D-Serine-induced nephrotoxicity: Possible interaction with tyrosine metabolism

Toxicology

Volumn 201, Issue 1-3, 2004, Pages 231-238

  Williams, R E ^a,b   Lock, E A ^a  

^a JEALOTT S HILL INTERNATIONAL RESEARCH CENTRE   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

2 (2 nitro 4 trifluoromethylbenzoyl) cyclohexane 1,3 dione; 4 hydroxyphenyllactate; 4 hydroxyphenylpyruvate; 4 hydroxyphenylpyruvate dioxygenase; FAH; fumarylacetoacetate hydrolase; HPLA; HPPA; HPPD; N acetyl glucosaminidase; NAG; NTBC; PCA

Indexed keywords

4 HYDROXYPHENYLLACTATE; 4 HYDROXYPHENYLPYRUVATE DIOXYGENASE; 4 HYDROXYPHENYLPYRUVIC ACID; BIOLOGICAL MARKER; CORN OIL; DEXTRO SERINE; FUMARYLACETOACETASE; LACTIC ACID DERIVATIVE; NITISINONE; PYRUVIC ACID DERIVATIVE; TYROSINE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMICAL ANALYSIS; CONTROLLED STUDY; HISTOPATHOLOGY; KIDNEY INJURY; KIDNEY PROXIMAL TUBULE; MALE; MOLECULAR INTERACTION; NEPHROTOXICITY; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REGULATORY MECHANISM; URINALYSIS;

ANIMALS; CYCLOHEXANONES; ENZYME INHIBITORS; HYDROLASES; KIDNEY TUBULES, PROXIMAL; MALE; NITROBENZOATES; PHENYLPYRUVIC ACIDS; RATS; SERINE; TYROSINE;

ZEA MAYS;

EID: 3543135911     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.05.001     Document Type: Article

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