121 scopus 로고    scopus 로고
    • Engineered riboregulators enable post-transcriptional control of gene expression
    • Isaacs, F.J. et al. Engineered riboregulators enable post-transcriptional control of gene expression. Nat. Biotechnol. 22, 841-847 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 841-847
    • Isaacs, F.J.1
  • 70
    • 0032514643 scopus 로고    scopus 로고
    • Riboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple loci
    • Lease, R.A., Cusick, M.E. & Belfort, M. Riboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple loci. Proc. Natl. Acad. Sci. USA 95, 12456-12461 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12456-12461
    • Lease, R.A.1    Cusick, M.E.2    Belfort, M.3
  • 71
    • 21444457242 scopus 로고    scopus 로고
    • Programmable ligand-controlled riboregulators of eukaryotic gene expression
    • Bayer, T.S. & Smolke, C.D. Programmable ligand-controlled riboregulators of eukaryotic gene expression. Nat. Biotechnol. 23, 337-343 (2005).
    • (2005) Nat. Biotechnol. , vol.23 , pp. 337-343
    • Bayer, T.S.1    Smolke, C.D.2
  • 72
    • 33646183047 scopus 로고    scopus 로고
    • Artificial control of gene expression in mammalian cells by modulating RNA interference through aptamer-small molecule interaction
    • An, C.I., Trinh, V.B. & Yokobayashi, Y. Artificial control of gene expression in mammalian cells by modulating RNA interference through aptamer-small molecule interaction. RNA 12, 710-716 (2006).
    • (2006) RNA , vol.12 , pp. 710-716
    • An, C.I.1    Trinh, V.B.2    Yokobayashi, Y.3
  • 73
    • 0029776689 scopus 로고    scopus 로고
    • A three-hybrid system to detect RNA-protein interactions in vivo
    • SenGupta, D.J. et al. A three-hybrid system to detect RNA-protein interactions in vivo. Proc. Natl. Acad. Sci. USA 93, 8496-8501 (1996).
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 8496-8501
    • SenGupta, D.J.1
  • 74
    • 0032900053 scopus 로고    scopus 로고
    • Identification of RNAs that bind to a specific protein using the yeast three-hybrid system
    • Sengupta, D.J., Wickens, M. & Fields, S. Identification of RNAs that bind to a specific protein using the yeast three-hybrid system. RNA 5, 596-601 (1999).
    • (1999) RNA , vol.5 , pp. 596-601
    • Sengupta, D.J.1    Wickens, M.2    Fields, S.3
  • 75
    • 0037337009 scopus 로고    scopus 로고
    • RNA sequences that work as transcriptional activating regions
    • Saha, S., Ansari, A.Z., Jarrell, K.A. & Ptashne, M. RNA sequences that work as transcriptional activating regions. Nucleic Acids Res. 31, 1565-1570 (2003).
    • (2003) Nucleic Acids Res. , vol.31 , pp. 1565-1570
    • Saha, S.1    Ansari, A.Z.2    Jarrell, K.A.3    Ptashne, M.4
  • 76
    • 0037863216 scopus 로고    scopus 로고
    • In vivo evolution of an RNA-based transcriptional activator
    • Buskirk, A.R., Kehayova, P.D., Landrigan, A. & Liu, D.R. In vivo evolution of an RNA-based transcriptional activator. Chem. Biol. 10, 533-540 (2003).
    • (2003) Chem. Biol. , vol.10 , pp. 533-540
    • Buskirk, A.R.1    Kehayova, P.D.2    Landrigan, A.3    Liu, D.R.4
  • 77
    • 4344646564 scopus 로고    scopus 로고
    • Engineering a ligand-dependent RNA transcriptional activator
    • Buskirk, A.R., Landrigan, A. & Liu, D.R. Engineering a ligand-dependent RNA transcriptional activator. Chem. Biol. 11, 1157-1163 (2004).
    • (2004) Chem. Biol. , vol.11 , pp. 1157-1163
    • Buskirk, A.R.1    Landrigan, A.2    Liu, D.R.3
  • 78
    • 0034688173 scopus 로고    scopus 로고
    • A synthetic oscillatory network of transcriptional regulators
    • Elowitz, M.B. & Leibler, S. A synthetic oscillatory network of transcriptional regulators. Nature 403, 335-338 (2000).
    • (2000) Nature , vol.403 , pp. 335-338
    • Elowitz, M.B.1    Leibler, S.2
  • 79
    • 0034688174 scopus 로고    scopus 로고
    • Construction of a genetic toggle switch in Escherichia coli
    • Gardner, T.S., Cantor, C.R. & Collins, J.J. Construction of a genetic toggle switch in Escherichia coli. Nature 403, 339-342 (2000).
    • (2000) Nature , vol.403 , pp. 339-342
    • Gardner, T.S.1    Cantor, C.R.2    Collins, J.J.3
  • 80
    • 28544442417 scopus 로고    scopus 로고
    • Synthetic biology: Engineering Escherichia coli to see light
    • Levskaya, A. et al. Synthetic biology: engineering Escherichia coli to see light. Nature 438, 441-442 (2005).
    • (2005) Nature , vol.438 , pp. 441-442
    • Levskaya, A.1
  • 81
    • 2642555548 scopus 로고    scopus 로고
    • An autonomous molecular computer for logical control of gene expression
    • Benenson, Y., Gil, B., Ben-Dor, U., Adar, R. & Shapiro, E. An autonomous molecular computer for logical control of gene expression. Nature 429, 423-429 (2004).
    • (2004) Nature , vol.429 , pp. 423-429
    • Benenson, Y.1    Gil, B.2    Ben-Dor, U.3    Adar, R.4    Shapiro, E.5
  • 82
    • 0042360338 scopus 로고    scopus 로고
    • A deoxyribozyme-based molecular automaton
    • Stojanovic, M.N. & Stefanovic, D. A deoxyribozyme-based molecular automaton. Nat. Biotechnol. 21, 1069-1074 (2003).
    • (2003) Nat. Biotechnol. , vol.21 , pp. 1069-1074
    • Stojanovic, M.N.1    Stefanovic, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.