Manipulation of intracellular magnesium levels in Saccharomyces cerevisiae with deletion of magnesium transporters

Applied Microbiology and Biotechnology

Volumn 77, Issue 2, 2007, Pages 411-425

  Da Costa, Bernardo M T ^a   Cornish, Katrina ^b   Keasling, Jay D ^a,c,d  

^a University of California   (United States)

^b Yulex Corporation   (United States)

^c University of California   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

Alr1; Alr2; Magnesium; Saccharomyces cerevisiae

Indexed keywords

CELL MEMBRANES; ENZYME ACTIVITY; MAGNESIUM; METAL IONS; MICROORGANISMS;

CELLULAR MECHANISM; MAGNESIUM REGULATION; MAGNESIUM TRANSPORTERS; METAL HOMEOSTASIS;

YEAST;

METAL ION;

CYTOLOGY; HOMEOSTASIS; ION; MAGNESIUM; MEMBRANE; YEAST;

ARABIDOPSIS; ARTICLE; ATOMIC EMISSION SPECTROMETRY; CELL MEMBRANE; ENZYME ACTIVITY; IN VIVO STUDY; NONHUMAN; PLASMID; SACCHAROMYCES CEREVISIAE; WILD TYPE; YEAST;

ARABIDOPSIS; CARRIER PROTEINS; CATION TRANSPORT PROTEINS; CULTURE MEDIA; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; HOMEOSTASIS; MAGNESIUM; PLASMIDS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

ARABIDOPSIS THALIANA; SACCHAROMYCES CEREVISIAE;

EID: 35648967622     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-007-1177-4     Document Type: Article

References (48)

