A histological assessment on the distribution of the osteocytic lacunar canalicular system using silver staining

Journal of Bone and Mineral Metabolism

Volumn 25, Issue 6, 2007, Pages 374-382

  Hirose, Satoshi ^a   Li, Minqi ^b   Kojima, Taku ^a,b   De Freitas, Paulo Henrique Luiz ^a,b   Ubaidus, Sobhan ^a,b   Oda, Kimimitsu ^a,b   Saito, Chikara ^a   Amizuka, Norio ^b  

^a NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^b NIIGATA UNIVERSITY   (Japan)

Author keywords

Bone matrix; Bone remodeling; Lacunar canalicular system; Osteocyte; Osteoprotegerin

Indexed keywords

OSTEOPROTEGERIN;

ANIMAL TISSUE; ARTICLE; BONE MATRIX; BONE MINERALIZATION; BONE STRUCTURE; BONE TISSUE; BONE TURNOVER; CARTILAGE; CONTROLLED STUDY; CORTICAL BONE; CYTOPLASM; HISTOLOGY; MALE; MOUSE; NONHUMAN; OSTEOCYTE; OSTEOCYTIC LACUNAR CANALICULAR SYSTEM; PRIORITY JOURNAL; SILVER STAINING; SPINDLE CELL; SURFACE PROPERTY; TRABECULAR BONE;

ACID PHOSPHATASE; ANIMALS; FEMUR; HAVERSIAN SYSTEM; ISOENZYMES; MALE; MICE; MICE, INBRED C57BL; OSTEOBLASTS; OSTEOCLASTS; OSTEOCYTES; OSTEOPROTEGERIN; SILVER STAINING;

EID: 35748962590     PISSN: 09148779     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00774-007-0764-x     Document Type: Article

References (42)

