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Volumn 364, Issue 4, 2007, Pages 743-747

Ethanol stimulates bile acid formation in primary human hepatocytes

Author keywords

Bile acid synthesis; CYP7A1; Ethanol; Methanol; Primary hepatocytes

Indexed keywords

ALCOHOL; BILE ACID; CHENODEOXYCHOLIC ACID; CHOLESTANETRIOL 26 MONOOXYGENASE; CHOLESTEROL; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLIC ACID; CYTOCHROME P450; CYTOCHROME P450 6B1; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 36048957994     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.039     Document Type: Article
Times cited : (21)

References (22)
  • 1
    • 1242269851 scopus 로고    scopus 로고
    • Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms
    • Chiang J.Y. Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. J. Hepatol. 40 (2004) 539-551
    • (2004) J. Hepatol. , vol.40 , pp. 539-551
    • Chiang, J.Y.1
  • 2
    • 0037790917 scopus 로고    scopus 로고
    • The enzymes, regulation, and genetics of bile acid synthesis
    • Russell D.W. The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 72 (2003) 137-174
    • (2003) Annu. Rev. Biochem. , vol.72 , pp. 137-174
    • Russell, D.W.1
  • 3
  • 5
    • 0030003833 scopus 로고    scopus 로고
    • Effects of alcohol on plasma lipoprotein metabolism
    • Frohlich J.J. Effects of alcohol on plasma lipoprotein metabolism. Clin. Chim. Acta 246 (1996) 39-49
    • (1996) Clin. Chim. Acta , vol.246 , pp. 39-49
    • Frohlich, J.J.1
  • 6
    • 0021215560 scopus 로고
    • Effects of alcohol on plasma lipoproteins and cholesterol and triglyceride metabolism in man
    • Crouse J.R., and Grundy S.M. Effects of alcohol on plasma lipoproteins and cholesterol and triglyceride metabolism in man. J. Lipid Res. 25 (1984) 486-496
    • (1984) J. Lipid Res. , vol.25 , pp. 486-496
    • Crouse, J.R.1    Grundy, S.M.2
  • 8
    • 35448959360 scopus 로고    scopus 로고
    • D. Katsika, C. Tuvblad, C. Einarsson, P. Lichtenstein, H.U. Marschall, Body mass index, alcohol, tobacco and symptomatic gallstone disease: a Swedish twin study, J. Intern. Med. (2007) in press.
  • 11
    • 0025979461 scopus 로고
    • Ethanol has an acute effect on bile acid biosynthesis in man
    • Axelson M., Mörk B., and Sjövall J. Ethanol has an acute effect on bile acid biosynthesis in man. FEBS Lett. 281 (1991) 155-159
    • (1991) FEBS Lett. , vol.281 , pp. 155-159
    • Axelson, M.1    Mörk, B.2    Sjövall, J.3
  • 12
    • 0023697372 scopus 로고
    • Levels of 7 alpha-hydroxy-4-cholesten-3-one in plasma reflect rates of bile acid synthesis in man
    • Axelson M., Aly A., and Sjövall J. Levels of 7 alpha-hydroxy-4-cholesten-3-one in plasma reflect rates of bile acid synthesis in man. FEBS Lett. 239 (1988) 324-328
    • (1988) FEBS Lett. , vol.239 , pp. 324-328
    • Axelson, M.1    Aly, A.2    Sjövall, J.3
  • 13
    • 0025728697 scopus 로고
    • The plasma level of 7 alpha-hydroxy-4-cholesten-3-one reflects the activity of hepatic cholesterol 7 alpha-hydroxylase in man
