Transcytosis of gastric leptin through the rat duodenal mucosa

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 293, Issue 4, 2007, Pages

  Cammisotto, Philippe G ^a   Gingras, Diane ^a   Bendayan, Moïse ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Duodenum; Gastric emptying

Indexed keywords

FLUORESCEIN ISOTHIOCYANATE; LEPTIN; RECOMBINANT HORMONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAPILLARY ENDOTHELIUM; CELL COMPARTMENTALIZATION; CELL MEMBRANE; CHOLINERGIC STIMULATION; CONTROLLED STUDY; DUODENUM MUCOSA; ELECTRON MICROSCOPY; ENDOCYTOSIS; ENDOTHELIUM CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; GASTROINTESTINAL ABSORPTION; GOLGI COMPLEX; HORMONE BLOOD LEVEL; HORMONE RELEASE; IMMUNOCYTOCHEMISTRY; IN VIVO STUDY; INTERNALIZATION; INTESTINE BLOOD FLOW; INTESTINE BRUSH BORDER; INTESTINE CELL; INTESTINE EPITHELIUM CELL; INTESTINE MUCOSA; LAMINA PROPRIA; MALE; MEMBRANE VESICLE; NONHUMAN; NUTRIENT; PARACRINE SIGNALING; PRIORITY JOURNAL; PYLORUS; RAT; STOMACH EMPTYING; STOMACH JUICE; TRANSCYTOSIS; WESTERN BLOTTING;

ANIMALS; CARBACHOL; DUODENUM; ENTEROCYTES; INTESTINAL MUCOSA; LEPTIN; MALE; RATS; RATS, SPRAGUE-DAWLEY; STOMACH;

EID: 35348987538     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00260.2007     Document Type: Article

References (37)

