Sex differences in skeletal development

Advances in Molecular and Cell Biology

Volumn 34, Issue , 2004, Pages 229-245

  Fitzpatrick, Lorraine A ^a  

^a NONE

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EID: 36148944297     PISSN: 15692558     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S1569-2558(03)34016-0     Document Type: Article

References (74)

1. J Arts G.G Kuiper J.M Janssen J.-A Gustafsson C.W Lowik H.A Pols J.P van Leeuwen Differential expression of estrogen receptors alpha and beta during differentiation of human osteoblast SV-HFO cells Endocrinology 138 1997 5067 5070
2. L.K Bachrach D.K Katzman I.F Litt D Guido R Marcus Recovery from osteopenia in adolescent girls with anorexia nervosa J. Clin. Endocrinol. Metab. 72 1991 602 606
3. D.A Bailey H.A McKay R.L Mirwald P.R.E Crocher R.A Faulkner A six-year longitudinal study of the relationship of physical activity to bone mineral accrual in growing children. The University of Saskatchewan Bone Mineral Accrual Study J. Bone. Miner. Res. 14 1999 1672 1679
4. J.P Bilezikian A Morishima J Bell M.M Grumbach Increased bone mass as a result of estrogen therapy in a man with aromatase deficiency N. Engl. J. Med. 339 1998 599 603
5. S Bord A Horner S Beavan J Compston Estrogen receptors alpha and beta are differentially expressed in developing human bone J. Clin. Endocrinol. Metab. 86 2001 2309 2314
6. N Bucay I Sarosi C.R Dunstan S Morony J Tarpley C Capparelli S Scully H.L Tan W Xu D.L Lacey W.J Boyle W.S Simonet Osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification Genes Dev. 12 1998 1260 1268
7. J.R Buchanan P Hospodar C Myers P Leuenberger L Demers Effect of excess androgens on bone density in young women J. Clin. Endocrinol. Metab. 67 1988 937 943
8. F Callies M Fassnacht J.C Van Vlijmen I Koehler D Huebler M.J Seibel W Arlt B Allolio Dehydroepiandrosterone replacement in women with adrenal insufficiency: effects on body composition, serum leptin, bone turnover, and exercise capacity J. Clin. Endocrinol. Metab. 86 2001 1968 1972
9. C Carani K Qin M Simoni M Faustini-Fustini S Serpente J Boyd K.S Korach E.R Simpson Effect of testosterone and estradiol in a man with aromatase deficiency N. Engl. J. Med. 337 1997 91 95
10. P Coen H Kulin T Ballantine R Zaino E Frauenhoffer D Boal S Inkster A Brodie R Santen An aromatase-producing sex-cord tumor resulting in prepubertal gynecomastia N. Engl. J. Med. 324 1991 317 322
11. D.S Colvard E.F Eriksen P.E Keeting E.M Wilson D.B Lubahn F.S French B.L Riggs T.C Spelsberg Identification of androgen receptors in normal human osteoblast-like cells Proc. Natl Acad. Sci. USA 86 1989 854 857
12. J.F Couse K.S Korach Estrogen receptor null mice: what have we learned and where will they lead us Endocr. Rev. 20 1999 358 417
13. S.R Davis P.I McCloud B.J.G Strauss H.G Burger Testosterone enhances estradiol's effects on postmenopausal bone density and sexuality Maturitas 21 1995 227 236
14. J Deladoey C Fluck M Bex N Yoshimura N Harada P.E Mullis Aromatase deficiency caused by a novel P450 arom gene mutation: impact of absent estrogen production on serum gonadotropin concentration in a boy J. Clin. Endocrinol. Metab. 84 1999 4050 4054
15. T Douchi T Oki H Yamasaki R Kuwahata M Nakae Y Nagata Relationship of androgens to muscle size and bone mineral density in women with polycystic ovary syndrome Obstet. Gynecol. 98 2001 445 449
16. P.R Ebeling Osteoporosis in men. New insights into aetiology, pathogenesis, prevention, and management Drugs Aging 13 1998 421 434
17. A Falahati-Nini B.L Riggs E.J Atkinson W.M O'Fallon R Eastell S Khosla Relative contributions of testosterone and estrogen in regulating bone resorption and formation in normal elderly men J. Clin. Invest. 106 2000 1553 1560
