메뉴 건너뛰기




Volumn 23, Issue 7, 2007, Pages 559-566

Reduced NO synthesis and eNOS mRNA expression in endothelial cells from newborns with a strong family history of type 2 diabetes

Author keywords

Endothelium; Glucose; Nitric oxide; Nitric oxide synthase; Reaction oxygen species; Type 2 diabetes mellitus

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE; GLUCOSE TRANSPORTER 1; MESSENGER RNA; NITRIC OXIDE SYNTHASE; PROTEIN P53;

EID: 35548936491     PISSN: 15207552     EISSN: 15207560     Source Type: Journal    
DOI: 10.1002/dmrr.743     Document Type: Article
Times cited : (30)

References (43)
  • 1
    • 0842328975 scopus 로고    scopus 로고
    • Reduced skeletal muscle oxygen uptake and reduced beta-cell function: Two early abnormalities in normal glucose-tolerant offspring of patients with type 2 diabetes
    • Thamer C, Stumvoll M, Niess A, et al. Reduced skeletal muscle oxygen uptake and reduced beta-cell function: two early abnormalities in normal glucose-tolerant offspring of patients with type 2 diabetes. Diabetes Care 2003; 26: 2126-2132.
    • (2003) Diabetes Care , vol.26 , pp. 2126-2132
    • Thamer, C.1    Stumvoll, M.2    Niess, A.3
  • 2
    • 0032878326 scopus 로고    scopus 로고
    • Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes
    • Caballero AE, Arora S, Saouaf R, et al. Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes. Diabetes 1999; 48: 1856-1862.
    • (1999) Diabetes , vol.48 , pp. 1856-1862
    • Caballero, A.E.1    Arora, S.2    Saouaf, R.3
  • 3
    • 33744998335 scopus 로고    scopus 로고
    • Family history of diabetes is a major determinant of endothelial function
    • Goldfine AB, Beckman JA, Betensky RA, et al. Family history of diabetes is a major determinant of endothelial function. J Am Coll Cardiol 2006; 47: 2456-2461.
    • (2006) J Am Coll Cardiol , vol.47 , pp. 2456-2461
    • Goldfine, A.B.1    Beckman, J.A.2    Betensky, R.A.3
  • 4
    • 33749992927 scopus 로고    scopus 로고
    • Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease
    • Reynolds SS, Yanek LR, Vaidya D, et al. Glucose levels in the normal range predict incident diabetes in families with premature coronary heart disease. Diabetes Res Clin Pract 2006; 74: 267-273.
    • (2006) Diabetes Res Clin Pract , vol.74 , pp. 267-273
    • Reynolds, S.S.1    Yanek, L.R.2    Vaidya, D.3
  • 6
    • 17744362283 scopus 로고    scopus 로고
    • Alterations in nitric oxide/cyclic-GMP pathway in nondiabetic siblings of patients with type 2 diabetes
    • Piatti PM, Monti LD, Zavaroni I, et al. Alterations in nitric oxide/cyclic-GMP pathway in nondiabetic siblings of patients with type 2 diabetes. J Clin Endocrinol Metab 2000; 85: 2416-2420.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 2416-2420
    • Piatti, P.M.1    Monti, L.D.2    Zavaroni, I.3
  • 7
    • 0036515166 scopus 로고    scopus 로고
    • Abnormal carbohydrate metabolism during pregnancy: Association with endothelial dysfunction
    • Paradisi G, Biaggi A, Ferrazzani S, De Carolis S, Caruso A. Abnormal carbohydrate metabolism during pregnancy: association with endothelial dysfunction. Diabetes Care 2002; 25: 560-564.
    • (2002) Diabetes Care , vol.25 , pp. 560-564
    • Paradisi, G.1    Biaggi, A.2    Ferrazzani, S.3    De Carolis, S.4    Caruso, A.5
  • 8
    • 0028564839 scopus 로고
    • Human endothelial cells are defective in diabetic vascular disease
    • Sank A, Wei D, Reid J, et al. Human endothelial cells are defective in diabetic vascular disease. J Surg Res 1994; 57: 647-653.
    • (1994) J Surg Res , vol.57 , pp. 647-653
    • Sank, A.1    Wei, D.2    Reid, J.3
  • 9
    • 0029784821 scopus 로고    scopus 로고
    • Activation of endothelial cells during insulin-dependent diabetes mellitus: A biochemical and morphological study
    • Cester N, Rabini RA, Salvolini E, et al. Activation of endothelial cells during insulin-dependent diabetes mellitus: a biochemical and morphological study. Eur J Clin Invest 1996; 26: 569-573.
