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Volumn 17, Issue 24, 2007, Pages 6682-6686

Mechanisms of trovafloxacin hepatotoxicity: Studies of a model cyclopropylamine-containing system

Author keywords

Cyclopropylamine; Idiosyncratic drug reaction; K3Fe(CN)6; MPO; NaClO; P450s; Trovafloxacin

Indexed keywords

ALDEHYDE DERIVATIVE; AMINE; CHLORIDE; CYCLOPROPANE DERIVATIVE; CYCLOPROPYLAMINE; CYTOCHROME P450; HEME; HYPOCHLORITE SODIUM; HYPOCHLOROUS ACID; MYELOPEROXIDASE; OXIDIZING AGENT; POTASSIUM FERRICYANIDE; TROVAFLOXACIN; UNCLASSIFIED DRUG;

EID: 35848933222     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2007.10.070     Document Type: Article
Times cited : (17)

References (23)
  • 2
    • 35848967510 scopus 로고    scopus 로고
    • US Food and Drug Administration Website. Public Health Advisory. Trovan (trovafloxacin/alatroflocacin mesylate). June 9, 1999. Available at: http://www.fda.gov/cder/news/trovan.
  • 18
    • 35848963543 scopus 로고    scopus 로고
    • Braish, T. F. U.S. Patent 5,256,791, 1994.
  • 23
    • 35848934938 scopus 로고    scopus 로고
    • note
    • 4OH in acetonitrile (solvent B), and the gradient was as follows: 0 min, 2% B; 4 min, 40% B; 4.5 min, 80% B; 10 min, 100% B; 15 min, 100% B; 16 min, 2% B; and 25 min, 2% B.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.