Sensitivity of the erythrocyte micronucleus assay: Dependence on number of cells scored and inter-animal variability

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 634, Issue 1-2, 2007, Pages 235-240

  Kissling, Grace E ^a   Dertinger, Stephen D ^b   Hayashi, Makoto ^c   MacGregor, James T ^d  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b LITRON LABORATORIES   (United States)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d Toxicology Consulting Services   (United States)

Author keywords

Binomial counting error; Erythrocyte micronucleus assay; Flow cytometry; Inter animal variability; Power calculation

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; CELL COUNT; COMPARATIVE STUDY; CONTROLLED STUDY; DOG; ERYTHROCYTE; FLOW CYTOMETRY; GENETIC VARIABILITY; GENOTOXICITY; MICRONUCLEUS TEST; MICROSCOPY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RAT; RETICULOCYTE; SENSITIVITY ANALYSIS;

ANIMALS; CELL COUNT; DOGS; FLOW CYTOMETRY; MICE; MICRONUCLEUS TESTS; MUTAGENS; RATS; RETICULOCYTES; SENSITIVITY AND SPECIFICITY;

ANIMALIA; CANIS FAMILIARIS; MUS; RATTUS;

EID: 35448979799     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2007.07.010     Document Type: Article

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