Duration-dependent cytoprotective versus inflammatory effects of lung epithelial fibroblast growth factor-7 expression

Experimental Lung Research

Volumn 33, Issue 8-9, 2007, Pages 385-417

  Tichelaar, Jay W ^a   Wesselkamper, Scott C ^a   Chowdhury, Supurna ^a   Yin, Hulian ^a   Berclaz, Pierre Yves ^b   Sartor, Maureen A ^a   Leikauf, George D ^a,c   Whitsett, Jeffrey A ^b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

ALI; Keratinocyte growth factor (KGF); Lung epithelium

Indexed keywords

KERATINOCYTE GROWTH FACTOR; MITOGENIC AGENT;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; GENE EXPRESSION PROFILING; INFLAMMATION; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROBLAST; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RNA ANALYSIS; SURVIVAL;

ANIMALS; CYTOPROTECTION; EPITHELIAL CELLS; FIBROBLAST GROWTH FACTOR 7; GENE EXPRESSION PROFILING; INFLAMMATION; LUNG; MICE; MICE, TRANSGENIC; NICKEL; PROTEINS; RESPIRATORY DISTRESS SYNDROME, ADULT; RNA, MESSENGER; TIME FACTORS;

EID: 36248930984     PISSN: 01902148     EISSN: 15210499     Source Type: Journal    
DOI: 10.1080/01902140701703226     Document Type: Article

References (67)

