DNA damage in astrocytes exposed to fumonisin B1

Neurochemical Research

Volumn 27, Issue 4, 2002, Pages 345-351

  Galvano, F ^a   Campisi, A ^b   Russo, A ^b   Galvano, G ^b   Palumbo, M ^b   Renis, M ^b   Barcellona, M L ^b   Perez Polo, J R ^c   Vanella, A ^b  

^a UNIVERSITY MEDITERRANEA OF REGGIO CALABRIA   (Italy)

^b UNIVERSITY OF CATANIA   (Italy)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Astrocytes; Caspase 3; DNA damage; Fumonisin B1; Heat Shock Protein

Indexed keywords

CASPASE 3; FUMONISIN B1; HEAT SHOCK PROTEIN 70; SPHINGANINE; SPHINGOLIPID; SPHINGOSINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; ASTROCYTE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVITY; ENZYME INHIBITION; GENOTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, NEWBORN; ASTROCYTES; CARBOXYLIC ACIDS; CARCINOGENS, ENVIRONMENTAL; CELL SURVIVAL; CELLS, CULTURED; COMET ASSAY; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FUMONISINS; FUSARIUM; MYCOTOXINS; RATS; RATS, WISTAR; TIME FACTORS;

ANIMALIA; FUNGI; FUSARIUM; FUSARIUM PROLIFERATUM; GIBBERELLA FUJIKUROI; SPHINGIODEA; ZEA MAYS;

EID: 0036204104     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1014971515377     Document Type: Article

References (48)

1. Toxicity and role of fumonisins in animal diseases and human esophageal cancer
2. Fumonisins
3. Fumonisins. History, worldwide occurrence and impact
4. Survey of fumonisin production by Fusarium isolated from cereals in Europe
5. Report on an IARC working group meeting on some naturally occurring substances
6. Mechanism of fumonisin toxicity and carcinogenesis
7. Inhibition of sphingolipid biosynthesis by fumonisins: Implications for diseases associated with Fusarium moniliforme
8. Sphingolipids-the enigmatic lipid class: Biochemistry, physiology, and pathophysiology
9. 1 impairs myelin formation in aggregating brain cell culture
10. 1 in CV-1 cells
11. Programmed cell death in cortical chick embryo astrocytes is associated with activation of protein kinase PK60 and ceramide formation
12. 1 in isolated rat liver nuclei
13. Growth and cultivation of dissociated neurons and glial cells from embryonic chick, rat and human brain in flask culture
14. Localization of the fibrillary acidic protein in astrocytes by immunofluorescence
15. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
16. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
17. Glutamate toxicity in immature cortical neurons precedes development of glutamate receptor currents
18. Ethanol increases cythochrome P-450 2E1 and induces oxidative stress in astrocytes
19. 4
20. Glutamine synthetase activity and HSP70 levels in cultured rat astrocytes: Effect of 1-octadecyl-2-methyl-rac-glicero-3-phosphocoline
21. A microgel electrophoresis technique for the direct quantitation of DNA damage and repair in individual fibroblasts cultured on microscope slides
22. Fumonisin inhibits sphingosine (sphinganine)N-acyltransferase and de novo sphingolipid biosynthesis in cultured neurons in situ
23. Inhibition of sphingosine biosynthesis by fumonisins
24. De novo-synthesized ceramide signals apoptosis in astrocytes via extracellular signal-regulated kinase
25. Regulation of sphingolipid metabolism during neuronal growth and development
26. Early fumonisin B1 toxicity in relation to disrupted sphingolipid metabolism in male BALB/c mice
27. 1 in human keratinocytes, fibroblasts, esophageal epithelial cells and hepatoma cells
28. Fumonisin and Alternata lycopersici toxins; sphinganine analog mycotoxins induce apoptosis in monkey kidney cells
29. DNA damage by mycotoxins
30. 10, L-carnitine, alpha-tocopherol and selenium
31. 1, moniliformin and vomitoxin in bacteria and in primary cultures of rat hepatocytes
32. 6 glioma cells
33. 1
34. 1: Implication of lipid peroxidation and inhibition of protein and DNA synthesis
35. 1-induced toxicity in primary rat hepatocytes and rat liver in vivo
36. 1 on lipid peroxidation in membranes
37. 1 in C6 glioma cells
38. Fumonisins-novel mycotoxins with cancer promoting activity produced by Fusarium moniliforme
39. 1, a carcinogenic mycotoxin produced by Fusarium moniliforme
40. Protein-mediated protein maturation in eukariotes
41. Effects of low culture temperature on the induction of HSP-70 m-RNA and accumulation of HSP-70 and HSP-105 in mouse FM3A cells
42. Prevention of protein denaturation under heat stress by the chaperonine HSP-60
43. Antioxidant actions of plant foods: Use of oxidative DNA damage as a tool for studying antioxidant efficacy
44. The role of inducible 70 Kda heat shock protein in cell cycle control, differentiation and apoptotic cell death of the human myeloid leukemic HL-60 cells
45. 1, a mycotoxin contaminant of cereal grains, and inducer of apoptosis via the tumour necrosis factor pathway and caspase activation
46. Acylation of naturally occurring and synthetic 1-Deoxysphinganines by ceramide synthase
47. Elevated sphingoid bases and complex sphingolipid depletion as contributing factors in fumonisin-induced cytotoxicity
48. The role of sphingolipids in the maintenance of fibroblast morphology