메뉴 건너뛰기




Volumn 26, Issue 21, 2007, Pages 4501-4513

Phosphorylation of Bem2p and Bem3p may contribute to local activation of Cdc42p at bud emergence

Author keywords

Bud emergence; Cdc28p; Cdc42p; Cell polarity; Cln2p

Indexed keywords

ACTIN; BEM2P PROTEIN; BEM3P PROTEIN; CYCLIN DEPENDENT KINASE 2; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PROTEIN CDC42; UNCLASSIFIED DRUG;

EID: 35649010000     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601873     Document Type: Article
Times cited : (76)

References (46)
  • 1
    • 3042796979 scopus 로고    scopus 로고
    • GAP control: Regulating the regulators of small GTPases
    • Bernards A, Settleman J (2004) GAP control: regulating the regulators of small GTPases. Trends Cell Biol 14: 377-385
    • (2004) Trends Cell Biol , vol.14 , pp. 377-385
    • Bernards, A.1    Settleman, J.2
  • 2
    • 0033200354 scopus 로고    scopus 로고
    • Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p
    • Blondel M, Alepuz PM, Huang LS, Shaham S, Ammerer G, Peter M (1999) Nuclear export of Far1p in response to pheromones requires the export receptor Msn5p/Ste21p. Genes Dev 13: 2284-2300
    • (1999) Genes Dev , vol.13 , pp. 2284-2300
    • Blondel, M.1    Alepuz, P.M.2    Huang, L.S.3    Shaham, S.4    Ammerer, G.5    Peter, M.6
  • 3
    • 0030722725 scopus 로고    scopus 로고
    • G proteins. The arginine finger strikes again
    • Bourne HR (1997) G proteins. The arginine finger strikes again. Nature 389: 673-674
    • (1997) Nature , vol.389 , pp. 673-674
    • Bourne, H.R.1
  • 4
    • 0030715361 scopus 로고    scopus 로고
    • Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast
    • Brown JL, Jaquenoud M, Gulli MP, Chant J, Peter M (1997) Novel Cdc42-binding proteins Gic1 and Gic2 control cell polarity in yeast. Genes Dev 11: 2972-2982
    • (1997) Genes Dev , vol.11 , pp. 2972-2982
    • Brown, J.L.1    Jaquenoud, M.2    Gulli, M.P.3    Chant, J.4    Peter, M.5
  • 6
    • 0032553474 scopus 로고    scopus 로고
    • The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating
    • Butty AC, Pryciak PM, Huang LS, Herskowitz I, Peter M (1998) The role of Far1p in linking the heterotrimeric G protein to polarity establishment proteins during yeast mating. Science 282: 1511-1516
    • (1998) Science , vol.282 , pp. 1511-1516
    • Butty, A.C.1    Pryciak, P.M.2    Huang, L.S.3    Herskowitz, I.4    Peter, M.5
  • 7
    • 0141541745 scopus 로고    scopus 로고
    • The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast
    • Caviston JP, Longtine M, Pringle JR, Bi E (2003) The role of Cdc42p GTPase-activating proteins in assembly of the septin ring in yeast. Mol Biol Cell 14: 4051-4066
    • (2003) Mol Biol Cell , vol.14 , pp. 4051-4066
    • Caviston, J.P.1    Longtine, M.2    Pringle, J.R.3    Bi, E.4
  • 8
    • 0037384105 scopus 로고    scopus 로고
    • Yeasts make their mark
    • Chang F, Peter M (2003) Yeasts make their mark. Nat Cell Biol 5: 294-299
    • (2003) Nat Cell Biol , vol.5 , pp. 294-299
    • Chang, F.1    Peter, M.2
  • 9
    • 0003592758 scopus 로고    scopus 로고
    • Oxford: Oxford University Press
    • Drubin DG (2000) Cell Polarity. Oxford: Oxford University Press
    • (2000) Cell Polarity
    • Drubin, D.G.1
  • 10
    • 0029012079 scopus 로고
    • Ste5p: A meeting place for MAP kinases and their associates
    • Elion EA (1995) Ste5p: a meeting place for MAP kinases and their associates. Trends Cell Biol 5: 322-327
    • (1995) Trends Cell Biol , vol.5 , pp. 322-327
    • Elion, E.A.1
  • 12
    • 0037148528 scopus 로고    scopus 로고
    • Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p