    • (1996) Eur J Clin Invest , vol.26 , pp. 569-573
    • Cester, N.1    Rabini, R.A.2    Salvolini, E.3
  • 10
    • 3543067677 scopus 로고    scopus 로고
    • GLUT1-deficient mice exhibit impaired endothelium-dependent vascular relaxation
    • Park JL, Heilig CW, Brosius FC III. GLUT1-deficient mice exhibit impaired endothelium-dependent vascular relaxation. Eur J Pharmacol 2004; 496: 213-214.
    • (2004) Eur J Pharmacol , vol.496 , pp. 213-214
    • Park, J.L.1    Heilig, C.W.2    Brosius III, F.C.3
  • 12
    • 33645224640 scopus 로고    scopus 로고
    • p53 Mediates the accelerated onset of senescence of endothelial progenitor cells in diabetes
    • Rosso A, Balsamo A, Gambino R, et al. p53 Mediates the accelerated onset of senescence of endothelial progenitor cells in diabetes. J Biol Chem 2006; 281: 4339-4347.
    • (2006) J Biol Chem , vol.281 , pp. 4339-4347
    • Rosso, A.1    Balsamo, A.2    Gambino, R.3
  • 13
    • 0346025543 scopus 로고    scopus 로고
    • Amadori-configurated albumin induces nitric oxide-dependent apoptosis of endothelial cells: A possible mechanism of diabetic vasculopathy
    • Amore A, Cirina P, Conti G, et al. Amadori-configurated albumin induces nitric oxide-dependent apoptosis of endothelial cells: a possible mechanism of diabetic vasculopathy. Nephrol Dial Transplant 2004; 19: 53-60.
    • (2004) Nephrol Dial Transplant , vol.19 , pp. 53-60
    • Amore, A.1    Cirina, P.2    Conti, G.3
  • 14
    • 33745149291 scopus 로고    scopus 로고
    • p53 regulates mitochondrial respiration
    • Matoba S, Kang JG, Patino WD, et al. p53 regulates mitochondrial respiration. Science 2006; 312: 1650-1653.
    • (2006) Science , vol.312 , pp. 1650-1653
    • Matoba, S.1    Kang, J.G.2    Patino, W.D.3
  • 15
    • 33846553107 scopus 로고    scopus 로고
    • HUVECs from newborns with a strong family history of diabetes show diminished ROS synthesis in the presence of high glucose concentrations
    • Alvarado-Vasquez N, Paez A, Zapata E, et al. HUVECs from newborns with a strong family history of diabetes show diminished ROS synthesis in the presence of high glucose concentrations. Diabetes Metab Res Rev 2007; 23: 71-80.
    • (2007) Diabetes Metab Res Rev , vol.23 , pp. 71-80
    • Alvarado-Vasquez, N.1    Paez, A.2    Zapata, E.3
  • 16
    • 0142227752 scopus 로고    scopus 로고
    • Different growth conditions for peripheral blood endothelial progenitors
    • Di Stefano R, Santoni T, Barsotti MC, et al. Different growth conditions for peripheral blood endothelial progenitors. Cardiovasc Radiat Med 2002; 3:172-175.
    • (2002) Cardiovasc Radiat Med , vol.3 , pp. 172-175
    • Di Stefano, R.1    Santoni, T.2    Barsotti, M.C.3
  • 17
    • 33747423701 scopus 로고    scopus 로고
    • An endothelial-cell-enriched primary culture system to study vascular endothelial growth factor (VEGF A) expression in a teleost, the Japanese eel (Anguilla japonica)
    • Huang YS, Huang WL, Lin WF, Chen MC, Jeng SR. An endothelial-cell-enriched primary culture system to study vascular endothelial growth factor (VEGF A) expression in a teleost, the Japanese eel (Anguilla japonica). Comp Biochem Physiol A Mol Integr Physiol 2006; 145: 33-46.
    • (2006) Comp Biochem Physiol A Mol Integr Physiol , vol.145 , pp. 33-46
    • Huang, Y.S.1    Huang, W.L.2    Lin, W.F.3    Chen, M.C.4    Jeng, S.R.5
  • 18
    • 0026677279 scopus 로고
    • Effects of high glucose concentration on survival and respiration of human endothelial cells
    • Foultier MT, Vonarx-Coinsmann V, Patrice T, Cloarec D, Xu XN, Combre A. Effects of high glucose concentration on survival and respiration of human endothelial cells. Biochimie 1992; 74: 975-979.
