Cytokines, chemokines and adhesion molecules in TMEV-IDD

Experimental Models of Multiple Sclerosis

Volumn , Issue , 2005, Pages 659-671

  Kim, Byung S ^a   Fuller, Alyson C ^a   Koh, Chang Sung ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Astrocyte; Chemokines; Cytokines; Microglia; Oligodendrocyte; TMEV

Indexed keywords

EID: 35549005646     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/0-387-25518-4_33     Document Type: Chapter

References (37)

1. Dal Canto, M. C., Kim, B.S., Miller, S.D., Melvold, R.W. 1996. Theiler's murine encephalomyelitis virus (TMEV)-induced demyelination: A model for human multiple clerosis. Methods 10:453.
2. Kim, B. S., M. A. Lyman, B. S. Kang, H. K. Kang, H. G. Lee, M. Mohindru, and J. P. Palma. 2001. Pathogenesis of virus-induced Immune-mediated demyelination. Immunol Res 24:121.
3. Miller, S. D., Vanderlugt, C. L., Begolka, W. S., Pao, W., Yauch, R. L., Neville, K. L., Katz-Levy, Y., Carrizosa, A., Kim, B. S. 1997. Persistent infection with Theiler's virus leads to CNS autoImmunity via epitope spreading. Nat. Med. 3:1133.
4. Lyman, M. A., H. G. Lee, B. S. Kang, H. K. Kang, and B. S. Kim. 2002. Capsidspecific cytotoxic T lymphocytes recognize three distinct H-2D(b)-restricted regions of the BeAn strain of Theiler's virus and exhibit different cytokine profiles. J Virol 76:3125.
5. Kang, B. S., M. A. Lyman, and B. S. Kim. 2002. The majority of infiltrating CD8+ T cells in the central nervous system of susceptible SJL/J mice infected with Theiler's virus are virus specific and fully functional. J. Virol 76:6577.
6. Yauch, R. L., and B. S. Kim. 1994. A predominant viral epitope recognized by T cells from the periphery and demyelinating lesions of SJL/J mice infected with Theiler's virus is located within VP1(233-244). J. Immunol. 153:4508.
7. Yauch, R. Y., J. P. Palma, H. Yahikozawa, C.-S. Koh, and B. S. Kim. 1998. Role of individual T cell epitopes of Theiler's virus in the pathogenesis of demyelination correlates with the ability to induce a Thl response. J. Virol. 72:6169.
8. Begolka, W. S., C. L. Vanderlugt, S. M. Rahbe, and S. D. Miller. 1998. Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis. J Immunol 161:4437.
9. Sato, S., S. L. Reiner, M. A. Jensen, and R. P. Roos. 1997. Central nervous system cytokine mRNA expression following Theiler's murine encephalomyelitis virus infection. J NeuroImmunol 76:213.
10. Palma, J. P., S. H. Park, and B. S. Kim. 1996. Treatment with lipopolysaccharide enhances the pathogenicity of a low-pathogenic variant of Theiler's murine encephalomyelitis virus. Journal of Neuroscience Research 45:776.
11. Chang, J. R., E. Zaczynska, C. D. Katsetos, C. D. Platsoucas, and E. L. Oleszak. 2000. Differential expression of TGF-beta, IL-2, and other cytokines in the CNS of Theiler's murine encephalomyelitis virus-infected susceptible and resistant strains of mice. Virology 278:346.
12. Sierra, A., and N. Rubio. 1993. Theiler's murine encephalomyelitis virus induces tumour necrosis factor-alpha in murine astrocyte cell cultures. Immunology 78:399.
13. Palma, J. P., R. L. Yauch, H. K. Kang, H. G. Lee, and B. S. Kim. 2002. Preferential induction of IL-10 in APC correlates with a switch from Thl to Th2 response following infection with a low pathogenic variant of Theiler's virus. J Immunol 168:4221.
14. Olson, J. K., A. M. Girvin, and S. D. Miller. 2001. Direct activation of innate and antigen-presenting functions of microglia following infection with Theiler's virus. J Virol 75:9780.
15. Kim, B. S., J. P. Palma, A. Inoue, and C. S. Koh. 2000. Pathogenic Immunity in Theiler's virus-induced demyelinating disease: A viral model for multiple sclerosis. Arch. Immunol. Ther. Exp. 48:373.
16. Inoue, A., C. S. Koh, M. Yamazaki, H. Yahikozawa, M. Ichikawa, H. Yagita, and B. S. Kim. 1998. Suppressive effect on Theiler's murine encephalomyelitis virusinduced demyelinating disease by the administration of anti-lL-12 antibody. J Immunol 161:5586.
17. Bright, J. J., M. Rodriguez, and S. Sriram. 1999. Differential influence of interleukin-12 in the pathogenesis of autoImmune and virus-induced central nervous system demyelination. J Virol 73:1637.
18. Pullen, L. C., S. D. Miller, M. C. Dal Canto, P. H. Van der Meide, and B. S. Kim. 1994. Alteration in the level of interferon-gamma results in acceleration of Theiler's virus-induced demyelinating disease. Journal of NeuroImmunology 55:143.
