MK-801 upregulates NR2A protein levels and induces functional recovery of the ipsilateral hemidiaphragm following acute C2 hemisection in adult rats

Journal of Spinal Cord Medicine

Volumn 30, Issue 4, 2007, Pages 346-354

  Alilain, Warren J ^a,b   Goshgarian, Harry G ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

C2 hemisection; Long term potentiation; MK 801; Motor recovery; N methyl D aspartate (NMDA); NMDA receptor antagonist; Phrenic nucleus; Plasticity; Spinal cord injuries

Indexed keywords

AMPA RECEPTOR; DIZOCILPINE; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; DIZOCILPINE MALEATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NEUROPROTECTIVE AGENT; NR2A NMDA RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CERVICAL SPINAL CORD INJURY; CONTROLLED STUDY; DIAPHRAGM PARALYSIS; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; ELECTROMYOGRAPHY; HEMIDIAPHRAGM; MOTOR PERFORMANCE; NONHUMAN; PHRENIC NERVE; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SINGLE DRUG DOSE; SPINAL CORD HEMISECTION; UPREGULATION; ANALYSIS OF VARIANCE; ANIMAL; CONVALESCENCE; DIAPHRAGM; DRUG EFFECT; FEMALE; HEMISPHERIC DOMINANCE; INNERVATION; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SPINAL CORD INJURY; SPRAGUE DAWLEY RAT; TIME;

ANALYSIS OF VARIANCE; ANIMALS; DIAPHRAGM; DIZOCILPINE MALEATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROMYOGRAPHY; FEMALE; FUNCTIONAL LATERALITY; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; TIME FACTORS; UP-REGULATION;

EID: 35448957243     PISSN: 10790268     EISSN: None     Source Type: Journal    
DOI: 10.1080/10790268.2007.11753950     Document Type: Article

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