1. Michelson PH, Tigue M, Panos RJ, Sporn PH: Keratinocyte growth factor stimulates bronchial epithelial cell proliferation in vitro and in vivo. Am J Physiol. 1999;277:L737-L742.
2. Panos RJ, Rubin JS, Csaky KG, Aaronson SA, Mason RJ: Keratinocyte growth factor and hepatocyte growth factor/scatter factor are heparin-binding growth factors for alveolar type II cells in fibroblast-conditioned medium. J Clin Invest, 1993;92:969-77.
3. Ulich TR, Yi ES, Longmuir K, Yin S, Biltz R, Morris CF, Housley RM, Pierce GF: Keratinocyte growth factor is a growth factor for type II pneumocytes in vivo. J Clin Invest. 1994;93:1298-306.
4. Ikegami M, Jobe AH, Havill AM: Keratinocyte growth factor increases surfactant pool sizes in premature rabbits. Am J Respir Crit Care Med. 1997;155:1155-1158.
5. Sugahara K, Rubin JS, Mason RJ, Aronsen EL, Shannon JM: Keratinocyte growth factor increases mRNAs for SP-A and SP-B in adult rat alveolar type II cells in culture. Am J Physiol. 1995;269:L344-L350.
6. Borok Z, Danto SI, Dimen LL, Zhang XL, Lubman RL: Na(+)-K(+)-ATPase expression in alveolar epithelial cells: upregulation of active ion transport by KGF. Am J Physiol. 1998;274:L149-L158.
7. Adamson IY, Bakowska J: Relationship of keratinocyte growth factor and hepatocyte growth factor levels in rat lung lavage fluid to epithelial cell regeneration after bleomycin. Am J Pathol. 1999;155:949-954.
8. Charafeddine L, D'Angio CT, Richards JL, Stripp BR, Finkelstein JN, Orlowski CC, LoMonaco MB, Paxhia A, Ryan RM: Hyperoxia increases keratinocyte growth factor mRNA expression in neonatal rabbit lung. Am J Physiol. 1999;276:L105-L113.
9. Stern JB, Fierobe L, Paugam C, Rolland C, Dehoux M, Petiet A, Dombret MC, Mantz J, Aubier M, Crestani B: Keratinocyte growth factor and hepatocyte growth factor in bronchoalveolar lavage fluid in acute respiratory distress syndrome patients. Crit Care Med. 2000;28:2326-2333.
10. Verghese GM, McCormick-Shannon K, Mason RJ, Matthay MA: Hepatocyte growth factor and keratinocyte growth factor in the pulmonary edema fluid of patients with acute lung injury. Biologic and clinical significance. Am J Respir Crit Care Med. 1998;158:386-394.
11. Waters CM, Savla U, Panos RJ: KGF prevents hydrogen peroxide-induced increases in airway epithelial cell permeability. Am J Physiol. 1997;272:L681-L689.
12. Yano T, Deterding RR, Simonet WS, Shannon JM, Mason RJ: Keratinocyte growth factor reduces lung damage due to acid instillation in rats. Am J Respir Cell Mol Biol. 1996;15:433-442.
13. Deterding RR, Havill AM, Yano T, Middleton SC, Jacoby CR, Shannon JM, Simonet WS, Mason RJ: Prevention of bleomycin-induced lung injury in rats by keratinocyte growth factor. Proc Assoc Am Physicians. 1997;109:254-268.
14. Panos RJ, Bak PM, Simonet WS, Rubin JS, Smith LJ: Intratracheal instillation of keratinocyte growth factor decreases hyperoxia-induced mortality in rats. J Clin Invest. 1995;96:2026-2033.
15. Guery BP, Mason CM, Dobard EP, Beaucaire G, Summer WR, Nelson S: Keratinocyte growth factor increases transalveolar sodium reabsorption in normal and injured rat lungs. Am J Respir Crit Care Med. 1997;155:1777-1784.
16. Viget NB, Guery BP, Ader F, Neviere R, Alfandari S, Creuzy C, Roussel-Delvallez M, Foucher C, Mason CM, Beaucaire G, Pittet JF: Keratinocyte growth factor protects against Pseudomonas aeruginosa-induced lung injury. Am J Physiol Lung Cell Mol Physiol. 2000;279:L1199-L1209.
17. Haddad IY, Panoskaltsis-Mortari A, Ingbar DH, Resnik ER, Yang S, Farrell CL, Lacey DL, Cornfield DN, Blazar BR: Interactions of keratinocyte growth factor with a nitrating species after marrow transplantation in mice. Am J Physiol. 1999;277:L391-L400.
18. Tichelaar JW, Lu W, Whitsett JA: Conditional expression of fibroblast growth factor-7 in the developing and mature lung. J Biol Chem. 2000;275:11858-11864.
19. Wesselkamper SC, McDowell SA, Medvedovic M, Dalton TP, Deshmukh HS, Sartor MA, Case LM, Henning LN, Borchers MT, Tomlinson CR, Prows DR, Leikauf GD: The role of metallothionein in the pathogenesis of acute lung injury. Am J Respir Cell Mol Biol. 2006;34:73-82.
20. Shibata Y, Zsengeller Z, Otake K, Palaniyar N, Trapnell BC: Alveolar macrophage deficiency in osteopetrotic mice deficient in macrophage colony-stimulating factor is spontaneously corrected with age and associated with matrix metalloproteinase expression and emphysema. Blood. 2001;98:2845-2852.