1. AM Parfitt 1977 The cellular basis of bone turnover and bone loss: a rebuttal of the osteocytic resorption-bone flow theory Clin Orthop Relat Res 127 236 247
2. PJ Nijweide EH Burger J Klein-Nulend 2002 The osteocytes JP Bilezikian LG Raize GA Rodan Principles of Bone Biology 2nd edn. Academic Press Orlando
3. J Power N Loveridge N Rushton M Parker J Reeve 2002 Osteocyte density in aging subjects is enhanced in bone adjacent to remodeling haversian systems Bone (NY) 30 859 865
4. ML Knothe Tate JR Adamson AE Tami TW Bauer 2004 The osteocyte Int J Biochem Cell Biol 36 1 8
5. EM Aarden EH Burger PJ Nijweide 1994 Function of osteocytes in bone J Cell Biochem 55 287 299
6. EH Burger J Klein-Nulend 1999 Mechanotransduction in bone: role of the lacuno-canalicular network FASEB J 13 101 112
7. SB Doty 1981 Morphological evidence of gap junctions between bone cells Calcif Tissue Int 33 509 512
8. F Shapiro 1997 Variable conformation of GAP junctions linking bone cells: a transmission electron microscopic study of linear, stacked linear, curvilinear, oval, and annular junctions Calcif Tissue Int 61 285 293
9. HJ Donahue 2000 Gap junctions and biophysical regulation of bone cell differentiation Bone (NY) 26 417 422
10. H Kamioka T Honjo T Takano-Yamamoto 2001 A three-dimensional distribution of osteocyte processes revealed by the combination of confocal laser scanning microscopy and differential interference contrast microscopy Bone (NY) 28 145 149
11. ML Knothe Tate 2003 "Whither flows the fluid in bone?" An osteocyte's perspective J Biomech 36 1409 1424
12. M Lorenz H Plenk Jr 1977 A perfusion method of incubation to demonstrate horseradish peroxidase in bone Histochemistry (Oxf) 153 257 263
13. T Sasaki A Yamaguchi S Higashi S Yoshiki 1985 Uptake of horseradish peroxidase by bone cells during endochondral bone development Cell Tissue Res 239 547 553
14. ML Knothe Tate P Niederer U Knothe 1998 In vivo tracer transport through the lacunocanalicular system of rat bone in an environment devoid of mechanical loading Bone (NY) 22 107 117
15. S Ejiri H Ozawa 1982 Scanning electron microscopic observations of rat tibia using the HCl-collagenase method Arch Histol Jpn 45 399 404
16. Y Sugawara H Kamioka T Honjo K Tezuka T Takano-Yamamoto 2005 Three-dimensional reconstruction of chick calvarial osteocytes and their cell processes using confocal microscopy Bone (NY) 36 877 883
17. J Klein-Nulend A van der Plas CM Semeins NE Ajubi JA Frangos PJ Nijweide EH Burger 1995 Sensitivity of osteocytes to biomechanical stress in vitro FASEB J 9 441 445
18. DL Johnson TN McAllister JA Frangos 1996 Fluid flow stimulates rapid and continuous release of nitric oxide in osteoblasts Am J Physiol 271 1 pt 1 E205 E208
19. L Wang Y Wang Y Han SC Henderson RJ Majeska S Weinbaum MB Schaffler 2005 In situ measurement of solute transport in the bone lacunar-canalicular system Proc Natl Acad Sci U S A 102 11911 19116
20. DR Carter 1987 Mechanical loading history and skeletal biology J Biomech 20 1095 1109
21. R Huiskes H Weinans HJ Grootenboer M Dalstra B Fudala TJ Slooff 1987 Adaptive bone-remodeling theory applied to prosthetic-design analysis J. Biomech 20 1135 1150
22. MG Mullender R Huiskes 1995 Proposal for the regulatory mechanism of Wolff's law J Orthop Res 13 503 512
23. S Mori DB Burr 1993 Increased intracortical remodeling following fatigue damage Bone (NY) 14 103 109
24. DB Burr MR Forwood DP Fyhrie RB Martin MB Schaffler CH Turner 1997 Bone microdamage and skeletal fragility in osteoporotic and stress fractures J Bone Miner Res 12 6 15
25. JG Hazenberg M Freeley E Foran TC Lee D Taylor 2006 Microdamage: a cell transducing mechanism based on ruptured osteocyte processes J Biomech 39 2096 2103
26. BS Noble H Stevens N Loveridge J Reeve 1997 Identification of apoptotic changes in osteocytes in normal and pathological human bone Bone (NY) 20 273 282
27. O Verborgt GJ Gibson MB Schaffler 2000 Loss of osteocyte integrity in association with microdamage and bone remodeling after fatigue in vivo J Bone Miner Res 15 60 67
28. G Gu M Mulari Z Peng TA Hentunen HK Vaananen 2005 Death of osteocytes turns off the inhibition of osteoclasts and triggers local bone resorption Biochem Biophys Res Commun 335 1095 1101
29. FA Schoen 1991 A method to stain decalcified bone without loss of structural detail Biotech Histochem 66 216 219
30. SU Kim 1970 Observations on cerebellar granule cells in tissue culture: a silver and electron microscopic study Z Zellforsch Mikrosk Anat 107 454 465
31. N Amizuka J Shimomura M Li Y Seki K Oda JE Henderson A Mizuno H Ozawa T Maeda 2003 Defective bone remodelling in osteoprotegerin-deficient mice J Electron Microsc 52 503 513
32. M Nakamura N Udagawa S Matsuura M Mogi H Nakamura H Horiuchi N Saito BY Hiraoka Y Kobayashi K Takaoka H Ozawa H Miyazawa N Takahashi 2003 Osteoprotegerin regulates bone formation through a coupling mechanism with bone resorption Endocrinology 144 5441 5449
33. N Amizuka M Yamada JI Watanabe K Hoshi M Fukushi K Oda Y Ikehara H Ozawa 1998 Morphological examination of bone synthesis via direct administration of basic fibroblast growth factor into rat bone marrow Microsc Res Tech 41 313 322
34. K Oda Y Amaya M Fukushi-Irie Y Kinameri K Ohsuye I Kubota S Fujimura J Kobayashi 1999 A general method for rapid purification of soluble versions of glycosylphosphatidylinositol-anchored proteins expressed in insect cells: an application for human tissue-nonspecific alkaline phosphatase J Biochem 126 694 699
35. LE Lanyon 1993 Osteocytes, strain detection, bone modeling and remodeling Calcif Tissue Int 53 S102 S107
36. BR McCreadie SJ Hollister MB Schaffler SA Goldstein 2004 Osteocyte lacuna size and shape in women with and without osteoporotic fracture J Biomech 37 563 572
37. BR McCreadie SJ Hollister 1997 Strain concentrations surrounding an ellipsoid model of lacunae and osteocytes Comput Methods Biomech Biomed Eng 1 61 68
38. HM Frost 1960 Presence of microscopic cracks in vivo in bone Bull Henry Ford Hosp 8 25 35
39. DB Burr 2002 Targeted and nontargeted remodeling Bone (NY) 30 2 4
40. MB Schaffler K Choi C Milgrom 1995 Aging and matrix microdamage accumulation in human compact bone Bone (NY) 17 521 525
41. T Mashiba CH Turner T Hirano MR Forwood DS Jacob CC Johnston DB Burr 2001 Effects of high-dose etidronate treatment on microdamage accumulation and biomechanical properties in beagle bone before occurrence of spontaneous fractures Bone (NY) 29 271 278
42. T Diab KW Condon DB Burr D Vashishth 2006 Age-related change in the damage morphology of human cortical bone and its role in bone fragility Bone (NY) 38 427 431