Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity

Journal of Neuroscience

Volumn 27, Issue 42, 2007, Pages 11179-11191

  Hefferan, Michael P ^a   Kucharova, Karolina ^a,d   Kinjo, Kiyohiko ^a   Kakinohana, Osamu ^a   Sekerkova, Gabriella ^b   Nakamura, Seiya ^a,c   Fuchigami, Tatsuya ^a,c   Tomori, Zoltan ^e   Yaksh, Tony L ^a   Kurtz, Neil ^f   Marsala, Martin ^a,d  

^a University of California   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c UNIVERSITY OF THE RYUKYUS   (Japan)

^d INSTITUTE OF CHEMISTRY   (Slovakia)

^e INSTITUTE OF EXPERIMENTAL PHYSICS   (Slovakia)

^f TorreyPines Therapeutics Inc   (United States)

Author keywords

AMPA receptor; Astrocytes; Ischemia; Rigidity; Spasticity; Spinal cord injury

Indexed keywords

AMPA RECEPTOR; AMPA RECEPTOR ANTAGONIST; ANTISENSE OLIGODEOXYNUCLEOTIDE; GLUTAMATE RECEPTOR 1; GLUTAMATE RECEPTOR 2; GLUTAMATE RECEPTOR 4; NGX 424; TEZAMPANEL; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECT; ELECTROMYOGRAPHY; EVOKED MUSCLE RESPONSE; HOFFMANN REFLEX; IMMUNOREACTIVITY; MALE; MUSCLE RIGIDITY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPASTICITY; SPINAL CORD ISCHEMIA; WESTERN BLOTTING;

ANIMALS; ASTROCYTES; CELLS, CULTURED; GENE EXPRESSION REGULATION; MALE; MUSCLE RIGIDITY; MUSCLE SPASTICITY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, AMPA; SPINAL CORD; SPINAL CORD ISCHEMIA;

EID: 35448933957     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0989-07.2007     Document Type: Article

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