Vitamin D insufficiency - Possible influence on the development of autoimmune diseases;D-vitamin-insufficiens - En mulig ætiologisk faktor ved autoimmune sygdomme

Ugeskrift for Laeger

Volumn 169, Issue 43, 2007, Pages 3655-3660

  Jørgensen, Søren Peter ^a   Bartels, Lars Erik ^b   Agnholt, Jørgen ^b   Glerup, Henning ^b   Nielsen, Søren Lyhne ^b   Hvas, Christian Lodberg ^b   Dahlerup, Jens F ^b  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D;

ANIMAL; AUTOIMMUNE DISEASE; BIOSYNTHESIS; ENTERITIS; HUMAN; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; METABOLISM; MOUSE; MULTIPLE SCLEROSIS; REVIEW; RHEUMATOID ARTHRITIS; VITAMIN D DEFICIENCY;

ANIMALS; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; DIABETES MELLITUS, TYPE 1; HUMANS; INFLAMMATORY BOWEL DISEASES; MICE; MULTIPLE SCLEROSIS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 36049042064     PISSN: 00415782     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Mosekilde L, Brot C, Hyldstrup L et al. D-vitaminstatus i den danske befolkning bør forbedres. Ugeskr Læger 2005;167:895-7.
2. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr 2004;80:1678-88.
3. Vieth R, Chan PC, MacFarlane GD. Efficacy and safety of vitamin D3 intake exceeding the lowest observed adverse effect level. Am J Clin Nutr 2001;73:288-94.
4. Sharma OP. Hypercalcemia in granulomatous disorders: a clinical review. Curr Opin Pulm Med 2000;6:442-7.
5. Veldman CM, Cantorna MT, DeLuca HF. Expression of 1,25-dihydroxyvitamin D(3) receptor in the immune system. Arch Biochem Biophys 2000;374:334-8.
6. Barrat FJ, Cua DJ, Boonstra A et al. In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med 2002;195:603-16.
7. Muller K, Haahr PM, Diamant M et al. 1,25-dihydroxyvitamin D3 inhibits cytokine production by human blood monocytes at the post-transcriptional level. Cytokine 1992;4:506-12.
8. Cippitelli M, Santoni A. Vitamin D3: A transcriptional modulator of the interferon-ã gene. Eur J Immunol 1998;28:3017-30.
9. Boonstra A, Barrat FJ, Crain C et al. 1,25-dihydroxyvitamin D3 has a direct effect on naive CD4+ T cells to enhance the development of Th2 cells. J Immunol 2001;167:4974-80.
10. Fritsche J, Mondal K, Ehrnsperger A et al. Regulation of 25-hydroxyvitamin D3-1á-hydroxylase and production of 1,25-dihydroxyvitamin D3 by human dendritic cells. Blood 2003;102:3314-6.
11. Pedersen AE, Gad M, Walter MR et al. Induction of regulatory dendritic cells by dexamethasone and 1alpha,25-Dihydroxyvitamin D3. Immunol Lett 2004;91:63-9.
12. Van Halteren AG, Tysma OM, van Etten E et al. 1alpha,25-dihydroxyvitamin D3 or analogue treated dendritic cells modulate human autoreactive T cells via the selective induction of apoptosis. J Autoimmun 2004;23:233-9.
13. Shivananda S, Lennard-Jones J, Logan R et al. Incidence of inflammatory bowel disease across Europe: is there a difference between north and south? Results of the European Collaborative Study on Inflammatory Bowel Disease (EC-IBD). Gut 1996;39:690-7.
14. Nerich V, Monnet E, Etienne A et al. Geographical variations of inflammatory bowel disease in France: a study based on national health insurance data. Inflamm Bowel Dis 2006;12:218-26.
15. Vind I, Vieira A, Hougs L et al. NOD2/CARD15 gene polymorphisms in Crohn's disease: a genotype-phenotype analysis in Danish and Portuguese patients and controls. Digestion 2005;72:156-63.
16. van Halteren AG, van Etten E, de Jong EC et al. Redirection of human autoreactive T-cells upon interaction with dendritic cells modulated by TX527, an analog of 1,25 dihydroxyvitamin D3. Diabetes 2002;51:2119-25.
17. McCarthy D, Duggan P, O'Brien M et al. Seasonality of vitamin D status and bone turnover in patients with Crohn's disease. Aliment Pharmacol Ther 2005;21:1073-83.