21. Wesselkamper SC, Prows DR, Biswas P, Willeke K, Bingham E, Leikauf GD: Genetic susceptibility to irritant-induced acute lung injury in mice. Am J Physiol Lung Cell Mol Physiol. 2000;279:L575-L582.
22. Noah TL, Murphy PC, Alink JJ, Leigh MW, Hull WM, Stahlman MT, Whitsett JA: Bronchoalveolar lavage fluid surfactant protein-A and surfactant protein-D are inversely related to inflammation in early cystic fibrosis. Am J Respir Crit Care Med. 2003;168:685-691.
23. Berclaz PY, Shibata Y, Whitsett JA, Trapnell BC: GM-CSF, via PU.1, regulates alveolar macrophage Fcgamma R-mediated phagocytosis and the IL-18/IFN-gamma -mediated molecular connection between innate and adaptive immunity in the lung. Blood. 2002;100:4193-4200.
24. Guo J, Sartor M, Karyala S, Medvedovic M, Kann S, Puga A, Ryan P, Tomlinson CR: Expression of genes in the TGF-beta signaling pathway is significantly deregulated in smooth muscle cells from aorta of aryl hydrocarbon receptor knockout mice. Toxicol Appl Pharmacol. 2004;194:79-89.
25. Karyala S, Guo J, Sartor M, Medvedovic M, Kann S, Puga A, Ryan P, Tomlinson CR: Different global gene expression profiles in benzo[a]pyrene- and dioxin-treated vascular smooth muscle cells of AHR-knockout and wild-type mice. Cardiovasc Toxicol. 2004;4:47-73.
26. Sartor M, Schwanekamp J, Halbleib D, Mohamed I, Karyala S, Medvedovic M, Tomlinson CR: Microarray results improve significantly as hybridization approaches equilibrium. Biotechniques. 2004;36:790-796.
27. Sartor MA, Tomlinson CR, Wesselkamper SC, Sivaganesan S, Leikauf GD, Medvedovic M: Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments. BMC Bioinformatics. 2006;7:538.
28. Smyth KG: Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol. 2004;3.
29. Dennis G Jr, Sherman BT, Hosack DA, Yang J, Gao W, Lane HC, Lempicki RA:DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 2003;4:P3.
30. Benjamini Y, Hochberg Y: Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B. 1995;57:289-300.
31. Xu X, McCormick-Shannon K, Voelker DR, Mason RJ: KGF increases SP-A and SP-D mRNA levels and secretion in cultured rat alveolar type II cells. Am J Respir Cell Mol Biol. 1998;18:168-178.
32. Ueno T, Linder S, Na CL, Rice WR, Johansson J, Weaver TE: Processing of pulmonary surfactant protein B by napsin and cathepsin H. J Biol Chem. 2004;279:16178-16184.
33. Hardie WD, Prows DR, Piljan-Gentle A, Dunlavy MR, Wesselkamper SC, Leikauf GD, Korfhagen TR: Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha. Am J Respir Cell Mol Biol. 2002;26:430-437.
34. Atabai K, Ishigaki M, Geiser T, Ueki I, Matthay MA, Ware LB: Keratinocyte growth factor can enhance alveolar epithelial repair by nonmitogenic mechanisms. Am J Physiol Lung Cell Mol Physiol. 2002;283:L163-L169.
35. Shenkar R, Abraham E: Mechanisms of lung neutrophil activation after hemorrhage or endotoxemia: roles of reactive oxygen intermediates, NF-kappa B, and cyclic AMP response element binding protein. J Immunol. 1999;163:954-962.
36. Zhao Q, Simpson LG, Driscoll KE, Leikauf GD: Chemokine regulation of ozone-induced neutrophil and monocyte inflammation. Am J Physiol. 1998;274:L39-L46.
37. Nishina K, Zhang F, Nielsen LD, Edeen K, Wang J, Mason RJ: Expression of CINC-2beta is related to the state of differentiation of alveolar epithelial cells. Am J Respir Cell Mol Biol. 2005;33:505-512.
38. Clark JC, Tichelaar JW, Wert SE, Itoh N, Perl AK, Stahlman MT, Whitsett JA: FGF-10 disrupts lung morphogenesis and causes pulmonary adenomas in vivo. Am J Physiol Lung Cell Mol Physiol. 2001;280:L705-L715.
39. Zhao B, Chua SS, Burcin MM, Reynolds SD, Stripp BR, Edwards RA, Finegold MJ, Tsai SY, DeMayo FJ: Phenotypic consequences of lung-specific inducible expression of FGF-3. Proc Natl Acad Sci USA. 2001;98:5898-5903.
40. Fisher GH, Wellen SL, Klimstra D, Lenczowski JM, Tichelaar JW, Lizak MJ, Whitsett JA, Koretsky A, Varmus HE: Induction and apoptotic regression of lung adenocarcinomas by regulation of a K-Ras transgene in the presence and absence of tumor suppressor genes. Genes Dev. 2001;15:3249-3262.
41. Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM: High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras. Cancer Res. 2006;66:4198-4207.
42. Ballaz S, Mulshine JL: The potential contributions of chronic inflammation to lung carcinogenesis. Clin Lung Cancer. 2003;5:46-62.
43. Hayashi M, Hayashi Y, Liu CY, Tichelaar JW, Kao WW: Over expression of FGF7 enhances cell proliferation but fails to cause pathology in corneal epithelium of Kerapr-rtTA/FGF7 bitransgenic mice. Mol Vis. 2005;11:201-207.