19. Fiette, L., C. Aubert, U. Muller, S. Huang, M. Aguet, M. Brahic, and J. F. Bureau. 1995. Theiler's virus infection of 129Sv mice that lack the interferon alpha/beta or interferon gamma receptors. Journal of Experimental Medicine 181:2069.
20. Rodriguez, M., K. Pavelko, and R. L. Coffman. 1995. Gamma interferon is critical for resistance to Theiler's virus-induced demyelination. Journal of Virology 69:7286.
21. Inoue, A., C. S. Koh, H. Yahikozawa, N. Yanagisawa, H. Yagita, Y. Ishihara, and B. S. Kim. 1996. The level of tumor necrosis factor-alpha producing cells in the spinal cord correlates with the degree of Theiler's murine encephalomyelitis virusinduced demyelinating disease. International Immunology 8:1001.
22. Paya, C. V., P. J. Leibson, A. K. Patick, and M. Rodriguez. 1990. Inhibition of Theiler's virus-induced demyelination in vivo by tumor necrosis factor alpha. Int Immunol 2:909.
23. Hoffman, L. M., B. T. Fife, W. S. Begolka, S. D. Miller, and W. J. Karpus. 1999. Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease. J Neurovirol 5:635.
24. Murray, P. D., K. Krivacic, A. Chernosky, T. Wei, R. M. Ransohoff, and M. Rodriguez. 2000. Biphasic and regionally-restricted chemokine expression in the central nervous system in the Theiler's virus model of multiple sclerosis [In Process Citation]. J Neurovirol 6 Suppl 1:S44.
25. Ransohoff, R. M., T. Wei, K. D. Pavelko, J. C. Lee, P. D. Murray, and M. Rodriguez. 2002. Chemokine expression in the central nervous system of mice with a viral disease resembling multiple sclerosis: roles of CD4+ and CD8+ T cells and viral persistence. J Virol 76:2217.
26. Theil, D. J., I. Tsunoda, J. E. Libbey, T. J. Derfuss, and R. S. Fujinami. 2000. Alterations in cytokine but not chemokine mRNA expression during three distinct Theiler's virus infections. J NeuroImmunol 104:22.
27. Palma, J. P., and B. S. Kim. 2001. Induction of selected chemokines in glial cells infected with Theiler's virus. J NeuroImmunol 117:166.
28. Lane, T. E., M. T. Liu, B. P. Chen, V. C. Asensio, R. M. Samawi, A. D. Paoletti, I. L. Campbell, S. L. Kunkel, H. S. Fox, and M. J. Buchmeier. 2000. A central role for CD4(+) T cells and RANTES in virus-induced central nervous system inflammation and demyelination. J Virol 74:1415.
29. Liu, M. T., H. S. Keirstead, and T. E. Lane. 2001. Neutralization of the chemokine CXCL10 reduces inflammatory cell invasion and demyelination and improves neurological function in a viral model of multiple sclerosis. J Immunol 167:4091.
30. Inoue, A., C. S. Koh, M. Yamazaki, M. Ichikawa, M. Isobe, Y. Ishihara, H. Yagita, and B. S. Kim. 1997. Anti-adhesion molecule therapy in Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int Immunol 9:1837.
31. Rose, J. W., C. T. Welsh, K. E. Hill, M. K. Houtchens, R. S. Fujinami, and J. J. Townsend. 1999. Contrasting effects of anti-adhesion molecule therapy in experimental allergic encephalomyelitis and Theiler's murine encephalomyelitis. J NeuroImmunol 97:110.
32. Kang, J. A., M. Mohindru, B. S. Kang, S. H. Park, and B. S. Kim. 2000. Clonal expansion of infiltrating T cells in the spinal cords of SJL/J mice infected with Theiler's virus. J Immunol 165:583.
33. Inoue, A., C. S. Koh, M. Yamazaki, and H. Yagita. 1999. Effect of Anti-B7-1 and Anti-B7-2 mAb on Theiler's Murine Encephalomyelitis Virus-Induced Demyelinating Disease. J Immunol 163:6180.
34. Neville, K. L., M. C. Dal Canto, J. A. Bluestone, and S. D. Miller. 2000. CD28 costimulatory blockade exacerbates disease severity and accelerates epitope spreading in a virus-induced autoImmune disease. J Virol 74:8349.
35. Girvin, A. M., K. B. Gordon, C. J. Welsh, N. A. Clipstone, and S. D. Miller. 2002. Differential abilities of central nervous system resident endothelial cells and astrocytes to serve as inducible antigen-presenting cells. Blood 99:3692.
36. Palma, J. P., R. L. Yauch, S. Lang, and B. S. Kim. 1999. Potential role of CD4+ T cell-mediated apoptosis of activated astrocytes in Theiler's virus-induced demyelination. J Immunol 162:6543.
37. Qi, Y., and M. C. Dal Canto. 1996. Effect of Theiler's murine encephalomyelitis virus and cytokines on cultured oligodendrocytes and astrocytes. J Neurosci Res 45:364.