18. Cantorna MT, Munsick C, Bemiss C et al. 1,25-dihydroxycholecalciferol prevents and ameliorates symptoms of experimental murine inflammatory bowel disease. J Nutr 2000;130:2648-52.
19. Froicu M, Weaver V, Wynn TA et al. A crucial role for the vitamin D receptor in experimental inflammatory bowel diseases. Mol Endocrinol 2003;17:2386-92.
20. Tuomilehto J, Karvonen M, Pitkaniemi J et al. Record-high incidence of Type I (insulin-dependent) diabetes mellitus in Finnish children. The Finnish Childhood Type I Diabetes Registry Group. Diabetologia 1999;42:655-60.
21. Hypponen E, Laara E, Reunanen A et al. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet 2001;358:1500-3.
22. Green A, Patterson CC. Trends in the incidence of childhood-onset diabetes in Europe 1989-1998. Diabetologia 2001;44(suppl 3):B3-B8.
23. Pozzilli P, Manfrini S, Crino A et al. Low levels of 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 in patients with newly diagnosed type 1 diabetes. Horm Metab Res 2005;37:680-3.
24. Passa P. Diabetes trends in Europe. Diabetes Metab Res Rev 2002;18(suppl 3):S3-S8.
25. Makino S, Kunimoto K, Muraoka Y et al. Breeding of a non-obese, diabetic strain of mice. Jikken Dobutsu 1980;29:1-13.
26. Mathieu C, Waer M, Laureys J et al. Prevention of autoimmune diabetes in NOD mice by 1,25 dihydroxyvitamin D3. Diabetologia 1994;37:552-8.
27. Zella JB, McCary LC, DeLuca HF. Oral administration of 1,25-dihydroxyvitamin D3 completely protects NOD mice from insulin-dependent diabetes mellitus. Arch Biochem Biophys 2003;417:77-80.
28. Rosati G. The prevalence of multiple sclerosis in the world: an update. Neurol Sci 2001;22:117-39.
29. Soilu-Hanninen M, Airas L, Mononen I et al. 25-Hydroxyvitamin D levels in serum at the onset of multiple sclerosis. Mult Scler 2005;11:266-71.
30. Munger KL, Zhang SM, O'Reilly E et al. Vitamin D intake and incidence of multiple sclerosis. Neurology 2004;62:60-5.
31. Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxyvitamin D3 reversibly blocks the progression of relapsing encephalomyelitis, a model of multiple sclerosis. Proc Natl Acad Sci U S A 1996;93:7861-4.
32. Spach KM, Hayes CE. Vitamin D3 confers protection from autoimmune encephalomyelitis only in female mice. J Immunol 2005;175:4119-26.
33. Garcion E, Sindji L, Nataf S et al. Treatment of experimental autoimmune encephalomyelitis in rat by 1,25-dihydroxyvitamin D3 leads to early effects within the central nervous system. Acta Neuropathol (Berl) 2003;105:438-48.
34. Symmons DP. Epidemiology of reumatoid artritis: determinants of onset, persistence and outcome. Best Pract Res Clin Rheumatol 2002;16:707-22.
35. Merlino LA, Curtis J, Mikuls TR et al. Vitamin D intake is inversely associated with reumatoid artritis: results from the Iowa Women's Health Study. Arthritis Rheum 2004;50:72-7.
36. Cantorna MT, Hayes CE, DeLuca HF. 1,25-Dihydroxycholecalciferol inhibits the progression of arthritis in murine models of human arthritis. J Nutr 1998;128:68-72.
37. Goldberg P, Fleming MC, Picard EH. Multiple sclerosis: decreased relapse rate through dietary supplementation with calcium, magnesium and vitamin D. Med Hypotheses 1986;21:193-200.
38. Mahon BD, Gordon SA, Cruz J et al. Cytokine profile in patients with multiple sclerosis following vitamin D supplementation. J Neuroimmunol 2003;134:128-32.
39. Brohult J, Jonson B. Effects of large doses of calciferol on patients with reumatoid artritis. A double-blind clinical trial. Scand J Rheumatol 1973;2:173-6.
40. Andjelkovic Z, Vojinovic J, Pejnovic N et al. Disease modifying and immunomodulatory effects of high dose 1á-OH- vitamin D3 in reumatoid artritis patients. Clin Exp Rheumatol 1999;17:453-6.