18. J.S Finkelstein A Klibanski R.M Neer S.L Greenspan D.I Rosenthal W.F Crowley Jr Osteoporosis in men with idiopathic hypogonadotropic hypogonadism Ann. Intern. Med. 106 1987 354 361
19. J.S Finkelstein R.M Neer B.M.K Biller J.D Crawford A Klibanski Osteopenia in men with a history of delayed puberty N. Engl. J. Med. 326 1992 600 604
20. C Gennari D Agnusdei S Gonnelli P Nardi Effects of nandrolone decanoate therapy on bone mass and calcium metabolism in women with established post-menopausal osteoporosis: a double-blind placebo-controlled study Maturitas 11 1989 187 197
21. M.A Gentile H Zhang S Harada Bone response to estrogen replacement in OVX double estrogen receptor- (alpha and beta) knockout mice J. Bone. Miner. Res. 16 2001 S146
22. 3 or intermittent calcim infusion therapy on bone mineral content, bone remodeling and fracture rate in symptomatic osteoporosis: a double-blind controlled study Bone Miner. 1 1986 347 357
23. V Gilsanz M.I Boechat R Gilsanz M.L Loro T.F Roe W.G Goodman Gender differences in vertebral sizes in adults: biomechanical implications Radiology 190 1995 678 682
24. V Gilsanz M.I Boechat T.F Roe M.L Loro J.W Sayre W.G Goodman Gender differences in vertebral body sizes in children and adolescents Radiology 190 1994 673 677 Abstract
25. V Gilsanz A Kovanlikaya G Costin T.F Roe J Sayre F Kaufman Differential effect of gender on the size of the bones in the axial and appendicular skeletons J. Clin. Endocrinol. Metab. 82 1997 1603 1607
26. C Good M Tulchinsky D Mauger L.M Demers R.S Legro Bone mineral density and body composition in lean women with polycystic ovary syndrome Fertil. Steril. 72 1999 21 25
27. G.A Greendale S Edelstein E Barrett-Connor Endogenous sex steroids and bone mineral density in older women and men: the Rancho Bernardo study J. Bone Miner. Res. 12 1997 1833 1843
28. M.M Grumbach R.J Auchus Estrogen: consequences and implications of human mutations in synthesis and action J. Clin. Endocrinol. Metab. 84 1999 4677 4694
29. L.C Hofbauer A.E Heufelder The role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in the pathogenesis and treatment of metabolic bone diseases J. Clin. Endocrinol. Metab. 85 2000 2355 2363
30. H Hsu D.L Lacey C.R Dunstan I Solovyev A Colombero E Timms H.L Tan G Elliott M.J Kelley I Sarosi L Wang X.Z Xia R Elliott L Chiu T Black S Scully C Capparelli S Morony G Shimamoto M.B Bass W.J Boyle Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand Proc. Natl Acad. Sci. USA 96 1999 3540 3545
31. H.L Judd Hormonal dynamics associated with the menopause Clin. Obstet. Gynecol. 19 1976 775 788
32. S Khosla The effects of androgens on osteoblast function in vitro Mayo Clin. Proc. 75 2000 S51 S54
33. S Khosla L.J Melton III E.J Atkinson W.M O'Fallon Relationship of serum sex steroid levels to longitudinal changes in bone density in young versus elderly men J. Clin. Endocrinol. Metab. 86 2001 3555 3561
34. M Kleerekoper D.A Nelson E.L Peterson M.J Flynn A.S Pawluszka G Jacobsen P Wilson Reference data for bone mass, calciotropic horomones, and biochemical markers of bone remodeling in older (55–75) postmenopausal white and black women J. Bone Miner. Res. 9 1994 1267 1276
35. Y.Y Kong H Yoshida I Sarosi H.L Tan E Timms C Capparelli S Morony A.J Oliveira-dos-Santos G Van A Itie W Khoo A Wakeham C.R Dunstan D.L Lacey T.W Mak W.J Boyle J.M Penninger OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis Nature 397 1999 315 323
36. F Labrie P Diamond L Cusan J.L Gomez A Belanger B Candas Effect of 12-month dehydroepiandrosterone replacement therapy on bone, vagina, and endometrium in postmenopausal women J. Clin. Endocrinol. Metab. 82 1997 3498 3505
