메뉴 건너뛰기




Volumn 46, Issue 42, 2007, Pages 11979-11986

Cholesterol efflux from macrophage foam cells is enhanced by active phospholipid transfer protein through generation of two types of acceptor particles

Author keywords

[No Author keywords available]

Indexed keywords

ACCEPTOR PARTICLES; CHOLESTEROL EFFLUX; MACROPHAGE FOAM CELLS; PHOSPHOLIPID TRANSFER PROTEIN (PLTP);

EID: 35448931674     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi700833h     Document Type: Article
Times cited : (45)

References (53)
  • 1
    • 0028887870 scopus 로고
    • Molecular physiology of reverse cholesterol transport
    • Fielding, C. J., and Fielding, P. E. (1995) Molecular physiology of reverse cholesterol transport, J. Lipid Res. 36, 211-228.
    • (1995) J. Lipid Res , vol.36 , pp. 211-228
    • Fielding, C.J.1    Fielding, P.E.2
  • 2
    • 3042798281 scopus 로고    scopus 로고
    • ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins
    • Wang, N., Lan, D., Chen, W., Matsuura, F., and Tall, A. R. (2004) ATP-binding cassette transporters G1 and G4 mediate cellular cholesterol efflux to high-density lipoproteins, Proc. Natl. Acad. Sci. U.S.A. 101, 9774-9779.
    • (2004) Proc. Natl. Acad. Sci. U.S.A , vol.101 , pp. 9774-9779
    • Wang, N.1    Lan, D.2    Chen, W.3    Matsuura, F.4    Tall, A.R.5
  • 4
    • 0034602387 scopus 로고    scopus 로고
    • ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages
    • Oram, J. F., Lawn, R. M., Garvin, M. R., and Wade, D. P. (2000) ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages, J. Biol. Chem. 275, 34508-34511.
    • (2000) J. Biol. Chem , vol.275 , pp. 34508-34511
    • Oram, J.F.1    Lawn, R.M.2    Garvin, M.R.3    Wade, D.P.4
  • 8
    • 24044483233 scopus 로고    scopus 로고
    • ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins
    • Vaughan, A. M., and Oram, J. F. (2005) ABCG1 redistributes cell cholesterol to domains removable by high density lipoprotein but not by lipid-depleted apolipoproteins, J. Biol. Chem. 280, 30150-30157.
    • (2005) J. Biol. Chem , vol.280 , pp. 30150-30157
    • Vaughan, A.M.1    Oram, J.F.2
  • 9
    • 33845320131 scopus 로고    scopus 로고
    • Molecular regulation of HDL metabolism and function: Implications for novel therapies
    • Rader, D. J. (2006) Molecular regulation of HDL metabolism and function: implications for novel therapies, J. Clin. Invest. 116, 3090-3100.
    • (2006) J. Clin. Invest , vol.116 , pp. 3090-3100
    • Rader, D.J.1
  • 10
    • 0035089679 scopus 로고    scopus 로고
    • The impact of phospholipid transfer protein (PLTP) on HDL metabolism
    • Huuskonen, J., Olkkonen, V. M., Jauhiainen, M., and Ehnholm, C. (2001) The impact of phospholipid transfer protein (PLTP) on HDL metabolism, Atherosclerosis 155, 269-281.
    • (2001) Atherosclerosis , vol.155 , pp. 269-281
    • Huuskonen, J.1    Olkkonen, V.M.2    Jauhiainen, M.3    Ehnholm, C.4
  • 11
    • 0038173268 scopus 로고    scopus 로고
    • High density lipoproteins (HDLs) and atherosclerosis; the unanswered questions
    • Barter, P., Kastelein, J., Nunn, A., and Hobbs, R. (2003) High density lipoproteins (HDLs) and atherosclerosis; the unanswered questions, Atherosclerosis 168, 195-211.
    • (2003) Atherosclerosis , vol.168 , pp. 195-211
    • Barter, P.1    Kastelein, J.2    Nunn, A.3    Hobbs, R.4
  • 12
    • 0021828138 scopus 로고
    • Plasma phospholipid transfer protein enhances transfer and exchange of phospholipids between very low density lipoproteins and high density lipoproteins during lipolysis
    • Tall, A. R., Krumholz, S., Olivecrona, T., and Deckelbaum, R. J. (1985) Plasma phospholipid transfer protein enhances transfer and exchange of phospholipids between very low density lipoproteins and high density lipoproteins during lipolysis, J. Lipid Res. 26, 842-851.
