메뉴 건너뛰기




Volumn 13, Issue 7, 2004, Pages 777-785

Novel agents for the control of secretory diarrhoea

Author keywords

5 hydroxytryptamine; Acute diarrhoea; Antisecretory drugs; Enkephalins; Enteric nerves; Enterotoxins; Intestinal secretion; Substance P; Vasoactive intestinal polypeptide 1

Indexed keywords

ACETORPHAN; AMINOBENZOIC ACID DERIVATIVE; ANTIBIOTIC AGENT; ANTIDIARRHEAL AGENT; CHLORIDE CHANNEL; CHLORIDE CHANNEL BLOCKING AGENT; CHLORPROMAZINE; CROFELEMER; DIPHENOXYLATE; ENKEPHALIN; ENKEPHALINASE INHIBITOR; GLIBENCLAMIDE; INFUSION FLUID; KETANSERIN; LOPERAMIDE; NEUROHORMONE; OCTREOTIDE; OPIATE AGONIST; ORAL REHYDRATION SOLUTION; RHODANINE; SEROTONIN; SEROTONIN ANTAGONIST; SIGMA OPIATE RECEPTOR; SOMATOSTATIN DERIVATIVE; STILBENEDISULFONIC ACID; SUBSTANCE P; SUBSTANCE P ANTAGONIST; UNINDEXED DRUG; VASOACTIVE INTESTINAL POLYPEPTIDE; VASOACTIVE INTESTINAL POLYPEPTIDE ANTAGONIST; ZALDARIDE MALEATE;

EID: 3543146039     PISSN: 13543784     EISSN: None     Source Type: Journal    
DOI: 10.1517/13543784.13.7.777     Document Type: Review
Times cited : (11)

References (72)
  • 1
    • 0002848974 scopus 로고    scopus 로고
    • Acute diarrhea: Pathophysiology
    • M Gracey. JA Walker-Smith (Eds), Vevey/Lippincott-Raven Publishers, Philadelphia
    • FARTHING MJG: Acute diarrhea: pathophysiology. In: Diarrbeal Disease (Vol. 38). M Gracey. JA Walker-Smith (Eds), Vevey/Lippincott-Raven Publishers, Philadelphia (1997):55-71.
    • (1997) Diarrbeal Disease , vol.38 , pp. 55-71
    • Farthing, M.J.G.1
  • 4
    • 0342539114 scopus 로고    scopus 로고
    • Dehydration and rehydration in children
    • MJ Arnaud (Ed.), John Libbey Eurotext, Paris
    • FARTHING MJG: Dehydration and rehydration in children. In: Hydration Throughout Life. MJ Arnaud (Ed.), John Libbey Eurotext, Paris (1998):159-173.
    • (1998) Hydration Throughout Life , pp. 159-173
    • Farthing, M.J.G.1
  • 5
    • 0003084834 scopus 로고
    • Molecular mechanisms of bacterial toxins
    • MJG Farthing, GT Keusch (Eds), Chapman & Hall, London
    • RAO MC: Molecular mechanisms of bacterial toxins. In: Enteric infection. MJG Farthing, GT Keusch (Eds), Chapman & Hall, London (1989):87-104.
    • (1989) Enteric Infection , pp. 87-104
    • Rao, M.C.1
  • 6
    • 0024427991 scopus 로고
    • Intestinal electrolyte transport and diarrheal disease
    • FIELD M, FAO MC, CHANG EB: Intestinal electrolyte transport and diarrheal disease. N. Engl. J. Med. (1989) 321:879-883.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 879-883
    • Field, M.1    Fao, M.C.2    Chang, E.B.3
  • 7
    • 0024427991 scopus 로고
    • Intestinal electrolyte transport and diarrheal disease
    • FIELD M, RAO MC, CHANG EB: Intestinal electrolyte transport and diarrheal disease. N. Engl. J. Med. (1989) 321:800-806.
    • (1989) N. Engl. J. Med. , vol.321 , pp. 800-806
    • Field, M.1    Rao, M.C.2    Chang, E.B.3
  • 8
    • 0021902511 scopus 로고
    • Toxins which activate guanylate cyclase: Heat-stable enterotoxins
    • D Evered, J Whelan (Eds), Ciba Foundation Symposium 112, Pirman, London
    • RAO MC: Toxins which activate guanylate cyclase: heat-stable enterotoxins. In: Microbial Toxins and Diarrhoeal Disease. D Evered, J Whelan (Eds), Ciba Foundation Symposium 112, Pirman, London (1985):74-93.
