Role of phosphatidylinositol-3 kinase in regulation of differential sensitivity of melanoma cells to antitumor agents. A model for hormone resistance development in tumor cells

Biochemistry (Moscow)

Volumn 69, Issue 3, 2004, Pages 322-330

  Krasil'nikov, M A ^a   Luzai, E V ^a   Scherbakov, A M ^a   Shatskaya, V A ^a   Shtil, A A ^a   Gershtein, E S ^a  

^a INSTITUTE OF BIOMEDICAL CHEMISTRY   (Russian Federation)

Author keywords

Apoptosis; Dexamethasone; Melanoma; Phosphatidylinositol 3 kinase; Protein kinase B; Resistance; STAT3

Indexed keywords

ACTIVATION ANALYSIS; CELLS; ENZYMES; HORMONES; SENSITIVITY ANALYSIS; TUMORS; ULTRAVIOLET RADIATION;

APOPTOSIS; DEXAMETHASONE; MELANOMA; PROTEIN KINASE;

BIOCHEMISTRY;

ANTINEOPLASTIC ANTIBIOTIC; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; DEXAMETHASONE; DNA BINDING PROTEIN; DOXORUBICIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B KINASE; PROTEIN SERINE THREONINE KINASE; STAT3 PROTEIN; STAT3 PROTEIN, HUMAN; TRANSACTIVATOR PROTEIN;

ARTICLE; CELL SURVIVAL; DRUG EFFECT; DRUG RESISTANCE; GENE EXPRESSION REGULATION; HUMAN; MELANOMA; METABOLISM; RADIATION EXPOSURE; SIGNAL TRANSDUCTION; TUMOR CELL LINE; ULTRAVIOLET RADIATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, HORMONAL; CELL LINE, TUMOR; CELL SURVIVAL; DEXAMETHASONE; DNA-BINDING PROTEINS; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MELANOMA; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; ULTRAVIOLET RAYS;

EID: 3543050553     PISSN: 00062979     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:BIRY.0000022065.17006.7d     Document Type: Article

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