    • (1985) J. Lipid Res , vol.26 , pp. 842-851
    • Tall, A.R.1    Krumholz, S.2    Olivecrona, T.3    Deckelbaum, R.J.4
  • 13
    • 0033559827 scopus 로고    scopus 로고
    • Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels
    • Jiang, X. C., Bruce, C., Mar, J., Lin, M., Ji, Y., Francone, O. L., and Tall, A. R. (1999) Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels, J. Clin. Invest. 103, 907-914.
    • (1999) J. Clin. Invest , vol.103 , pp. 907-914
    • Jiang, X.C.1    Bruce, C.2    Mar, J.3    Lin, M.4    Ji, Y.5    Francone, O.L.6    Tall, A.R.7
  • 14
    • 0027469774 scopus 로고
    • Human plasma phospholipid transfer protein causes high density lipoprotein conversion
    • Jauhiainen, M., Metso, J., Pahlman, R., Blomqvist, S., van Tol, A., and Ehnholm, C. (1993) Human plasma phospholipid transfer protein causes high density lipoprotein conversion, J. Biol. Chem. 268, 4032-4036.
    • (1993) J. Biol. Chem , vol.268 , pp. 4032-4036
    • Jauhiainen, M.1    Metso, J.2    Pahlman, R.3    Blomqvist, S.4    van Tol, A.5    Ehnholm, C.6
  • 15
    • 0027451376 scopus 로고
    • High density lipoprotein conversion mediated by human plasma phospholipid transfer protein
    • Tu, A. Y., Nishida, H. I., and Nishida, T. (1993) High density lipoprotein conversion mediated by human plasma phospholipid transfer protein, J. Biol. Chem. 268, 23098-23105.
    • (1993) J. Biol. Chem , vol.268 , pp. 23098-23105
    • Tu, A.Y.1    Nishida, H.I.2    Nishida, T.3
  • 16
    • 0030040562 scopus 로고    scopus 로고
    • The mechanism of human plasma phospholipid transfer protein-induced enlargement of high-density lipoprotein particles: Evidence for particle fusion
    • Lusa, S., Jauhiainen, M., Metso, J., Somerharju, P., and Ehnholm, C. (1996) The mechanism of human plasma phospholipid transfer protein-induced enlargement of high-density lipoprotein particles: evidence for particle fusion, Biochem. J. 313 (Pt 1), 275-282.
    • (1996) Biochem. J , vol.313 , Issue.PART 1 , pp. 275-282
    • Lusa, S.1    Jauhiainen, M.2    Metso, J.3    Somerharju, P.4    Ehnholm, C.5
  • 18
    • 0038645847 scopus 로고    scopus 로고
    • Degradation of phospholipid transfer protein (PLTP) and PLTP-generated pre-beta-high density lipoprotein by mast cell chymase impairs high affinity efflux of cholesterol from macrophage foam cells
    • Lee, M., Metso, J., Jauhiainen, M., and Kovanen, P. T. (2003) Degradation of phospholipid transfer protein (PLTP) and PLTP-generated pre-beta-high density lipoprotein by mast cell chymase impairs high affinity efflux of cholesterol from macrophage foam cells, J. Biol. Chem. 278, 13539-13545.
    • (2003) J. Biol. Chem , vol.278 , pp. 13539-13545
    • Lee, M.1    Metso, J.2    Jauhiainen, M.3    Kovanen, P.T.4
  • 20
    • 0142042404 scopus 로고    scopus 로고
    • Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells
    • Desrumaux, C. M., Mak, P. A., Boisvert, W. A., Masson, D., Stupack, D., Jauhiainen, M., Ehnholm, C., and Curtiss, L. K. (2003) Phospholipid transfer protein is present in human atherosclerotic lesions and is expressed by macrophages and foam cells, J. Lipid Res. 44, 1453-1461.
    • (2003) J. Lipid Res , vol.44 , pp. 1453-1461
    • Desrumaux, C.M.1    Mak, P.A.2    Boisvert, W.A.3    Masson, D.4    Stupack, D.5    Jauhiainen, M.6    Ehnholm, C.7    Curtiss, L.K.8
  • 21
    • 0037372065 scopus 로고    scopus 로고
    • The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions
    • Laffitte, B. A., Joseph, S. B., Chen, M., Castrillo, A., Repa, J., Wilpitz, D., Mangelsdorf, D., and Tontonoz, P. (2003) The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions, Mol. Cell. Biol. 23, 2182-2191.