    • (1985) Microbial Toxins and Diarrhoeal Disease , pp. 74-93
    • Rao, M.C.1
  • 9
    • 0034469131 scopus 로고    scopus 로고
    • A functional NS94 enterotoxin peptide secreted from rotavirus-infected cells
    • ZHANG M, ZENG CO-Y, MORRIS AP, ESTES MK: A functional NS94 enterotoxin peptide secreted from rotavirus-infected cells. J. Virol. (2000) 74:11663-11670.
    • (2000) J. Virol. , vol.74 , pp. 11663-11670
    • Zhang, M.1    Zeng, C.O.-Y.2    Morris, A.P.3    Estes, M.K.4
  • 10
    • 0034665439 scopus 로고    scopus 로고
    • Mutations selected in rotavirus enterotoxin NSP4 depend on the context of its expression
    • MOHAN KVK, DERMODY TS, ATREYA CD: Mutations selected in rotavirus enterotoxin NSP4 depend on the context of its expression. Virology (2000) 275:125-132.
    • (2000) Virology , vol.275 , pp. 125-132
    • Mohan, K.V.K.1    Dermody, T.S.2    Atreya, C.D.3
  • 11
    • 0034880264 scopus 로고    scopus 로고
    • Microbes and microbial toxins: Paradigms for microbial-mucosal interactions VIII. Pathological consequences of rotavirus infection and its enterotoxin
    • MORRIS AP, ESTES MK: Microbes and microbial toxins: Paradigms for microbial-mucosal interactions VIII. Pathological consequences of rotavirus infection and its enterotoxin. Am. J. Physiol. (2001) 281:G303-G310.
    • (2001) Am. J. Physiol. , vol.281
    • Morris, A.P.1    Estes, M.K.2
  • 12
    • 0026340818 scopus 로고
    • 5-Hydroxytryptamine and 5-hydroxytryptamine 3 receptor antagonists
    • FARTHING MJG: 5-Hydroxytryptamine and 5-hydroxytryptamine 3 receptor antagonists. Scand J. Gastroenterol. (1991) 188(Suppl.):92-100.
    • (1991) Scand. J. Gastroenterol. , vol.188 , Issue.SUPPL. , pp. 92-100
    • Farthing, M.J.G.1
  • 13
    • 0020633262 scopus 로고
    • 5-Hydroxytryptamine and cholera secretion: A histochemical and physiological study in cats
    • NILSSON O, CASSUTO J, LARSSON PA et al.: 5-Hydroxytryptamine and cholera secretion: a histochemical and physiological study in cats. Gut (1983) 24:542-548.
    • (1983) Gut , vol.24 , pp. 542-548
    • Nilsson, O.1    Cassuto, J.2    Larsson, P.A.3
  • 15
    • 0024586843 scopus 로고
    • 2 and cyclic adenosine monophosphate in cholera toxin-induced fluid secretion in the small intestine of the rat in vivo
    • 2 and cyclic adenosine monophosphate in cholera toxin-induced fluid secretion in the small intestine of the rat in vivo. Gastroenterology (1989) 96:368-376.
    • (1989) Gastroenterology , vol.96 , pp. 368-376
    • Beubler, E.1    Kollar, G.2    Saria, A.3    Bukhave, K.4    Rask-Madsen, J.5
  • 16
    • 0029964719 scopus 로고    scopus 로고
    • 5-Hydroxytryptamine release into human jejunum by cholera toxin
    • BEARCROFT CP, PERRETT D, FARTHING MJG: 5-Hydroxytryptamine release into human jejunum by cholera toxin. Gut (1996) 39:528-531.
    • (1996) Gut , vol.39 , pp. 528-531
    • Bearcroft, C.P.1    Perrett, D.2    Farthing, M.J.G.3
  • 17
    • 0025193572 scopus 로고
    • 3 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion
    • 3 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion. Gastroenterology (1990) 99:83-89.
