Analysis of copy number changes suggests chromosomal instability in a minority of large colorectal adenomas

Journal of Pathology

Volumn 213, Issue 3, 2007, Pages 249-256

  Jones, A M ^a   Thirlwell, C ^a   Howarth, K M ^a   Graham, T ^a,b   Chambers, W ^c   Segditsas, S ^a   Page, K M ^b   Phillips, R K S ^d   Thomas, H J W ^d   Sieber, O M ^a   Sawyer, E J ^a   Tomlinson, I P M ^a,e  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^d ST MARK S HOSPITAL   (United Kingdom)

^e QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Colorectal tumours; Copy number changes; Early lesions; Genomic instability

Indexed keywords

ARTICLE; CANCER GROWTH; CHROMOSOMAL INSTABILITY; CHROMOSOME 13; CHROMOSOME 17; CHROMOSOME 18Q; CHROMOSOME 19; CHROMOSOME 1P; CHROMOSOME 21; CHROMOSOME 22; CHROMOSOME 4Q; CHROMOSOME 9Q; CHROMOSOME BREAKAGE; CHROMOSOME DELETION; CHROMOSOME FRAGILE SITE; CHROMOSOME MUTATION; COLORECTAL ADENOMA; COLORECTAL CARCINOMA; COMPARATIVE GENOMIC HYBRIDIZATION; DISEASE COURSE; DNA DAMAGE; DNA MICROARRAY; GENE DELETION; GENE NUMBER; GENETIC ANALYSIS; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MOLECULAR CLONING; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADENOMA; ADENOMATOUS POLYPOSIS COLI; CARCINOMA; CHROMOSOMAL INSTABILITY; CHROMOSOME DELETION; CHROMOSOMES, HUMAN; COLORECTAL NEOPLASMS; DNA, NEOPLASM; GENE DUPLICATION; GENE EXPRESSION PROFILING; HUMANS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 35948974416     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2234     Document Type: Article

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