Analysis of GNAS mutations in 60 growth hormone secreting pituitary tumors: Correlation with clinical and pathological characteristics and surgical outcome based on highly sensitive GH and IGF-I criteria for remission

Pituitary

Volumn 10, Issue 3, 2007, Pages 275-282

  Freda, Pamela U ^a   Chung, Wendy K ^a   Matsuoka, Naoki ^a   Walsh, Jane E ^b   Kanibir, M Nabi ^a   Kleinman, George ^b   Wang, Yuanjia ^a   Bruce, Jeffrey N ^a   Post, Kalmon D ^b  

^a Columbia University College of Physicians and Surgeons ^*  (United States)

^b MOUNT SINAI MEDICAL CENTER   (United States)

Author keywords

Acromegaly; GNAS mutations; Pituitary adenoma

Indexed keywords

GROWTH HORMONE; SOMATOMEDIN C; SOMATOSTATIN DERIVATIVE; TUMOR MARKER;

ACROMEGALY; ADOLESCENT; ADULT; AGED; AMPLICON; ARTICLE; CLINICAL FEATURE; CODON; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA EXTRACTION; DRUG RESPONSE; FEMALE; GENE MUTATION; GENE SEQUENCE; GROWTH HORMONE SECRETING ADENOMA; HUMAN; HUMAN TISSUE; HYPOPHYSIS ADENOMA; MAJOR CLINICAL STUDY; MALE; MUTATIONAL ANALYSIS; OUTCOME ASSESSMENT; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PREDICTION; PRIORITY JOURNAL; PROTEIN FUNCTION; REMISSION; SEQUENCE ANALYSIS; SOMATIC MUTATION; TUMOR GROWTH;

ACROMEGALY; ADULT; AGED; CELL PROLIFERATION; COHORT STUDIES; FEMALE; GROWTH HORMONE-SECRETING PITUITARY ADENOMA; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; MALE; MIDDLE AGED; MUTATION; PITUITARY NEOPLASMS; REMISSION INDUCTION; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TREATMENT OUTCOME;

EID: 35848933015     PISSN: 1386341X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11102-007-0058-2     Document Type: Article

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