    • (1990) Gastroenterology , vol.99 , pp. 83-89
    • Beubler, E.1    Horina, G.2
  • 18
    • 0026710430 scopus 로고
    • Actions of serotonin antagonists on cholera-induced intestinal fluid secretion
    • SJOQVIST A, CASSUTO J, JODAL M, LUNDGREN O: Actions of serotonin antagonists on cholera-induced intestinal fluid secretion. Acta Physiol. Scand. (1992) 145:229-237.
    • (1992) Acta Physiol. Scand. , vol.145 , pp. 229-237
    • Sjoqvist, A.1    Cassuto, J.2    Jodal, M.3    Lundgren, O.4
  • 19
    • 0029082876 scopus 로고
    • Role of 5-hydroxytryptamine type 3 receptors in rat intestinal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins
    • MOURAD FH, O'DONNELL LJ, DIAS JA et al.: Role of 5-hydroxytryptamine type 3 receptors in rat intestinal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins. Gut (1995) 37:340-345.
    • (1995) Gut , vol.37 , pp. 340-345
    • Mourad, F.H.1    O'Donnell, L.J.2    Dias, J.A.3
  • 20
    • 0035006739 scopus 로고    scopus 로고
    • Cholera toxin induces prostaglandin synthesis via post-transcriptional activation of cyclooxygenase-2 in the rat jejunum
    • BEUBLER E, SCHULIGOI R, CHOPRA AK, RIBARDO DA, PESKAR BA: Cholera toxin induces prostaglandin synthesis via post-transcriptional activation of cyclooxygenase-2 in the rat jejunum. J. Path. Exp. Therap. (2002) 297:940-945.
    • (2002) J. Path. Exp. Therap. , vol.297 , pp. 940-945
    • Beubler, E.1    Schuligoi, R.2    Chopra, A.K.3    Ribardo, D.A.4    Peskar, B.A.5
  • 21
    • 0000244816 scopus 로고    scopus 로고
    • Substance P (SP) antagonist inhibits cholera toxin but not E. coli enterotoxin-induced secretion
    • TURVILL JL, FARTHING MJG: Substance P (SP) antagonist inhibits cholera toxin but not E. coli enterotoxin-induced secretion. Gastroenterology (1999) 112-A414.
    • (1999) Gastroenterology , vol.112
    • Turvill, J.L.1    Farthing, M.J.G.2
  • 22
    • 0033774008 scopus 로고    scopus 로고
    • Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum
    • TURVILL JL, CONNOR P, FARTHING MJG: Neurokinin 1 and 2 receptors mediate cholera toxin secretion in rat jejunum. Gastroenterology (2000) 119:1037-1044.
    • (2000) Gastroenterology , vol.119 , pp. 1037-1044
    • Turvill, J.L.1    Connor, P.2    Farthing, M.J.G.3
  • 23
    • 0028013431 scopus 로고
    • ICP-96,345, a substance P antagonist inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin
    • POTHOULAKIS H, CATAGLIUOLO I, LAMONT T et al.: ICP-96,345, a substance P antagonist inhibits rat intestinal responses to Clostridium difficile toxin A but not cholera toxin. Proc. Natl. Acad. Sci. USA (1994) 91:947-951.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 947-951
    • Pothoulakis, H.1    Catagliuolo, I.2    Lamont, T.3
  • 24
    • 0028129331 scopus 로고
    • Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio enterotoxin in rat ileum
    • CASTAGLUIOLO I, LAMONT JT, LETOURNEAU R et al.: Neuronal involvement in the intestinal effects of Clostridium difficile toxin A and Vibrio enterotoxin in rat ileum. Gastroenterology (1994) 107:657-665.
    • (1994) Gastroenterology , vol.107 , pp. 657-665
    • Castagluiolo, I.1    Lamont, J.T.2    Letourneau, R.3
  • 25
    • 0033695164 scopus 로고    scopus 로고
    • Novel targets for the pharmacotherapy of diarrhoea - A view for the millennium
    • FARTHING MICHAEL JG: Novel targets for the pharmacotherapy of diarrhoea - a view for the millennium. J. Gastroenterol. Hepatol. (2000) 15(Suppl.):C40-C47.
    • (2000) J. Gastroenterol. Hepatol. , vol.15 , Issue.SUPPL.