    • Axelson M., Björkhem I., Reihner E., and Einarsson K. The plasma level of 7 alpha-hydroxy-4-cholesten-3-one reflects the activity of hepatic cholesterol 7 alpha-hydroxylase in man. FEBS Lett. 284 (1991) 216-218
    • (1991) FEBS Lett. , vol.284 , pp. 216-218
    • Axelson, M.1    Björkhem, I.2    Reihner, E.3    Einarsson, K.4
  • 14
    • 0029666109 scopus 로고    scopus 로고
    • Serum concentrations of 7alpha-hydroxy-4-cholesten-3-one reflect bile acid synthesis in humans
    • Sauter G., Berr F., Beuers U., Fischer S., and Paumgartner G. Serum concentrations of 7alpha-hydroxy-4-cholesten-3-one reflect bile acid synthesis in humans. Hepatology 24 (1996) 123-126
    • (1996) Hepatology , vol.24 , pp. 123-126
    • Sauter, G.1    Berr, F.2    Beuers, U.3    Fischer, S.4    Paumgartner, G.5
  • 15
    • 0017119520 scopus 로고
    • Effects of ethanol on bile acid and cholesterol metabolism
    • Nestel P.J., Simons L.A., and Homma Y. Effects of ethanol on bile acid and cholesterol metabolism. Am. J. Clin. Nutr. 29 (1976) 1007-1015
    • (1976) Am. J. Clin. Nutr. , vol.29 , pp. 1007-1015
    • Nestel, P.J.1    Simons, L.A.2    Homma, Y.3
  • 16
    • 0019226759 scopus 로고
    • Phenotypic stability of adult rat hepatocytes in primary monolayer culture
    • Bissell D.M., and Guzelian P.S. Phenotypic stability of adult rat hepatocytes in primary monolayer culture. Ann. NY Acad. Sci. 349 (1980) 85-98
    • (1980) Ann. NY Acad. Sci. , vol.349 , pp. 85-98
    • Bissell, D.M.1    Guzelian, P.S.2
  • 19
    • 0022462380 scopus 로고
    • Bile acid synthesis in man: assay of hepatic microsomal cholesterol 7 alpha-hydroxylase activity by isotope dilution-mass spectrometry
    • Einarsson K., Angelin B., Ewerth S., Nilsell K., and Björkhem I. Bile acid synthesis in man: assay of hepatic microsomal cholesterol 7 alpha-hydroxylase activity by isotope dilution-mass spectrometry. J. Lipid Res. 27 (1986) 82-88
    • (1986) J. Lipid Res. , vol.27 , pp. 82-88
    • Einarsson, K.1    Angelin, B.2    Ewerth, S.3    Nilsell, K.4    Björkhem, I.5
  • 20
    • 0016273833 scopus 로고
    • Utilization of the carbon and hydrogen atoms of ethanol in the biosynthesis of steroids and bile acids
    • Cronholm T., Burlingame A.L., and Sjövall J. Utilization of the carbon and hydrogen atoms of ethanol in the biosynthesis of steroids and bile acids. Eur. J. Biochem. 49 (1974) 497-510
    • (1974) Eur. J. Biochem. , vol.49 , pp. 497-510
    • Cronholm, T.1    Burlingame, A.L.2    Sjövall, J.3
  • 21
    • 0014747728 scopus 로고
    • Effect of ethanol metabolism on redox state of steroid sulphates in man
    • Cronholm T., and Sjövall J. Effect of ethanol metabolism on redox state of steroid sulphates in man. Eur. J. Biochem. 13 (1970) 124-131
    • (1970) Eur. J. Biochem. , vol.13 , pp. 124-131
    • Cronholm, T.1    Sjövall, J.2
  • 22
    • 0015518049 scopus 로고
    • 2) ethanol. Biosynthesis of bile acids and reduction of 3-keto-5-cholanoic acid
    • 2) ethanol. Biosynthesis of bile acids and reduction of 3-keto-5-cholanoic acid. Eur. J. Biochem. 24 (1972) 507-519
    • (1972) Eur. J. Biochem. , vol.24 , pp. 507-519
    • Cronholm, T.1    Makino, I.2    Sjövall, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.