Pharmacological distribution diagrams: A tool for de novo drug design

Journal of Molecular Graphics

Volumn 14, Issue 5, 1996, Pages 272-276

  Galvez J ^a   Garcia Domenech R ^a   De Gregorio Alapont, C ^a   De Julian Ortiz J V ^a   Popa, L ^a,b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

Author keywords

Charge topological indices; Connectivity indices; Diagrams; Distribution; Pattern recognition; Pharmacokinetic properties; blockers

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA CAROTENE; CLIDANAC; FILIPIN; PROBUCOL;

ARTICLE; DISCRIMINANT ANALYSIS; DRUG ACTIVITY; DRUG DESIGN; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG STRUCTURE; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ADRENERGIC BETA-ANTAGONISTS; COMPUTER GRAPHICS; DISCRIMINANT ANALYSIS; DRUG DESIGN; HALF-LIFE; MOLECULAR STRUCTURE; PHARMACOKINETICS;

EID: 0030265277     PISSN: 02637855     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0263-7855(96)00081-1     Document Type: Article

References (4)

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2. 2 Gálvez, J. Course on application of molecular connectivity in drug design. Seminar in the Institut de Quimica Computacional, Universitat de Girona, Girona, Spain, December 1994
3. 3 Gálvez, J., García-Domenech, R., de Julian-Ortiz, J.V., and Soler, R. Topological approach to drug design. J. Chem. Inf. Comput. Sci. 1995, 35, 272
4. 4 Curt, D. Antioxidants-possible approach to prevention of cardiovascular diseases. Pharmedicum 1996, 4, 15