    • Farthing, M.J.G.1
  • 26
    • 0242579287 scopus 로고    scopus 로고
    • Novel targets for the control of secretory diarrhoea
    • FARTHING MJG: Novel targets for the control of secretory diarrhoea. Gut (2002) 50(Suppl. 3):1-3.
    • (2002) Gut , vol.50 , Issue.SUPPL. 3 , pp. 1-3
    • Farthing, M.J.G.1
  • 27
    • 0142030028 scopus 로고    scopus 로고
    • Getting control of intestinal secretion: Thoughts for 2003
    • FARTHING MJG, CASBURN-JONES A, BANKS MR: Getting control of intestinal secretion: thoughts for 2003. Dig. Liv. Dis. (2003) 35:378-385.
    • (2003) Dig. Liv. Dis. , vol.35 , pp. 378-385
    • Farthing, M.J.G.1    Casburn-Jones, A.2    Banks, M.R.3
  • 28
    • 0022031583 scopus 로고
    • Intestinal nerves and ion transport: Stimuli, reflexes and responses
    • HUBEL KA: Intestinal nerves and ion transport: stimuli, reflexes and responses. Am. J. Physiol. (1985) 248:G261-G271.
    • (1985) Am. J. Physiol. , vol.248
    • Hubel, K.A.1
  • 29
    • 0025353798 scopus 로고
    • Neuronal influence on intestinal transport
    • JODAL M: Neuronal influence on intestinal transport. J. Intern. Med. (1990) 228:125-132.
    • (1990) J. Intern. Med. , vol.228 , pp. 125-132
    • Jodal, M.1
  • 30
    • 0034519915 scopus 로고    scopus 로고
    • Neurotransmitters in neuronal reflexes regulating intestinal secretion
    • COOKE HJ: Neurotransmitters in neuronal reflexes regulating intestinal secretion. Ann. AT Acad. Sci. (2000) 915:77-80.
    • (2000) Ann. AT Acad. Sci. , vol.915 , pp. 77-80
    • Cooke, H.J.1
  • 31
    • 0034438577 scopus 로고    scopus 로고
    • The role of neuroenteric hormones in intestinal infectious diseases
    • POTHOULAKIS C: The role of neuroenteric hormones in intestinal infectious diseases. Curr. Opin. Gastroenterol. (2000) 16:536-540.
    • (2000) Curr. Opin. Gastroenterol. , vol.16 , pp. 536-540
    • Pothoulakis, C.1
  • 32
    • 1642427237 scopus 로고    scopus 로고
    • Cholera toxin (CT), Escherichia coli heat labile (LT) and heat stable toxin (STA) have an indirect effect on distal intestinal fluid transport in the rat small intestine
    • BANKS MR, CASBURN-JONES AC, FARTHING MJG: Cholera toxin (CT), Escherichia coli heat labile (LT) and heat stable toxin (STA) have an indirect effect on distal intestinal fluid transport in the rat small intestine. Gut (2002) (Suppl. II) A69.
    • (2002) Gut , Issue.SUPPL. II
    • Banks, M.R.1    Casburn-Jones, A.C.2    Farthing, M.J.G.3
  • 33
    • 3543074376 scopus 로고    scopus 로고
    • Cholera toxin (CT) Escherichia coli heat labile toxin (LT) and heat stable toxin (STA) have a direct effect on the neuronal-like PC12 cell line
    • CASBURN-JONES AC, BARNETT SC, FITZGERALD UF, FARTHING MJG: Cholera toxin (CT) Escherichia coli heat labile toxin (LT) and heat stable toxin (STA) have a direct effect on the neuronal-like PC12 cell line. Gut (2002) (Suppl. II) A26.
    • (2002) Gut , Issue.SUPPL. II
    • Casburn-Jones, A.C.1    Barnett, S.C.2    Fitzgerald, U.F.3    Farthing, M.J.G.4
  • 34
    • 3543142155 scopus 로고    scopus 로고
    • Bacterial enterotoxins stimulate release of the neurotransmitter [3H] noradrenaline fiorn neuronally differentiated PC 12 cells
    • (In press)
    • CASBURN-JONES AC, BARNETT SC, FARTHING MJG: Bacterial enterotoxins stimulate release of the neurotransmitter [3H] noradrenaline fiorn neuronally differentiated PC 12 cells. Gut (2004) (In press).