    • (1992) Biochimie , vol.74 , pp. 975-979
    • Foultier, M.T.1    Vonarx-Coinsmann, V.2    Patrice, T.3    Cloarec, D.4    Xu, X.N.5    Combre, A.6
  • 19
    • 27144476526 scopus 로고    scopus 로고
    • DAF-FM [4-amino-5-methylamino-2′,7′-difluorofluorescein] diacetate detects impairment of agonist-stimulated nitric oxide synthesis by elevated glucose in human vascular endothelial cells: Reversal by vitamin C and L-sepiapterin
    • Sheng JZ, Wang D, Braun AP. DAF-FM [4-amino-5-methylamino-2′,7′-difluorofluorescein] diacetate detects impairment of agonist-stimulated nitric oxide synthesis by elevated glucose in human vascular endothelial cells: reversal by vitamin C and L-sepiapterin. J Pharmacol Exp Ther 2005; 315: 931-940.
    • (2005) J Pharmacol Exp Ther , vol.315 , pp. 931-940
    • Sheng, J.Z.1    Wang, D.2    Braun, A.P.3
  • 20
    • 4444283872 scopus 로고    scopus 로고
    • Expresión of Inducible Nitric Oxide Synthase is Increased in Patients with Heart Failure due to Ischemic Disease
    • Ferreiro CR, Chagas ACP, Carvalho MHC, et al. Expresión of Inducible Nitric Oxide Synthase is Increased in Patients with Heart Failure due to Ischemic Disease. Braz J Med Biol Res 2004; 37: 1313-1320.
    • (2004) Braz J Med Biol Res , vol.37 , pp. 1313-1320
    • Ferreiro, C.R.1    Chagas, A.C.P.2    Carvalho, M.H.C.3
  • 21
    • 0034241451 scopus 로고    scopus 로고
    • Glucose Transporter 1 [GLUT1] Expression is Associated with Intestinal Type of Gastric Carcinoma
    • Kim WS, Kim YY, Jang SJ, Kimm K, Jung MH. Glucose Transporter 1 [GLUT1] Expression is Associated with Intestinal Type of Gastric Carcinoma. J Korean Med Sci 2000; 15:420-424.
    • (2000) J Korean Med Sci , vol.15 , pp. 420-424
    • Kim, W.S.1    Kim, Y.Y.2    Jang, S.J.3    Kimm, K.4    Jung, M.H.5
  • 22
    • 0034681949 scopus 로고    scopus 로고
    • Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjectswith type 2 diabetes in association with insulin resistance
    • Balletshofer BM, Rittig K, Enderle MD, et al. Endothelial dysfunction is detectable in young normotensive first-degree relatives of subjectswith type 2 diabetes in association with insulin resistance. Circulation 2000; 101: 1780-1784.
    • (2000) Circulation , vol.101 , pp. 1780-1784
    • Balletshofer, B.M.1    Rittig, K.2    Enderle, M.D.3
  • 23
    • 0033231839 scopus 로고    scopus 로고
    • Nitric oxide prevents apoptosis of human endothelial cells from high glucose exposure during early stage
    • Ho FM, Liu SH, Liau CS, Huang PJ, Shiah SG, Lin-Shiau SY. Nitric oxide prevents apoptosis of human endothelial cells from high glucose exposure during early stage. J Cell Biochem 1999; 75: 258-263.
    • (1999) J Cell Biochem , vol.75 , pp. 258-263
    • Ho, F.M.1    Liu, S.H.2    Liau, C.S.3    Huang, P.J.4    Shiah, S.G.5    Lin-Shiau, S.Y.6
  • 24
    • 27844593740 scopus 로고    scopus 로고
    • High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway
    • Ho FM, Lin WW, Chen BC, et al. High glucose-induced apoptosis in human vascular endothelial cells is mediated through NF-kappaB and c-Jun NH2-terminal kinase pathway and prevented by PI3K/Akt/eNOS pathway. Cell Signal 2006; 18: 391-399.