1. Brandt DR, Ross EM (1986) Catecholamine-stimulated GTPase cycle. Multiple sites of regulation by beta-adrenergic receptor and Mg2+ studied in reconstituted receptor-Gs vesicles. J Biol Chem 261:1656-1664
2. Bui DM et al (1999) The bacterial magnesium transporter CorA can functionally substitute for its putative homologue Mrs2p in the yeast inner mitochondrial membrane. J Biol Chem 274:20438-20443
3. Butt TR et al (1984) Copper metallothionein of yeast, structure of the gene, and regulation of expression. A Proc Natl Acad Sci USA 81:3332-3336
4. Cech SY, Maguire ME (1982) Magnesium regulation of the beta-receptor-adenylate cyclase complex.1. Effects of manganese on receptor-binding and cyclase activation. Mol Pharmacol 22:267-273
5. Cech SY et al (1980) Adenylate-cyclase-the role of magnesium and other divalent-cations. Mol Cell Biochem 33:67-92
6. Chamnongpol S, Groisman EA (2002) Mg2+ homeostasis and avoidance of metal toxicity. Mol Microbiol 44:561-571
7. Culotta VC et al (1994) CRS5 encodes a metallothionein-like protein in Saccharomyces cerevisiae. J Biol Chem 269:25295-25302
8. Culotta VC et al (2005) Manganese transport and trafficking: lessons learned from Saccharomyces cerevisiae. Eukaryot Cell 4:1159-1165
9. da Costa BM et al (2005) Regulation of rubber biosynthetic rate and molecular weight in Hevea brasiliensis by metal cofactor. Biomacromolecules 6:279-289
10. da Costa BMT et al (2006) Magnesium ion regulation of in vitro rubber biosynthesis by Parthenium argentatum Gray. Phytochemistry 67:1621-1628
11. Dancis A et al (1994) S. Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell 76:393-402
12. Dennis PB et al (2001) T.O.R. Mammalian, a homeostatic ATP sensor. Science 294:1102-1105
13. Drummond RSM et al (2006) A putative magnesium transporter AtMRS2-11 is localized to the plant chloroplast envelope membrane system. Plant Sci 170:78-89
14. Eide DJ (1998) The molecular biology of metal ion transport in Saccharomyces cerevisiae. Annu Rev Nutr 18:441-469
15. Eide DJ et al (2005) Characterization of the yeast ionome: a genome-wide analysis of nutrient mineral and trace element homeostasis in Saccharomyces cerevisiae. Genome Biol 6:R77
16. Gardner RC (2003) Genes for magnesium transport. Curr Opin Plant Biol 6:263-267
17. Gietz RD, Woods RA (2002) Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method. Guide to Yeast Genetics and Molecular and Cell Biology B Pt 350:87-96
18. Graschopf A et al (2001) The yeast plasma membrane protein Alr1 controls Mg2+ homeostasis and is subject to Mg2+-dependent control of its synthesis and degradation. J Biol Chem 276:16216-16222
19. Gregan J et al (2001) The mitochondrial inner membrane protein Lpe10p, a homologue of Mrs2p, is essential for magnesium homeostasis and group II intron splicing in yeast. Mol Gen Genet 264:773-781
20. Higashijima T et al (1987) Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins. J Biol Chem 262:762-766
21. Horlitz M, Klaff P (2000) Gene-specific trans-regulatory functions of magnesium for chloroplast mRNA stability in higher plants. J Biol Chem 275:35638-35645
22. Karin M et al (1984) Primary structure and transcription of an amplified genetic locus: the CUP1 locus of yeast. A Proc Natl Acad Sci USA 81:337-341
23. Li L, Kaplan J (1998) Defects in the yeast high affinity iron transport system result in increased metal sensitivity because of the increased expression of transporters with a broad transition metal specificity. J Biol Chem 273:22181-22187
24. Li LG et al (2001) A novel family of magnesium transport genes in arabidopsis. Plant Cell 13:2761-2775
25. Liu XF, Culotta VC (1999a) Mutational analysis of Saccharomyces cerevisiae Smf1p, a member of the Nramp family of metal transporters. J Mol Biol 289:885-891
26. Liu XF, Culotta VC (1999b) Post-translation control of Nramp metal transport in yeast. Role of metal ions and the BSD2 gene. J Biol Chem 274:4863-4868
27. Liu GJ et al (2002) Large Mg2+-dependent currents are associated with the increased expression of ALR1 in Saccharomyces cerevisiae. FEMS Microbiol Lett 213:231-237
28. MacDiarmid CW, Gardner RC (1998) Overexpression of the Saccharomyces cerevisiae magnesium transport system confers resistance to aluminum ion. J Biol Chem 273:1727-1732
29. MacDiarmid CW et al (2000) Zinc transporters that regulate vacuolar zinc storage in Saccharomyces cerevisiae. EMBO J 19:2845-2855
30. Maguire ME (1984) Hormone-sensitive magnesium transport and magnesium regulation of adenylate-cyclase. Trends Pharmacol Sci 5:73-77
31. Meijer AH et al (1998) Vectors for transcription factor cloning and target site identification by means of genetic selection in yeast. Yeast 14:1407-1415
32. Moncrief MBC, Maguire ME (1999) Magnesium transport in prokaryotes. J Biol Inorg Chem 4:523-527
33. Montell C (2003) Mg2+ homeostasis: the Mg(2+)nificent TRPM chanzymes. Curr Biol 13:R799-R801
34. Nadler MJS et al (2001) LTRPC7 is a Mg center dot ATP-regulated divalent cation channel required for cell viability. Nature 411:590-595
35. Portnoy ME et al (2000) Saccharomyces cerevisiae expresses three functionally distinct homologues of the nramp family of metal transporters. Mol Cell Biol 20:7893-7902
36. Radisky D, Kaplan J (1999) Regulation of transition metal transport across the yeast plasma membrane. J Biol Chem 274:4481-4484
37. Romani AMP, Maguire ME (2002) Hormonal regulation of Mg2+ transport and homeostasis in eukaryotic cells. Biometals 15:271-283
38. Rubin H (1975) Central role for magnesium in coordinate control of metabolism and growth in animal cells. Proc Natl Acad Sci USA 72:3551-3555
39. Rubin H (2005) Magnesium: the missing element in molecular views of cell proliferation control. Bioessays 27:311-320
40. Sambrook J, Russel DW (2001) Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor
41. Sanui H, Rubin AH (1978) Membrane bound and cellular cationic changes associated with insulin stimulation of cultured cells. J Cell Physiol 96:265-278
42. Schock I et al (2000) A member of a novel Arabidopsis thaliana gene family of candidate Mg2+ ion transporters complements a yeast mitochondrial group II intron-splicing mutant. Plant J 24:489-501
43. Shaul O (2002) Magnesium transport and function in plants: the tip of the iceberg. Biometals 15:309-323
44. Stearman R et al (1998) YIpDCE1-an integrating plasmid for dual constitutive expression in yeast. Gene 212:197-202
45. Wachek M et al (2006) Oligomerization of the Mg2+-transport proteins Alr1p and Alr2p in yeast plasma membrane. FEBS J 273:4236-4249
46. Walker GM, Duffus JH (1980) Magnesium-ions and the control of the cell-cycle in yeast. J Cell Sci 42:329-356
47. Zhao H, Eide D (1996) The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proc Natl Acad Sci USA 93:2454-2458
48. Zsurka G et al (2001) The human mitochondrial Mrs2 protein functionally substitutes for its yeast homologue, a candidate magnesium transporter. Genomics 72:158-168