Germline hMSH2 promoter mutation in a Chinese HNPCC kindred: Evidence for dual role of LOH

Clinical Genetics

Volumn 72, Issue 6, 2007, Pages 556-561

  Yan, H ^a   Jin, H ^b   Xue, G ^a   Mei, Q ^a   Ding, F ^a   Hao, L ^c   Sun, Shu Han ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Nanjing Municipal Hospital of Traditional Chinese Medicine   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Hereditary non polyposis colorectal cancer; Loss of heterozygosity; Microsatellite instability; Mismatch repair gene; Promoter

Indexed keywords

ALANINE; E1A PROTEIN; GLYCINE; PROTEIN MLH1; PROTEIN MSH2; PROTEIN MSH6;

ADULT; AGED; AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; CANCER GENETICS; CHINESE; CLINICAL ARTICLE; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE COURSE; FAMILY; FEMALE; GENE ACTIVITY; GENE DELETION; GENE EXPRESSION; GENE MUTATION; GENETIC SCREENING; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MICROSATELLITE INSTABILITY; MUTANT; PRIORITY JOURNAL; PROMOTER REGION; SOMATIC MUTATION; WILD TYPE;

ASIAN CONTINENTAL ANCESTRY GROUP; BASE SEQUENCE; CHINA; COHORT STUDIES; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GERM-LINE MUTATION; HELA CELLS; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MICROSATELLITE INSTABILITY; MOLECULAR SEQUENCE DATA; MUTS HOMOLOG 2 PROTEIN; PEDIGREE; PROMOTER REGIONS (GENETICS);

EID: 36248980428     PISSN: 00099163     EISSN: 13990004     Source Type: Journal    
DOI: 10.1111/j.1399-0004.2007.00911.x     Document Type: Article

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