Restriction endonuclease-mediated selective polymerase chain reaction: A novel assay for the detection of K-ras mutations in clinical samples

American Journal of Pathology

Volumn 153, Issue 2, 1998, Pages 373-379

  Ward, Robyn ^a   Hawkins, Nicholas ^b   O'Grady, Roslynn ^a   Sheehan, Catherine ^a   O'Connor, Terence ^a   Impey, Helen ^c   Roberts, Natalie ^c   Fuery, Caroline ^c   Todd, Alison ^c  

^a ST VINCENT S HOSPITAL   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RESTRICTION ENDONUCLEASE;

ARTICLE; CLINICAL TRIAL; COLORECTAL CARCINOMA; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC VALUE; DNA DETERMINATION; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; ONCOGENE K RAS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TECHNIQUE;

EID: 0031877635     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)65581-2     Document Type: Article

References (30)

1. Barbacid M: ras genes. Annu Rev Biochem 1987, 56:779-827
2. Almoguera C, Shibata D, Forrester K, Martin J, Arnheim N, Perucho M: Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes. Cell 1988, 53:549-554
3. Bos JL: ras oncogenes in human cancer: a review. Cancer Res 1989, 49:4682-4689
4. Vogelstein B, Fearon ER, Hamilton SR, Kern SE, Preisinger AC, Leppert M, Nakamura Y, White R, Smits AMM, Bos JI: Genetic alterations during colorectal-tumor development. N Engl J Med 1988, 319:525-532
5. Sidransky D, Tokino Y, Hamilton SR, Kinzler KW, Levin B, Frost P, Vogelstein B: Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 1992, 256:102-105
6. Losi L, Benhattar J, Costa J: Stability of K-ras mutations throughout the natural history of human colorectal cancer. Eur J Cancer 1992, 28A:1115-1120
7. Ratio C, Flamini G, Sofo L, Nucera P, Ippoliti M, Curigliano G, Ferretti G, Sgambato A, Merico M, Doglietto GB, Cittadini A, Crucitti F: Detection of oncogene mutation from neoplastic colonic cells exfoliated in feces. Dis Colon Rectum 1996, 39:1238-1244
8. Hayashi N, Ito I, Yanagisawa A, Kato Y, Nakamori S, Imaoka S, Watanabe H, Ogawa M, Nakamura Y: Genetic diagnosis of lymphnode metastasis in colorectal cancer. Lancet 1995, 345:1257-1259
9. Hardingham JE, Kotasek D, Sage RE, Eaton MC, Pascoe VH, Dobrovic A: Detection of circulating tumor cells in colorectal cancer by immunobead-PCR is a sensitive prognostic marker for relapse of disease. Mol Med 1995, 1:789-794
10. Cohen JB, Levinson AD: A point mutation in the last intron responsible for increased expression and transforming activity of the c-Ha-ras oncogene. Nature 1988, 334:119-124
11. Todd AV, Hand HJ: Allele-specific enrichment: a method for the detection of low level N-ras gene mutations in acute myeloid leukemia. Leukemia 1991, 5:160-161
12. Levi S, Urbano-Ispizua A, Gill R, Thomas DM, Gilbertson J, Foster C, Marshall CJ: Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique. Cancer Res 1991, 51:3497-3502
13. Singh J, Rao CV, Kulkarni N, Simi B, Reddy BS: Molecular markers as intermediate end-points in chemoprevention of colon cancer: modulation of ras activation by sulindac and phenylhexylisothiocyanate during colon carcinogenesis. Int J Oncol 1994, 5:1009-1018
14. Dukes CE, Bussey HJR: The spread of rectal cancer and its effect on prognosis. Br J Cancer 1958, 12:309-320
15. Lineweaver W: Staging of colon cancer. Contemp Surg 1984, 25:19
16. Hamazaki S, Koshiba M, Habuchi T, Takahashi R, Sugiyama T: The effect of formalin fixation on restriction endonuclease digestion of DNA and PCR amplification. Pathol Res Pract 1993, 189:553-557
17. Ward RL, Santiago F, Hawkins NJ, Coomber D, Oconnor T, Todd AV: A rapid PCR ELISA for the detection of activated K-ras in colorectal cancer. J Clin Pathol 1995, 48:M273-M277
18. Hasegawa H, Ueda M, Watanabe M, Teramoto T, Mukai M, Kitajima M: K-ras gene mutations in early colorectal cancer: flat elevated vs. polyp-forming cancer. Oncogene 1995, 10:1413-1416
19. Minamoto T, Ronai Z, Yamashita N, Ochiai A, Sugimura T, Mai M, Esumi H: Detection of Ki-ras mutation in non-neoplastic mucosa of Japanese patients with colorectal cancers. Int J Oncol 1994, 4:397-401
20. Sasaki H, Nishii H, Takahashi H, Tada A, Furusato M, Terashima Y, Siegal GP, Parker SL, Kohler MF Berchuck A: Mutation of the Ki-ras protooncogene in human endometrial hyperplasia and carcinoma Cancer Res 1993, 53:1906-1910
21. Scarpa A, Capeili P, Villanueva A, Zamboni G, Lluìs F, Accolla R, Mariuzzi G, Capella G: Pancreatic cancer in Europe: Ki-ras gene mutation pattern shows geographical differences. Int J Cancer 1994, 57:167-171
22. Fung C, Bragg T, Newland R, Dent O, Nicholson G, Bokey L, Chapuis P: K-ras mutation, and loss of heterozygosity of chromosome 17p, and survival in colorectal cancer. Aust NZ J Surg 1997, 67:239-244
23. Thomas RJS, Liu YS, St Clair F, Norris PM, Valentine R, Phillips WA: Frequency and clinico-pathological associations of ras mutations in colorectal cancer in the Victorian population. Aust NZ J Surg 1997, 67:233-238
24. Greer CE, Wheeler CM, Manos MM: Sample preparation and PCR amplification from paraffin-embedded tissues. PCR Methods Appl 1994, 3:S113-S122
25. Alaibac M, Filotico R, Giannella C, Paradiso A, Labriola A, Marzullo F: The effect of fixation type on DNA extracted from paraffin-embedded tissue for PCR studies in dermatopathology. Dermatology 1997, 195: 105-107
26. Merkelbach S, Gehlen J, Handt S, Fuzesi L: Novel enzyme immunoassay and optimized DNA extraction for the detection of polymerase chain reaction-amplified viral DNA from paraffin-embedded tissue. Am J Pathol 1997, 150:1537-1546
27. Koffa M, Malamou-Mitsi V, Agnantis NJ, Spandidos DA: Mutational activation of K-ras oncogene in human breast tumors. Int J Oncol 1994, 4:573-576
28. Nagata Y, Abe M, Kobayashi K, Saiki S, Kotake T, Yoshikawa K, Ueda R, Nakayama E, Shiku H: Point mutations of c-ras genes in human bladder cancer and kidney cancer. Jpn J Cancer Res 1990, 81:22-27
29. Shibata D, Martin WJ, Arnheim N: Analysis of DNA sequences in forty-year-old paraffin-embedded thin-tissue sections: a bridge between molecular biology and classical histology. Cancer Res 1988, 48:4564-4566
30. Goelz SE, Hamilton SR, Vogelstein B: Purification of DNA from formaldehyde fixed and paraffin embedded human tissue. Biochem Biophys Res Commun 1985, 130:118-126