    • Gladfelter AS, Bose I, Zyla TR, Bardes ES, Lew DJ (2002) Septin ring assembly involves cycles of GTP loading and hydrolysis by Cdc42p. J Cell Biol 156: 315-326
    • (2002) J Cell Biol , vol.156 , pp. 315-326
    • Gladfelter, A.S.1    Bose, I.2    Zyla, T.R.3    Bardes, E.S.4    Lew, D.J.5
  • 13
    • 0033635230 scopus 로고    scopus 로고
    • Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast
    • Gulli MP, Jaquenoud M, Shimada Y, Niederhauser G, Wiget P, Peter M (2000) Phosphorylation of the Cdc42 exchange factor Cdc24 by the PAK-like kinase Cla4 may regulate polarized growth in yeast. Mol Cell 6: 1155-1167
    • (2000) Mol Cell , vol.6 , pp. 1155-1167
    • Gulli, M.P.1    Jaquenoud, M.2    Shimada, Y.3    Niederhauser, G.4    Wiget, P.5    Peter, M.6
  • 15
    • 0027437850 scopus 로고
    • Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2
    • Gyuris J, Golemis E, Chertkov H, Brent R (1993) Cdi1, a human G1 and S phase protein phosphatase that associates with Cdk2. Cell 75: 791-803
    • (1993) Cell , vol.75 , pp. 791-803
    • Gyuris, J.1    Golemis, E.2    Chertkov, H.3    Brent, R.4
  • 16
    • 0030693702 scopus 로고    scopus 로고
    • Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast
    • Henchoz S, Chi Y, Catarin B, Herskowitz I, Deshaies RJ, Peter M (1997) Phosphorylation- and ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor Far1p in budding yeast. Genes Dev 11: 3046-3060
    • (1997) Genes Dev , vol.11 , pp. 3046-3060
    • Henchoz, S.1    Chi, Y.2    Catarin, B.3    Herskowitz, I.4    Deshaies, R.J.5    Peter, M.6
  • 18
    • 0033846845 scopus 로고    scopus 로고
    • Gic2p may link activated Cdc42p to components involved in actin polarization, including Bni1p and Bud6p (Aip3p)
    • Jaquenoud M, Peter M (2000) Gic2p may link activated Cdc42p to components involved in actin polarization, including Bni1p and Bud6p (Aip3p). Mol Cell Biol 20: 6244-6258
    • (2000) Mol Cell Biol , vol.20 , pp. 6244-6258
    • Jaquenoud, M.1    Peter, M.2
  • 19
    • 0032530333 scopus 로고    scopus 로고
    • The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex
    • Jaquenoud M, Gulli MP, Peter K, Peter M (1998) The Cdc42p effector Gic2p is targeted for ubiquitin-dependent degradation by the SCFGrr1 complex. EMBO J 17: 5360-5373
    • (1998) EMBO J , vol.17 , pp. 5360-5373
    • Jaquenoud, M.1    Gulli, M.P.2    Peter, K.3    Peter, M.4
  • 20
    • 0033007293 scopus 로고    scopus 로고
    • Cdc42: An essential Rho-type GTPase controlling eukaryotic cell polarity
    • Johnson DI (1999) Cdc42: an essential Rho-type GTPase controlling eukaryotic cell polarity. Microbiol Mol Biol Rev 63: 54-105
    • (1999) Microbiol Mol Biol Rev , vol.63 , pp. 54-105
    • Johnson, D.I.1
  • 21
    • 0035906952 scopus 로고    scopus 로고
    • A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity
    • Kang PJ, Sanson A, Lee B, Park HO (2001) A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity. Science 292: 1376-1378
    • (2001) Science , vol.292 , pp. 1376-1378
    • Kang, P.J.1    Sanson, A.2    Lee, B.3    Park, H.O.4
  • 22
    • 0028073155 scopus 로고
    • Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: Possible role of protein phosphorylation
    • Kim YJ, Francisco L, Chen GC, Marcotte E, Chan CS (1994) Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol 127: 1381-1394
    • (1994) J Cell Biol , vol.127 , pp. 1381-1394
    • Kim, Y.J.1    Francisco, L.2    Chen, G.C.3    Marcotte, E.4    Chan, C.S.5
  • 23
    • 0036219106 scopus 로고    scopus 로고
    • Models of eukaryotic gradient sensing: Application to chemotaxis of amoebae and neutrophils
    • Levchenko A, Iglesias PA (2002) Models of eukaryotic gradient sensing: application to chemotaxis of amoebae and neutrophils. Biophys J 82: 50-63
