Mycotoxin fumonisin B1 alters cellular redox balance and signalling pathways in rat liver and kidney

Toxicology

Volumn 242, Issue 1-3, 2007, Pages 31-38

  Rumora, Lada ^a   Domijan, Ana Marija ^b   Grubišić, Tihana Žanić ^a   Peraica, Maja ^b  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b INSTITUTE FOR MEDICAL RESEARCH AND OCCUPATIONAL HEALTH   (Croatia)

Author keywords

Fumonisin B1; Glutathione; Heat shock proteins; Kidney; Liver; Mitogen activated protein kinases

Indexed keywords

FUMONISIN B1; GLUTATHIONE; HEAT SHOCK PROTEIN 25; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYCOTOXIN; STRESS ACTIVATED PROTEIN KINASE; FUMONISIN; HEAT SHOCK PROTEIN; HSPB1 PROTEIN, RAT; TUMOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; KIDNEY; LIVER; MALE; NONHUMAN; OXIDATION REDUCTION STATE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; TOXICITY TESTING; TOXIN ANALYSIS; UPREGULATION; WISTAR RAT; ANIMAL; DRUG EFFECT; ENZYMOLOGY; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; TIME;

RATTUS; RATTUS NORVEGICUS; ZEA MAYS;

ANIMALS; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FUMONISINS; GLUTATHIONE; HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; INJECTIONS, INTRAPERITONEAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KIDNEY; LIVER; MALE; MYCOTOXINS; NEOPLASM PROTEINS; OXIDATION-REDUCTION; OXIDATIVE STRESS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, WISTAR; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 36048976273     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.09.006     Document Type: Article

References (42)

