PAR-2 activation increases human intestinal mucin secretion through EGFR transactivation

Biochemical and Biophysical Research Communications

Volumn 364, Issue 3, 2007, Pages 689-694

  Jarry, Anne ^a   Dorso, Laetitia ^a   Gratio, Valérie ^b   Forgue Lafitte, Marie Elisabeth ^a   Laburthe, Marc ^b   Laboisse, Christian L ^a   Darmoul, Dalila ^b  

^a INSERM   (France)

^b CENTRE DE RECHERCHE BIOMÉDICALE BICHAT BEAUJON CRB3   (France)

Author keywords

Calcium; EGFR; Human colonic epithelial cells; MAP kinases; Mucus secretion; Protease activated receptor 2; Trypsin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CALCIUM CHELATING AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; MUCIN; PROTEINASE ACTIVATED RECEPTOR 2; TRYPSIN;

ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; INTESTINE SECRETION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

CALCIUM SIGNALING; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HT29 CELLS; HUMANS; INTESTINAL SECRETIONS; MITOGEN-ACTIVATED PROTEIN KINASES; MUCINS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, PAR-2; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS);

EID: 35649003371     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.073     Document Type: Article

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