    • (2002) Biophys J , vol.82 , pp. 50-63
    • Levchenko, A.1    Iglesias, P.A.2
  • 24
  • 26
    • 0037213689 scopus 로고    scopus 로고
    • Rho GTPase-activating proteins in cell regulation
    • Moon SY, Zheng Y (2003) Rho GTPase-activating proteins in cell regulation. Trends Cell Biol 13: 13-22
    • (2003) Trends Cell Biol , vol.13 , pp. 13-22
    • Moon, S.Y.1    Zheng, Y.2
  • 27
    • 0034688998 scopus 로고    scopus 로고
    • Nucleocytoplasmic shuttling of the Cdc42p exchange factor Cdc24p
    • Nern A, Arkowitz RA (2000) Nucleocytoplasmic shuttling of the Cdc42p exchange factor Cdc24p. J Cell Biol 148: 1115-1122
    • (2000) J Cell Biol , vol.148 , pp. 1115-1122
    • Nern, A.1    Arkowitz, R.A.2
  • 28
    • 26444469935 scopus 로고    scopus 로고
    • A system of counteracting feedback loops regulates Cdc42p activity during spontaneous cell polarization
    • Ozbudak EM, Becskei A, van Oudenaarden A (2005) A system of counteracting feedback loops regulates Cdc42p activity during spontaneous cell polarization. Dev Cell 9: 565-571
    • (2005) Dev Cell , vol.9 , pp. 565-571
    • Ozbudak, E.M.1    Becskei, A.2    van Oudenaarden, A.3
  • 29
    • 0026578746 scopus 로고
    • Mitogen-activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34cdc2
    • Peter M, Sanghera JS, Pelech SL, Nigg EA (1992) Mitogen-activated protein kinases phosphorylate nuclear lamins and display sequence specificity overlapping that of mitotic protein kinase p34cdc2. Eur J Biochem 205: 287-294
    • (1992) Eur J Biochem , vol.205 , pp. 287-294
    • Peter, M.1    Sanghera, J.S.2    Pelech, S.L.3    Nigg, E.A.4
  • 30
    • 0028148453 scopus 로고
    • Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast
    • Peterson J, Zheng Y, Bender L, Myers A, Cerione R, Bender A (1994) Interactions between the bud emergence proteins Bem1p and Bem2p and Rho-type GTPases in yeast. J Cell Biol 127: 1395-1406
    • (1994) J Cell Biol , vol.127 , pp. 1395-1406
    • Peterson, J.1    Zheng, Y.2    Bender, L.3    Myers, A.4    Cerione, R.5    Bender, A.6
  • 31
    • 0034002965 scopus 로고    scopus 로고
    • Polarization of cell growth in yeast I: Establishment and maintenance of polarity states
    • Pruyne D, Bretscher A (2000) Polarization of cell growth in yeast I: establishment and maintenance of polarity states. J Cell Sci 113: 365-375
    • (2000) J Cell Sci , vol.113 , pp. 365-375
    • Pruyne, D.1    Bretscher, A.2
  • 32
    • 0030716497 scopus 로고    scopus 로고
    • Structure at 1.65Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue
    • Rittinger K, Walker PA, Eccleston JF, Smerdon SJ, Gamblin SJ (1997) Structure at 1.65Å of RhoA and its GTPase-activating protein in complex with a transition-state analogue. Nature 389: 758-762
    • (1997) Nature , vol.389 , pp. 758-762
    • Rittinger, K.1    Walker, P.A.2    Eccleston, J.F.3    Smerdon, S.J.4    Gamblin, S.J.5
  • 33
    • 0033788675 scopus 로고    scopus 로고
    • Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mating
    • Shimada Y, Gulli MP, Peter M (2000) Nuclear sequestration of the exchange factor Cdc24 by Far1 regulates cell polarity during yeast mating. Nat Cell Biol 2: 117-124
    • (2000) Nat Cell Biol , vol.2 , pp. 117-124
    • Shimada, Y.1    Gulli, M.P.2    Peter, M.3
  • 34
    • 1842472163 scopus 로고    scopus 로고
    • The nucleotide exchange factor Cdc24p may be regulated by autoinhibition
    • Shimada Y, Wiget P, Gulli MP, Bi E, Peter M (2004) The nucleotide exchange factor Cdc24p may be regulated by autoinhibition. EMBO J 23: 1051-1062
    • (2004) EMBO J , vol.23 , pp. 1051-1062