37. D.L Lacey E Timms H.L Tan M.J Kelley C.R Dunstan T Burgess R Elliott A Colombero G Elliott S Scully H Hsu J Sullivan N Hawkins E Davy C Capparelli A Eli Y.X Qian S Kaufman I Sarosi V Shalhoub G Senaldi J Guo J Delaney W.J Boyle Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation Cell 93 1998 165 176
38. B.Z Leder M.R Smith M.A Fallon M.L Lee J.S Finkelstein Effects of gonadal steroid suppression on skeletal sensitivity to parathyroid hormone in men J. Clin. Endocrinol. Metab. 86 2001 511 516
39. S.K Lim Y.J Won H.C Lee K.B Huh Y.S Park A PCR analysis of ER alpha and beta mRNA abundance in rats and the effect of ovariectomy J. Bone Miner. Res. 14 1999 1189 1196
40. M Lindberg O Vidal K Andersson B Ryberg C Ohlsson Expression and regulation of osteoprotegerin (OPG) and osteoclast differentiation factor (ODF) in mice J. Bone Miner. Res. 14 1999 F162
41. M.K Lindberg S.E Moverare S Skrtic S Alatalo J Halleen S Mohan J.A Gustafsson C Ohlsson Two different pathways for maintenance of trabecular bone in adult mice J. Bone Miner. Res. 17 2002 555 562
42. C Longcope R.S Baker S.L Hui C.C Johnston Jr Androgen and estrogen dynamics in women with vertebral crush Maturitas 6 1984 309 318
43. R Marcus D Leary D.L Schneider E Shane M Favus C.A Quigley The contribution of testosterone to skeletal development and maintenance: lessons from the androgen insensitivity syndrome J. Clin. Endocrinol. Metab. 85 2000 1032 1037
44. R.S Mathur S.C Landgreve L.O Moody J.P Semmens H.O Williamson The effect of estrogen treatment on plasma concentrations of steroid hormones, gonadotropins, prolactin and sex hormone-binding globulin in post-menopausal women Maturitas 7 1985 129 133
45. V Matkovic T Jelic G.M Wardlaw J.Z Ilich P.K Goel J.K Wright Timing of peak bone mass in Caucasian females and its implication for the prevention of osteoporosis: inference from a cross-sectional model J. Clin. Invest. 93 1994 799 808
46. S Mora V Gilsanz Establishment of peak bone mass Endocrinol. Metab. Clin. North Am. 32 2003 39 63
47. A Morishima M.M Grumbach E.R Simpson C Fisher K Qin Aromatase deficiency in male and female siblings caused by a novel mutation in the physiological role of estrogen J. Clin. Endocrinol. Metab. 80 1995 3689 3698
48. M Need M Horowitz C.J Walker B.E Chatterton I.C Chapman B Nordin E cross-over study of fat-corrected forearm mineral content during nandrolone decanoate therapy for osteoporosis Bone 10 1989 3 6
49. L.O Nilsson A Boman L Savendahl G Grigelioniene C Ohlsson E.M Ritzen J Wroblewski Demonstration of estrogen receptor-beta immunoreactivity in human growth plate cartilage J. Clin. Endocrinol. Metab. 84 1999 370 373
50. Y Onoe C Miyaura H Ohta S Nozawa T Suda Expression of estrogen receptor beta in rat bone Endocrinology 138 1997 4509 4512
51. L.G Raisz B Wiita A Artis A Bowen S Schwartz M Trahiotis K Shoukri J Smith Comparison of the effects of estrogen alone and estrogen plus androgen on biochemical markers of bone formation and resorption in postmenopausal women J. Clin. Endocrinol. Metab. 81 1996 37 43
52. E Seeman The structural and biomechanical basis of the gain and loss of bone strength in women and men Endocrinol. Metab. Clin. North Am. 32 2003 25 38
53. W.S Simonet D.L Lacey C.R Dunstan M Kelley M.S Chang R Luthy H.Q Nguyen S Wooden L Bennett T Boone G Shimamoto M DeRose R Elliott A Colombero H.L Tan G Trail J Sullivan E Davy N Bucay L Renshaw-Gegg T.M Hughes D Hill W Pattison P Campbell W.J Boyle Osteoprotegerin: a novel secreted protein involved in the regulation of bone density Cell 89 1997 309 319
54. N.A Sims S Dupont A Krust P Clement-Lacroix D Minet M Resche-Rigon M Gaillard-Kelly R Baron Deletion of estrogen receptors reveals a regulatory role for estrogen receptors-β in bone remodeling in females but not in males Bone 30 2002 18 25
55. C Slemenda C Longcope M Peacock S Hui C.C Johnston Sex steroids, bone mass, and bone loss: a prospective study of pre-, peri-, and postmenopausal women J. Clin. Invest. 97 1996 14 21