    • (2004) Gut
    • Casburn-Jones, A.C.1    Barnett, S.C.2    Farthing, M.J.G.3
  • 35
    • 3543115305 scopus 로고    scopus 로고
    • Identification of differentially expressed genes following bacterial enterotoxin-induced neuronal growth and differentiation in PC12 cells
    • (In press)
    • CASBURN-JONES AC, YOUNG C, HERZYK P, RIBOLDI-TUNNICLIFFE G, FARTHING MJG: Identification of differentially expressed genes following bacterial enterotoxin-induced neuronal growth and differentiation in PC12 cells. Gut (2004) (In press).
    • (2004) Gut
    • Casburn-Jones, A.C.1    Young, C.2    Herzyk, P.3    Riboldi-Tunnicliffe, G.4    Farthing, M.J.G.5
  • 36
    • 0034695527 scopus 로고    scopus 로고
    • Role of the enteric nervous system in the fluid and electrolyte secretion of rotavirus diarrhea
    • LUNDGREN O, PEREGRIN AT, PERSSON K, KORDASTI S, UHNOO I, SVENSSON L: Role of the enteric nervous system in the fluid and electrolyte secretion of rotavirus diarrhea. Science (2000) 287:491-495.
    • (2000) Science , vol.287 , pp. 491-495
    • Lundgren, O.1    Peregrin, A.T.2    Persson, K.3    Kordasti, S.4    Uhnoo, I.5    Svensson, L.6
  • 37
    • 0025353798 scopus 로고
    • Neuronal influence on intestinal transport
    • JODAL M: Neuronal influence on intestinal transport. J. Intern. Med. (1990) 228:125-132.
    • (1990) J. Intern. Med. , vol.228 , pp. 125-132
    • Jodal, M.1
  • 38
    • 0019857433 scopus 로고
    • Release of vasoactive intestinal polypeptide from the cat small intestine exposed to cholera toxin
    • CASSUTO J, FAHRENKRUG J, JODAL M, TUTTLE R, LUNDGREN O: Release of vasoactive intestinal polypeptide from the cat small intestine exposed to cholera toxin. Gut (1981) 22:958-963.
    • (1981) Gut , vol.22 , pp. 958-963
    • Cassuto, J.1    Fahrenkrug, J.2    Jodal, M.3    Tuttle, R.4    Lundgren, O.5
  • 40
    • 0033850197 scopus 로고    scopus 로고
    • Effect of vasoactive intestinal peptide (VIP) antagonism on rat jejunal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins
    • MOURAD FH, NASSAR C: Effect of vasoactive intestinal peptide (VIP) antagonism on rat jejunal fluid and electrolyte secretion induced by cholera and Escherichia coli enterotoxins. Gut (2000) 47:382-386.
    • (2000) Gut , vol.47 , pp. 382-386
    • Mourad, F.H.1    Nassar, C.2
  • 41
    • 3543135125 scopus 로고    scopus 로고
    • Antisecretory actions of a novel vasoactive intestinal polypeptide receptor antagonist
    • BANKS MR, FARTHING MJG, ROBBERECHT P, BURLEIGH DE: Antisecretory actions of a novel vasoactive intestinal polypeptide receptor antagonist. Gastroenterology (2002) 122(4):A254.
    • (2002) Gastroenterology , vol.122 , Issue.4
    • Banks, M.R.1    Farthing, M.J.G.2    Robberecht, P.3    Burleigh, D.E.4
  • 42
    • 0032832268 scopus 로고    scopus 로고
    • The sigma ligand, igmesine, inhibits cholera toxin and Escherichia coli enterotoxin induced jejunal secretion in the rat
    • TURVILL JL, KASAPIDIS P, FARTHING MJG: The sigma ligand, igmesine, inhibits cholera toxin and Escherichia coli enterotoxin induced jejunal secretion in the rat. Gut (1999) 45:564-569.
    • (1999) Gut , vol.45 , pp. 564-569
    • Turvill, J.L.1    Kasapidis, P.2    Farthing, M.J.G.3
  • 43
    • 0029946788 scopus 로고    scopus 로고
    • The role of somatostatin analogues in the treatment of refractory diarrhoea
    • FARTHING MJG: The role of somatostatin analogues in the treatment of refractory diarrhoea. Digestion (1996) 57:107-112.
