Engineered minichromosomes in plants

Current Opinion in Biotechnology

Volumn 18, Issue 5, 2007, Pages 425-431

  Yu, Weichang ^a   Han, Fangpu ^a   Birchler, James A ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLONING; GENE EXPRESSION; HERBICIDES; PLANTS (BOTANY);

CROP QUALITY; HERBICIDE TOLERANCE; MINICHROMOSOMES; TRANSGENES;

CHROMOSOMES;

ARTIFICIAL CHROMOSOME; BIOENGINEERING; BIOTECHNOLOGY; CENTROMERE; EPIGENETICS; GENE EXPRESSION; GENE SEQUENCE; GENE TECHNOLOGY; GENETIC ENGINEERING; GENETIC RECOMBINATION; MINICHROMOSOME; NONHUMAN; PLANT CHROMOSOME; PRIORITY JOURNAL; REVIEW; TRANSGENE;

CHROMOSOMES, PLANT; GENETIC ENGINEERING; PLANT PROTEINS; PLANTS, GENETICALLY MODIFIED; RECOMBINANT PROTEINS;

BACTERIA (MICROORGANISMS); HEXAPODA;

EID: 36148965481     PISSN: 09581669     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.copbio.2007.09.005     Document Type: Review

References (31)

1. Halpin C. Gene stacking in transgenic plants - the challenge for 21st century plant biotechnology. Plant Biotechnol J 3 (2005) 141-155. A review on gene stacking in plant biotechnology noting the difficulty in advancing current technology of 'input trait' to the second-generation 'output trait' GM crops.
2. Gleba Y., Klimyuk V., and Marillonnet S. Viral vectors for the expression of proteins in plants. Curr Opin Biotechnol 18 (2007) 134-141
3. Bock R. Plastid biotechnology: prospects for herbicide and insect resistance, metabolic engineering and molecular farming. Curr Opin Biotechnol 18 (2007) 100-106
4. Maliga P. Plastid transformation in higher plants. Annu Rev Plant Biol 55 (2004) 289-313
5. Mayfield S.P., Manuell A.L., Chen S., Wu J., Tran M., Siefker D., Muto M., and Marin-Navarro J. Chlamydomonas reinhardtii chloroplasts as protein factories. Curr Opin Biotechnol 18 (2007) 126-133
6. Yu W., Han F., Gao Z., Vega J.M., and Birchler J.A. Construction and behavior of engineered minichromosomes in maize. Proc Natl Acad Sci U S A 104 (2007) 8924-8929. This paper describes the targeting of minichromosomes with genes for applications in plant genetic engineering. It provides proof of concept that engineered minichromosomes can be used as platforms for the second-generation technology of 'output trait' GM crops. Also demonstrated that maize supernumerary B chromosomes can support foreign gene expression and can be modified as vectors for genetic engineering.
7. Basu J., and Willard H.F. Artificial and engineered chromosomes: non-integrating vectors for gene therapy. Trends Mol Med 11 (2005) 251-258. Review of current mammalian minichromosome technology and applications in gene therapy.
8. Brock R.D., and Pryor A.J. An unstable minichromosome generates variegated oil yellow maize seedlings. Chromosoma 104 (1996) 575-584
9. McClintock B. A correlation of ring-shaped chromosomes with variegation in Zea mays. Proc Natl Acad Sci U S A 18 (1932) 677-681
10. Han F., Lamb J.C., and Birchler J.A. High frequency of centromere inactivation resulting in stable dicentric chromosomes of maize. Proc Natl Acad Sci U S A 103 (2006) 3238-3243. This paper provides a protocol for the generation of minichromosomes by the BFB cycle. Either normal minichromosomes or dicentric minichromosomes, which are the result of centromere inactivation, are produced.
11. Kato A., Zheng Y.Z., Auger D.L., Phelps-Durr T., Bauer M.J., Lamb J.C., and Birchler J.A. Minichromosomes derived from the B chromosome of maize. Cytogenet Genome Res 109 (2005) 156-165
12. Zheng Y.Z., Roseman R.R., and Carlson W.R. Time course study of the chromosome-type breakage-fusion-bridge cycle in maize. Genetics 153 (1999) 1435-1444
13. Yu W., Lamb J.C., Han F., and Birchler J.A. Telomere-mediated chromosomal truncation in maize. Proc Natl Acad Sci U S A 103 (2006) 17331-17336. This paper demonstrated that telomere arrays from Arabidopsis can make chromosome fragmentation at the site of telomere sequence integration. This technology has been subsequently used for the creation of engineered minichromosomes for plant genetic engineering.
