메뉴 건너뛰기




Volumn 9, Issue 22, 2007, Pages 4595-4598

Solvent-controlled highly selective bis-and monoallylation of active methylene compounds by allyl acetate with palladium(0) nanoparticle

Author keywords

[No Author keywords available]

Indexed keywords


EID: 35948968731     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol702099v     Document Type: Article
Times cited : (64)

References (30)
  • 24
    • 35948962420 scopus 로고    scopus 로고
    • Representative Experimental Procedure for Allylation of Active Methylene Compound (entry 1, Table 1, To a stirred mixture of tetrabutylammonium bromide (323 mg, 1 mmol) and PdCl2 (7 mg, 0.04 mmol) in THF (4 mL) were added allyl acetate (250 mg, 2.5 mmol, acetylacetone (100 mg, 1 mmol, and K2CO3 (414 mg, 3 mmol, The mixture was then heated at reflux for 6 h (TLC, After being cooled THF was evaporated and the residue was extracted with Et2O (3 x 10 mL, The ether extract was washed with brine, dried (Na2SO4, and evaporated to leave the crude product, which was purified by column chromatography over silica gel (ether-hexane 10:90) to afford the pure product, 3,3-diallylpentane-2,4-dione, as a yellow oil (150 mg, 82, IR (neat) 2979, 1739, 1697, 1639 cm-1; 1H NMR (300 MHz, CDCl3) δ 2.06 (s, 6H, 2.61 (d, J, 7.3 Hz, 4H, 5.04-5.11 (m, 4H, 5.42-5.53 m, 2H, 13
    • 2c The solid residue after organic extract containing Pd(0) nanoparticles was reused for subsequent reactions (no loss of efficiency up to three runs).


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.