    • Shimada, Y.1    Wiget, P.2    Gulli, M.P.3    Bi, E.4    Peter, M.5
  • 35
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae
    • Sikorski RS, Hieter P (1989) A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 37
    • 1442353156 scopus 로고    scopus 로고
    • Polarizing without a c(l)ue
    • Sohrmann M, Peter M (2003) Polarizing without a c(l)ue. Trends Cell Biol 13: 526-533
    • (2003) Trends Cell Biol , vol.13 , pp. 526-533
    • Sohrmann, M.1    Peter, M.2
  • 38
    • 35649013877 scopus 로고    scopus 로고
    • Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast
    • in press
    • Sopko R, Huang D, Smith JC, Figeys D, Andrews B (2007) Activation of the Cdc42p GTPase by cyclin-dependent protein kinases in budding yeast. EMBO J (in press)
    • (2007) EMBO J
    • Sopko, R.1    Huang, D.2    Smith, J.C.3    Figeys, D.4    Andrews, B.5
  • 39
    • 0033592690 scopus 로고    scopus 로고
    • The guanine-nucleotide-exchange factor cdc24p is targeted to the nucleus and polarized growth sites
    • Toenjes KA, Sawyer MM, Johnson DI (1999) The guanine-nucleotide-exchange factor cdc24p is targeted to the nucleus and polarized growth sites. Curr Biol 9: 1183-1186
    • (1999) Curr Biol , vol.9 , pp. 1183-1186
    • Toenjes, K.A.1    Sawyer, M.M.2    Johnson, D.I.3
  • 41
    • 0035203511 scopus 로고    scopus 로고
    • MAP kinase dynamics in response to pheromones in budding yeast
    • van Drogen F, Stucke VM, Jorritsma G, Peter M (2001) MAP kinase dynamics in response to pheromones in budding yeast. Nat Cell Biol 3: 1051-1059
    • (2001) Nat Cell Biol , vol.3 , pp. 1051-1059
    • van Drogen, F.1    Stucke, V.M.2    Jorritsma, G.3    Peter, M.4
  • 42
    • 0029164907 scopus 로고
    • The rho-GAP encoded by BEM2 regulates cytoskeletal structure in budding yeast
    • Wang T, Bretscher A (1995) The rho-GAP encoded by BEM2 regulates cytoskeletal structure in budding yeast. Mol Biol Cell 6: 1011-1024
    • (1995) Mol Biol Cell , vol.6 , pp. 1011-1024
    • Wang, T.1    Bretscher, A.2
  • 43
    • 0037385661 scopus 로고    scopus 로고
    • Spontaneous cell polarization: Undermining determinism
    • Wedlich-Soldner R, Li R (2003) Spontaneous cell polarization: undermining determinism. Nat Cell Biol 5: 267-270
    • (2003) Nat Cell Biol , vol.5 , pp. 267-270
    • Wedlich-Soldner, R.1    Li, R.2
  • 44
    • 0033613927 scopus 로고    scopus 로고
    • A built-in arginine finger triggers the self-stimulatory GTPase-activating activity of rho family GTPases
    • Zhang B, Zhang Y, Collins CC, Johnson DI, Zheng Y (1999) A built-in arginine finger triggers the self-stimulatory GTPase-activating activity of rho family GTPases. J Biol Chem 274: 2609-2612
    • (1999) J Biol Chem , vol.274 , pp. 2609-2612
    • Zhang, B.1    Zhang, Y.2    Collins, C.C.3    Johnson, D.I.4    Zheng, Y.5
  • 45
    • 0028023358 scopus 로고
    • Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3
    • Zheng Y, Cerione R, Bender A (1994) Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3. J Biol Chem 269: 2369-2372
    • (1994) J Biol Chem , vol.269 , pp. 2369-2372
    • Zheng, Y.1    Cerione, R.2    Bender, A.3
  • 46
    • 0027504343 scopus 로고
    • Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain
    • Zheng Y, Hart MJ, Shinjo K, Evans T, Bender A, Cerione RA (1993) Biochemical comparisons of the Saccharomyces cerevisiae Bem2 and Bem3 proteins. Delineation of a limit Cdc42 GTPase-activating protein domain. J Biol Chem 268: 24629-24634
    • (1993) J Biol Chem , vol.268 , pp. 24629-24634
    • Zheng, Y.1    Hart, M.J.2    Shinjo, K.3    Evans, T.4    Bender, A.5    Cerione, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.