    • (1996) Digestion , vol.57 , pp. 107-112
    • Farthing, M.J.G.1
  • 44
    • 0032955693 scopus 로고    scopus 로고
    • Octreotide in the treatment of refractory diarthea
    • FRIED M: Octreotide in the treatment of refractory diarthea. Digestion (1999) 60:42-46.
    • (1999) Digestion , vol.60 , pp. 42-46
    • Fried, M.1
  • 45
    • 0029959706 scopus 로고    scopus 로고
    • Efficacy of octreotide in diarrhoea due to Vibrio cholerae: A randomized, controlled trial
    • ABBAS Z MOID I, KHAN AH et al.: Efficacy of octreotide in diarrhoea due to Vibrio cholerae: a randomized, controlled trial. Ann. Trop. Med. Parasitol. (1996) 90:507-513.
    • (1996) Ann. Trop. Med. Parasitol. , vol.90 , pp. 507-513
    • Abbas, Z.1    Moid, I.2    Khan, A.H.3
  • 46
    • 0027999248 scopus 로고
    • Octreotide therapy of large-volume refractory AIDS-asociated diarrhea: A randomized controlled trial
    • GARCIA COMPEAN D, RAMOS JIMENEZ J, GUZMAN DE LA GARZA F et al.: Octreotide therapy of large-volume refractory AIDS-asociated diarrhea: a randomized controlled trial. AIDS (1994) 8:1563-1567
    • (1994) AIDS , vol.8 , pp. 1563-1567
    • Garcia, C.D.1    Ramos, J.J.2    Guzman De La Garza, F.3
  • 47
    • 0035666154 scopus 로고    scopus 로고
    • Systematic review: The use of somatostatin or octreotide in refractory diarrhoea
    • SZILAGYI A, SHRIER I: Systematic review: the use of somatostatin or octreotide in refractory diarrhoea. Aliment. Pharmacol. Therap. (2001) 15:189-197.
    • (2001) Aliment. Pharmacol. Therap. , vol.15 , pp. 189-197
    • Szilagyi, A.1    Shrier, I.2
  • 48
    • 0030870645 scopus 로고    scopus 로고
    • Enkephalins and enkephalinase inhibitors in intestinal fluid and electrolyte transport
    • TURVILL JL, FARTHING MJG: Enkephalins and enkephalinase inhibitors in intestinal fluid and electrolyte transport Eur. J. Gastro. Hepatol. (1997) 9:877-880.
    • (1997) Eur. J. Gastro. Hepatol. , vol.9 , pp. 877-880
    • Turvill, J.L.1    Farthing, M.J.G.2
  • 49
    • 0033371816 scopus 로고    scopus 로고
    • Enkephalinase inhibitiori: A rational approach to antisecretary therapy for acute diarrhoea
    • FARTHING MJG: Enkephalinase inhibitiori: a rational approach to antisecretary therapy for acute diarrhoea. Aliment. Pharmacol. Ther. (1999) 13(Suppl. 6):1-2.
    • (1999) Aliment. Pharmacol. Ther. , vol.13 , Issue.SUPPL. 6 , pp. 1-2
    • Farthing, M.J.G.1
  • 52
    • 0034008625 scopus 로고    scopus 로고
    • An overview of clinical studies with racecadotril in adults
    • LECOMTE JM: An overview of clinical studies with racecadotril in adults. Int. J. Antimicrob. Agents (2000) 14:81-87
    • (2000) Int. J. Antimicrob. Agents , vol.14 , pp. 81-87
    • Lecomte, J.M.1
  • 53
    • 0035990156 scopus 로고    scopus 로고
    • A multinational comparison of racecadotril and loperamide in the treatment of watery diarrhoea in adults
    • PRADO D: A multinational comparison of racecadotril and loperamide in the treatment of watery diarrhoea in adults. Scand J. Gastroenterol. (2002) 37:656-661.
    • (2002) Scand. J. Gastroenterol. , vol.37 , pp. 656-661
    • Prado, D.1
  • 54
    • 0033396027 scopus 로고    scopus 로고
    • Comparison of racecadotril and loperamide in children with acute diarrhoea
    • TURCK D, BERARD H, FRETAULT N, LECOMTE JM: Comparison of racecadotril and loperamide in children with acute diarrhoea. Aliment. Pharmacol. Ther. (1999) 13(Suppl. 6):27-32.