    • (2003) Mol. Cell. Biol , vol.23 , pp. 2182-2191
    • Laffitte, B.A.1    Joseph, S.B.2    Chen, M.3    Castrillo, A.4    Repa, J.5    Wilpitz, D.6    Mangelsdorf, D.7    Tontonoz, P.8
  • 23
    • 2642554959 scopus 로고    scopus 로고
    • Emerging roles for phospholipid transfer protein in lipid and lipoprotein metabolism
    • Albers, J. J., and Cheung, M. C. (2004) Emerging roles for phospholipid transfer protein in lipid and lipoprotein metabolism, Curr. Opin. Lipidol. 15, 255-260.
    • (2004) Curr. Opin. Lipidol , vol.15 , pp. 255-260
    • Albers, J.J.1    Cheung, M.C.2
  • 24
    • 33847647524 scopus 로고    scopus 로고
    • Macrophage phospholipid transfer protein deficiency and ApoE secretion: Impact on mouse plasma cholesterol levels and atherosclerosis
    • Liu, R., Hojjati, M. R., Devlin, C. M., Hansen, I. H., and Jiang, X. C. (2007) Macrophage phospholipid transfer protein deficiency and ApoE secretion: impact on mouse plasma cholesterol levels and atherosclerosis, Arterioscler., Thromb., Vasc. Biol. 27, 190-196.
    • (2007) Arterioscler., Thromb., Vasc. Biol , vol.27 , pp. 190-196
    • Liu, R.1    Hojjati, M.R.2    Devlin, C.M.3    Hansen, I.H.4    Jiang, X.C.5
  • 25
    • 33745955859 scopus 로고    scopus 로고
    • Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression
    • Valenta, D. T., Ogier, N., Bradshaw, G., Black, A. S., Bonnet, D. J., Lagrost, L., Curtiss, L. K., and Desrumaux, C. M. (2006) Atheroprotective potential of macrophage-derived phospholipid transfer protein in low-density lipoprotein receptor-deficient mice is overcome by apolipoprotein AI overexpression, Arterioscler., Thromb., Vasc. Biol. 26, 1572-1578.
    • (2006) Arterioscler., Thromb., Vasc. Biol , vol.26 , pp. 1572-1578
    • Valenta, D.T.1    Ogier, N.2    Bradshaw, G.3    Black, A.S.4    Bonnet, D.J.5    Lagrost, L.6    Curtiss, L.K.7    Desrumaux, C.M.8
  • 26
    • 33847018826 scopus 로고    scopus 로고
    • Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development
    • Vikstedt, R., Ye, D., Metso, J., Hildebrand, R. B., Van Berkel, T. J., Ehnholm, C., Jauhiainen, M., and Van Eck, M. (2007) Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development, Arterioscler, Thromb., Vasc. Biol. 27, 578-586.
    • (2007) Arterioscler, Thromb., Vasc. Biol , vol.27 , pp. 578-586
    • Vikstedt, R.1    Ye, D.2    Metso, J.3    Hildebrand, R.B.4    Van Berkel, T.J.5    Ehnholm, C.6    Jauhiainen, M.7    Van Eck, M.8
  • 27
    • 33747149611 scopus 로고    scopus 로고
    • Absence of endogenous phospholipid transfer protein impairs ABCA1-dependent efflux of cholesterol from macrophage foam cells
    • Lee-Rueckert, M., Vikstedt, R., Metso, J., Ehnholm, C., Kovanen, P. T., and Jauhiainen, M. (2006) Absence of endogenous phospholipid transfer protein impairs ABCA1-dependent efflux of cholesterol from macrophage foam cells, J. Lipid Res. 47, 1725-1732.
    • (2006) J. Lipid Res , vol.47 , pp. 1725-1732
    • Lee-Rueckert, M.1    Vikstedt, R.2    Metso, J.3    Ehnholm, C.4    Kovanen, P.T.5    Jauhiainen, M.6
  • 28
    • 0346732306 scopus 로고    scopus 로고
    • Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells
    • Oram, J. F., Wolfbauer, G., Vaughan, A. M., Tang, C., and Albers, J. J. (2003) Phospholipid transfer protein interacts with and stabilizes ATP-binding cassette transporter A1 and enhances cholesterol efflux from cells, Biol. Chem. 278, 52379-52385.