14. Jones N.R., and Rees H. B Chromosomes (1982), Academic Press, London
15. Harrington J.J., Van Bokkelen G., Mays R.W., Gustashaw K., and Willard H.F. Formation of de novo centromeres and construction of first-generation human artificial microchromosomes. Nat Genet 15 (1997) 345-355
16. Murray W.M., and Szostack J.W. Construction of artificial chromosomes in yeast. Nature 305 (1983) 189-193
17. Hudakova S., Michalek W., Presting G.G., ten Hoopen R., dos Santos K., Jasencakova Z., and Schubert I. Sequence organization of barley centromeres. Nucleic Acids Res 29 (2001) 5029-5035
18. Jiang J., Nasuda S., Dong F., Scherrer C.W., Woo S.S., Wing R.A., Gill B.S., and Ward D.C. A conserved repetitive DNA element located in the centromeres of cereal chromosomes. Proc Natl Acad Sci U S A 93 (1996) 14210-14213
19. Luo S., Hall A.E., Hall S.E., and Preuss D. Whole-genome fractionation rapidly purifies DNA from centromeric regions. Nat Methods 1 (2004) 67-71
20. Page B.T., Wanous M.K., and Birchler J.A. Characterization of a maize chromosome 4 centromeric sequence: evidence for an evolutionary relationship with the B chromosome centromere. Genetics 159 (2001) 291-302
21. Phan B.H., Jin W., Topp C.N., Zhong C.X., Jiang J., Dawe R.K., and Parrott W.A. Transformation of rice with long DNA-segments consisting of random genomic DNA or centromere-specific DNA. Transgenic Res 16 (2007) 341-351. In this paper, cloned centromere sequences from maize were transformed into maize and rice. The introduced sequences integrated into chromosomes without centromere function.
22. Ow D.W. GM maize from site-specific recombination technology, what next?. Curr Opin Biotechnol 18 (2007) 115-120. This paper outlines strategies to use site-specific recombination system in future GM crops.
23. Wright D.A., Townsend J.A., Winfrey Jr. R.J., Irwin P.A., Rajagopal J., Lonosky P.M., Hall B.D., Jondle M.D., and Voytas D.F. High-frequency homologous recombination in plants mediated by zinc-finger nucleases. Plant J 44 (2005) 693-705. This paper describes the application of a homologous recombination system to plants.
24. Yu W, Birchler JA: Minichromosomes: the next generation technology for genetic engineering. ISB News Report 2007.
25. Hamilton C.M., Frary A., Lewis C., and Tanksley S.D. Stable transfer of intact high molecular weight DNA into plant chromosomes. Proc Natl Acad Sci U S A 93 (1996) 9975-9979
26. Liu Y.G., Shirano Y., Fukaki H., Yanai Y., Tasaka M., Tabata S., and Shibata D. Complementation of plant mutants with large genomic DNA fragments by a transformation-competent artificial chromosome vector accelerates positional cloning. Proc Natl Acad Sci U S A 96 (1999) 6535-6540
27. Greber D., and Fussenegger M. Multi-gene engineering: simultaneous expression and knockdown of six genes off a single platform. Biotechnol Bioeng 96 (2007) 821-834. This paper provides a strategy for multigene expression. Six genes (three structural genes and three RNAi genes) were expressed from a polycistronic transcription unit.
28. Nagaki K., Cheng Z., Ouyang S., Talbert P.B., Kim M., Jones K.M., Henikoff S., Buell C.R., and Jiang J. Sequencing of a rice centromere uncovers active genes. Nat Genet 36 (2004) 138-145
29. Yan H., Jin W., Nagaki K., Tian S., Ouyang S., Buell C.R., Talbert P.B., Henikoff S., and Jiang J. Transcription and histone modifications in the recombination-free region spanning a rice centromere. Plant Cell 17 (2005) 3227-3238
30. Spence J.M., Mills W., Mann K., Huxley C., and Farr C.J. Increased missegregation and chromosome loss with decreasing chromosome size in vertebrate cells. Chromosoma 115 (2006) 60-74. In this paper were created tiny minichromosomes in chicken cells by telomere truncation. This paper demonstrated the instability of extremely small minichromosomes less than 550 kb.
31. Kaszas E., and Birchler J.A. Meiotic transmission rates correlate with physical features of rearranged centromeres in maize. Genetics 150 (1998) 1683-1692