    • (1999) Aliment. Pharmacol. Ther. , vol.13 , Issue.SUPPL. 6 , pp. 27-32
    • Turck, D.1    Berard, H.2    Fretault, N.3    Lecomte, J.M.4
  • 55
    • 0035120299 scopus 로고    scopus 로고
    • Efficacy and tolerability of racecadotril in acute diarrhea in children
    • CEZARD JP, DUHAMEL JF, MEYER M et al.: Efficacy and tolerability of racecadotril in acute diarrhea in children. Gastroenterology (2001) 120:799-805
    • (2001) Gastroenterology , vol.120 , pp. 799-805
    • Cezard, J.P.1    Duhamel, J.F.2    Meyer, M.3
  • 57
    • 0007007704 scopus 로고
    • Pharmacological approaches to treatment of secretory diarrhoea
    • M Field, JS Fordtran, SG Schultz (Eds), American Physiological Society, Bethesda, MD, USA
    • POWELL DW, FIELD M: Pharmacological approaches to treatment of secretory diarrhoea. In: Secretory Diarrhea. M Field, JS Fordtran, SG Schultz (Eds), American Physiological Society, Bethesda, MD, USA (1980):187-209.
    • (1980) Secretory Diarrhea , pp. 187-209
    • Powell, D.W.1    Field, M.2
  • 58
    • 0034647090 scopus 로고    scopus 로고
    • Effect of zaldaride maleate, an antidiarrheal compound, on intracellular cyclic nucleotide-mediated intestinal ion secretion in rats
    • AIKAWA N, KARASAWA A, OHMORI K: Effect of zaldaride maleate, an antidiarrheal compound, on intracellular cyclic nucleotide-mediated intestinal ion secretion in rats. Eur. J. Pharmacol. (2000) 394:233-236
    • (2000) Eur. J. Pharmacol. , vol.394 , pp. 233-236
    • Aikawa, N.1    Karasawa, A.2    Ohmori, K.3
  • 59
    • 20244368791 scopus 로고
    • Treatment of traveller's diarrhoea: Zaldaride compared with loperamide and placebo
    • SILBERSCHMIDT G, SCHICK MT, STEFFEN R et al.: Treatment of traveller's diarrhoea: zaldaride compared with loperamide and placebo. Eur. J. Gastroenterol. Hepatol. (1995) 7:871-875.
    • (1995) Eur. J. Gastroenterol. Hepatol. , vol.7 , pp. 871-875
    • Silberschmidt, G.1    Schick, M.T.2    Steffen, R.3
  • 60
    • 0029085463 scopus 로고
    • Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler's diarrhoea: A randomised, placebo-controlled trial
    • OKHUYSEN PC, DUPONT HL, ERICSSON CD et al.: Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler's diarrhoea: a randomised, placebo-controlled trial. Clin. Infect. Dis. (1995)21:341-344.
    • (1995) Clin. Infect. Dis. , vol.21 , pp. 341-344
    • Okhuysen, P.C.1    Dupont, H.L.2    Ericsson, C.D.3
  • 62
    • 0032832785 scopus 로고    scopus 로고
    • Inhibition of heterologously expressed cystic fibrosis transmembrane conductance regulator CT channels by nonsulphonylurea hypoglycaemic agents
    • CAI Z, LANDSELL KA, SHEPPARD DN: Inhibition of heterologously expressed cystic fibrosis transmembrane conductance regulator CT channels by nonsulphonylurea hypoglycaemic agents. Br. J. Pharmacol. (1999)128:108-118.