1. Ahima RS, Saper CB, Flier JS, Elmquist JK. Leptin regulation of neuroendocrine systems. Front Neuroendocrinol 21: 263-307, 2000.
2. Anini Y, Brubaker PL. Role of leptin in the regulation of glucagon-like peptide-1 secretion. Diabetes 52: 252-259, 2003.
3. Attoub S, Levasseur S, Buyse M, Goiot H, Laigneau JP, Moizo L, Hervatin F, Le Marchand-Brustel Y, Lewin JM, Bado A. Physiological role of cholecystokinin B/gastrin receptor in leptin secretion. Endocrinology 140: 4406-4410, 1999.
4. Bado A, Levasseur S, Attoub S, Kermorgant S, Laigneau JP, Bortoluzzi MN, Moizo L, Lehy T, Guerre-Millo M, Le Marchand-Brustel Y, Lewin MJ. The stomach is a source of leptin. Nature 394: 790-793, 1998.
5. Barrenetxe J, Villaro AC, Guembe L, Pascual I, Munoz-Navas M, Barber A, Lostao MP. Distribution of the long leptin receptor isoform in brush border, basolateral membrane, and cytoplasm of enterocytes. Gut 50: 797-802, 2006.
6. Bendayan M. Colloidal gold post embedding immunocytochemistry. Prog Histochem Cytochem 29: 1-163, 1995.
7. Bendayan M, Ziv E, Gingras D, Ben-Sasson R, Bar-On H, Kidron M. Biochemical and morpho-cytochemical evidence for the intestinal absorption of insulin in control diabetic rats. Comparison between the effectiveness of duodenal and colon mucosa. Diabetologia 37: 119-126, 1994.
8. Bruneau N, Lombardo D, Bendayan M. Participation of GRP94-related protein in secretion of pancreatic bile salt-dependent lipase and in its internalization by the intestinal epithelium. J Cell Sci 111: 2665-2679, 1998.
9. Bruneau N, Bendayan M, Gingras D, Ghitescu L, Levy E, Lombardo D. Circulating bile salt-dependent lipase originates from the pancreas via intestinal transcytosis. Gastroenterology 124: 470-480, 2003.
10. Cammisotto PG, Renaud C, Gingras D, Delvin E, Levy E, Bendayan M. Endocrine and exocrine secretion of leptin by the gastric mucosa. J Histochem Cytochem 53: 851-860, 2005.
11. Cammisotto PG, Deshaies Y, Bukowiecki L, Bendayan M. Biosynthetic pathway of leptin secretion from white adipocytes. Biochem Cell Biol 84: 207-214, 2006.
12. Cammisotto PG, Gingras D, Renaud C, Levy E, Bendayan M. Secretion of soluble leptin receptors by exocrine and endocrine cells of the gastric mucosa. Am J Physiol Gastrointest Liver Physiol 290: G242-G249, 2006.
13. Cases JA, Gabriely I, Ma XH, Yang XM, Michaeli T, Fleischer N, Rossetti L, Barzilai N. Physiological increase in plasma leptin markedly inhibits insulin secretion in vivo. Diabetes 50: 348-352, 2001.
14. Chaudhri O, Small C, Bloom S. Gastrointestinal hormones regulating appetite. Philos Trans R Soc Lond B Biol Sci 361: 1187-209, 2006.
15. Cloutier M, Gingras D, Bendayan M. Internalization and transcytosis of pancreatic enzymes by the intestinal mucosa. J Histochem Cytochem 54: 781-794, 2006.
16. Considine RV. Human leptin: an adipocyte hormone with weight-regulatory and endocrine functions. Semin Vasc Med 5: 15-24, 2005.
17. Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature 395: 763-770, 1998.
18. Groschl M, Rauh M, Wagner R, Neuhuber W, Metzler M, Tamguney G, Zenk J, Schoof E, Dorr HG, Blum WF, Rascher W, Dotsch J. Identification of leptin in human saliva. J Clin Endocrinol Metab 86: 5234-5239, 2001.
19. Guilmeau S, Buyse M, Tsocas A, Laigneau JP, Bado A. Duodenal leptin stimulates cholecystokinin secretion: evidence of a positive leptin-cholecystokinin feedback loop. Diabetes 52: 1664-1672, 2003.
20. Havel PJ. Role of adipose tissue in body-weight regulation: mechanisms regulating leptin production and energy balance. Proc Nutr Soc 59: 359-371, 2000.
21. Himms-Hagen J. Physiological roles of the leptin endocrine system : differences between mice and humans. Crit Rev Clin Lab Sci 36: 575-655, 1999.
22. Kamegai J, Tamura H, Shimizu T, Ishii S, Sugihara H, Oikawa S. Effects of insulin, leptin, and glucagon on ghrelin secretion from isolated perfused rat stomach. Regul Pept 119: 77-81, 2004.
23. Kiely JM, Noh JH, Pitt HA, Swartz-Basile DA. Impaired intestinal cell proliferation and cell death in leptin-deficient obese mice. J Parenter Enteral Nutr 29: 30-35, 2005.
24. Licinio J, Caglayan S, Ozata M, Yildiz BO, de Miranda PB, O'Kirwan F, Whitby R, Liang L, Cohen P, Bhasin S, Krauss RM, Veldhuis JD, Wagner AJ, DePaoli AM, McCann SM, Wong ML. Phenotypic effects of leptin replacement on morbid obesity, diabetes mellitus, hypogonadism, and behavior in leptin-deficient adults. Proc Natl Acad Sci USA 101: 4531-4536, 2004.
25. Liddle RA. Cholecystokinin cells. Annu Rev Physiol 59: 221-242, 1997.
26. Liu C, Liu XJ, Barry G, Ling N, Maki RA, De Souza EB. Expression and characterization of a putative high affinity human soluble leptin receptor. Endocrinology 138: 3548-3554, 1997.
27. Lollmann B, Gruninger S, Stricker-Krongrad A, Chiesi M. Detection and quantification of the leptin receptor splice variants Ob-Ra, b and e in different mouse tissues. Biochem Biophys Res Commun 238: 648-652, 1997.
28. Lord GM, Matarese G, Howard JK, Baker RJ, Bloom SR, Lechler RI. Leptin modulates the T-cell immune response and reverses starvation-induced immunosuppression. Nature 394: 897-901, 1998.
29. Lostao MP, Urdaneta E, Martinez-Anso E, Barber A, Martinez JA. Presence of leptin receptors in rat small intestine and leptin effect on sugar absorption. FEBS Lett 423: 302-306, 1998.
30. Petersen KF, Oral EA, Dufour S, Befroy D, Ariyan C, Yu C, Cline GW, DePaoli AM, Taylor SI, Gorden P, Shulman GI. Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy. J Clin Invest 109: 1345-1350, 2002.
31. Smith-Kirwin SM, O'Connor DM, De Johnston J, Lancey ED, Hassink SG, Funanage VL. Leptin expression in human mammary epithelial cells and breast milk. J Clin Endocrinol Metab 83: 1810-1813, 1998.
32. Stan S, Levy E, Bendayan M, Zoltowska M, Lambert M, Michaud J, Asselin C, Delvin EE. Effect of human recombinant leptin on lipid handling by fully differentiated Caco-2 cells. FEBS Lett 508: 80-84, 2001.
33. Thorens B. Expression cloning of the pancreatic beta cell receptor for the gluco-incretin hormone glucagon-like peptide 1. Proc Natl Acad Sci USA 89: 8641-8645, 1992.
34. Zhang F, Basinski MB, Beals JM, Briggs SL, Churgay LM, Clawson DK, DiMarchi RD, Furman TC, Hale JE, Hsiung HM, Schoner BE, Smith DP, Zhang XY, Wery JP, Schevitz RW. Crystal structure of the obese protein leptin-E100. Nature 387: 206-209, 1997.
35. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature 372: 425-432, 1995.
36. Ziv E, Bendayan M. Intestinal absorption of peptides through the enterocytes. Microsc Res Tech 49: 346-352, 2000.
37. Ziv E, Lior O, Kidron M. Absorption of protein via the intestinal wall. A quantitative model. Biochem Pharmacol 36: 1035-1039, 1987.