Synthesis, antiviral activity, and biological properties of vinylacetylene analogs of enviroxime

Journal of Medicinal Chemistry

Volumn 40, Issue 10, 1997, Pages 1511-1518

  Victor, Frantz ^a   Brown, Thomas J ^a   Campanale, Kristina ^a   Heinz, Beverly A ^a   Shipley, Lisa A ^a   Su, Kenneth S ^a   Tang, Joseph ^a   Vance, Lori M ^a   Spitzer, Wayne A ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [(1 METHYLETHYL)SULFONYL] 6 [1 (4 FLUOROPHENYL) 1 BUTEN 3 YNYL] 1H BENZIMIDAZOL 2 AMINE; ACETYLENE DERIVATIVE; BENZIMIDAZOLE DERIVATIVE; DRUG ANALOG; ENVIROXIME; ENVIROXIME DERIVATIVE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS A; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFICACY; DRUG METABOLISM; DRUG POTENCY; DRUG SENSITIZATION; DRUG SYNTHESIS; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; LIVER MICROSOME; MALE; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; RAT; REVERSED PHASE LIQUID CHROMATOGRAPHY; RHESUS MONKEY; VIRUS INFECTION;

EID: 0030920759     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm960718i     Document Type: Article

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