    • (1999) Br. J. Pharmacol. , vol.128 , pp. 108-118
    • Cai, Z.1    Landsell, K.A.2    Sheppard, D.N.3
  • 63
    • 0036896008 scopus 로고    scopus 로고
    • Thiazolidinone CFTR inhibitor identified by high throughput screening blocks cholera toxin-induced intestinal fluid secretion
    • MA T, THIAGARAJAH JR, YANG H, et al.: Thiazolidinone CFTR inhibitor identified by high throughput screening blocks cholera toxin-induced intestinal fluid secretion. J. Clin. Invest. (2002) 110:1651-1658.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1651-1658
    • Ma, T.1    Thiagarajah, J.R.2    Yang, H.3
  • 64
    • 0036791746 scopus 로고    scopus 로고
    • A double-blind, randomized, placebo-controlled study of SP 303 (provir) in the symptomatic treatment of acute diarrhea among travelers to Jamaica and Mexico
    • DICESARE D, DUPONT HL, MATHEWSON JJ et al.: A double-blind, randomized, placebo-controlled study of SP 303 (provir) in the symptomatic treatment of acute diarrhea among travelers to Jamaica and Mexico. Am. J. Gastroenterol. (2002)97:2585-2588.
    • (2002) Am. J. Gastroenterol. , vol.97 , pp. 2585-2588
    • Dicesare, D.1    Dupont, H.L.2    Mathewson, J.J.3
  • 65
    • 0036786188 scopus 로고    scopus 로고
    • Antidiarrhoeal properties of a novel sigma ligand (JO 2871) on toxigenic diarrhoea in mice: Mechanisms of action
    • THEODOROU V, CHOVET M, EUTAMENE H et al.: Antidiarrhoeal properties of a novel sigma ligand (JO 2871) on toxigenic diarrhoea in mice: mechanisms of action. Gut (2002)51:522-528
    • (2002) Gut , vol.51 , pp. 522-528
    • Theodorou, V.1    Chovet, M.2    Eutamene, H.3
  • 66
    • 0031708613 scopus 로고    scopus 로고
    • Inhibition of prostaglandin-induced intestinal secretion by igmesine in healthy volunteers
    • ROZE C, BRULEY DES VARANNES S, SHI G, GENEVE J, GALMICHE JP: Inhibition of prostaglandin-induced intestinal secretion by igmesine in healthy volunteers. Gastroenterology (1998)115:591-596.
    • (1998) Gastroenterology , vol.115 , pp. 591-596
    • Roze, C.1    Bruley Des Varannes, S.2    Shi, G.3    Geneve, J.4    Galmiche, J.P.5
  • 67
    • 0025193572 scopus 로고
    • 5-HT3 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion in the rat
    • BEUBLER E, HORINA G: 5-HT3 receptor subtypes mediate cholera toxin-induced intestinal fluid secretion in the rat. Gastroenterology (1990) 99:83-89.
    • (1990) Gastroenterology , vol.99 , pp. 83-89
    • Beubler, E.1    Horina, G.2
  • 68
    • 0024370243 scopus 로고
    • 3 receptor antagonist ICS 205-930
    • 3 receptor antagonist ICS 205-930. Arch. Pharmacol. (1989) 339-704-705.
    • (1989) Arch. Pharmacol. , vol.339 , pp. 704-705
    • Buchheit, K.H.1
  • 70
    • 0030833013 scopus 로고    scopus 로고
    • 3 antagonist alosetron on basal and cholera toxin-induced secretion in the human jejunum: A segmental perfusion
    • 3 antagonist alosetron on basal and cholera toxin-induced secretion in the human jejunum: a segmental perfusion. Aliment. Pharm. Therap. (1997) 11:1109-1114.
    • (1997) Aliment. Pharm. Therap. , vol.11 , pp. 1109-1114
    • Bearcropt, C.P.1    Andre, E.2    Farthing, M.J.G.3
  • 71
    • 0343417066 scopus 로고    scopus 로고
    • Effect of granisetron on cholera toxin-induced enteric secretion
    • TURVILL JL, FARTHING MJG: Effect of granisetron on cholera toxin-induced enteric secretion. Lancet (1997) 349:1293.
    • (1997) Lancet , vol.349 , pp. 1293
    • Turvill, J.L.1    Farthing, M.J.G.2
  • 72
    • 0000825909 scopus 로고    scopus 로고
    • 4) antagonist inhibits cholera toxin (CT) but not E. coli heat labile toxin (LT)-induced secretion
    • 4) antagonist inhibits cholera toxin (CT) but not E. coli heat labile toxin (LT)-induced secretion. Gastroenterology (1996) 110:A368.
    • (1996) Gastroenterology , vol.110
    • Uurvill, J.L.1    Farthing, M.J.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.