A PCR analysis of ERα and ERβ mRNA abundance in rats and the effect of ovariectomy

Journal of Bone and Mineral Research

Volumn 14, Issue 7, 1999, Pages 1189-1196

  Lim, S K ^a   Won, Y J ^a   Lee, H C ^a   Huh, K B ^a   Park, Y S ^b  

^a Yonsei University College of Medicine   (South Korea)

^b Seoul Clinical Laboratories   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW CELL; CALCIUM HOMEOSTASIS; COMPETITIVE INHIBITION; CONTROLLED STUDY; CORTICAL BONE; MESSENGER RNA SYNTHESIS; NONHUMAN; OVARIECTOMY; POLYMERASE CHAIN REACTION; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRABECULAR BONE; ANIMAL; ANTIBODY SPECIFICITY; BONE; CELL CULTURE; FEMALE; METABOLISM; OVARY; SPRAGUE DAWLEY RAT; STROMA CELL;

ESTROGEN RECEPTOR; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; PRIMER DNA;

ANIMALS; BONE AND BONES; BONE MARROW CELLS; CELLS, CULTURED; DNA PRIMERS; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FEMALE; ORGAN SPECIFICITY; OVARIECTOMY; OVARY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STROMAL CELLS;

EID: 0032587903     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1999.14.7.1189     Document Type: Article

References (30)