44. Wang Y, Folkesson H, Jayr C, Ware L, Matthay M: Alveolar epithelial fluid transport can be simultaneously upregulated by both KGF and beta-agonist therapy. J Appl Physiol. 1999;87:1852-1860.
45. Borok Z, Mihyu S, Fernandes VF, Zhang XL, Kim KJ, Lubman RL: KGF prevents hyperoxia-induced reduction of active ion transport in alveolar epithelial cells. Am J Physiol. 1999;276:C1352-C1360.
46. Adamson IY, Bakowska J: KGF and HGF are growth factors for mesothelial cells in pleural lavage fluid after intratracheal asbestos. Exp Lung Res. 2001;27:605-616.
47. Danan C, Franco ML, Jarreau PH, Dassieu G, Chailley-Heu B, Bourbon J, Delacourt C: High concentrations of keratinocyte growth factor in airways of premature infants predicted absence of bronchopulmonary dysplasia. Am J Respir Crit Care Med. 2002;165:1384-1387.
48. Yano T, Mason RJ, Pan T, Deterding RR, Nielsen LD, Shannon JM: KGF regulates pulmonary epithelial proliferation and surfactant protein gene expression in adult rat lung. Am J Physiol Lung Cell Mol Physiol. 2000;279:L1146-L1158.
49. Crouch E, Wright JR: Surfactant proteins a and d and pulmonary host defense. Annu Rev Physiol. 2001;63:521-554.
50. LeVine AM, Whitsett JA: Pulmonary collectins and innate host defense of the lung. Microbes Infect. 2001;3:161-166.
51. Ryan MA, Akinbi HT, Serrano AG, Perez-Gil J, Wu H, McCormack FX, Weaver TE: Antimicrobial activity of native and synthetic surfactant protein B peptides. J Immunol. 2006;176:416-425.
52. Ikegami M, Whitsett JA, Martis PC, Weaver TE: Reversibility of lung inflammation caused by SP-B deficiency. Am J Physiol Lung Cell Mol Physiol. 2005;289:L962-L970.
53. Melton KR, Nesslein LL, Ikegami M, Tichelaar JW, Clark JC, Whitsett JA, Weaver TE: SP-B deficiency causes respiratory failure in adult mice. Am J Physiol Lung Cell Mol Physiol. 2003;285:L543-L549.
54. Wesselkamper SC, Case LM, Henning LN, Borchers MT, Tichelaar JW, Mason JM, Dragin N, Medvedovic M, Sartor MA, Tomlinson CR, Leikauf GD: Gene expression changes during the development of acute lung injury: role of transforming growth factor beta. Am J Respir Crit Care Med. 2005;172:1399-1411.
55. Haddad IY, Milla C, Yang S, Panoskaltsis-Mortari A, Hawgood S, Lacey DL, Blazar BR: Surfactant protein a is a required mediator of keratinocyte growth factor after experimental marrow transplantation. Am J Physiol Lung Cell Mol Physiol. 2003;285:L602-L610.
56. Chapman KE, Waters CM, Miller WM: Continuous exposure of airway epithelial cells to hydrogen peroxide: protection by KGF. J Cell Physiol. 2002;192:71-80.
57. Boardman KC, Aryal AM, Miller WM, Waters CM: Actin re-distribution in response to hydrogen peroxide in airway epithelial cells. J Cell Physiol. 2004;199:57-66.
58. Turksen K, Troy TC: Barriers built on claudins. J Cell Sci. 2004;117:2435-2447.
59. Wang F, Daugherty B, Keise LL, Wei Z, Foley JP, Savani RC, Koval M: Heterogeneity of claudin expression by alveolar epithelial cells. Am J Respir Cell Mol Biol. 2003;29:62-70.
60. Coyne CB, Gambling TM, Boucher RC, Carson JL, Johnson LG: Role of claudin interactions in airway tight junctional permeability. Am J Physiol Lung Cell Mol Physiol. 2003;285:L1166-L1178.
61. Turksen K, Troy TC: Permeability barrier dysfunction in transgenic mice overexpressing claudin 6. Development. 2002;129:1775-1784.
62. Devireddy LR, Gazin C, Zhu X, Green MR: A cell-surface receptor for lipocalin 24p3 selectively mediates apoptosis and iron uptake. Cell. 2005;123:1293-1305.
63. Mori K, Lee HT, Rapoport D, Drexler IR, Foster K, Yang J, Schmidt-Ott KM, Chen X, Li JY, Weiss S, Mishra J, Cheema FH, Markowitz G, Suganami T, Sawai K, Mukoyama M, Kunis C, D'Agati V, Devarajan P, Barasch J: Endocytic delivery of lipocalin-siderophore-iron complex rescues the kidney from ischemia-reperfusion injury. J Clin Invest. 2005;115:610-621.
64. Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR: Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. Am J Respir Crit Care Med. 2002;166:1498-1509.
65. Krop I, Parker MT, Bloushtain-Qimron N, Porter D, Gelman R, Sasaki H, Maurer M, Terry MB, Parsons R, Polyak K: HIN-1, an inhibitor of cell growth, invasion, and AKT activation. Cancer Res. 2005;65:9659-9669.
66. Triantafilou M, Brandenburg K, Gutsmann T, Seydel U, Triantafilou K: Innate recognition of bacteria: engagement of multiple receptors. Crit Rev Immunol. 2002;22:251-268.
67. Bingle CD, Craven CJ: Meet the relatives: a family of BPI- and LBP-related proteins. Trends Immunol. 2004;25:53-55.