    • (2003) Biol. Chem , vol.278 , pp. 52379-52385
    • Oram, J.F.1    Wolfbauer, G.2    Vaughan, A.M.3    Tang, C.4    Albers, J.J.5
  • 30
    • 0037013325 scopus 로고    scopus 로고
    • Isolation and partial characterization of the inactive and active forms of human plasma phospholipid transfer protein (PLTP)
    • Karkkainen, M., Oka, T., Olkkonen, V. M., Metso, J., Hattori, H., Jauhiainen, M., and Ehnholm, C. (2002) Isolation and partial characterization of the inactive and active forms of human plasma phospholipid transfer protein (PLTP), J. Biol. Chem. 277, 15413-15418.
    • (2002) J. Biol. Chem , vol.277 , pp. 15413-15418
    • Karkkainen, M.1    Oka, T.2    Olkkonen, V.M.3    Metso, J.4    Hattori, H.5    Jauhiainen, M.6    Ehnholm, C.7
  • 31
    • 33745026603 scopus 로고
    • The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum
    • Havel, R. J., Eder, H. A., and Bragdon, J. H. (1955) The distribution and chemical composition of ultracentrifugally separated lipoproteins in human serum, J. Clin. Invest. 34, 1345-1353.
    • (1955) J. Clin. Invest , vol.34 , pp. 1345-1353
    • Havel, R.J.1    Eder, H.A.2    Bragdon, J.H.3
  • 32
    • 0009627006 scopus 로고
    • Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition
    • Goldstein, J. L., Ho, Y. K., Basu, S. K., and Brown, M. S. (1979) Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition, Proc. Natl. Acad. Sci. U.S.A. 76, 333-337.
    • (1979) Proc. Natl. Acad. Sci. U.S.A , vol.76 , pp. 333-337
    • Goldstein, J.L.1    Ho, Y.K.2    Basu, S.K.3    Brown, M.S.4
  • 33
    • 0030879409 scopus 로고    scopus 로고
    • Transformation of high density lipoprotein 2 particles by hepatic lipase and phospholipid transfer protein
    • Marques-Vidal, P., Jauhiainen, M., Metso, J., and Ehnholm, C. (1997) Transformation of high density lipoprotein 2 particles by hepatic lipase and phospholipid transfer protein, Atherosclerosis 133, 87-95.
    • (1997) Atherosclerosis , vol.133 , pp. 87-95
    • Marques-Vidal, P.1    Jauhiainen, M.2    Metso, J.3    Ehnholm, C.4
  • 34
    • 0020335352 scopus 로고
    • Transfer of [14C]-phosphatidylcholine between liposomes and human plasma high density lipoprotein. Partial purification of a transfer-stimulating plasma factor using a rapid transfer assay
    • Damen, J., Regts, J., and Scherphof, G. (1982) Transfer of [14C]-phosphatidylcholine between liposomes and human plasma high density lipoprotein. Partial purification of a transfer-stimulating plasma factor using a rapid transfer assay, Biochim. Biophys. Acta 712, 444-452.
    • (1982) Biochim. Biophys. Acta , vol.712 , pp. 444-452
    • Damen, J.1    Regts, J.2    Scherphof, G.3
  • 35
    • 19444375648 scopus 로고    scopus 로고
    • Determination of human plasma phospholipid transfer protein mass and activity
    • Jauhiainen, M., and Ehnholm, C. (2005) Determination of human plasma phospholipid transfer protein mass and activity, Methods 36, 97-101.
    • (2005) Methods , vol.36 , pp. 97-101
    • Jauhiainen, M.1    Ehnholm, C.2
  • 38
    • 0141459411 scopus 로고    scopus 로고
    • PLTP secreted by HepG2 cells resembles the high-activity PLTP form in human plasma
    • Siggins, S., Jauhiainen, M., Olkkonen, V. M., Tenhunen, J., and Ehnholm, C. (2003) PLTP secreted by HepG2 cells resembles the high-activity PLTP form in human plasma, J. Lipid Res. 44, 1698-1704.
    • (2003) J. Lipid Res , vol.44 , pp. 1698-1704
    • Siggins, S.1    Jauhiainen, M.2    Olkkonen, V.M.3    Tenhunen, J.4    Ehnholm, C.5
  • 40
    • 0029075572 scopus 로고
    • Pig plasma phospholipid transfer protein facilitates HDL interconversion
    • Pussinen, P., Jauhiainen, M., Metso, J., Tyynela, J., and Ehnholm, C. (1995) Pig plasma phospholipid transfer protein facilitates HDL interconversion, J. Lipid Res. 36, 975-985.