56. C.W Slemenda S.L Hui C.L Longcope C.C Johnston Sex steroids and bone mass. A study of changes about the time of menopause J. Clin. Invest. 80 1987 1261 1269
57. C.W Slemenda C Longcope L Zhou S.L Hui M Peacock C.C Johnston Sex steroids and bone mass in older men: positive associations with serum estrogens and negative associations with androgens J. Clin. Invest. 100 1997 1755 1759
58. E.P Smith J Boyd G.R Frank H Takahashi R.M Cohen B Specker T.C Williams D.B Lubahn K.S Korach Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man N. Engl. J. Med. 331 1994 1056 1061
59. P Taxel D.G Kennedy P.M Fall A.K Willard J.M Clive L.G Raisz The effect of aromatase inhibition on sex steroids, gonadotropins, and markers of bone turnover in older men J. Clin. Endocrinol. Metab. 86 2001 2869 2874
60. D Teegarden W.R Proulx B.R Martin Peak bone mass in young women J. Bone Miner. Res. 10 1995 711 715
61. R.T Turner K.S Hannon L.M Demers J Buchanan N.H Bell Different effects of gonadal function on bone histomorphometry in male and female rats J. Bone Miner. Res. 4 1989 557 563
62. R.T Turner G.K Wakley K.S Hannon Differential effects of androgens on cortical bone histomorphometry in gonadectomized male and female rats J. Orthop. Res. 8 1990 612 617
63. M.C.H Van der Meulen G.S Beaupre D.R Carter Mechanobiologic influences in long bone cross-sectional growth Bone 14 1993 635 642
64. D Vanderschueren E Van Herck A.M.H Suiker W.J Visser L.P Schot K Chung R.S Lucas T.A Einhorn R Bouillon Bone and mineral metabolism in the androgen-resistant (testicular feminized) male rat J. Bone Miner. Res. 8 1993 801 809
65. O Vidal L.-G Kindblom C Ohlsson Expression and localization of estrogen receptor-beta in murine and human bone J. Bone Miner. Res. 14 1999 923 926
66. O Vidal M.K Lindberg K Hollberg D.J Baylink G Andersson D.B Lubahn S Mohan J.A Gustafsson C Ohlsson Estrogen receptor specificity in the regulation of skeletal growth and maturation in male mice Proc. Natl Acad. Sci. USA 97 2000 5474 5479
67. M.P Warren J Brooks-Gunn L.H Hamilton W.L Fiske W.G Hamilton Scoliosis and fractures in young ballet dancers N. Engl. J. Med. 314 1986 1348 1353
68. N.B Watts M Notelovitz M.C Timmons Comparison of oral estrogens and estrogens plus androgen on bone mineral density, menopausal symptoms and lipid–lipoprotein profiles in surgical menopause Obstet. Gynecol. 85 1995 529 537
69. S.H Windahl K Hollberg O Vidal J.A Gustafsson C Ohlsson G Andersson Female estrogen receptor beta−/− mice are partially protected against age-related trabecular bone loss J. Bone Miner. Res. 16 2001 1388 1398
70. S.H Windahl O Vidal G Andersson J.A Gustafsson C Ohlsson Increased cortical bone mineral content but unchanged trabeulcar bone mineral density in female ER β(−/−) mice J. Clin. Invest. 104 1999 895 901
71. M Zachmann A Prader E.H Sobel J.F Crigler Jr E.M Ritzen M Atares A Ferrandez Pubertal growth in patients with androgen insensitivity: indirect evidence for the importance of estrogen in pubertal growth of girls J. Pediatr. 108 1986 694 697
72. J.V Zborowski J.A Cauley E.O Talbott D.S Guzick S.J Winters Bone mineral density, androgens, and the polycystic ovary: the complex and controversial issue of androgenic influence in female bone J. Clin. Endocrinol. Metab. 85 2000 3496 3506
73. X.Z Zhang D.N Kalu B Erbas J.L Hopper E Seeman The effect of gonadectomy on bone size, mass and volumetric density in growing rats may be gender- site-, and growth hormone-dependent J. Bone Miner. Res. 14 1999 802 809
74. B Zumoff G.W Strain L.K Miller W Rosner Twenty-four hour mean plasma concentration declines with age in normal premenopausal women J. Clin. Endocrinol. Metab. 80 1995 1429 1430