1. Milgrom E, Savouret JF, Mantel A, Perrot-Applanat M, Delabre K, Lescop P 1997 Promotor-and cell-specific responses to sex steroids. Osteoporos Int 7 (Suppl 1):S23-S28.
2. Kuiper GG, Enmark E, Pelto-Huikko M, Nilsson S, Gustafsson JA 1996 Cloning of a novel estrogen receptor expressed in rat prostate and ovary. Proc Natl Acad Sci USA 93:5925-5930.
3. Mosselman S, Polman J, Dijkema R 1996 ERβ: Identification and characterization of a novel human estrogen receptor. FEBS Lett 392:49-53.
4. Tremblay GB, Tremblay A, Copeland NG, Gilbert DJ, Jenkins NA, Labrie F, Giguere V 1997 Cloning, chromosomal localization, and functional analysis of the murine estrogen receptor β. Mol Endocrinol 11:353-365.
5. Pennisi E 1997 Differing roles found for estrogen's two receptors. Science 277:1439.
6. Ogawa S, Inoue S, Watanabe T, Hiroi H, Orimo A, Hosoi T, Ouchi Y, Muramastsu M 1997 Molecular cloning and functional analysis of human estrogen receptor β2. J Bone Miner Res 12 (Suppl 1):S165.
7. Lindsay R, Cosman F 1997 Skeletal effects of estrogen analogs. Osteoporos Int 7 (Suppl 1):S40-S42.
8. Kangas L 1992 Agonistic and antagonistic effects of antiestrogens in different target organs. Acta Oncol 31:143-146.
9. Pan LC, Ke HZ, Simmons HA, Crawford DT, Chidsey-Frink KL, McCurdy SP, Schafer JR, Kimbro KS, Taki M, Korach KS, Thomson DD 1997 Estrogen receptor-alpha knockout (ERKO) mice lose trabecular and cortical bone following ovariectomy. J Bone Miner Res 12 (Suppl 1):S134.
10. Paech K, Webb P, Kuipper GGJM, Nilsson S, Gustafsson J-A, Kushner PJ, Scanlan TS 1997 Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. Science 277:1508-1510.
11. Beekman JM, Allan GF, Tsai SY, Tsai M-J, O'Malley BW 1993 Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Mol Endocrinol 7:1266-1274.
12. Cowley SM, Hoare S, Mosselman S, Parker MG 1997 Estrogen receptors alpha and beta form heterodimers on DNA. J Biol Chem 272:19858-19862.
13. Kim GS, Kim CH, Choi CS, Park JY, Lee KU 1997 Involvement of different second messengers in parathyroid hormone-and interleukin-1-induced interleukin-6 and interleukin-11 production in human bone marrow stromal cells. J Bone Miner Res 12:896-902.
14. Kuiper GG, Carlsson B, Grandien K, Enmark E, Haggblad J, Nilsson S, Gustafsson JA 1997 Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptor α and β. Endocrinology 138:863-870.
15. Grandien KF, Berkenstam A, Nilsson S, Gustafsson JA 1993 Localization of DNAse I hypersensitive sites in the human estrogen receptor gene correlates with the transcriptional activity of two differentially used promoters. J Mol Endocrinol 10:269-277.
16. Stewart PJ, Stern PH 1986 Effects of the antiestrogens tamoxifen and clomiphene on bone resorption in vitro. Endocrinology 118:125-131.
17. Pettersson K, Grandien K, Kuipper GGJM, Gustafsson J-A 1997 Mouse estrogen receptor βs forms estrogen response element-binding heterodimers with estrogen receptor α. Mol Endocrinol 11:1486-1496.
18. Enmark E, Pelto-huikko M, Grandien K, Lagercrantz S, Lagercrantz J, Fried G, Nordenskjold M, Gustanfsson J-A 1998 Human estrogen receptor β-gene structure, chromosomal localization, and expression pattern. J Clin Endocrinol Metab 82:4258-4265.
19. Ohashi T, Kusuhara S 1993 Immunoelectron microscopic detection of estrogen target cells in the bone marrow of estrogen treated male Japanese quail. Bone Miner 20:31-39.
20. Onoe Y, Miyaura C, Ohata H, Nozawa S, Suda T 1997 Expression of estrogen receptor β in rat bone. Endocrinology 138:4509-4512.
21. Smithson G, Medina K, Ponting I, Kincade PW 1995 Estrogen suppresses stromal cell-dependent lymphopoiesis in culture. J Immunol 155:3409-3417.
22. Pacifici R 1996 Estrogen, cytokines, and pathogenesis of post-menopausal osteoporosis. J Bone Miner Res 11:1043-1051.
23. Miyaura C, Onoe Y, Inada M, Maki K, Ikuta K, Ito M, Suda T 1997 Increased B-lymphopoiesis by IL-7 treatment induces bone loss in mice with intact ovarian function: Similarity to estrogen deficiency. J Bone Miner Res 12 (Suppl 1):S126.
24. Bhat HK, Hacker HJ, Bannasch P, Thompson EA, Liehr JG 1993 Localization of estrogen receptors in interstitial cells of hamster kidney and in estradiol-induced renal tumors as evidence of the mesenchymal origin of this neoplasm. Cancer Res 53:5447-5551.
25. Salih MA, Sim SH, Kalu DN 1996 Putative intestinal estrogen receptor: Evidence for regional differences. Mol Cell Endocrinol 121:47-55.
26. Jaklic BR, Rushin J, Ghosh BC 1995 Estrogen and progesterone receptors in thyroid lesions. Ann Surg Oncol 2:429-434.
27. Korach KS 1994 Insights from the study of animals lacking functional estrogen receptor. Science 266:1524-1527.
28. Smith EP, Boyd J, Frank GR, Takahashi H, Cohen RM, Specker B, Williams TC, Lubahn DB, Korach KS 1994 Estrogen resistance caused by a mutation in the estrogen receptor gene in men. N Engl J Med 331:1056-1061.
29. Delvin EE, Lopez V, Levy E, Menard D 1996 Calcitriol differentially modulates mRNA encoding calcitriol receptors and calcium-binding protein 9 kDa in human fetal jejunum. Biochem Biophys Res Commun 224:544-548.
30. Stein B, Yang MX 1995 Repression of the interleukin-6 promotor by estrogen receptor is mediated by NF-κB and C/EBPβs. Mol Cell Biol 15:4971-4979.