    • (1995) J. Lipid Res , vol.36 , pp. 975-985
    • Pussinen, P.1    Jauhiainen, M.2    Metso, J.3    Tyynela, J.4    Ehnholm, C.5
  • 41
    • 8744238304 scopus 로고    scopus 로고
    • Molecular mechanism of reverse cholesterol transport: Reaction of pre-beta-migrating high-density lipoprotein with plasma lecithin/cholesterol acyltransferase
    • Nakamura, Y., Kotite, L., Gan, Y., Spencer, T. A., Fielding, C. J., and Fielding, P. E. (2004) Molecular mechanism of reverse cholesterol transport: reaction of pre-beta-migrating high-density lipoprotein with plasma lecithin/cholesterol acyltransferase, Biochemistry 43, 14811-14820.
    • (2004) Biochemistry , vol.43 , pp. 14811-14820
    • Nakamura, Y.1    Kotite, L.2    Gan, Y.3    Spencer, T.A.4    Fielding, C.J.5    Fielding, P.E.6
  • 45
    • 33845580066 scopus 로고    scopus 로고
    • ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL
    • Vaughan, A. M., and Oram, J. F. (2006) ABCA1 and ABCG1 or ABCG4 act sequentially to remove cellular cholesterol and generate cholesterol-rich HDL, J. Lipid Res. 47, 2433-2443.
    • (2006) J. Lipid Res , vol.47 , pp. 2433-2443
    • Vaughan, A.M.1    Oram, J.F.2
  • 46
    • 0032812981 scopus 로고    scopus 로고
    • Remodelling of high density lipoproteins by plasma factors
    • Rye, K. A., Clay, M. A., and Barter, P. J. (1999) Remodelling of high density lipoproteins by plasma factors, Atherosclerosis 145, 227-238.
    • (1999) Atherosclerosis , vol.145 , pp. 227-238
    • Rye, K.A.1    Clay, M.A.2    Barter, P.J.3
  • 47
    • 0035625680 scopus 로고    scopus 로고
    • Evaluation of phospholipid transfer protein and cholesteryl ester transfer protein as contributors to the generation of pre beta-high-density lipoproteins
    • Lie, J., de Crom, R., Jauhiainen, M., van Gent, T., van Haperen, R., Scheek, L., Jansen, H., Ehnholm, C., and van Tol, A. (2001) Evaluation of phospholipid transfer protein and cholesteryl ester transfer protein as contributors to the generation of pre beta-high-density lipoproteins, Biochem. J. 360, 379-385.
    • (2001) Biochem. J , vol.360 , pp. 379-385
    • Lie, J.1    de Crom, R.2    Jauhiainen, M.3    van Gent, T.4    van Haperen, R.5    Scheek, L.6    Jansen, H.7    Ehnholm, C.8    van Tol, A.9
  • 49
    • 33947119204 scopus 로고    scopus 로고
    • Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways
    • Wang, M. D., Kiss, R. S., Franklin, V., McBride, H. M., Whitman, S. C., and Marcel, Y. L. (2007) Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways, J. Lipid Res. 48, 633-645.
    • (2007) J. Lipid Res , vol.48 , pp. 633-645
    • Wang, M.D.1    Kiss, R.S.2    Franklin, V.3    McBride, H.M.4    Whitman, S.C.5    Marcel, Y.L.6
  • 51
    • 0029812987 scopus 로고    scopus 로고
    • Fournier, N., de la Llera, Moya, M., Burkey, B. F., Swaney, J. B., Paterniti, J., Jr., Moatti, N., Atger, V., and Rothblat, G. H. (1996) Role of HDL phospholipid in efflux of cell cholesterol to whole serum: studies with human apoA-I transgenic rats, J. Lipid Res. 37, 1704-1711.
    • Fournier, N., de la Llera, Moya, M., Burkey, B. F., Swaney, J. B., Paterniti, J., Jr., Moatti, N., Atger, V., and Rothblat, G. H. (1996) Role of HDL phospholipid in efflux of cell cholesterol to whole serum: studies with human apoA-I transgenic rats, J. Lipid Res. 37, 1704-1711.
  • 53
    • 33646409606 scopus 로고    scopus 로고
    • HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway
    • Matsuura, F., Wang, N., Chen, W., Jiang, X. C., and Tall, A. R. (2006) HDL from CETP-deficient subjects shows enhanced ability to promote cholesterol efflux from macrophages in an apoE- and ABCG1-dependent pathway, J. Clin. Invest. 116, 1435-1442.
    • (2006) J. Clin. Invest , vol.116 , pp. 1435-1442
    • Matsuura, F.1    Wang, N.2    Chen, W.3    Jiang, X.C.4    Tall, A.R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.