Green tea flavonoid epigallocatechin-3-gallate (EGCG) inhibits cardiac hERG potassium channels

Biochemical and Biophysical Research Communications

Volumn 364, Issue 3, 2007, Pages 429-435

  Kelemen, Kamilla ^a   Kiesecker, Claudia ^a   Zitron, Edgar ^a   Bauer, Alexander ^a   Scholz, Eberhard ^a   Bloehs, Ramona ^a   Thomas, Dierk ^a   Greten, Johannes ^a   Remppis, Andrew ^a   Schoels, Wolfgang ^b   Katus, Hugo A ^a   Karle, Christoph A ^a  

^a UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^b Herzzentrum Duisburg   (Germany)

Author keywords

Cardiac repolarization; EGCG; Green tea; hERG; Potassium channel

Indexed keywords

EPIGALLOCATECHIN GALLATE; FLAVONOID; POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT;

ANIMAL CELL; ARTICLE; CELL STRAIN HEK293; CLONING; CONTROLLED STUDY; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; IC 50; NONHUMAN; OOCYTE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; TEA; XENOPUS; XENOPUS LAEVIS;

ANIMALS; CATECHIN; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; ETHER-A-GO-GO POTASSIUM CHANNELS; ION CHANNEL GATING; KIDNEY; OOCYTES; POTASSIUM; TEA; XENOPUS LAEVIS;

XENOPUS LAEVIS;

EID: 35649000334     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.10.001     Document Type: Article

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