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Volumn 17, Issue 24, 2007, Pages 6682-6686
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Mechanisms of trovafloxacin hepatotoxicity: Studies of a model cyclopropylamine-containing system
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Author keywords
Cyclopropylamine; Idiosyncratic drug reaction; K3Fe(CN)6; MPO; NaClO; P450s; Trovafloxacin
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Indexed keywords
ALDEHYDE DERIVATIVE;
AMINE;
CHLORIDE;
CYCLOPROPANE DERIVATIVE;
CYCLOPROPYLAMINE;
CYTOCHROME P450;
HEME;
HYPOCHLORITE SODIUM;
HYPOCHLOROUS ACID;
MYELOPEROXIDASE;
OXIDIZING AGENT;
POTASSIUM FERRICYANIDE;
TROVAFLOXACIN;
UNCLASSIFIED DRUG;
ARTICLE;
CARBON NUCLEAR MAGNETIC RESONANCE;
DRUG SYNTHESIS;
LIQUID CHROMATOGRAPHY;
LIVER TOXICITY;
MASS SPECTROMETRY;
NONHUMAN;
OXIDATION;
PROTON NUCLEAR MAGNETIC RESONANCE;
STRUCTURE ACTIVITY RELATION;
ALDEHYDES;
CHROMATOGRAPHY, LIQUID;
CYCLOPROPANES;
FLUOROQUINOLONES;
LIVER;
MAGNETIC RESONANCE SPECTROSCOPY;
MODELS, BIOLOGICAL;
MOLECULAR STRUCTURE;
NAPHTHYRIDINES;
OXIDATION-REDUCTION;
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EID: 35848933222
PISSN: 0960894X
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmcl.2007.10.070 Document Type: Article |
Times cited : (17)
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References (23)
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