Major human γ-aminobutyrate transporter: In silico prediction of substrate efficacy

Biochemical and Biophysical Research Communications

Volumn 364, Issue 4, 2007, Pages 952-958

  Palló, Anna ^a   Bencsura, Ákos ^a   Héja, László ^a   Beke, Tamás ^b   Perczel, András ^b   Kardos, Julianna ^a   Simon, Ágnes ^a  

^a CHEMICAL RESEARCH CENTER   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

Author keywords

Aminobutyrate; Crystal structure based homology modeling; Effective conformation; Human transporter; Molecular dynamics; Substrate docking

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID CARRIER; BACLOFEN; ENZYME INHIBITOR; GLUTAMINE; GUVACINE; LEUCINE; NIPECOTIC ACID;

ARTICLE; LIGAND BINDING; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING;

BINDING SITES; COMPUTER SIMULATION; GABA PLASMA MEMBRANE TRANSPORT PROTEINS; GAMMA-AMINOBUTYRIC ACID; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY;

EID: 36048960873     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.108     Document Type: Article

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