    • (2006) Cell Signal , vol.18 , pp. 391-399
    • Ho, F.M.1    Lin, W.W.2    Chen, B.C.3
  • 25
    • 11144262141 scopus 로고    scopus 로고
    • Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells
    • Srinivasan S, Hatley ME, Bolick DT, et al. Hyperglycaemia-induced superoxide production decreases eNOS expression via AP-1 activation in aortic endothelial cells. Diabetologia 2004; 47: 1727-1734.
    • (2004) Diabetologia , vol.47 , pp. 1727-1734
    • Srinivasan, S.1    Hatley, M.E.2    Bolick, D.T.3
  • 26
    • 21644489785 scopus 로고    scopus 로고
    • Up-regulation of the association between heat shock protein 90 and endothelial nitric oxide synthase prevents high glucose-induced apoptosis in human endothelial cells
    • Lin LY, Lin CY, Ho FM, Liau CS. Up-regulation of the association between heat shock protein 90 and endothelial nitric oxide synthase prevents high glucose-induced apoptosis in human endothelial cells. J Cell Biochem 2005; 94: 194-201.
    • (2005) J Cell Biochem , vol.94 , pp. 194-201
    • Lin, L.Y.1    Lin, C.Y.2    Ho, F.M.3    Liau, C.S.4
  • 27
    • 33645870995 scopus 로고    scopus 로고
    • High glucose-mediated imbalance of nitric oxide synthase and dimethylarginine dimethylaminohydrolase expression in endothelial cells
    • Sorrenti V, Mazza F, Campisi A, Vanella L, Li Volti G, Di Giacomo C. High glucose-mediated imbalance of nitric oxide synthase and dimethylarginine dimethylaminohydrolase expression in endothelial cells. Curr Neurovasc Res 2006; 3: 49-54.
    • (2006) Curr Neurovasc Res , vol.3 , pp. 49-54
    • Sorrenti, V.1    Mazza, F.2    Campisi, A.3    Vanella, L.4    Li Volti, G.5    Di Giacomo, C.6
  • 28
    • 0027202456 scopus 로고
    • Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease
    • Dinerman JL, Lowenstein CJ, Snyder SH. Molecular mechanisms of nitric oxide regulation. Potential relevance to cardiovascular disease. Circ Res 1993; 73: 217-222.
    • (1993) Circ Res , vol.73 , pp. 217-222
    • Dinerman, J.L.1    Lowenstein, C.J.2    Snyder, S.H.3
  • 30
    • 33846392950 scopus 로고    scopus 로고
    • Regulation of endothelial and myocardialNO synthesis by multi-site eNOS phosphorylation
    • Mount PF, Kemp BE, Power DA. Regulation of endothelial and myocardialNO synthesis by multi-site eNOS phosphorylation. J Mol Cell Cardiol 2007; 42: 271-279.
    • (2007) J Mol Cell Cardiol , vol.42 , pp. 271-279
    • Mount, P.F.1    Kemp, B.E.2    Power, D.A.3
  • 31
    • 24044517938 scopus 로고    scopus 로고
    • Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease
    • Sasso FC, Torella D, Carbonara O, et al. Increased vascular endothelial growth factor expression but impaired vascular endothelial growth factor receptor signaling in the myocardium of type 2 diabetic patients with chronic coronary heart disease. J Am Coll Cardiol 2005; 46: 827-834.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 827-834
    • Sasso, F.C.1    Torella, D.2    Carbonara, O.3
  • 33
    • 5444245184 scopus 로고    scopus 로고
    • Effect of extracellular hypertonicity and alkalosis on endothelial-derived EA.hy 926 cells in vitro
    • Hirsch C, Haller C. Effect of extracellular hypertonicity and alkalosis on endothelial-derived EA.hy 926 cells in vitro. Eur J Med Res 2004; 9: 71-77.
    • (2004) Eur J Med Res , vol.9 , pp. 71-77
    • Hirsch, C.1    Haller, C.2
  • 34
    • 0031785280 scopus 로고    scopus 로고
    • Mannitol at clinical concentrations activates multiple signaling pathways and induces apoptosis in endothelial cells
    • Malek AM, Goss GG, Jiang L, Izumo S, Alper SL. Mannitol at clinical concentrations activates multiple signaling pathways and induces apoptosis in endothelial cells. Stroke 1998; 29: 2631-2640.
