RAC3 nuclear receptor co-activator has a protective role in the apoptosis induced by different stimuli;El coactivador de receptores nucleares rac3 tiene un rol protector de la apoptosis inducida por distintos estimulos

Medicina

Volumn 67, Issue 5, 2007, Pages 465-468

  Colo, Georgina P ^a   Rubio, Maria F ^a   Alvarado, Cecilia V ^a   Costas, Monica A ^a  

^a INSTITUTO DE INVESTIGACIONES MÉDICAS ALFREDO LANARI   (Argentina)

Author keywords

Apoptosis; NF B; Nuclear receptor coactivators

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE; HYDROGEN PEROXIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; SMALL INTERFERING RNA; STEROID HORMONE; STEROID RECEPTOR COACTIVATOR 3; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ACETYLATION; APOPTOSIS; ARTICLE; CARCINOGENESIS; CELL DEATH; CELL NUCLEUS; CELL PROTECTION; CELL STRAIN HEK293; CELL STRAIN K 562; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DRUG TARGETING; ENZYME INHIBITION; HUMAN; HUMAN CELL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT;

APOPTOSIS; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; KIDNEY; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; RAC GTP-BINDING PROTEINS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSCRIPTION FACTORS;

EID: 36048952030     PISSN: 00257680     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Spencer TE, Jenster G, Burcin MM, et al. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature 1997; 389: 194-8.
2. Anzick S, Kononen J, Walker R, et al. AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer. Science 1997; 277: 965-8.
3. Rubio MF, Werbajh S, Cafferata EG, et al. TNF-alpha enhances estrogen-induced cell proliferation of estrogen-dependent breast tumor cells through a complex containing nuclear factor-kappa B. Oncogene 2006; 25: 1367-77.
4. Werbajh S, Nojek I, Lanz R, Costas MA. RAC-3 is a NF-κB coactivator. FEBS Letters 2000; 485: 195-99.
5. Na S, Lee S, Han S, Choi H, Im S, Lee J. SRC-1 interacts with the p50 subunit and coactivates the NF-κB-mediated transactivations. J Biol Chem 1998; 273: 10831-34.
6. Ghosh S, Karin M. Missing pieces in the NF-κB puzzle. Cell 2002; 109: 81-96.
7. Su B, Karin M. Mitogen-activated protein kinase cascades and regulation of gene expression. Curr Opin Immunol 1996; 8: 402-11.
8. Downward J. Ras signalling and apoptosis. Curr Opin Genet Dev 1998; 8: 49-54.
9. Franco DL, Nojek IM, Molinero L, Coso OA, Costas MA. Osmotic stress sensitizes naturally resistant cells to TNF-induced apoptosis. Cell Death Differ 2002; 9: 1090-98.
10. Martelli AM, Nyakern M, Tabellini G, et al. Phosphoinositide 3-kinase/ Akt signaling pathway and its therapeutical implications for human acute myeloid leukemia. Leukemia 2006; 20: 911-28.
11. Zhou G, Hashimoto Y, Kwak I, Tsai SY, Tsai M-J. Role of the steroid receptor coactivator SRC-3 in cell growth. Mol Cell Biol 2003; 23: 7742-55.
12. Hao XS, Hao JH, Liu FT, Newland AC, Jia L. Potential mechanisms of leukemia cell resistance to TRAIL-induced apopotosis. Apoptosis 2003; 8: 601-7.