1. Ainbinder E., Bergelson S., Pinkus R., and Daniel V. Regulatory mechanisms involved in activator-protein-1 (AP-1)-mediated activation of glutathione-S-transferase gene expression by chemical agents. Eur. J. Biochem. 243 (1997) 49-57
2. Asea A. Stress proteins and initiation of immune response: chaperokine activity of hsp72. Exerc. Immunol. Rev. 11 (2005) 34-45
3. 10, l-carnitine, α-tocopherol and selenium. Pharmacol. Res. 40 (1999) 459-467
4. 1 administered intraperitoneally to male Sprague-Dawley rats. Food Chem. Toxicol. 33 (1995) 653-665
5. 1 to B6C3F1 mice: a 14-day gavage study. Food Chem. Toxicol. 35 (1997) 981-989
6. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72 (1976) 248-254
7. Chang L., and Karin M. Mammalian MAP kinase signalling cascades. Nature 410 (2001) 37-40
8. Coppola S., and Ghibelli L. GSH extrusion and the mitochondrial pathway of apoptotic signalling. Biochem. Soc. Trans. 28 (2000) 56-61
9. Curtin J.F., Donovan M., and Cotter T.G. Regulation and measurement of oxidative stress in apoptosis. J. Immunol. Methods 265 (2002) 49-72
10. 1-treated rats. Toxicology 222 (2006) 53-59
11. Ellman G.L. A colorimetric method for determining low concentrations of mercaptans. Arch. Biochem. Biophys. 74 (1958) 443-450
12. Eyer P., Worek F., Kiderlen D., Šinko G., Štuglin A., Simeon-Rudolf V., and Reiner E. Molar absorption coefficients for the reduced Ellman reagent: reassessment. Anal. Biochem. 312 (2003) 224-227
13. Ferns G., Shams S., and Shafi S. Heat shock protein 27: its potential role in vascular disease. Int. J. Exp. Pathol. 87 (2006) 253-274
14. Filomeni G., Rotilio G., and Ciriolo M.R. Cell signalling and the glutathione redox system. Biochem. Pharmacol. 64 (2002) 1057-1064
15. Filomeni G., Rotilio G., and Ciriolo M.R. Disulfide relays and phosphorylative cascades: partners in redox-mediated signalling pathways. Cell Death Differ. 12 (2005) 1555-1563
16. 1. Neurochem. Res. 27 (2002) 345-351
17. 1. Food Chem. Toxicol. 40 (2002) 25-31
18. Han D., Hanawa N., Saberi B., and Kaplowitz N. Mechanisms of liver injury. III. Role of glutathione redox status in liver injury. Am. J. Gastrointest. Liver Physiol. 291 (2006) G1-G7
19. IARC. Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene. IARC Monographs on the Overall Evaluations of Carcinogenicity to Humans vol. 82 (2002), International Agency for Research on Cancer, Lyon pp. 301-366
20. 1. Chem. Biol. Interact. 145 (2003) 297-309
21. 1-treated pig kidney cells. J. Biochem. Toxicol. 11 (1996) 121-126
22. 1 induces cell proliferation and apoptosis in the rat. Nat. Toxins 4 (1996) 34-41
23. Liu B.H., Wu T.S., Yu F.Y., and Wang C.H. Mycotoxin patulin activates the p38 kinase and JNK signaling pathways in human embryonic kidney cells. Toxicol. Sci. 89 (2006) 423-430
24. Mahlen P., Kretz-Remy C., Préville X., and Arrigo A.P. Human hsp27, Drosophila hsp27 and human αB-crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFα-induced cell death. EMBO J. 15 (1996) 2695-2706
25. Matsuzawa A., and Ichijo H. Stress-responsive protein kinases in redox-regulated apoptosis signaling. Antioxid. Redox Signal. 7 (2005) 472-481
26. Merrill A.H., Sullards M.C., Wang E., Voss K.A., and Riley R.T. Sphingolipid metabolism: roles in signal transduction and disruption by fumonisins. Environ. Health Perspect. 109 (2001) 283-289
27. Morales A., García-Ruiz C., Miranda M., Marí M., Colell A., Ardite E., and Fernández-Checa J.C. Tumor necrosis factor increases hepatocellular glutathione by transcriptional regulation of the heavy subunit chain of γ-glutamylcysteine synthetase. J. Biol. Chem. 272 (1997) 30371-30379
28. Nadeau S.I., and Landry J. Mechanisms of activation and regulation of the heat shock-sensitive signalling pathways. Adv. Exp. Med. Biol. 594 (2007) 100-113
29. Park J.W., Moon C., Yun S., Kim S.Y., Bae Y.C., Chun M.H., and Moon J.I. Differential expression of heat shock protein mRNAs under in vivo glutathione depletion in the mouse retina. Neurosci. Lett. 413 (2007) 260-264
30. 2 phosphorylation, the arachidonic acid cascade and cAMP production. Carcinogenesis 20 (1999) 1683-1688
31. Rahman I., and MacNee W. Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease. Lung Cell. Mol. Physiol. 21 (1999) L1067-L1088
32. Rokutan K., Hirakawa T., Teshima S., Honda S., and Kishi K. Glutathione depletion impairs transcriptional activation of heat shock genes in primary cultures of guinea pig gastric mucosal cells. J. Clin. Invest. 97 (1996) 2242-2250
33. 1 on rabbit kidney RK13 cell line. Arch. Toxicol. 76 (2002) 55-61
34. Schmitt E., Gehrmann M., Brunet M., and Garrido C. Intracellular and extracellular functions of heat shock proteins: repercussions in cancer therapy. J. Leukoc. Biol. 81 (2007) 15-27
35. 1, beauvericin and ochratoxin A. Basic Clin. Pharmacol. Toxicol. 100 (2007) 157-164
36. 1 induced apoptosis in murine primary hepatocytes. J. Biochem. Mol. Toxicol. 19 (2005) 359-367
37. 1 in continuous human and rodent neural cell cultures. Free Radic. Res. 38 (2004) 933-942
38. Sumbayev V.V., and Yasinska I.M. Regulation of MAP kinase-dependent apoptotic pathway: implication of reactive oxygen and nitrogen species. Arch. Biochem. Biophys. 436 (2005) 406-412
39. Wang E., Norred W.P., Bacon C.W., Riley R.T., and Merrill A.H. Inhibition of sphingolipid biosynthesis by fumonisins. J. Biol. Chem. 22 (1990) 14486-14490
40. 1. Biochem. Biophys. Res. Commun. 227 (1996) 622-627
41. Wu T.S., Yu F.Y., Su C.C., Kan J.C., Chung C.P., and Liu B.H. Activation of ERK mitogen-activated protein kinase in human cells by the mycotoxin patulin. Toxicol. Appl. Pharmacol. 207 (2005) 103-111
42. Zhuang S., and Schnellmann R.G. A death-promoting role for extracellular signal-regulated kinase. J. Pharmacol. Exp. Ther. 319 (2006) 991-997