    • (1998) Stroke , vol.29 , pp. 2631-2640
    • Malek, A.M.1    Goss, G.G.2    Jiang, L.3    Izumo, S.4    Alper, S.L.5
  • 35
    • 33746122961 scopus 로고    scopus 로고
    • Electron microscopic analysis of glucose-induced endothelial damage in primary culture: Possible mechanism and prevention
    • Mandal AK, Ping T, Caldwell SJ, Bagnell R, Hiebert LM. Electron microscopic analysis of glucose-induced endothelial damage in primary culture: possible mechanism and prevention. Histol Histopathol 2006; 21: 941-950.
    • (2006) Histol Histopathol , vol.21 , pp. 941-950
    • Mandal, A.K.1    Ping, T.2    Caldwell, S.J.3    Bagnell, R.4    Hiebert, L.M.5
  • 36
    • 0037207473 scopus 로고    scopus 로고
    • Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells
    • Mann GE, Yudlevich DL, Sobrevia L. Regulation of amino acid and glucose transporters in endothelial and smooth muscle cells. Physiol Rev 2003; 83: 183-252.
    • (2003) Physiol Rev , vol.83 , pp. 183-252
    • Mann, G.E.1    Yudlevich, D.L.2    Sobrevia, L.3
  • 37
    • 0030895232 scopus 로고    scopus 로고
    • Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects
    • Miele C, Formisano P, Condorelli G, et al. Abnormal glucose transport and GLUT1 cell-surface content in fibroblasts and skeletal muscle from NIDDM and obese subjects. Diabetologia 1997; 40: 421-429.
    • (1997) Diabetologia , vol.40 , pp. 421-429
    • Miele, C.1    Formisano, P.2    Condorelli, G.3
  • 38
    • 10244227968 scopus 로고    scopus 로고
    • Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 [non-insulin-dependent] diabetes mellitus in different populations
    • Pontiroli AE, Capra F, Veglia F, et al. Genetic contribution of polymorphism of the GLUT1 and GLUT4 genes to the susceptibility to type 2 [non-insulin-dependent] diabetes mellitus in different populations. Acta Diabetol 1996; 33: 193-197.
    • (1996) Acta Diabetol , vol.33 , pp. 193-197
    • Pontiroli, A.E.1    Capra, F.2    Veglia, F.3
  • 39
    • 1942506067 scopus 로고    scopus 로고
    • The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression
    • Schwartzenberg-Bar-Yoseph F, Armoni M, Karnieli E. The tumor suppressor p53 down-regulates glucose transporters GLUT1 and GLUT4 gene expression. Cancer Res 2004; 64: 2627-2633.
    • (2004) Cancer Res , vol.64 , pp. 2627-2633
    • Schwartzenberg-Bar-Yoseph, F.1    Armoni, M.2    Karnieli, E.3
  • 40
    • 29344455480 scopus 로고    scopus 로고
    • Advances in understanding the molecular causes of diabetes-induced birth defects
    • Loeken MR. Advances in understanding the molecular causes of diabetes-induced birth defects. J Soc Gynecol Investig 2006; 13: 2-10.
    • (2006) J Soc Gynecol Investig , vol.13 , pp. 2-10
    • Loeken, M.R.1
  • 41
    • 19944428439 scopus 로고    scopus 로고
    • Induction of glucose transporter 1 expression through hypoxia-inducible factor 1alpha under hypoxic conditions in trophoblast-derived cells
    • Hayashi M, Sakata M, Takeda T, et al. Induction of glucose transporter 1 expression through hypoxia-inducible factor 1alpha under hypoxic conditions in trophoblast-derived cells. J Endocrinol 2004; 183: 145-154.
    • (2004) J Endocrinol , vol.183 , pp. 145-154
    • Hayashi, M.1    Sakata, M.2    Takeda, T.3
  • 42
    • 9144273505 scopus 로고    scopus 로고
    • Gene expression in humans with diabetes and prediabetes: What have we learned about diabetes pathophysiology?
    • Patti ME. Gene expression in humans with diabetes and prediabetes: what have we learned about diabetes pathophysiology? Curr Opin Clin Nutr Metab Care 2004; 7: 383-390.
    • (2004) Curr Opin Clin Nutr Metab Care , vol.7 , pp. 383-390
    • Patti, M.E.1
  • 43
    • 3142547390 scopus 로고    scopus 로고
    • Gene expression in the pathophysiology of type 2 diabetes mellitus
    • Patti ME. Gene expression in the pathophysiology of type 2 diabetes mellitus. Curr Diab Rep 2004; 4: 176-181.
    • (2004) Curr Diab Rep , vol.4 , pp. 176-181
    • Patti, M.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.