Antirhino/enteroviral vinylacetylene benzimidazoles: A study of their activity and oral plasma levels in mice

Journal of Medicinal Chemistry

Volumn 40, Issue 24, 1997, Pages 3937-3946

  Tebbe, Mark J ^a   Spitzer, Wayne A ^a   Victor, Frantz ^a   Miller, Shawn C ^a   Lee, Chris C ^a   Sattelberg Sr , Thomas R ^a   McKinney, Emma ^a   Tang, Joseph C ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(1 METHYLETHYL)SULFONYL] 6 [1 (3 FLUORO 4 METHOXYPHENYL) 1 BUTEN 3 YNYL] 1H BENZIMIDAZOL 2 AMINE; 1 [(1 METHYLETHYL)SULFONYL] 6 [1 (3 FLUOROPHENYL) 1 BUTEN 3 YNYL] 1H BENZIMIDAZOL 2 AMINE; 1 [(1 METHYLETHYL)SULFONYL] 6 [1 (3,5 DIFLUOROPHENYL) 1 BUTEN 3 YNYL] 1H BENZIMIDAZOL 2 AMINE; ANTIVIRUS AGENT; BENZIMIDAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; ENTEROVIRUS; HUMAN RHINOVIRUS; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; RHESUS MONKEY; STRUCTURE ACTIVITY RELATION;

ADMINISTRATION, ORAL; ANIMALS; ANTIVIRAL AGENTS; BENZIMIDAZOLES; BIOLOGICAL AVAILABILITY; ENTEROVIRUS; HELA CELLS; HUMANS; MICE; MICE, INBRED ICR; MICROBIAL SENSITIVITY TESTS; RHINOVIRUS; STRUCTURE-ACTIVITY RELATIONSHIP; VINYL COMPOUNDS;

EID: 0030859753     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970423k     Document Type: Article

References (31)

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